-
1
-
-
0033352861
-
Drosophila UNC-13 is essential for synaptic transmission
-
Aravamudan, B., Fergestad, T., Davis, W.S., Rodesch, C.K., Broadie, K., Drosophila UNC-13 is essential for synaptic transmission. Nat. Neurosci. 2 (1999), 965–971.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 965-971
-
-
Aravamudan, B.1
Fergestad, T.2
Davis, W.S.3
Rodesch, C.K.4
Broadie, K.5
-
2
-
-
0032849774
-
An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system
-
Ashery, U., Betz, A., Xu, T., Brose, N., Rettig, J., An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system. Eur. J. Cell Biol. 78 (1999), 525–532.
-
(1999)
Eur. J. Cell Biol.
, vol.78
, pp. 525-532
-
-
Ashery, U.1
Betz, A.2
Xu, T.3
Brose, N.4
Rettig, J.5
-
3
-
-
0033615054
-
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
-
Augustin, I., Rosenmund, C., Südhof, T.C., Brose, N., Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature 400 (1999), 457–461.
-
(1999)
Nature
, vol.400
, pp. 457-461
-
-
Augustin, I.1
Rosenmund, C.2
Südhof, T.C.3
Brose, N.4
-
4
-
-
84941356670
-
A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
-
Baker, R.W., Jeffrey, P.D., Zick, M., Phillips, B.P., Wickner, W.T., Hughson, F.M., A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science 349 (2015), 1111–1114.
-
(2015)
Science
, vol.349
, pp. 1111-1114
-
-
Baker, R.W.1
Jeffrey, P.D.2
Zick, M.3
Phillips, B.P.4
Wickner, W.T.5
Hughson, F.M.6
-
5
-
-
33645014145
-
A minimal domain responsible for Munc13 activity
-
Basu, J., Shen, N., Dulubova, I., Lu, J., Guan, R., Guryev, O., Grishin, N.V., Rosenmund, C., Rizo, J., A minimal domain responsible for Munc13 activity. Nat. Struct. Mol. Biol. 12 (2005), 1017–1018.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 1017-1018
-
-
Basu, J.1
Shen, N.2
Dulubova, I.3
Lu, J.4
Guan, R.5
Guryev, O.6
Grishin, N.V.7
Rosenmund, C.8
Rizo, J.9
-
6
-
-
84861922902
-
Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
-
Boswell, K.L., James, D.J., Esquibel, J.M., Bruinsma, S., Shirakawa, R., Horiuchi, H., Martin, T.F.J., Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion. J. Cell Biol. 197 (2012), 301–312.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 301-312
-
-
Boswell, K.L.1
James, D.J.2
Esquibel, J.M.3
Bruinsma, S.4
Shirakawa, R.5
Horiuchi, H.6
Martin, T.F.J.7
-
7
-
-
77951114109
-
Munc13-2 differentially affects hippocampal synaptic transmission and plasticity
-
Breustedt, J., Gundlfinger, A., Varoqueaux, F., Reim, K., Brose, N., Schmitz, D., Munc13-2 differentially affects hippocampal synaptic transmission and plasticity. Cereb. Cortex 20 (2010), 1109–1120.
-
(2010)
Cereb. Cortex
, vol.20
, pp. 1109-1120
-
-
Breustedt, J.1
Gundlfinger, A.2
Varoqueaux, F.3
Reim, K.4
Brose, N.5
Schmitz, D.6
-
8
-
-
33644770187
-
Structure and function of SNARE and SNARE-interacting proteins
-
Brunger, A.T., Structure and function of SNARE and SNARE-interacting proteins. Q. Rev. Biophys. 38 (2005), 1–47.
-
(2005)
Q. Rev. Biophys.
, vol.38
, pp. 1-47
-
-
Brunger, A.T.1
-
9
-
-
84937615267
-
Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins
-
Brunger, A.T., Cipriano, D.J., Diao, J., Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins. Crit. Rev. Biochem. Mol. Biol. 50 (2015), 231–241.
-
(2015)
Crit. Rev. Biochem. Mol. Biol.
, vol.50
, pp. 231-241
-
-
Brunger, A.T.1
Cipriano, D.J.2
Diao, J.3
-
10
-
-
84866784016
-
2+ in an autaptic neuron culture system
-
2+ in an autaptic neuron culture system. Nat. Protoc. 7 (2012), 1351–1365.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1351-1365
-
-
Burgalossi, A.1
Jung, S.2
Man, K.N.3
Nair, R.4
Jockusch, W.J.5
Wojcik, S.M.6
Brose, N.7
Rhee, J.-S.8
-
11
-
-
0035034079
-
Sequential SNARE assembly underlies priming and triggering of exocytosis
-
Chen, Y.A., Scales, S.J., Scheller, R.H., Sequential SNARE assembly underlies priming and triggering of exocytosis. Neuron 30 (2001), 161–170.
-
(2001)
Neuron
, vol.30
, pp. 161-170
-
-
Chen, Y.A.1
Scales, S.J.2
Scheller, R.H.3
-
12
-
-
43649085762
-
NMR analysis of the closed conformation of syntaxin-1
-
Chen, X., Lu, J., Dulubova, I., Rizo, J., NMR analysis of the closed conformation of syntaxin-1. J. Biomol. NMR 41 (2008), 43–54.
-
(2008)
J. Biomol. NMR
, vol.41
, pp. 43-54
-
-
Chen, X.1
Lu, J.2
Dulubova, I.3
Rizo, J.4
-
13
-
-
84865345067
-
Immobilization of proteins for single-molecule fluorescence resonance energy transfer measurements of conformation and dynamics
-
Springer New York
-
Choi, U.B., Weninger, K.R., Bowen, M.E., Immobilization of proteins for single-molecule fluorescence resonance energy transfer measurements of conformation and dynamics. Intrinsically Disordered Protein Analysis, 2012, Springer New York, 3–20.
-
(2012)
Intrinsically Disordered Protein Analysis
, pp. 3-20
-
-
Choi, U.B.1
Weninger, K.R.2
Bowen, M.E.3
-
14
-
-
84978804176
-
Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex
-
Choi, U.B., Zhao, M., Zhang, Y., Lai, Y., Brunger, A.T., Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex. eLife, 5, 2016, e16886.
-
(2016)
eLife
, vol.5
, pp. e16886
-
-
Choi, U.B.1
Zhao, M.2
Zhang, Y.3
Lai, Y.4
Brunger, A.T.5
-
15
-
-
84881514823
-
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
-
Diao, J., Grob, P., Cipriano, D.J., Kyoung, M., Zhang, Y., Shah, S., Nguyen, A., Padolina, M., Srivastava, A., Vrljic, M., et al. Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. eLife, 1, 2012, e00109.
-
(2012)
eLife
, vol.1
, pp. e00109
-
-
Diao, J.1
Grob, P.2
Cipriano, D.J.3
Kyoung, M.4
Zhang, Y.5
Shah, S.6
Nguyen, A.7
Padolina, M.8
Srivastava, A.9
Vrljic, M.10
-
16
-
-
0033575749
-
A conformational switch in syntaxin during exocytosis: role of munc18
-
Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernandez, I., Südhof, T.C., Rizo, J., A conformational switch in syntaxin during exocytosis: role of munc18. EMBO J. 18 (1999), 4372–4382.
-
(1999)
EMBO J.
, vol.18
, pp. 4372-4382
-
-
Dulubova, I.1
Sugita, S.2
Hill, S.3
Hosaka, M.4
Fernandez, I.5
Südhof, T.C.6
Rizo, J.7
-
17
-
-
1542320073
-
A transient N-terminal interaction of SNAP-25 and syntaxin nucleates SNARE assembly
-
Fasshauer, D., Margittai, M., A transient N-terminal interaction of SNAP-25 and syntaxin nucleates SNARE assembly. J. Biol. Chem. 279 (2004), 7613–7621.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7613-7621
-
-
Fasshauer, D.1
Margittai, M.2
-
18
-
-
0035282457
-
Synaptotagmin I functions as a calcium regulator of release probability
-
Fernández-Chacón, R., Königstorfer, A., Gerber, S.H.H., García, J., Matos, M.F.F., Stevens, C.F.F., Brose, N., Rizo, J., Rosenmund, C., Südhof, T.C.C., Synaptotagmin I functions as a calcium regulator of release probability. Nature 410 (2001), 41–49.
-
(2001)
Nature
, vol.410
, pp. 41-49
-
-
Fernández-Chacón, R.1
Königstorfer, A.2
Gerber, S.H.H.3
García, J.4
Matos, M.F.F.5
Stevens, C.F.F.6
Brose, N.7
Rizo, J.8
Rosenmund, C.9
Südhof, T.C.C.10
-
19
-
-
0028061861
-
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse
-
Geppert, M., Goda, Y., Hammer, R.E., Li, C., Rosahl, T.W., Stevens, C.F., Südhof, T.C., Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell 79 (1994), 717–727.
-
(1994)
Cell
, vol.79
, pp. 717-727
-
-
Geppert, M.1
Goda, Y.2
Hammer, R.E.3
Li, C.4
Rosahl, T.W.5
Stevens, C.F.6
Südhof, T.C.7
-
20
-
-
85026395703
-
Morphologies of synaptic protein membrane fusion interfaces
-
Published online July 24, 2017
-
Gipson, P., Fukuda, Y., Danev, R., Lai, Y., Chen, D.-H., Baumeister, W., Brunger, A.T., Morphologies of synaptic protein membrane fusion interfaces. Proc. Natl. Acad. Sci. USA, 2017, 10.1073/pnas.1708492114 Published online July 24, 2017.
-
(2017)
Proc. Natl. Acad. Sci. USA
-
-
Gipson, P.1
Fukuda, Y.2
Danev, R.3
Lai, Y.4
Chen, D.-H.5
Baumeister, W.6
Brunger, A.T.7
-
21
-
-
38949089701
-
Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes
-
Guan, R., Dai, H., Rizo, J., Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes. Biochemistry 47 (2008), 1474–1481.
-
(2008)
Biochemistry
, vol.47
, pp. 1474-1481
-
-
Guan, R.1
Dai, H.2
Rizo, J.3
-
22
-
-
34548263167
-
Open syntaxin docks synaptic vesicles
-
Hammarlund, M., Palfreyman, M.T., Watanabe, S., Olsen, S., Jorgensen, E.M., Open syntaxin docks synaptic vesicles. PLoS Biol., 5, 2007, e198.
-
(2007)
PLoS Biol.
, vol.5
, pp. e198
-
-
Hammarlund, M.1
Palfreyman, M.T.2
Watanabe, S.3
Olsen, S.4
Jorgensen, E.M.5
-
23
-
-
0028023444
-
Calcium dependence of the rate of exocytosis in a synaptic terminal
-
Heidelberger, R., Heinemann, C., Neher, E., Matthews, G., Calcium dependence of the rate of exocytosis in a synaptic terminal. Nature 371 (1994), 513–515.
-
(1994)
Nature
, vol.371
, pp. 513-515
-
-
Heidelberger, R.1
Heinemann, C.2
Neher, E.3
Matthews, G.4
-
24
-
-
84908246400
-
The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones
-
Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T.C., Rhee, J., Brose, N., Cooper, B.H., The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron 84 (2014), 416–431.
-
(2014)
Neuron
, vol.84
, pp. 416-431
-
-
Imig, C.1
Min, S.-W.2
Krinner, S.3
Arancillo, M.4
Rosenmund, C.5
Südhof, T.C.6
Rhee, J.7
Brose, N.8
Cooper, B.H.9
-
25
-
-
36049025863
-
CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins
-
Jockusch, W.J., Speidel, D., Sigler, A., Sørensen, J.B., Varoqueaux, F., Rhee, J.-S., Brose, N., CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell 131 (2007), 796–808.
-
(2007)
Cell
, vol.131
, pp. 796-808
-
-
Jockusch, W.J.1
Speidel, D.2
Sigler, A.3
Sørensen, J.B.4
Varoqueaux, F.5
Rhee, J.-S.6
Brose, N.7
-
26
-
-
4043075637
-
Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity
-
Junge, H.J., Rhee, J.S., Jahn, O., Varoqueaux, F., Spiess, J., Waxham, M.N., Rosenmund, C., Brose, N., Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity. Cell 118 (2004), 389–401.
-
(2004)
Cell
, vol.118
, pp. 389-401
-
-
Junge, H.J.1
Rhee, J.S.2
Jahn, O.3
Varoqueaux, F.4
Spiess, J.5
Waxham, M.N.6
Rosenmund, C.7
Brose, N.8
-
27
-
-
0021999794
-
Lipid composition of different areas of murine brain: effects of lipid extraction procedures
-
Katyal, S.L., Barilaro, L., Hanin, I., Lipid composition of different areas of murine brain: effects of lipid extraction procedures. Lipids 20 (1985), 201–203.
-
(1985)
Lipids
, vol.20
, pp. 201-203
-
-
Katyal, S.L.1
Barilaro, L.2
Hanin, I.3
-
28
-
-
0034235922
-
Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform
-
Koch, H., Hofmann, K., Brose, N., Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform. Biochem. J. 349 (2000), 247–253.
-
(2000)
Biochem. J.
, vol.349
, pp. 247-253
-
-
Koch, H.1
Hofmann, K.2
Brose, N.3
-
29
-
-
84872008490
-
Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system
-
Kyoung, M., Zhang, Y., Diao, J., Chu, S., Brunger, A.T., Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system. Nat. Protoc. 8 (2013), 1–16.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 1-16
-
-
Kyoung, M.1
Zhang, Y.2
Diao, J.3
Chu, S.4
Brunger, A.T.5
-
30
-
-
84921817984
-
Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms
-
Lai, Y., Diao, J., Cipriano, D.J., Zhang, Y., Pfuetzner, R.A., Padolina, M.S., Brunger, A.T., Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms. eLife, 3, 2014, e03756.
-
(2014)
eLife
, vol.3
, pp. e03756
-
-
Lai, Y.1
Diao, J.2
Cipriano, D.J.3
Zhang, Y.4
Pfuetzner, R.A.5
Padolina, M.S.6
Brunger, A.T.7
-
31
-
-
84982073759
-
N-terminal domain of complexin independently activates calcium-triggered fusion
-
Lai, Y., Choi, U.B., Zhang, Y., Zhao, M., Pfuetzner, R.A., Wang, A.L., Diao, J., Brunger, A.T., N-terminal domain of complexin independently activates calcium-triggered fusion. Proc. Natl. Acad. Sci. USA 113 (2016), E4698–E4707.
-
(2016)
Proc. Natl. Acad. Sci. USA
, vol.113
, pp. E4698-E4707
-
-
Lai, Y.1
Choi, U.B.2
Zhang, Y.3
Zhao, M.4
Pfuetzner, R.A.5
Wang, A.L.6
Diao, J.7
Brunger, A.T.8
-
32
-
-
84868688514
-
Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity
-
Lipstein, N., Schaks, S., Dimova, K., Kalkhof, S., Ihling, C., Kölbel, K., Ashery, U., Rhee, J., Brose, N., Sinz, A., Jahn, O., Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity. Mol. Cell. Biol. 32 (2012), 4628–4641.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4628-4641
-
-
Lipstein, N.1
Schaks, S.2
Dimova, K.3
Kalkhof, S.4
Ihling, C.5
Kölbel, K.6
Ashery, U.7
Rhee, J.8
Brose, N.9
Sinz, A.10
Jahn, O.11
-
33
-
-
84979666746
-
Functional synergy between the Munc13 C-terminal C1 and C2 domains
-
Liu, X., Seven, A.B., Camacho, M., Esser, V., Xu, J., Trimbuch, T., Quade, B., Su, L., Ma, C., Rosenmund, C., Rizo, J., Functional synergy between the Munc13 C-terminal C1 and C2 domains. eLife 5 (2016), 1–27.
-
(2016)
eLife
, vol.5
, pp. 1-27
-
-
Liu, X.1
Seven, A.B.2
Camacho, M.3
Esser, V.4
Xu, J.5
Trimbuch, T.6
Quade, B.7
Su, L.8
Ma, C.9
Rosenmund, C.10
Rizo, J.11
-
34
-
-
85027945821
-
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex
-
Ma, C., Li, W., Xu, Y., Rizo, J., Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nat. Struct. Mol. Biol. 18 (2011), 542–549.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 542-549
-
-
Ma, C.1
Li, W.2
Xu, Y.3
Rizo, J.4
-
35
-
-
84872802734
-
Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release
-
Ma, C., Su, L., Seven, A.B., Xu, Y., Rizo, J., Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release. Science 339 (2013), 421–425.
-
(2013)
Science
, vol.339
, pp. 421-425
-
-
Ma, C.1
Su, L.2
Seven, A.B.3
Xu, Y.4
Rizo, J.5
-
36
-
-
77955700423
-
Optimizing methods to recover absolute FRET efficiency from immobilized single molecules
-
McCann, J.J., Choi, U.B., Zheng, L., Weninger, K., Bowen, M.E., Optimizing methods to recover absolute FRET efficiency from immobilized single molecules. Biophys. J. 99 (2010), 961–970.
-
(2010)
Biophys. J.
, vol.99
, pp. 961-970
-
-
McCann, J.J.1
Choi, U.B.2
Zheng, L.3
Weninger, K.4
Bowen, M.E.5
-
37
-
-
0028880456
-
Complexins: cytosolic proteins that regulate SNAP receptor function
-
McMahon, H.T., Missler, M., Li, C., Südhof, T.C., Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83 (1995), 111–119.
-
(1995)
Cell
, vol.83
, pp. 111-119
-
-
McMahon, H.T.1
Missler, M.2
Li, C.3
Südhof, T.C.4
-
38
-
-
0034704771
-
Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
-
Misura, K.M., Scheller, R.H., Weis, W.I., Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex. Nature 404 (2000), 355–362.
-
(2000)
Nature
, vol.404
, pp. 355-362
-
-
Misura, K.M.1
Scheller, R.H.2
Weis, W.I.3
-
39
-
-
84945465967
-
Complexins: small but capable
-
Mohrmann, R., Dhara, M., Bruns, D., Complexins: small but capable. Cell. Mol. Life Sci. 72 (2015), 4221–4235.
-
(2015)
Cell. Mol. Life Sci.
, vol.72
, pp. 4221-4235
-
-
Mohrmann, R.1
Dhara, M.2
Bruns, D.3
-
40
-
-
0027932454
-
Specificity and regulation of a synaptic vesicle docking complex
-
Pevsner, J., Hsu, S.C., Braun, J.E., Calakos, N., Ting, A.E., Bennett, M.K., Scheller, R.H., Specificity and regulation of a synaptic vesicle docking complex. Neuron 13 (1994), 353–361.
-
(1994)
Neuron
, vol.13
, pp. 353-361
-
-
Pevsner, J.1
Hsu, S.C.2
Braun, J.E.3
Calakos, N.4
Ting, A.E.5
Bennett, M.K.6
Scheller, R.H.7
-
41
-
-
18244389735
-
Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs
-
Rhee, J.S., Betz, A., Pyott, S., Reim, K., Varoqueaux, F., Augustin, I., Hesse, D., Südhof, T.C., Takahashi, M., Rosenmund, C., Brose, N., Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs. Cell 108 (2002), 121–133.
-
(2002)
Cell
, vol.108
, pp. 121-133
-
-
Rhee, J.S.1
Betz, A.2
Pyott, S.3
Reim, K.4
Varoqueaux, F.5
Augustin, I.6
Hesse, D.7
Südhof, T.C.8
Takahashi, M.9
Rosenmund, C.10
Brose, N.11
-
42
-
-
0033349884
-
UNC-13 is required for synaptic vesicle fusion in C. elegans
-
Richmond, J.E., Davis, W.S., Jorgensen, E.M., UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat. Neurosci. 2 (1999), 959–964.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 959-964
-
-
Richmond, J.E.1
Davis, W.S.2
Jorgensen, E.M.3
-
43
-
-
0035913332
-
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
-
Richmond, J.E., Weimer, R.M., Jorgensen, E.M., An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412 (2001), 338–341.
-
(2001)
Nature
, vol.412
, pp. 338-341
-
-
Richmond, J.E.1
Weimer, R.M.2
Jorgensen, E.M.3
-
44
-
-
19544382047
-
Arachidonic acid allows SNARE complex formation in the presence of Munc18
-
Rickman, C., Davletov, B., Arachidonic acid allows SNARE complex formation in the presence of Munc18. Chem. Biol. 12 (2005), 545–553.
-
(2005)
Chem. Biol.
, vol.12
, pp. 545-553
-
-
Rickman, C.1
Davletov, B.2
-
45
-
-
0037204063
-
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms
-
Rosenmund, C., Sigler, A., Augustin, I., Reim, K., Brose, N., Rhee, J.-S., Differential control of vesicle priming and short-term plasticity by Munc13 isoforms. Neuron 33 (2002), 411–424.
-
(2002)
Neuron
, vol.33
, pp. 411-424
-
-
Rosenmund, C.1
Sigler, A.2
Augustin, I.3
Reim, K.4
Brose, N.5
Rhee, J.-S.6
-
46
-
-
84935457039
-
The principle of membrane fusion in the cell (Nobel lecture)
-
Rothman, J.E., The principle of membrane fusion in the cell (Nobel lecture). Angew. Chem. Int. Ed. Engl. 53 (2014), 12676–12694.
-
(2014)
Angew. Chem. Int. Ed. Engl.
, vol.53
, pp. 12676-12694
-
-
Rothman, J.E.1
-
47
-
-
0034710645
-
Intracellular calcium dependence of transmitter release rates at a fast central synapse
-
Schneggenburger, R., Neher, E., Intracellular calcium dependence of transmitter release rates at a fast central synapse. Nature 406 (2000), 889–893.
-
(2000)
Nature
, vol.406
, pp. 889-893
-
-
Schneggenburger, R.1
Neher, E.2
-
48
-
-
77949266565
-
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis
-
Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D.R., Pang, Z.P., Wojcik, S.M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol. 17 (2010), 280–288.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 280-288
-
-
Shin, O.-H.1
Lu, J.2
Rhee, J.-S.3
Tomchick, D.R.4
Pang, Z.P.5
Wojcik, S.M.6
Camacho-Perez, M.7
Brose, N.8
Machius, M.9
Rizo, J.10
-
49
-
-
29044435309
-
Identification of the minimal protein domain required for priming activity of Munc13-1
-
Stevens, D.R., Wu, Z.X., Matti, U., Junge, H.J., Schirra, C., Becherer, U., Wojcik, S.M., Brose, N., Rettig, J., Identification of the minimal protein domain required for priming activity of Munc13-1. Curr. Biol. 15 (2005), 2243–2248.
-
(2005)
Curr. Biol.
, vol.15
, pp. 2243-2248
-
-
Stevens, D.R.1
Wu, Z.X.2
Matti, U.3
Junge, H.J.4
Schirra, C.5
Becherer, U.6
Wojcik, S.M.7
Brose, N.8
Rettig, J.9
-
50
-
-
84863826404
-
The presynaptic active zone
-
Südhof, T.C., The presynaptic active zone. Neuron 75 (2012), 11–25.
-
(2012)
Neuron
, vol.75
, pp. 11-25
-
-
Südhof, T.C.1
-
51
-
-
84886998869
-
Neurotransmitter release: the last millisecond in the life of a synaptic vesicle
-
Südhof, T.C.C., Neurotransmitter release: the last millisecond in the life of a synaptic vesicle. Neuron 80 (2013), 675–690.
-
(2013)
Neuron
, vol.80
, pp. 675-690
-
-
Südhof, T.C.C.1
-
52
-
-
3543096759
-
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
-
Sutton, R.B., Fasshauer, D., Jahn, R., Brunger, A.T., Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature 395 (1998), 347–353.
-
(1998)
Nature
, vol.395
, pp. 347-353
-
-
Sutton, R.B.1
Fasshauer, D.2
Jahn, R.3
Brunger, A.T.4
-
53
-
-
84955558256
-
Should I stop or should I go? The role of complexin in neurotransmitter release
-
Trimbuch, T., Rosenmund, C., Should I stop or should I go? The role of complexin in neurotransmitter release. Nat. Rev. Neurosci. 17 (2016), 118–125.
-
(2016)
Nat. Rev. Neurosci.
, vol.17
, pp. 118-125
-
-
Trimbuch, T.1
Rosenmund, C.2
-
54
-
-
0037172972
-
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
-
Varoqueaux, F., Sigler, A., Rhee, J.-S., Brose, N., Enk, C., Reim, K., Rosenmund, C., Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc. Natl. Acad. Sci. USA 99 (2002), 9037–9042.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9037-9042
-
-
Varoqueaux, F.1
Sigler, A.2
Rhee, J.-S.3
Brose, N.4
Enk, C.5
Reim, K.6
Rosenmund, C.7
-
55
-
-
0034603030
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion
-
Verhage, M., Maia, A.S., Plomp, J.J., Brussaard, A.B., Heeroma, J.H., Vermeer, H., Toonen, R.F., Hammer, R.E., van den Berg, T.K., Missler, M., et al. Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287 (2000), 864–869.
-
(2000)
Science
, vol.287
, pp. 864-869
-
-
Verhage, M.1
Maia, A.S.2
Plomp, J.J.3
Brussaard, A.B.4
Heeroma, J.H.5
Vermeer, H.6
Toonen, R.F.7
Hammer, R.E.8
van den Berg, T.K.9
Missler, M.10
-
56
-
-
84991108519
-
Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking
-
Wang, S.S.H., Held, R.G., Wong, M.Y., Liu, C., Karakhanyan, A., Kaeser, P.S., Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking. Neuron 91 (2016), 777–791.
-
(2016)
Neuron
, vol.91
, pp. 777-791
-
-
Wang, S.S.H.1
Held, R.G.2
Wong, M.Y.3
Liu, C.4
Karakhanyan, A.5
Kaeser, P.S.6
-
57
-
-
85011271290
-
Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis
-
Wang, S., Choi, U.B., Gong, J., Yang, X., Li, Y., Wang, A.L., Yang, X., Brunger, A.T., Ma, C., Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis. EMBO J. 36 (2017), 816–829.
-
(2017)
EMBO J.
, vol.36
, pp. 816-829
-
-
Wang, S.1
Choi, U.B.2
Gong, J.3
Yang, X.4
Li, Y.5
Wang, A.L.6
Yang, X.7
Brunger, A.T.8
Ma, C.9
-
58
-
-
0032549708
-
SNAREpins: minimal machinery for membrane fusion
-
Weber, T., Zemelman, B.V., McNew, J.A., Westermann, B., Gmachl, M., Parlati, F., Söllner, T.H., Rothman, J.E., SNAREpins: minimal machinery for membrane fusion. Cell 92 (1998), 759–772.
-
(1998)
Cell
, vol.92
, pp. 759-772
-
-
Weber, T.1
Zemelman, B.V.2
McNew, J.A.3
Westermann, B.4
Gmachl, M.5
Parlati, F.6
Söllner, T.H.7
Rothman, J.E.8
-
59
-
-
0345166865
-
Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations
-
Weninger, K., Bowen, M.E., Chu, S., Brunger, A.T., Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations. Proc. Natl. Acad. Sci. USA 100 (2003), 14800–14805.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14800-14805
-
-
Weninger, K.1
Bowen, M.E.2
Chu, S.3
Brunger, A.T.4
-
60
-
-
38949211822
-
Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex
-
Weninger, K., Bowen, M.E., Choi, U.B., Chu, S., Brunger, A.T., Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex. Structure 16 (2008), 308–320.
-
(2008)
Structure
, vol.16
, pp. 308-320
-
-
Weninger, K.1
Bowen, M.E.2
Choi, U.B.3
Chu, S.4
Brunger, A.T.5
-
61
-
-
70450230360
-
A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly
-
Winter, U., Chen, X., Fasshauer, D., A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly. J. Biol. Chem. 284 (2009), 31817–31826.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31817-31826
-
-
Winter, U.1
Chen, X.2
Fasshauer, D.3
-
62
-
-
0033739633
-
The t-SNARE syntaxin is sufficient for spontaneous fusion of synaptic vesicles to planar membranes
-
Woodbury, D.J., Rognlien, K., The t-SNARE syntaxin is sufficient for spontaneous fusion of synaptic vesicles to planar membranes. Cell Biol. Int. 24 (2000), 809–818.
-
(2000)
Cell Biol. Int.
, vol.24
, pp. 809-818
-
-
Woodbury, D.J.1
Rognlien, K.2
-
63
-
-
67349106087
-
Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release
-
Xu, J., Pang, Z.P., Shin, O.-H., Südhof, T.C., Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release. Nat. Neurosci. 12 (2009), 759–766.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 759-766
-
-
Xu, J.1
Pang, Z.P.2
Shin, O.-H.3
Südhof, T.C.4
-
64
-
-
85014954043
-
Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
-
Xu, J., Camacho, M., Xu, Y., Esser, V., Liu, X., Trimbuch, T., Pan, Y.-Z., Ma, C., Tomchick, D.R., Rosenmund, C., Rizo, J., Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. eLife, 6, 2017, 10.7554/eLife.22567.
-
(2017)
eLife
, vol.6
-
-
Xu, J.1
Camacho, M.2
Xu, Y.3
Esser, V.4
Liu, X.5
Trimbuch, T.6
Pan, Y.-Z.7
Ma, C.8
Tomchick, D.R.9
Rosenmund, C.10
Rizo, J.11
-
65
-
-
0034707644
-
nSec1 binds a closed conformation of syntaxin1A
-
Yang, B., Steegmaier, M., Gonzalez, L.C. Jr., Scheller, R.H., nSec1 binds a closed conformation of syntaxin1A. J. Cell Biol. 148 (2000), 247–252.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 247-252
-
-
Yang, B.1
Steegmaier, M.2
Gonzalez, L.C.3
Scheller, R.H.4
-
66
-
-
84936764104
-
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
-
Yang, X., Wang, S., Sheng, Y., Zhang, M., Zou, W., Wu, L., Kang, L., Rizo, J., Zhang, R., Xu, T., Ma, C., Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming. Nat. Struct. Mol. Biol. 22 (2015), 547–554.
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 547-554
-
-
Yang, X.1
Wang, S.2
Sheng, Y.3
Zhang, M.4
Zou, W.5
Wu, L.6
Kang, L.7
Rizo, J.8
Zhang, R.9
Xu, T.10
Ma, C.11
-
67
-
-
84940928578
-
Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis
-
Zhou, Q., Lai, Y., Bacaj, T., Zhao, M., Lyubimov, A.Y., Uervirojnangkoorn, M., Zeldin, O.B., Brewster, A.S., Sauter, N.K., Cohen, A.E., et al. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature 525 (2015), 62–67.
-
(2015)
Nature
, vol.525
, pp. 62-67
-
-
Zhou, Q.1
Lai, Y.2
Bacaj, T.3
Zhao, M.4
Lyubimov, A.Y.5
Uervirojnangkoorn, M.6
Zeldin, O.B.7
Brewster, A.S.8
Sauter, N.K.9
Cohen, A.E.10
-
68
-
-
85026399649
-
The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis
-
Published online August 24, 2017
-
Zhou, Q., Zhou, P., Wang, A.L., Wu, D., Zhao, M., Südhof, T.C., Brunger, A.T., The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature, 2017, 10.1038/nature23484 Published online August 24, 2017.
-
(2017)
Nature
-
-
Zhou, Q.1
Zhou, P.2
Wang, A.L.3
Wu, D.4
Zhao, M.5
Südhof, T.C.6
Brunger, A.T.7
-
69
-
-
84920986272
-
A distinct tethering step is vital for vacuole membrane fusion
-
Zick, M., Wickner, W.T., A distinct tethering step is vital for vacuole membrane fusion. eLife, 3, 2014, e03251.
-
(2014)
eLife
, vol.3
, pp. e03251
-
-
Zick, M.1
Wickner, W.T.2
|