Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN

eLife

Volumn 6, Issue , 2017, Pages

  Xu, Junjie ^a,b   Camacho, Marcial ^c   Xu, Yibin ^a,b   Esser, Victoria ^a,b   Liu, Xiaoxia ^a,b   Trimbuch, Thorsten ^c   Pan, Yun Zu ^a,b   Ma, Cong ^d   Tomchick, Diana R ^a,b   Rosenmund, Christian ^c   Rizo, Josep ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MUNC13 1 PROTEIN; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; NERVE PROTEIN; UNC13A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; GEL FILTRATION CHROMATOGRAPHY; GENE MUTATION; ION TRANSPORT; MOLECULAR CLONING; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROTRANSMITTER RELEASE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURAL PROTEOMICS; SYNAPTIC TRANSMISSION; WESTERN BLOTTING; X RAY DIFFRACTION; ANIMAL; CELL CULTURE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; NERVE CELL; PHYSIOLOGY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CELLS, CULTURED; CRYSTALLOGRAPHY, X-RAY; MICE; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; NEURONS; NEUROTRANSMITTER AGENTS; PROTEIN CONFORMATION; RATS;

EID: 85014954043     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.22567     Document Type: Article

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