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Volumn 232, Issue 11, 2017, Pages 2957-2963

Osteoblast role in osteoarthritis pathogenesis

Author keywords

bone; osteoarthritis; osteoblast

Indexed keywords

BETA CATENIN; ENDOTHELIN 1; EPHRIN; GROWTH FACTOR; PROTEINASE; VASCULOTROPIN; WNT PROTEIN;

EID: 85026304384     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25969     Document Type: Review
Times cited : (116)

References (79)
  • 2
    • 84887528105 scopus 로고    scopus 로고
    • Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity
    • Abed, É, Couchourel, D., Delalandre, A., Duval, N., Pelletier, J. P., Martel-Pelletier, J., & Lajeunesse, D. (2014). Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity. Bone, 59, 28–36.
    • (2014) Bone , vol.59 , pp. 28-36
    • Abed, É.1    Couchourel, D.2    Delalandre, A.3    Duval, N.4    Pelletier, J.P.5    Martel-Pelletier, J.6    Lajeunesse, D.7
  • 3
    • 84923923937 scopus 로고    scopus 로고
    • Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity
    • Abed, É, Bouvard, B., Martineau, X., Jouzeau, J. Y., Reboul, P., & Lajeunesse, D. (2015). Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity. Bone, 75, 111–119.
    • (2015) Bone , vol.75 , pp. 111-119
    • Abed, É.1    Bouvard, B.2    Martineau, X.3    Jouzeau, J.Y.4    Reboul, P.5    Lajeunesse, D.6
  • 4
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., Bauer, A., Stappert, J., Kispert, A., & Kemler, R. (1997). Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO Journal, 16, 3797–3804.
    • (1997) EMBO Journal , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 5
    • 40849106249 scopus 로고    scopus 로고
    • Osteocytes, mechanosensing and Wnt signaling
    • Bonewald, L. F., & Johnson, M. L. (2008). Osteocytes, mechanosensing and Wnt signaling. Bone, 42, 606–615.
    • (2008) Bone , vol.42 , pp. 606-615
    • Bonewald, L.F.1    Johnson, M.L.2
  • 6
    • 0030425363 scopus 로고    scopus 로고
    • Matrix proteins and mineralization: An overview
    • Boskey, A. L. (1996). Matrix proteins and mineralization: An overview. Connective Tissue Research, 35, 357–363.
    • (1996) Connective Tissue Research , vol.35 , pp. 357-363
    • Boskey, A.L.1
  • 7
    • 0032433142 scopus 로고    scopus 로고
    • Biomineralization: Conflicts, challenges, and opportunities
    • Boskey, A. L. (1998). Biomineralization: Conflicts, challenges, and opportunities. J Cell Biochem, Suppl 30-31, 83–91.
    • (1998) J Cell Biochem , vol.Suppl 30-31 , pp. 83-91
    • Boskey, A.L.1
  • 8
    • 84990985937 scopus 로고    scopus 로고
    • Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts
    • Bouvard, B., Abed, E., Yéléhé-Okouma, M., Bianchi, A., Mainard, D., Netter, P., … Reboul, P. (2014). Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts. Arthritis Res Ther, 16, 459.
    • (2014) Arthritis Res Ther , vol.16 , pp. 459
    • Bouvard, B.1    Abed, E.2    Yéléhé-Okouma, M.3    Bianchi, A.4    Mainard, D.5    Netter, P.6    Reboul, P.7
  • 9
    • 9444271026 scopus 로고    scopus 로고
    • Osteocalcin synthesis by human osteoblasts from normal and osteoarthritic bone after vitamin D3 stimulation
    • Cantatore, F. P., Corrado, A., Grano, M., Quarta, L., Colucci, S., & Melillo, N. (2004). Osteocalcin synthesis by human osteoblasts from normal and osteoarthritic bone after vitamin D3 stimulation. Clinical Rheumatology, 23, 490–495.
    • (2004) Clinical Rheumatology , vol.23 , pp. 490-495
    • Cantatore, F.P.1    Corrado, A.2    Grano, M.3    Quarta, L.4    Colucci, S.5    Melillo, N.6
  • 12
    • 84903440826 scopus 로고    scopus 로고
    • Hypoxia modulates the phenotype of osteoblasts isolated from knee osteoarthritis patients, leading to undermineralized bone nodule formation
    • Chang, J., Jackson, S. G., Wardale, J., & Jones, S. W. (2014). Hypoxia modulates the phenotype of osteoblasts isolated from knee osteoarthritis patients, leading to undermineralized bone nodule formation. Arthritis Rheumatol, 66, 1789–1799.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1789-1799
    • Chang, J.1    Jackson, S.G.2    Wardale, J.3    Jones, S.W.4
  • 13
    • 30344455321 scopus 로고    scopus 로고
    • Neridronate and human osteoblasts in normal, osteoporotic and osteoarthritic subjects
    • Corrado, A., Cantatore, F. P., Grano, M., & Colucci, S. (2005). Neridronate and human osteoblasts in normal, osteoporotic and osteoarthritic subjects. Clinical Rheumatology, 24, 527–534.
    • (2005) Clinical Rheumatology , vol.24 , pp. 527-534
    • Corrado, A.1    Cantatore, F.P.2    Grano, M.3    Colucci, S.4
  • 14
    • 84873711243 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in normal, osteoarthritic and osteoporotic osteoblasts
    • Corrado, A., Neve, A., & Cantatore, F. P. (2013). Expression of vascular endothelial growth factor in normal, osteoarthritic and osteoporotic osteoblasts. Clinical and Experimental Medicine, 13, 81–84.
    • (2013) Clinical and Experimental Medicine , vol.13 , pp. 81-84
    • Corrado, A.1    Neve, A.2    Cantatore, F.P.3
  • 16
    • 79955471159 scopus 로고    scopus 로고
    • Reduced tissue hardness of trabecular bone is associated with severe osteoarthritis
    • Dall'Ara, E., Ohman, C., Baleani, M., & Viceconti, M. (2011). Reduced tissue hardness of trabecular bone is associated with severe osteoarthritis. Journal of Biomechanics, 44, 1593–1598.
    • (2011) Journal of Biomechanics , vol.44 , pp. 1593-1598
    • Dall'Ara, E.1    Ohman, C.2    Baleani, M.3    Viceconti, M.4
  • 18
    • 0027453929 scopus 로고
    • Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis
    • Dequeker, J., Mohan, S., Finkelman, R. D., Aerssens, J., & Baylink, D. J. (1993). Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis. Arthritis & Rheumatism, 36, 1702–1708.
    • (1993) Arthritis & Rheumatism , vol.36 , pp. 1702-1708
    • Dequeker, J.1    Mohan, S.2    Finkelman, R.D.3    Aerssens, J.4    Baylink, D.J.5
  • 19
    • 80052763526 scopus 로고    scopus 로고
    • Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue
    • Dragojevič, J., Logar, D. B., Komadina, R., & Marc, J. (2011). Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue. Archives of Medical Research, 42, 392–397.
    • (2011) Archives of Medical Research , vol.42 , pp. 392-397
    • Dragojevič, J.1    Logar, D.B.2    Komadina, R.3    Marc, J.4
  • 20
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L., & Karsenty, G. (1997). Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell, 89, 747–754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 22
    • 0034543839 scopus 로고    scopus 로고
    • Altered bone mineral metabolism in patients with osteoarthritis
    • El Miedany, Y. M., Mehanna, A. N., & El Baddini, M. A. (2000). Altered bone mineral metabolism in patients with osteoarthritis. Joint Bone Spine, 67, 521–527.
    • (2000) Joint Bone Spine , vol.67 , pp. 521-527
    • El Miedany, Y.M.1    Mehanna, A.N.2    El Baddini, M.A.3
  • 23
    • 84895919105 scopus 로고    scopus 로고
    • Osteoblast-chondrocyte interactions in osteoarthritis
    • Findlay, D. M., & Atkins, G. J. (2014). Osteoblast-chondrocyte interactions in osteoarthritis. Current Osteoporosis Reports, 12, 127–134.
    • (2014) Current Osteoporosis Reports , vol.12 , pp. 127-134
    • Findlay, D.M.1    Atkins, G.J.2
  • 24
    • 84990622726 scopus 로고
    • Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers
    • Friedenstein, A. J., Chailakhyan, R. K., & Gerasimov, U. V. (1987). Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers. Cell and Tissue Kinetics, 20, 263–272.
    • (1987) Cell and Tissue Kinetics , vol.20 , pp. 263-272
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Gerasimov, U.V.3
  • 25
    • 0023484216 scopus 로고
    • Collagen and non-collagenous protein content (osteocalcin, sialoprotein, proteoglycan) in the iliac crest bone and serum osteocalcin in women with and without hand osteoarthritis
    • Gevers, G., & Dequeker, J. (1987). Collagen and non-collagenous protein content (osteocalcin, sialoprotein, proteoglycan) in the iliac crest bone and serum osteocalcin in women with and without hand osteoarthritis. Collagen and Related Research, 7, 435–442.
    • (1987) Collagen and Related Research , vol.7 , pp. 435-442
    • Gevers, G.1    Dequeker, J.2
  • 27
    • 0031957015 scopus 로고    scopus 로고
    • Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis
    • Hilal, G., Martel-Pelletier, J., Pelletier, J. P., Ranger, P., & Lajeunesse, D. (1998). Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis. Arthritis & Rheumatism, 41, 891–899.
    • (1998) Arthritis & Rheumatism , vol.41 , pp. 891-899
    • Hilal, G.1    Martel-Pelletier, J.2    Pelletier, J.P.3    Ranger, P.4    Lajeunesse, D.5
  • 28
    • 0034745062 scopus 로고    scopus 로고
    • Endogenous prostaglandin E2 and insulin like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts
    • Hilal, G., Massicotte, F., Martel-Pelletier, J., Fernandes, J. C., Pelletier, J. P., & Lajeunesse, D. (2001). Endogenous prostaglandin E2 and insulin like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts. Journal of Bone and Mineral Research, 16, 713–721.
    • (2001) Journal of Bone and Mineral Research , vol.16 , pp. 713-721
    • Hilal, G.1    Massicotte, F.2    Martel-Pelletier, J.3    Fernandes, J.C.4    Pelletier, J.P.5    Lajeunesse, D.6
  • 29
    • 3242781731 scopus 로고    scopus 로고
    • Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
    • Hofbauer, L. C., & Schoppet, M. (2004). Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA, 292, 490–495.
    • (2004) JAMA , vol.292 , pp. 490-495
    • Hofbauer, L.C.1    Schoppet, M.2
  • 30
    • 36949023800 scopus 로고    scopus 로고
    • Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signaling
    • Hopwood, B., Tsykin, A., Findlay, D. M., & Fazzalari, N. L. (2007). Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signaling. Arthritis Research & Therapy, 9, R100.
    • (2007) Arthritis Research & Therapy , vol.9 , pp. R100
    • Hopwood, B.1    Tsykin, A.2    Findlay, D.M.3    Fazzalari, N.L.4
  • 31
    • 85007495444 scopus 로고    scopus 로고
    • Expression of adipokines in osteoarthritis osteophytes and their effect on osteoblasts
    • [Epub ahead of print]
    • Junker, S., Frommer, K. W., Krumbholz, G., Tsiklauri, L., Gerstberger, R., Rehart, S., … Neumann, E. (2016). Expression of adipokines in osteoarthritis osteophytes and their effect on osteoblasts. Matrix Biol. Pii: S0945-053X(16), 30195–30190. https://doi.org10.1016/j.matbio.2016.11.005. [Epub ahead of print].
    • (2016) Matrix Biol , Issue.16 , pp. 30190-30195
    • Junker, S.1    Frommer, K.W.2    Krumbholz, G.3    Tsiklauri, L.4    Gerstberger, R.5    Rehart, S.6    Neumann, E.7
  • 32
    • 0033001286 scopus 로고    scopus 로고
    • Receptor activator of NF-kB recruits multiple TRAF family adaptors and activates c-jun N-terminal kinase
    • Kim, H. H., Lee, D. E., Shin, J. N., Lee, Y. S., Jeon, Y. M., Chung, C. H., … Lee, Z. H. (1999). Receptor activator of NF-kB recruits multiple TRAF family adaptors and activates c-jun N-terminal kinase. FEBS Letters, 443, 297–302.
    • (1999) FEBS Letters , vol.443 , pp. 297-302
    • Kim, H.H.1    Lee, D.E.2    Shin, J.N.3    Lee, Y.S.4    Jeon, Y.M.5    Chung, C.H.6    Lee, Z.H.7
  • 33
    • 0035868884 scopus 로고    scopus 로고
    • Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
    • Kobayashi, N., Kadono, Y., Naito, A., Matsumoto, K., Yamamoto, T., Tanaka, S., & Inoue, J. (2001). Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO Journal, 20, 1271–1280.
    • (2001) EMBO Journal , vol.20 , pp. 1271-1280
    • Kobayashi, N.1    Kadono, Y.2    Naito, A.3    Matsumoto, K.4    Yamamoto, T.5    Tanaka, S.6    Inoue, J.7
  • 34
    • 2142653473 scopus 로고    scopus 로고
    • Requisite roles of Runx2 and Cbfb in skeletal development
    • Komori, T. (2003). Requisite roles of Runx2 and Cbfb in skeletal development. Journal of Bone Mineral Metabolism, 21, 193–197.
    • (2003) Journal of Bone Mineral Metabolism , vol.21 , pp. 193-197
    • Komori, T.1
  • 35
    • 72449129934 scopus 로고    scopus 로고
    • Regulation of bone development and extracellularmatrix protein genes by RUNX2
    • Komori, T. (2010). Regulation of bone development and extracellularmatrix protein genes by RUNX2. Cell and Tissue Research, 339, 189–195.
    • (2010) Cell and Tissue Research , vol.339 , pp. 189-195
    • Komori, T.1
  • 36
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., … Kishimoto, T. (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell, 89, 755–764.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3    Yamaguchi, A.4    Sasaki, K.5    Deguchi, K.6    Kishimoto, T.7
  • 37
    • 84866453777 scopus 로고    scopus 로고
    • Evidence for the dysregulated expression of TWIST1, TGFβ1 and SMAD3 in differentiating osteoblasts from primary hip osteoarthritis patients
    • Kumarasinghe, D. D., Sullivan, T., Kuliwaba, J. S., Fazzalari, N. L., & Atkins, G. J. (2012). Evidence for the dysregulated expression of TWIST1, TGFβ1 and SMAD3 in differentiating osteoblasts from primary hip osteoarthritis patients. Osteoarthritis and Cartilage, 20, 1357–1366.
    • (2012) Osteoarthritis and Cartilage , vol.20 , pp. 1357-1366
    • Kumarasinghe, D.D.1    Sullivan, T.2    Kuliwaba, J.S.3    Fazzalari, N.L.4    Atkins, G.J.5
  • 39
    • 43349095508 scopus 로고    scopus 로고
    • The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells
    • Kwan Tat, S., Pelletier, J. P., Lajeunesse, D., Fahmi, H., Lavigne, M., & Martel-Pelletier, J. (2008). The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells. Clinical and Experimental Rheumatology, 26, 295–304.
    • (2008) Clinical and Experimental Rheumatology , vol.26 , pp. 295-304
    • Kwan Tat, S.1    Pelletier, J.P.2    Lajeunesse, D.3    Fahmi, H.4    Lavigne, M.5    Martel-Pelletier, J.6
  • 40
    • 0041328087 scopus 로고    scopus 로고
    • Subchondral bone in osteoarthritis: A biologic link with articular cartilage leading to abnormal remodeling
    • Lajeunesse, D., & Reboul, P. (2003). Subchondral bone in osteoarthritis: A biologic link with articular cartilage leading to abnormal remodeling. Current Opinion in Rheumatology, 15, 628–633.
    • (2003) Current Opinion in Rheumatology , vol.15 , pp. 628-633
    • Lajeunesse, D.1    Reboul, P.2
  • 41
    • 9844257577 scopus 로고    scopus 로고
    • Material properties of bone from the femoral neck and calcar femorale of patients with osteoporosis or osteoarthritis
    • Li, B., & Aspden, R. M. (1997). Material properties of bone from the femoral neck and calcar femorale of patients with osteoporosis or osteoarthritis. Osteoporosis International, 7, 450–456.
    • (1997) Osteoporosis International , vol.7 , pp. 450-456
    • Li, B.1    Aspden, R.M.2
  • 42
    • 0037155691 scopus 로고    scopus 로고
    • Control of bcatenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu, C., Li, Y., Semenov, M., Han, C., Baeg, G. H., Tan, Y., … He, X. (2002). Control of bcatenin phosphorylation/degradation by a dual-kinase mechanism. Cell, 108, 837–847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6    He, X.7
  • 45
    • 0032523186 scopus 로고    scopus 로고
    • Abnormal cancellous bone collagen metabolism in osteoarthritis
    • Mansell, J. P., & Bailey, A. J. (1998). Abnormal cancellous bone collagen metabolism in osteoarthritis. The Journal of Clinical Investigation, 101, 1596–1603.
    • (1998) The Journal of Clinical Investigation , vol.101 , pp. 1596-1603
    • Mansell, J.P.1    Bailey, A.J.2
  • 46
    • 0030753974 scopus 로고    scopus 로고
    • Biochemical evidence for altered subchondral bone collagen metabolism in osteoarthritis of the hip
    • Mansell, J. P., Tarlton, J. F., & Bailey, A. J. (1997). Biochemical evidence for altered subchondral bone collagen metabolism in osteoarthritis of the hip. British Journal of Rheumatology, 36, 16–19.
    • (1997) British Journal of Rheumatology , vol.36 , pp. 16-19
    • Mansell, J.P.1    Tarlton, J.F.2    Bailey, A.J.3
  • 50
    • 0036084062 scopus 로고    scopus 로고
    • Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients
    • Massicotte, F., Lajeunesse, D., Benderdour, M., Pelletier, J. P., Hilal, G., Duval, N., & Martel-Pelletier, J. (2002). Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients? Osteoarthritis and Cartilage, 10, 491–500.
    • (2002) Osteoarthritis and Cartilage , vol.10 , pp. 491-500
    • Massicotte, F.1    Lajeunesse, D.2    Benderdour, M.3    Pelletier, J.P.4    Hilal, G.5    Duval, N.6    Martel-Pelletier, J.7
  • 51
    • 0034613188 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kB ligand (RANKL)
    • Matsumoto, M., Sudo, T., Saito, T., Osada, H., & Tsujimoto, M. (2000). Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kB ligand (RANKL). The Journal of Biological Chemistry, 275, 31155–31161.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 31155-31161
    • Matsumoto, M.1    Sudo, T.2    Saito, T.3    Osada, H.4    Tsujimoto, M.5
  • 53
    • 45449087754 scopus 로고    scopus 로고
    • Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: A novel target for MMP-13 in osteoarthritis
    • Monfort, J., Tardif, G., Roughley, P., Reboul, P., Boileau, C., Bishop, P. N., … Martel-Pelletier, J. (2008). Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: A novel target for MMP-13 in osteoarthritis. Osteoarthritis and Cartilage, 16, 749–755.
    • (2008) Osteoarthritis and Cartilage , vol.16 , pp. 749-755
    • Monfort, J.1    Tardif, G.2    Roughley, P.3    Reboul, P.4    Boileau, C.5    Bishop, P.N.6    Martel-Pelletier, J.7
  • 54
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through b-catenin
    • Moon, R. T., Bowerman, B., Boutros, M., & Perrimon, N. (2002). The promise and perils of Wnt signaling through b-catenin. Science, 296, 1644–1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 55
    • 77955176027 scopus 로고    scopus 로고
    • Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression
    • Mutabaruka, M. S., Aoulad Aissa, M., Delalandre, A., Lavigne, M., & Lajeunesse, D. (2010). Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression. Arthritis Research & Therapy 12, R20.
    • (2010) Arthritis Research & Therapy , vol.12 , pp. R20
    • Mutabaruka, M.S.1    Aoulad Aissa, M.2    Delalandre, A.3    Lavigne, M.4    Lajeunesse, D.5
  • 56
    • 79953872127 scopus 로고    scopus 로고
    • Osteoblast physiology in normal and pathological conditions
    • Neve, A., Corrado, A., & Cantatore, F. P. (2011). Osteoblast physiology in normal and pathological conditions. Cell and Tissue Research, 343, 289–302.
    • (2011) Cell and Tissue Research , vol.343 , pp. 289-302
    • Neve, A.1    Corrado, A.2    Cantatore, F.P.3
  • 57
    • 0027184229 scopus 로고
    • Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha
    • Ogawa, E., Inuzuka, M., Maruyama, M., Satake, M., Naito-Fujimoto, M., Ito, Y., & Shigesada, K. (1993). Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha. Virology, 194, 314–331.
    • (1993) Virology , vol.194 , pp. 314-331
    • Ogawa, E.1    Inuzuka, M.2    Maruyama, M.3    Satake, M.4    Naito-Fujimoto, M.5    Ito, Y.6    Shigesada, K.7
  • 58
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto, F., Thornell, A. P., Crompton, T., Denzel, A., Gilmour, K. C., Rosewell, I. R., … Owen, M. J. (1997). Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell, 89, 765–771.
    • (1997) Cell , vol.89 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3    Denzel, A.4    Gilmour, K.C.5    Rosewell, I.R.6    Owen, M.J.7
  • 61
    • 84857863192 scopus 로고    scopus 로고
    • Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes—possible pathogenic role in osteoarthritis
    • Prasadam, I., Crawford, R., & Xiao, Y. (2012). Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes—possible pathogenic role in osteoarthritis. Journal of Rheumatology, 39, 621–634.
    • (2012) Journal of Rheumatology , vol.39 , pp. 621-634
    • Prasadam, I.1    Crawford, R.2    Xiao, Y.3
  • 62
    • 84885064836 scopus 로고    scopus 로고
    • Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: Role of integrinβ1 and focal adhesion kinase signaling cues
    • Prasadam, I., Farnaghi, S., Feng, J. Q., Gu, W., Perry, S., Crawford, R., & Xiao, Y. (2013). Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: Role of integrinβ1 and focal adhesion kinase signaling cues. Arthritis Research & Therapy, 15, R150.
    • (2013) Arthritis Research & Therapy , vol.15 , pp. R150
    • Prasadam, I.1    Farnaghi, S.2    Feng, J.Q.3    Gu, W.4    Perry, S.5    Crawford, R.6    Xiao, Y.7
  • 63
    • 44849105203 scopus 로고    scopus 로고
    • Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone
    • Sakao, K., Takahashi, K. A., Mazda, O., Arai, Y., Tonomura, H., Inoue, A., … Kubo, T. (2008). Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone. Journal of Orthopaedic Science, 13, 202–210.
    • (2008) Journal of Orthopaedic Science , vol.13 , pp. 202-210
    • Sakao, K.1    Takahashi, K.A.2    Mazda, O.3    Arai, Y.4    Tonomura, H.5    Inoue, A.6    Kubo, T.7
  • 64
    • 67749132440 scopus 로고    scopus 로고
    • Osteoblasts derived from osteophytes produce interleukin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis
    • Sakao, K., Takahashi, K. A., Arai, Y., Saito, M., Honjo, K., Hiraoka, N., … Kubo, T. (2009). Osteoblasts derived from osteophytes produce interleukin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis. Journal of Bone and Mineral Metabolism, 27, 412–423.
    • (2009) Journal of Bone and Mineral Metabolism , vol.27 , pp. 412-423
    • Sakao, K.1    Takahashi, K.A.2    Arai, Y.3    Saito, M.4    Honjo, K.5    Hiraoka, N.6    Kubo, T.7
  • 65
    • 27544466756 scopus 로고    scopus 로고
    • Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin M pre-treated non-sclerotic osteoblasts
    • Sanchez, C., Deberg, M. A., Piccardi, N., Msika, P., Reginster, J. Y., & Henrotin, Y. E. (2005). Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin M pre-treated non-sclerotic osteoblasts. Osteoarthritis and Cartilage, 13, 979–987.
    • (2005) Osteoarthritis and Cartilage , vol.13 , pp. 979-987
    • Sanchez, C.1    Deberg, M.A.2    Piccardi, N.3    Msika, P.4    Reginster, J.Y.5    Henrotin, Y.E.6
  • 66
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M. S., Lüthy, R., … Boyle, W. J. (1997). Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell, 89, 309–319.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.S.5    Lüthy, R.6    Boyle, W.J.7
  • 67
    • 84924809471 scopus 로고    scopus 로고
    • The emerging role of endothelin-1 in the pathogenesis of subchondral bone disturbance and osteoarthritis
    • Sin, A., Tang, W., Wen, C. Y., Chung, S. K., & Chiu, K. Y. (2015). The emerging role of endothelin-1 in the pathogenesis of subchondral bone disturbance and osteoarthritis. Osteoarthritis and Cartilage, 23, 516–524.
    • (2015) Osteoarthritis and Cartilage , vol.23 , pp. 516-524
    • Sin, A.1    Tang, W.2    Wen, C.Y.3    Chung, S.K.4    Chiu, K.Y.5
  • 69
    • 33748199511 scopus 로고    scopus 로고
    • OPG/membranous-RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation
    • Tat, S. K., Padrines, M., Theoleyre, S., Couillaud-Battaglia, S., Heymann, D., Redini, F., & Fortun, Y. (2006). OPG/membranous-RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation. Bone, 39, 706–715.
    • (2006) Bone , vol.39 , pp. 706-715
    • Tat, S.K.1    Padrines, M.2    Theoleyre, S.3    Couillaud-Battaglia, S.4    Heymann, D.5    Redini, F.6    Fortun, Y.7
  • 70
    • 52449116752 scopus 로고    scopus 로고
    • Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors
    • Tat, S. K., Pelletier, J. P., Lajeunesse, D., Fahmi, H., Duval, N., & Martel-Pelletier, J. (2008). Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors. Bone, 43, 284–291.
    • (2008) Bone , vol.43 , pp. 284-291
    • Tat, S.K.1    Pelletier, J.P.2    Lajeunesse, D.3    Fahmi, H.4    Duval, N.5    Martel-Pelletier, J.6
  • 74
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • Westendorf, J. J., Kahler, R. A., & Schroeder, T. M. (2004). Wnt signaling in osteoblasts and bone diseases. Gen, 341, 19–39.
    • (2004) Gen , vol.341 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 75
    • 33744791463 scopus 로고    scopus 로고
    • Wnt signaling: Is the party in the nucleus
    • Willert, K., & Jones, K. A. (2006). Wnt signaling: Is the party in the nucleus? Genes & Development, 20, 1394–1404.
    • (2006) Genes & Development , vol.20 , pp. 1394-1404
    • Willert, K.1    Jones, K.A.2
  • 76
    • 84963828867 scopus 로고    scopus 로고
    • Endothelin-1 induces oncostatin M expression in osteoarthritis osteoblasts by trans-activating the oncostatin M gene promoter via Ets-1
    • Wu, R., Wang, W., Huang, G., Mao, X., Chen, Y., Tang, Q., & Liao, L. (2016). Endothelin-1 induces oncostatin M expression in osteoarthritis osteoblasts by trans-activating the oncostatin M gene promoter via Ets-1. Molecular Medicine Reports, 13, 3559–3566.
    • (2016) Molecular Medicine Reports , vol.13 , pp. 3559-3566
    • Wu, R.1    Wang, W.2    Huang, G.3    Mao, X.4    Chen, Y.5    Tang, Q.6    Liao, L.7
  • 77
    • 0034455051 scopus 로고    scopus 로고
    • Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1
    • Yamaguchi, A., Komori, T., & Suda, T. (2000). Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocrine Reviews, 21, 393–411.
    • (2000) Endocrine Reviews , vol.21 , pp. 393-411
    • Yamaguchi, A.1    Komori, T.2    Suda, T.3
  • 78
    • 0242384747 scopus 로고    scopus 로고
    • Beta-catenin is critical for dendritic morphogenesis
    • Yu, X., & Malenka, R. C. (2003). Beta-catenin is critical for dendritic morphogenesis. Nature Neuroscience, 6, 1169–1177.
    • (2003) Nature Neuroscience , vol.6 , pp. 1169-1177
    • Yu, X.1    Malenka, R.C.2
  • 79
    • 84880297184 scopus 로고    scopus 로고
    • Inhibition of TGF-β signaling in mesenchymal stemcells of subchondral bone attenuates osteoarthritis
    • Zhen, G., Wen, C., Jia, X., Li, Y., Crane, JL., Mears, SC., … Cao, X. (2013). Inhibition of TGF-β signaling in mesenchymal stemcells of subchondral bone attenuates osteoarthritis. Nature Medicine, 19, 704–712.
    • (2013) Nature Medicine , vol.19 , pp. 704-712
    • Zhen, G.1    Wen, C.2    Jia, X.3    Li, Y.4    Crane, J.L.5    Mears, S.C.6    Cao, X.7


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