-
1
-
-
0033352861
-
Drosophila UNC-13 is essential for synaptic transmission
-
Aravamudan B, Fergestad T, Davis WS, Rodesch CK, Broadie K. 1999. Drosophila UNC-13 is essential for synaptic transmission. Nature Neuroscience 2:965-971. doi: 10.1038/14764
-
(1999)
Nature Neuroscience
, vol.2
, pp. 965-971
-
-
Aravamudan, B.1
Fergestad, T.2
Davis, W.S.3
Rodesch, C.K.4
Broadie, K.5
-
2
-
-
33644804207
-
Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids
-
Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. 2006. Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nature Structural & Molecular Biology 13:209-217. doi: 10.1038/nsmb1056
-
(2006)
Nature Structural & Molecular Biology
, vol.13
, pp. 209-217
-
-
Araç, D.1
Chen, X.2
Khant, H.A.3
Ubach, J.4
Ludtke, S.J.5
Kikkawa, M.6
Johnson, A.E.7
Chiu, W.8
Südhof, T.C.9
Rizo, J.10
-
3
-
-
0033615054
-
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
-
Augustin I, Rosenmund C, Südhof TC, Brose N. 1999. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature 400:457-461. doi: 10.1038/22768
-
(1999)
Nature
, vol.400
, pp. 457-461
-
-
Augustin, I.1
Rosenmund, C.2
Südhof, T.C.3
Brose, N.4
-
4
-
-
84946088224
-
Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles
-
Bacaj T, Wu D, Burré J, Malenka RC, Liu X, Südhof TC. 2015. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. PLoS Biology 13:e1002267. doi: 10.1371/journal.pbio.1002267
-
(2015)
PLoS Biology
, vol.13
-
-
Bacaj, T.1
Wu, D.2
Burré, J.3
Malenka, R.C.4
Liu, X.5
Südhof, T.C.6
-
5
-
-
0029808089
-
N-Ethylmaleimide-sensitive factor acts at a prefusion ATP-dependent step in Ca2+-activated exocytosis
-
Banerjee A, Barry VA, DasGupta BR, Martin TF. 1996. N-Ethylmaleimide-sensitive factor acts at a prefusion ATP-dependent step in Ca2+-activated exocytosis. The Journal of Biological Chemistry 271:20223-20226. doi: 10. 1074/jbc.271.34.20223
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 20223-20226
-
-
Banerjee, A.1
Barry, V.A.2
DasGupta, B.R.3
Martin, T.F.4
-
6
-
-
33846794400
-
Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion
-
Basu J, Betz A, Brose N, Rosenmund C. 2007. Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion. Journal of Neuroscience 27:1200-1210. doi: 10.1523/JNEUROSCI.4908-06.2007
-
(2007)
Journal of Neuroscience
, vol.27
, pp. 1200-1210
-
-
Basu, J.1
Betz, A.2
Brose, N.3
Rosenmund, C.4
-
7
-
-
33645014145
-
A minimal domain responsible for Munc13 activity
-
Basu J, Shen N, Dulubova I, Lu J, Guan R, Guryev O, Grishin NV, Rosenmund C, Rizo J. 2005. A minimal domain responsible for Munc13 activity. Nature Structural & Molecular Biology 12:1017-1018. doi: 10.1038/nsmb1001
-
(2005)
Nature Structural & Molecular Biology
, vol.12
, pp. 1017-1018
-
-
Basu, J.1
Shen, N.2
Dulubova, I.3
Lu, J.4
Guan, R.5
Guryev, O.6
Grishin, N.V.7
Rosenmund, C.8
Rizo, J.9
-
8
-
-
84861922902
-
Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
-
Boswell KL, James DJ, Esquibel JM, Bruinsma S, Shirakawa R, Horiuchi H, Martin TF. 2012. Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion. The Journal of Cell Biology 197:301-312. doi: 10.1083/jcb.201109132
-
(2012)
The Journal of Cell Biology
, vol.197
, pp. 301-312
-
-
Boswell, K.L.1
James, D.J.2
Esquibel, J.M.3
Bruinsma, S.4
Shirakawa, R.5
Horiuchi, H.6
Martin, T.F.7
-
9
-
-
84936742157
-
Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
-
Brewer KD, Bacaj T, Cavalli A, Camilloni C, Swarbrick JD, Liu J, Zhou A, Zhou P, Barlow N, Xu J, Seven AB, Prinslow EA, Voleti R, Häussinger D, Bonvin AM, Tomchick DR, Vendruscolo M, Graham B, Südhof TC, Rizo J. 2015. Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nature Structural & Molecular Biology 22:555-564. doi: 10.1038/nsmb.3035
-
(2015)
Nature Structural & Molecular Biology
, vol.22
, pp. 555-564
-
-
Brewer, K.D.1
Bacaj, T.2
Cavalli, A.3
Camilloni, C.4
Swarbrick, J.D.5
Liu, J.6
Zhou, A.7
Zhou, P.8
Barlow, N.9
Xu, J.10
Seven, A.B.11
Prinslow, E.A.12
Voleti, R.13
Häussinger, D.14
Bonvin, A.M.15
Tomchick, D.R.16
Vendruscolo, M.17
Graham, B.18
Südhof, T.C.19
Rizo, J.20
more..
-
10
-
-
0028791349
-
Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins
-
Brose N, Hofmann K, Hata Y, Südhof TC. 1995. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. The Journal of Biological Chemistry 270:25273-25280. doi: 10. 1074/jbc.270.42.25273
-
(1995)
The Journal of Biological Chemistry
, vol.270
, pp. 25273-25280
-
-
Brose, N.1
Hofmann, K.2
Hata, Y.3
Südhof, T.C.4
-
13
-
-
33646007069
-
SNARE-mediated lipid mixing depends on the physical state of the vesicles
-
Chen X, Araç D, Wang TM, Gilpin CJ, Zimmerberg J, Rizo J. 2006. SNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophysical Journal 90:2062-2074. doi: 10.1529/biophysj.105.071415
-
(2006)
Biophysical Journal
, vol.90
, pp. 2062-2074
-
-
Chen, X.1
Araç, D.2
Wang, T.M.3
Gilpin, C.J.4
Zimmerberg, J.5
Rizo, J.6
-
14
-
-
0037204076
-
Three-dimensional structure of the complexin/SNARE complex
-
Chen X, Tomchick DR, Kovrigin E, Araç D, Machius M, Südhof TC, Rizo J. 2002. Three-dimensional structure of the complexin/SNARE complex. Neuron 33:397-409. doi: 10.1016/S0896-6273(02)00583-4
-
(2002)
Neuron
, vol.33
, pp. 397-409
-
-
Chen, X.1
Tomchick, D.R.2
Kovrigin, E.3
Araç, D.4
Machius, M.5
Südhof, T.C.6
Rizo, J.7
-
15
-
-
84881514823
-
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
-
Diao J, Grob P, Cipriano DJ, Kyoung M, Zhang Y, Shah S, Nguyen A, Padolina M, Srivastava A, Vrljic M, Shah A, Nogales E, Chu S, Brunger AT. 2012. Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. eLife 1:e00109. doi: 10.7554/eLife.00109
-
(2012)
eLife
, vol.1
-
-
Diao, J.1
Grob, P.2
Cipriano, D.J.3
Kyoung, M.4
Zhang, Y.5
Shah, S.6
Nguyen, A.7
Padolina, M.8
Srivastava, A.9
Vrljic, M.10
Shah, A.11
Nogales, E.12
Chu, S.13
Brunger, A.T.14
-
16
-
-
33847326814
-
Munc18-1 binds directly to the neuronal SNARE complex
-
Dulubova I, Khvotchev M, Liu S, Huryeva I, Südhof TC, Rizo J. 2007. Munc18-1 binds directly to the neuronal SNARE complex. Proceedings of the National Academy of Sciences of the United States of America 104:2697-2702. doi: 10.1073/pnas.0611318104
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 2697-2702
-
-
Dulubova, I.1
Khvotchev, M.2
Liu, S.3
Huryeva, I.4
Südhof, T.C.5
Rizo, J.6
-
17
-
-
28844449520
-
A Munc13/RIM/Rab3 tripartite complex: From priming to plasticity?
-
Dulubova I, Lou X, Lu J, Huryeva I, Alam A, Schneggenburger R, Südhof TC, Rizo J. 2005. A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? The EMBO Journal 24:2839-2850. doi: 10.1038/sj.emboj. 7600753
-
(2005)
The EMBO Journal
, vol.24
, pp. 2839-2850
-
-
Dulubova, I.1
Lou, X.2
Lu, J.3
Huryeva, I.4
Alam, A.5
Schneggenburger, R.6
Südhof, T.C.7
Rizo, J.8
-
18
-
-
0033575749
-
A conformational switch in syntaxin during exocytosis: Role of munc18
-
Dulubova I, Sugita S, Hill S, Hosaka M, Fernandez I, Südhof TC, Rizo J. 1999. A conformational switch in syntaxin during exocytosis: role of munc18. The EMBO Journal 18:4372-4382. doi: 10.1093/emboj/18.16.4372
-
(1999)
The EMBO Journal
, vol.18
, pp. 4372-4382
-
-
Dulubova, I.1
Sugita, S.2
Hill, S.3
Hosaka, M.4
Fernandez, I.5
Südhof, T.C.6
Rizo, J.7
-
19
-
-
0035282457
-
Synaptotagmin I functions as a calcium regulator of release probability
-
Fernández-Chacón R, Königstorfer A, Gerber SH, García J, Matos MF, Stevens CF, Brose N, Rizo J, Rosenmund C, Südhof TC. 2001. Synaptotagmin I functions as a calcium regulator of release probability. Nature 410:41-49. doi: 10.1038/35065004
-
(2001)
Nature
, vol.410
, pp. 41-49
-
-
Fernández-Chacón, R.1
Königstorfer, A.2
Gerber, S.H.3
García, J.4
Matos, M.F.5
Stevens, C.F.6
Brose, N.7
Rizo, J.8
Rosenmund, C.9
Südhof, T.C.10
-
20
-
-
0028061861
-
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
-
Geppert M, Goda Y, Hammer RE, Li C, Rosahl TW, Stevens CF, Südhof TC. 1994. Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell 79:717-727. doi: 10.1016/0092-8674(94)90556-8
-
(1994)
Cell
, vol.79
, pp. 717-727
-
-
Geppert, M.1
Goda, Y.2
Hammer, R.E.3
Li, C.4
Rosahl, T.W.5
Stevens, C.F.6
Südhof, T.C.7
-
22
-
-
38949089701
-
Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes
-
Guan R, Dai H, Rizo J. 2008. Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes. Biochemistry 47:1474-1481. doi: 10.1021/bi702345m
-
(2008)
Biochemistry
, vol.47
, pp. 1474-1481
-
-
Guan, R.1
Dai, H.2
Rizo, J.3
-
23
-
-
34548263167
-
Open syntaxin docks synaptic vesicles
-
Hammarlund M, Palfreyman MT, Watanabe S, Olsen S, Jorgensen EM. 2007. Open syntaxin docks synaptic vesicles. PLoS Biology 5:e198. doi: 10.1371/journal.pbio.0050198
-
(2007)
PLoS Biology
, vol.5
-
-
Hammarlund, M.1
Palfreyman, M.T.2
Watanabe, S.3
Olsen, S.4
Jorgensen, E.M.5
-
24
-
-
0030740252
-
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy
-
Hanson PI, Roth R, Morisaki H, Jahn R, Heuser JE. 1997. Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90:523-535. doi: 10.1016/S0092-8674(00)80512-7
-
(1997)
Cell
, vol.90
, pp. 523-535
-
-
Hanson, P.I.1
Roth, R.2
Morisaki, H.3
Jahn, R.4
Heuser, J.E.5
-
25
-
-
84908246400
-
The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones
-
Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. 2014. The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron 84:416-431. doi: 10.1016/j.neuron.2014.10.009
-
(2014)
Neuron
, vol.84
, pp. 416-431
-
-
Imig, C.1
Min, S.W.2
Krinner, S.3
Arancillo, M.4
Rosenmund, C.5
Südhof, T.C.6
Rhee, J.7
Brose, N.8
Cooper, B.H.9
-
26
-
-
84867295592
-
Molecular machines governing exocytosis of synaptic vesicles
-
Jahn R, Fasshauer D. 2012. Molecular machines governing exocytosis of synaptic vesicles. Nature 490:201-207. doi: 10.1038/nature11320
-
(2012)
Nature
, vol.490
, pp. 201-207
-
-
Jahn, R.1
Fasshauer, D.2
-
27
-
-
79955707349
-
High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice
-
Kim JH, Lee SR, Li LH, Park HJ, Park JH, Lee KY, Kim MK, Shin BA, Choi SY. 2011. High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice. PloS One 6:e18556. doi:10.1371/journal.pone.0018556
-
(2011)
PloS One
, vol.6
-
-
Kim, J.H.1
Lee, S.R.2
Li, L.H.3
Park, H.J.4
Park, J.H.5
Lee, K.Y.6
Kim, M.K.7
Shin, B.A.8
Choi, S.Y.9
-
28
-
-
79961082568
-
In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
-
Kyoung M, Srivastava A, Zhang Y, Diao J, Vrljic M, Grob P, Nogales E, Chu S, Brunger AT. 2011. In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America 108. doi: 10.1073/pnas.1107900108
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, pp. 108
-
-
Kyoung, M.1
Srivastava, A.2
Zhang, Y.3
Diao, J.4
Vrljic, M.5
Grob, P.6
Nogales, E.7
Chu, S.8
Brunger, A.T.9
-
29
-
-
84921817984
-
Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms
-
Lai Y, Diao J, Cipriano DJ, Zhang Y, Pfuetzner RA, Padolina MS, Brunger AT. 2014. Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms. eLife 3:e03756. doi: 10.7554/eLife.03756
-
(2014)
eLife
, vol.3
-
-
Lai, Y.1
Diao, J.2
Cipriano, D.J.3
Zhang, Y.4
Pfuetzner, R.A.5
Padolina, M.S.6
Brunger, A.T.7
-
30
-
-
77952231768
-
Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1
-
Lee HK, Yang Y, Su Z, Hyeon C, Lee TS, Lee HW, Kweon DH, Shin YK, Yoon TY. 2010. Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1. Science 328:760-763. doi: 10.1126/science.1187722
-
(2010)
Science
, vol.328
, pp. 760-763
-
-
Lee, H.K.1
Yang, Y.2
Su, Z.3
Hyeon, C.4
Lee, T.S.5
Lee, H.W.6
Kweon, D.H.7
Shin, Y.K.8
Yoon, T.Y.9
-
31
-
-
80054056038
-
The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors
-
Li W, Ma C, Guan R, Xu Y, Tomchick DR, Rizo J. 2011. The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors. Structure 19:1443-1455. doi: 10.1016/j.str.2011.07. 012
-
(2011)
Structure
, vol.19
, pp. 1443-1455
-
-
Li, W.1
Ma, C.2
Guan, R.3
Xu, Y.4
Tomchick, D.R.5
Rizo, J.6
-
32
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295:868-872. doi: 10.1126/science.1067081
-
(2002)
Science
, vol.295
, pp. 868-872
-
-
Lois, C.1
Hong, E.J.2
Pease, S.3
Brown, E.J.4
Baltimore, D.5
-
33
-
-
85027945821
-
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex
-
Ma C, Li W, Xu Y, Rizo J. 2011. Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nature Structural & Molecular Biology 18:542-549. doi: 10.1038/nsmb.2047
-
(2011)
Nature Structural & Molecular Biology
, vol.18
, pp. 542-549
-
-
Ma, C.1
Li, W.2
Xu, Y.3
Rizo, J.4
-
34
-
-
84872802734
-
Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release
-
Ma C, Su L, Seven AB, Xu Y, Rizo J. 2013. Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release. Science 339:421-425. doi: 10.1126/science.1230473
-
(2013)
Science
, vol.339
, pp. 421-425
-
-
Ma, C.1
Su, L.2
Seven, A.B.3
Xu, Y.4
Rizo, J.5
-
35
-
-
29044447583
-
UNC-13 interaction with syntaxin is required for synaptic transmission
-
Madison JM, Nurrish S, Kaplan JM. 2005. UNC-13 interaction with syntaxin is required for synaptic transmission. Current Biology 15:2236-2242. doi: 10.1016/j.cub.2005.10.049
-
(2005)
Current Biology
, vol.15
, pp. 2236-2242
-
-
Madison, J.M.1
Nurrish, S.2
Kaplan, J.M.3
-
36
-
-
0037157825
-
Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I
-
Mahal LK, Sequeira SM, Gureasko JM, Söllner TH. 2002. Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I. The Journal of Cell Biology 158:273-282. doi: 10.1083/jcb.200203135
-
(2002)
The Journal of Cell Biology
, vol.158
, pp. 273-282
-
-
Mahal, L.K.1
Sequeira, S.M.2
Gureasko, J.M.3
Söllner, T.H.4
-
37
-
-
0029980441
-
Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles
-
Mayer A, Wickner W, Haas A. 1996. Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85:83-94. doi: 10.1016/S0092-8674(00)81084-3
-
(1996)
Cell
, vol.85
, pp. 83-94
-
-
Mayer, A.1
Wickner, W.2
Haas, A.3
-
38
-
-
0034704771
-
Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
-
Misura KM, Scheller RH, Weis WI. 2000. Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex. Nature 404:355-362. doi: 10.1038/35006120
-
(2000)
Nature
, vol.404
, pp. 355-362
-
-
Misura, K.M.1
Scheller, R.H.2
Weis, W.I.3
-
39
-
-
84866093345
-
SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1
-
Parisotto D, Malsam J, Scheutzow A, Krause JM, Söllner TH. 2012. SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1. The Journal of Biological Chemistry 287:31041-31049. doi: 10. 1074/jbc.M112.386805
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 31041-31049
-
-
Parisotto, D.1
Malsam, J.2
Scheutzow, A.3
Krause, J.M.4
Söllner, T.H.5
-
40
-
-
67651160303
-
Remote homology between Munc13 MUN domain and vesicle tethering complexes
-
Pei J, Ma C, Rizo J, Grishin NV. 2009. Remote homology between Munc13 MUN domain and vesicle tethering complexes. Journal of Molecular Biology 391:509-517. doi: 10.1016/j.jmb.2009.06.054
-
(2009)
Journal of Molecular Biology
, vol.391
, pp. 509-517
-
-
Pei, J.1
Ma, C.2
Rizo, J.3
Grishin, N.V.4
-
41
-
-
0031668972
-
The synaptic SNARE complex is a parallel four-stranded helical bundle
-
Poirier MA, Xiao W, Macosko JC, Chan C, Shin YK, Bennett MK. 1998. The synaptic SNARE complex is a parallel four-stranded helical bundle. Nature Structural Biology 5:765-769. doi: 10.1038/1799
-
(1998)
Nature Structural Biology
, vol.5
, pp. 765-769
-
-
Poirier, M.A.1
Xiao, W.2
Macosko, J.C.3
Chan, C.4
Shin, Y.K.5
Bennett, M.K.6
-
42
-
-
18244389735
-
Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs
-
Rhee JS, Betz A, Pyott S, Reim K, Varoqueaux F, Augustin I, Hesse D, Südhof TC, Takahashi M, Rosenmund C, Brose N. 2002. Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs. Cell 108:121-133. doi: 10.1016/S0092-8674(01)00635-3
-
(2002)
Cell
, vol.108
, pp. 121-133
-
-
Rhee, J.S.1
Betz, A.2
Pyott, S.3
Reim, K.4
Varoqueaux, F.5
Augustin, I.6
Hesse, D.7
Südhof, T.C.8
Takahashi, M.9
Rosenmund, C.10
Brose, N.11
-
43
-
-
0033349884
-
UNC-13 is required for synaptic vesicle fusion in C. elegans
-
Richmond JE, Davis WS, Jorgensen EM. 1999. UNC-13 is required for synaptic vesicle fusion in C. elegans. Nature Neuroscience 2:959-964. doi: 10.1038/14755
-
(1999)
Nature Neuroscience
, vol.2
, pp. 959-964
-
-
Richmond, J.E.1
Davis, W.S.2
Jorgensen, E.M.3
-
44
-
-
0035913332
-
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
-
Richmond JE, Weimer RM, Jorgensen EM. 2001. An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412:338-341. doi: 10.1038/35085583
-
(2001)
Nature
, vol.412
, pp. 338-341
-
-
Richmond, J.E.1
Weimer, R.M.2
Jorgensen, E.M.3
-
45
-
-
84870232182
-
The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices-guilty as charged?
-
Rizo J, Südhof TC. 2012. The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices-guilty as charged? Annual Review of Cell and Developmental Biology 28:279-308. doi: 10.1146/annurev-cellbio-101011-155818
-
(2012)
Annual Review of Cell and Developmental Biology
, vol.28
, pp. 279-308
-
-
Rizo, J.1
Südhof, T.C.2
-
46
-
-
0032568662
-
C2-domains, structure and function of a universal Ca2+-binding domain
-
Rizo J, Südhof TC. 1998. C2-domains, structure and function of a universal Ca2+-binding domain. The Journal of Biological Chemistry 273:15879-15882. doi: 10.1074/jbc.273.26.15879
-
(1998)
The Journal of Biological Chemistry
, vol.273
, pp. 15879-15882
-
-
Rizo, J.1
Südhof, T.C.2
-
47
-
-
84937394649
-
The synaptic vesicle release machinery
-
Rizo J, Xu J. 2015. The synaptic vesicle release machinery. Annual Review of Biophysics 44:339-367. doi: 10. 1146/annurev-biophys-060414-034057
-
(2015)
Annual Review of Biophysics
, vol.44
, pp. 339-367
-
-
Rizo, J.1
Xu, J.2
-
48
-
-
0037204063
-
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms
-
Rosenmund C, Sigler A, Augustin I, Reim K, Brose N, Rhee JS. 2002. Differential control of vesicle priming and short-term plasticity by Munc13 isoforms. Neuron 33:411-424. doi: 10.1016/S0896-6273(02)00568-8
-
(2002)
Neuron
, vol.33
, pp. 411-424
-
-
Rosenmund, C.1
Sigler, A.2
Augustin, I.3
Reim, K.4
Brose, N.5
Rhee, J.S.6
-
49
-
-
0030175394
-
Definition of the readily releasable pool of vesicles at hippocampal synapses
-
Rosenmund C, Stevens CF. 1996. Definition of the readily releasable pool of vesicles at hippocampal synapses. Neuron 16:1197-1207. doi: 10.1016/S0896-6273(00)80146-4
-
(1996)
Neuron
, vol.16
, pp. 1197-1207
-
-
Rosenmund, C.1
Stevens, C.F.2
-
50
-
-
33845987734
-
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins
-
Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ. 2007. Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell 128:183-195. doi: 10.1016/j.cell.2006.12.016
-
(2007)
Cell
, vol.128
, pp. 183-195
-
-
Shen, J.1
Tareste, D.C.2
Paumet, F.3
Rothman, J.E.4
Melia, T.J.5
-
51
-
-
13444259396
-
Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1
-
Shen N, Guryev O, Rizo J. 2005. Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1. Biochemistry 44:1089-1096. doi: 10.1021/bi0476127
-
(2005)
Biochemistry
, vol.44
, pp. 1089-1096
-
-
Shen, N.1
Guryev, O.2
Rizo, J.3
-
52
-
-
77949266565
-
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis
-
Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund C, Südhof TC. 2010. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nature Structural & Molecular Biology 17:280-288. doi: 10.1038/nsmb.1758
-
(2010)
Nature Structural & Molecular Biology
, vol.17
, pp. 280-288
-
-
Shin, O.H.1
Lu, J.2
Rhee, J.S.3
Tomchick, D.R.4
Pang, Z.P.5
Wojcik, S.M.6
Camacho-Perez, M.7
Brose, N.8
Machius, M.9
Rizo, J.10
Rosenmund, C.11
Südhof, T.C.12
-
53
-
-
34948827535
-
Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids
-
Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. 2007. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structural & Molecular Biology 14:904-911. doi: 10.1038/nsmb1305
-
(2007)
Nature Structural & Molecular Biology
, vol.14
, pp. 904-911
-
-
Stein, A.1
Radhakrishnan, A.2
Riedel, D.3
Fasshauer, D.4
Jahn, R.5
-
54
-
-
29044435309
-
Identification of the minimal protein domain required for priming activity of Munc13-1
-
Stevens DR, Wu ZX, Matti U, Junge HJ, Schirra C, Becherer U, Wojcik SM, Brose N, Rettig J. 2005. Identification of the minimal protein domain required for priming activity of Munc13-1. Current Biology 15:2243-2248. doi:10.1016/j.cub.2005.10.055
-
(2005)
Current Biology
, vol.15
, pp. 2243-2248
-
-
Stevens, D.R.1
Wu, Z.X.2
Matti, U.3
Junge, H.J.4
Schirra, C.5
Becherer, U.6
Wojcik, S.M.7
Brose, N.8
Rettig, J.9
-
55
-
-
3543096759
-
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
-
Sutton RB, Fasshauer D, Jahn R, Brunger AT. 1998. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature 395:347-353. doi: 10.1038/26412
-
(1998)
Nature
, vol.395
, pp. 347-353
-
-
Sutton, R.B.1
Fasshauer, D.2
Jahn, R.3
Brunger, A.T.4
-
56
-
-
0027517462
-
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
-
Söllner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE. 1993. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75:409-418. doi: 10.1016/0092-8674(93)90376-2
-
(1993)
Cell
, vol.75
, pp. 409-418
-
-
Söllner, T.1
Bennett, M.K.2
Whiteheart, S.W.3
Scheller, R.H.4
Rothman, J.E.5
-
57
-
-
58849092285
-
Membrane fusion: Grappling with SNARE and SM proteins
-
Südhof TC, Rothman JE. 2009. Membrane fusion: grappling with SNARE and SM proteins. Science 323:474-477. doi: 10.1126/science.1161748
-
(2009)
Science
, vol.323
, pp. 474-477
-
-
Südhof, T.C.1
Rothman, J.E.2
-
58
-
-
84886998869
-
Neurotransmitter release: The last millisecond in the life of a synaptic vesicle
-
Südhof TC. 2013. Neurotransmitter release: the last millisecond in the life of a synaptic vesicle. Neuron 80:675-690. doi: 10.1016/j.neuron.2013.10.022
-
(2013)
Neuron
, vol.80
, pp. 675-690
-
-
Südhof, T.C.1
-
59
-
-
1942520207
-
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs
-
Tucker WC, Weber T, Chapman ER. 2004. Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs. Science 304:435-438. doi: 10.1126/science.1097196
-
(2004)
Science
, vol.304
, pp. 435-438
-
-
Tucker, W.C.1
Weber, T.2
Chapman, E.R.3
-
60
-
-
77949268363
-
One SNARE complex is sufficient for membrane fusion
-
van den Bogaart G, Holt MG, Bunt G, Riedel D, Wouters FS, Jahn R. 2010. One SNARE complex is sufficient for membrane fusion. Nature Structural & Molecular Biology 17:358-364. doi: 10.1038/nsmb.1748
-
(2010)
Nature Structural & Molecular Biology
, vol.17
, pp. 358-364
-
-
van den Bogaart, G.1
Holt, M.G.2
Bunt, G.3
Riedel, D.4
Wouters, F.S.5
Jahn, R.6
-
61
-
-
0037172972
-
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
-
Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C. 2002. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences of the United States of America 99:9037-9042. doi: 10.1073/pnas.122623799
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 9037-9042
-
-
Varoqueaux, F.1
Sigler, A.2
Rhee, J.S.3
Brose, N.4
Enk, C.5
Reim, K.6
Rosenmund, C.7
-
62
-
-
0034603030
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion
-
Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Südhof TC. 2000. Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287:864-869. doi: 10.1126/science.287.5454.864
-
(2000)
Science
, vol.287
, pp. 864-869
-
-
Verhage, M.1
Maia, A.S.2
Plomp, J.J.3
Brussaard, A.B.4
Heeroma, J.H.5
Vermeer, H.6
Toonen, R.F.7
Hammer, R.E.8
van den Berg, T.K.9
Missler, M.10
Geuze, H.J.11
Südhof, T.C.12
-
63
-
-
0034729298
-
SNAREpins are functionally resistant to disruption by NSF and alphaSNAP
-
Weber T, Parlati F, McNew JA, Johnston RJ, Westermann B, Söllner TH, Rothman JE. 2000. SNAREpins are functionally resistant to disruption by NSF and alphaSNAP. The Journal of Cell Biology 149:1063-1072. doi: 10. 1083/jcb.149.5.1063
-
(2000)
The Journal of Cell Biology
, vol.149
, pp. 1063-1072
-
-
Weber, T.1
Parlati, F.2
McNew, J.A.3
Johnston, R.J.4
Westermann, B.5
Söllner, T.H.6
Rothman, J.E.7
-
64
-
-
0032549708
-
SNAREpins: Minimal machinery for membrane fusion
-
Weber T, Zemelman BV, McNew JA, Westermann B, Gmachl M, Parlati F, Söllner TH, Rothman JE. 1998. SNAREpins: minimal machinery for membrane fusion. Cell 92:759-772. doi: 10.1016/S0092-8674(00)81404-X
-
(1998)
Cell
, vol.92
, pp. 759-772
-
-
Weber, T.1
Zemelman, B.V.2
McNew, J.A.3
Westermann, B.4
Gmachl, M.5
Parlati, F.6
Söllner, T.H.7
Rothman, J.E.8
-
65
-
-
33748129499
-
UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains
-
Weimer RM, Gracheva EO, Meyrignac O, Miller KG, Richmond JE, Bessereau JL. 2006. UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains. Journal of Neuroscience 26:8040-8047. doi: 10.1523/JNEUROSCI.2350-06.2006
-
(2006)
Journal of Neuroscience
, vol.26
, pp. 8040-8047
-
-
Weimer, R.M.1
Gracheva, E.O.2
Meyrignac, O.3
Miller, K.G.4
Richmond, J.E.5
Bessereau, J.L.6
-
66
-
-
77953608974
-
HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion
-
Xu H, Jun Y, Thompson J, Yates J, Wickner W. 2010. HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion. The EMBO Journal 29:1948-1960. doi: 10.1038/emboj.2010.97
-
(2010)
The EMBO Journal
, vol.29
, pp. 1948-1960
-
-
Xu, H.1
Jun, Y.2
Thompson, J.3
Yates, J.4
Wickner, W.5
-
67
-
-
84883308384
-
Subtle Interplay between synaptotagmin and complexin binding to the SNARE complex
-
Xu J, Brewer KD, Perez-Castillejos R, Rizo J. 2013. Subtle Interplay between synaptotagmin and complexin binding to the SNARE complex. Journal of Molecular Biology 425:3461-3475. doi: 10.1016/j.jmb.2013.07.001
-
(2013)
Journal of Molecular Biology
, vol.425
, pp. 3461-3475
-
-
Xu, J.1
Brewer, K.D.2
Perez-Castillejos, R.3
Rizo, J.4
-
68
-
-
55549100557
-
The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function
-
Xue M, Ma C, Craig TK, Rosenmund C, Rizo J. 2008. The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function. Nature Structural & Molecular Biology 15:1160-1168. doi: 10.1038/nsmb.1508
-
(2008)
Nature Structural & Molecular Biology
, vol.15
, pp. 1160-1168
-
-
Xue, M.1
Ma, C.2
Craig, T.K.3
Rosenmund, C.4
Rizo, J.5
-
69
-
-
84936764104
-
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
-
Yang X, Wang S, Sheng Y, Zhang M, Zou W, Wu L, Kang L, Rizo J, Zhang R, Xu T, Ma C. 2015. Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming. Nature Structural & Molecular Biology 22:547-554. doi: 10.1038/nsmb.3038
-
(2015)
Nature Structural & Molecular Biology
, vol.22
, pp. 547-554
-
-
Yang, X.1
Wang, S.2
Sheng, Y.3
Zhang, M.4
Zou, W.5
Wu, L.6
Kang, L.7
Rizo, J.8
Zhang, R.9
Xu, T.10
Ma, C.11
-
70
-
-
84883339791
-
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
-
Yu H, Rathore SS, Lopez JA, Davis EM, James DE, Martin JL, Shen J. 2013. Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins. Proceedings of the National Academy of Sciences of the United States of America 110:E3271-E3280. doi: 10.1073/pnas.1311232110
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, pp. E3271-E3280
-
-
Yu, H.1
Rathore, S.S.2
Lopez, J.A.3
Davis, E.M.4
James, D.E.5
Martin, J.L.6
Shen, J.7
-
71
-
-
78049368534
-
Tethering factors as organizers of intracellular vesicular traffic
-
Yu IM, Hughson FM. 2010. Tethering factors as organizers of intracellular vesicular traffic. Annual Review of Cell and Developmental Biology 26:137-156. doi: 10.1146/annurev.cellbio.042308.113327
-
(2010)
Annual Review of Cell and Developmental Biology
, vol.26
, pp. 137-156
-
-
Yu, I.M.1
Hughson, F.M.2
-
72
-
-
84940928578
-
Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis
-
Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Sauter NK, Cohen AE, Soltis SM, Alonso-Mori R, Chollet M, Lemke HT, Pfuetzner RA, Choi UB, Weis WI, Diao J, Südhof TC, Brunger AT. 2015. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature 525:62-67. doi: 10.1038/nature14975
-
(2015)
Nature
, vol.525
, pp. 62-67
-
-
Zhou, Q.1
Lai, Y.2
Bacaj, T.3
Zhao, M.4
Lyubimov, A.Y.5
Uervirojnangkoorn, M.6
Zeldin, O.B.7
Brewster, A.S.8
Sauter, N.K.9
Cohen, A.E.10
Soltis, S.M.11
Alonso-Mori, R.12
Chollet, M.13
Lemke, H.T.14
Pfuetzner, R.A.15
Choi, U.B.16
Weis, W.I.17
Diao, J.18
Südhof, T.C.19
Brunger, A.T.20
more..
-
73
-
-
84928905805
-
Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18
-
Zick M, Orr A, Schwartz ML, Merz AJ, Wickner WT. 2015. Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18. Proceedings of the National Academy of Sciences of the United States of America 112:E2290-E2297. doi: 10.1073/pnas.1506409112
-
(2015)
Proceedings of the National Academy of Sciences of the United States of America
, vol.112
, pp. E2290-E2297
-
-
Zick, M.1
Orr, A.2
Schwartz, M.L.3
Merz, A.J.4
Wickner, W.T.5
-
74
-
-
84920986272
-
A distinct tethering step is vital for vacuole membrane fusion
-
Zick M, Wickner WT. 2014. A distinct tethering step is vital for vacuole membrane fusion. eLife 3:e03251. doi: 10. 7554/eLife.03251
-
(2014)
eLife
, vol.3
-
-
Zick, M.1
Wickner, W.T.2
-
75
-
-
80054793989
-
Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis
-
Zucchi PC, Zick M. 2011. Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis. Molecular Biology of the Cell 22:4635-4646. doi: 10. 1091/mbc.E11-08-0680
-
(2011)
Molecular Biology of the Cell
, vol.22
, pp. 4635-4646
-
-
Zucchi, P.C.1
Zick, M.2
|