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Volumn 10, Issue 9, 2015, Pages

Altered expression of wnt signaling pathway components in osteogenesis of mesenchymal stem cells in osteoarthritis patients

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE KINASE; RNA; TRANSCRIPTION FACTOR; WNT PROTEIN; CELL SURFACE RECEPTOR; CTNNB1 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PROTEIN KINASE;

EID: 84944754754     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137170     Document Type: Article
Times cited : (35)

References (49)
  • 1
    • 0041328087 scopus 로고    scopus 로고
    • Subchondral bone in osteoarthritis: A biologic link with articular cartilage leading to abnormal remodeling
    • Epub 2003/09/10. PMID: 12960492
    • Lajeunesse D, Reboul P. Subchondral bone in osteoarthritis: a biologic link with articular cartilage leading to abnormal remodeling. Curr Opin Rheumatol. 2003; 15(5):628-33. Epub 2003/09/10. PMID: 12960492.
    • (2003) Curr Opin Rheumatol. , vol.15 , Issue.5 , pp. 628-633
    • Lajeunesse, D.1    Reboul, P.2
  • 2
    • 78650975710 scopus 로고    scopus 로고
    • The bone-cartilage unit in osteoarthritis
    • Epub 2010/12/08 PMID: 21135881
    • Lories RJ, Luyten FP. The bone-cartilage unit in osteoarthritis. Nat Rev Rheumatol. 2011; 7(1):43-9. Epub 2010/12/08. doi: 10.1038/nrrheum.2010.197 PMID: 21135881.
    • (2011) Nat Rev Rheumatol. , vol.7 , Issue.1 , pp. 43-49
    • Lories, R.J.1    Luyten, F.P.2
  • 3
    • 84855993582 scopus 로고    scopus 로고
    • Biomechanical factors in osteoarthritis
    • Epub 2012/01/24 PMID: 22265263; PubMed Central PMCID: PMC3266544 doi: 10.1016/j.berh.2011.11.013 S1521-6942(11)00169-0
    • Guilak F. Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheumatol. 2011; 25(6):815-23. Epub 2012/01/24. doi: S1521-6942(11)00169-0 [pii] 10.1016/j.berh.2011.11.013. PMID: 22265263; PubMed Central PMCID: PMC3266544. doi: 10.1016/j.berh.2011.11.013
    • (2011) Best Pract Res Clin Rheumatol. , vol.25 , Issue.6 , pp. 815-823
    • Guilak, F.1
  • 4
    • 84861978198 scopus 로고    scopus 로고
    • Genetic factors in OA pathogenesis
    • Epub 2011/12/20 PMID: 22178404 S8756-3282(11)01365-2
    • Chapman K, Valdes AM. Genetic factors in OA pathogenesis. Bone. 2012; 51(2):258-64. Epub 2011/12/20. doi: S8756-3282(11)01365-2 [pii] doi: 10.1016/j.bone.2011.11.026 PMID: 22178404.
    • (2012) Bone , vol.51 , Issue.2 , pp. 258-264
    • Chapman, K.1    Valdes, A.M.2
  • 5
    • 74549170849 scopus 로고    scopus 로고
    • Targeting subchondral bone for treating osteoarthritis: What is the evidence?
    • Epub 2010/02/05 PMID: 20129200 S1521-6942(09)00087-4
    • KwanTat S, Lajeunesse D, Pelletier JP, Martel-Pelletier J. Targeting subchondral bone for treating osteoarthritis: what is the evidence? Best Pract Res Clin Rheumatol. 2010; 24(1):51-70. Epub 2010/02/05. doi: S1521-6942(09)00087-4 [pii] doi: 10.1016/j.berh.2009.08.004 PMID: 20129200.
    • (2010) Best Pract Res Clin Rheumatol. , vol.24 , Issue.1 , pp. 51-70
    • KwanTat, S.1    Lajeunesse, D.2    Pelletier, J.P.3    Martel-Pelletier, J.4
  • 6
    • 0344394311 scopus 로고    scopus 로고
    • Osteoarthritis and osteoporosis: Clinical and research evidence of inverse relationship
    • Epub 2004/01/02. PMID: 14703009
    • Dequeker J, Aerssens J, Luyten FP. Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res. 2003; 15(5):426-39. Epub 2004/01/02. PMID: 14703009.
    • (2003) Aging Clin Exp Res. , vol.15 , Issue.5 , pp. 426-439
    • Dequeker, J.1    Aerssens, J.2    Luyten, F.P.3
  • 7
    • 84878164228 scopus 로고    scopus 로고
    • High bone mass is associated with an increased prevalence of joint replacement: A case-control study
    • Epub 2013/01/31 PMID: 23362220; PubMed Central PMCID: PMC3651613
    • Hardcastle SA, Gregson CL, Deere KC, Davey Smith G, Dieppe P, Tobias JH. High bone mass is associated with an increased prevalence of joint replacement: a case-control study. Rheumatology (Oxford). 2013; 52(6):1042-51. Epub 2013/01/31. doi: kes411 [pii] doi: 10.1093/rheumatology/kes411 PMID: 23362220; PubMed Central PMCID: PMC3651613.
    • (2013) Rheumatology (Oxford) , vol.52 , Issue.6 , pp. 1042-1051
    • Hardcastle, S.A.1    Gregson, C.L.2    Deere, K.C.3    Davey Smith, G.4    Dieppe, P.5    Tobias, J.H.6
  • 8
    • 84863637172 scopus 로고    scopus 로고
    • Mesenchymal stem cells for cartilage repair in osteoarthritis
    • Epub 2012/07/11 PMID: 22776206
    • Gupta PK, Das AK, Chullikana A, Majumdar AS. Mesenchymal stem cells for cartilage repair in osteoarthritis. Stem Cell Res Ther. 2012; 3(4):25. Epub 2012/07/11. doi: 10.1186/scrt116 PMID: 22776206.
    • (2012) Stem Cell Res Ther. , vol.3 , Issue.4 , pp. 25
    • Gupta, P.K.1    Das, A.K.2    Chullikana, A.3    Majumdar, A.S.4
  • 9
    • 43049131846 scopus 로고    scopus 로고
    • Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression
    • Epub 2008/05/15 PMID: 18477451 S1534-5807(08)00073-7
    • Mak KK, Bi Y, Wan C, Chuang PT, Clemens T, Young M, et al. Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression. Developmental cell. 2008; 14(5):674-88. Epub 2008/05/15. doi: S1534-5807(08)00073-7 [pii] doi: 10.1016/j.devcel.2008.02.003 PMID: 18477451.
    • (2008) Developmental Cell , vol.14 , Issue.5 , pp. 674-688
    • Mak, K.K.1    Bi, Y.2    Wan, C.3    Chuang, P.T.4    Clemens, T.5    Young, M.6
  • 10
    • 58149087220 scopus 로고    scopus 로고
    • Regulation of osteoarthritis development by wnt-beta-catenin signaling through the endochondral ossification process
    • Epub 2008/11/20 PMID: 19016582
    • Kawaguchi H. Regulation of osteoarthritis development by Wnt-beta-catenin signaling through the endochondral ossification process. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2009; 24(1):8-11. Epub 2008/11/20. doi: 10.1359/jbmr.081115 PMID: 19016582.
    • (2009) Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research , vol.24 , Issue.1 , pp. 8-11
    • Kawaguchi, H.1
  • 11
    • 53849125461 scopus 로고    scopus 로고
    • Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis
    • Epub 2008/09/30 PMID: 18820702
    • Corr M. Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis. Nature clinical practice Rheumatology. 2008; 4(10):550-6. Epub 2008/09/30. doi: ncprheum0904 [pii] doi: 10.1038/ncprheum0904 PMID: 18820702.
    • (2008) Nature Clinical Practice Rheumatology , vol.4 , Issue.10 , pp. 550-556
    • Corr, M.1
  • 12
    • 84873558051 scopus 로고    scopus 로고
    • WNT signaling in bone homeostasis and disease: From human mutations to treatments
    • Epub 2013/02/08 PMID: 23389618
    • Baron R, Kneissel M. WNT signaling in bone homeostasis and disease: from human mutations to treatments. Nat Med. 2013; 19(2):179-92. Epub 2013/02/08. doi: 10.1038/nm.3074 PMID: 23389618.
    • (2013) Nat Med. , vol.19 , Issue.2 , pp. 179-192
    • Baron, R.1    Kneissel, M.2
  • 13
    • 53849125461 scopus 로고    scopus 로고
    • Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis
    • Epub 2008/09/30 PMID: 18820702
    • Corr M. Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis. Nat Clin Pract Rheumatol. 2008; 4(10):550-6. Epub 2008/09/30. doi: ncprheum0904 [pii] doi: 10.1038/ncprheum0904 PMID: 18820702.
    • (2008) Nat Clin Pract Rheumatol. , vol.4 , Issue.10 , pp. 550-556
    • Corr, M.1
  • 14
    • 38849145169 scopus 로고    scopus 로고
    • The role of the wnt signaling pathway in osteoblast commitment and differentiation
    • Epub 2007/12/07. PMID: 18055419
    • Yavropoulou MP, Yovos JG. The role of the Wnt signaling pathway in osteoblast commitment and differentiation. Hormones (Athens). 2007; 6(4):279-94. Epub 2007/12/07. PMID: 18055419.
    • (2007) Hormones (Athens) , vol.6 , Issue.4 , pp. 279-294
    • Yavropoulou, M.P.1    Yovos, J.G.2
  • 15
    • 80053466165 scopus 로고    scopus 로고
    • Wnt/Ca2+ signaling pathway: Abrief overview
    • Epub 2011/09/10 PMID: 21903638
    • De A. Wnt/Ca2+ signaling pathway: abrief overview. Acta Biochim Biophys Sin (Shanghai). 2011; 43(10):745-56. Epub 2011/09/10. doi: 10.1093/abbs/gmr079 PMID: 21903638.
    • (2011) Acta Biochim Biophys Sin (Shanghai) , vol.43 , Issue.10 , pp. 745-756
    • De, A.1
  • 16
    • 80755130066 scopus 로고    scopus 로고
    • Wnt signaling signaling at and above the receptor level
    • Epub 2011/11/15 PMID: 22074601
    • Buechling T, Boutros M. Wnt signaling signaling at and above the receptor level. Curr Top Dev Biol. 2011; 97:21-53. Epub 2011/11/15. doi: 10.1016/B978-0-12-385975-4.00008-5 PMID: 22074601.
    • (2011) Curr Top Dev Biol. , vol.97 , pp. 21-53
    • Buechling, T.1    Boutros, M.2
  • 17
    • 67649595326 scopus 로고    scopus 로고
    • Identification of a stroma-mediated wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche
    • Epub 2009/06/03 PMID: 19489023
    • Kim JA, Kang YJ, Park G, Kim M, Park YO, Kim H, et al. Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. Stem Cells. 2009; 27(6):1318-29. Epub 2009/06/03. doi: 10.1002/stem.52 PMID: 19489023.
    • (2009) Stem Cells , vol.27 , Issue.6 , pp. 1318-1329
    • Kim, J.A.1    Kang, Y.J.2    Park, G.3    Kim, M.4    Park, Y.O.5    Kim, H.6
  • 18
    • 38349121930 scopus 로고    scopus 로고
    • Signaling pathways governing stem-cell fate
    • Epub 2007/10/05 PMID: 17914027
    • Blank U, Karlsson G, Karlsson S. Signaling pathways governing stem-cell fate. Blood. 2008; 111(2):492-503. Epub 2007/10/05. doi: 10.1182/blood-2007-07-075168 PMID: 17914027.
    • (2008) Blood , vol.111 , Issue.2 , pp. 492-503
    • Blank, U.1    Karlsson, G.2    Karlsson, S.3
  • 19
    • 39749139579 scopus 로고    scopus 로고
    • Wnt signaling in the niche
    • Epub 2008/03/11 PMID: 18329358
    • Suda T, Arai F. Wnt signaling in the niche. Cell. 2008; 132(5):729-30. Epub 2008/03/11. doi: 10.1016/j.cell.2008.02.017 PMID: 18329358.
    • (2008) Cell , vol.132 , Issue.5 , pp. 729-730
    • Suda, T.1    Arai, F.2
  • 20
    • 59649100796 scopus 로고    scopus 로고
    • Wnt signaling controls the fate of mesenchymal stem cells
    • Epub 2009/01/13 PMID: 19135507
    • Ling L, Nurcombe V, Cool SM. Wnt signaling controls the fate of mesenchymal stem cells. Gene. 2009; 433(1-2):1-7. Epub 2009/01/13. doi: 10.1016/j.gene.2008.12.008 PMID: 19135507.
    • (2009) Gene , vol.433 , Issue.1-2 , pp. 1-7
    • Ling, L.1    Nurcombe, V.2    Cool, S.M.3
  • 21
    • 84873900026 scopus 로고    scopus 로고
    • Anti-inflammatory role and immunomodulation of mesenchymal stem cells in systemic joint diseases: Potential for treatment
    • Epub 2013/01/09 PMID: 23293906
    • MacFarlane RJ, Graham SM, Davies PS, Korres N, Tsouchnica H, Heliotis M, et al. Anti-inflammatory role and immunomodulation of mesenchymal stem cells in systemic joint diseases: potential for treatment. Expert Opin Ther Targets. 2013; 17(3):243-54. Epub 2013/01/09. doi: 10.1517/14728222.2013.746954 PMID: 23293906.
    • (2013) Expert Opin Ther Targets , vol.17 , Issue.3 , pp. 243-254
    • MacFarlane, R.J.1    Graham, S.M.2    Davies, P.S.3    Korres, N.4    Tsouchnica, H.5    Heliotis, M.6
  • 22
    • 84881260492 scopus 로고    scopus 로고
    • Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation
    • Epub 2013/05/07 PMID: 23642066
    • Stagg J, Galipeau J. Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation. Curr Mol Med. 2013; 13(5):856-67. Epub 2013/05/07. doi: CMM-EPUB-20130502-15 [pii]. PMID: 23642066.
    • (2013) Curr Mol Med. , vol.13 , Issue.5 , pp. 856-867
    • Stagg, J.1    Galipeau, J.2
  • 23
    • 42949118331 scopus 로고    scopus 로고
    • Joint homeostasis, restoration, and remodeling in osteoarthritis
    • Epub 2008/05/06 PMID: 18455680 S1521-6942(07)00134-9
    • Lories RJ. Joint homeostasis, restoration, and remodeling in osteoarthritis. Best Pract Res Clin Rheumatol. 2008; 22(2):209-20. Epub 2008/05/06. doi: S1521-6942(07)00134-9 [pii] doi: 10.1016/j.berh.2007.12.001 PMID: 18455680.
    • (2008) Best Pract Res Clin Rheumatol. , vol.22 , Issue.2 , pp. 209-220
    • Lories, R.J.1
  • 25
    • 33646241997 scopus 로고    scopus 로고
    • Purified wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Epub 2006/04/11 PMID: 16602827; PubMed Central PMCID: PMC1420652 05-PLBI-RA-1339R3
    • Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 2006; 4(4):e115. Epub 2006/04/11. doi: 05-PLBI-RA-1339R3 [pii] doi: 10.1371/journal.pbio.0040115 PMID: 16602827; PubMed Central PMCID: PMC1420652.
    • (2006) PLoS Biol. , vol.4 , Issue.4 , pp. e115
    • Mikels, A.J.1    Nusse, R.2
  • 26
    • 78651070815 scopus 로고    scopus 로고
    • The wnt5a/Ror2 noncanonical signaling pathway inhibits canonical wnt signaling in K562 cells
    • Epub 2010/11/12 PMID: 21069266
    • Yuan Y, Niu CC, Deng G, Li ZQ, Pan J, Zhao C, et al. The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells. International journal of molecular medicine. 2011; 27(1):63-9. Epub 2010/11/12. doi: 10.3892/ijmm.2010.560 PMID: 21069266.
    • (2011) International Journal of Molecular Medicine , vol.27 , Issue.1 , pp. 63-69
    • Yuan, Y.1    Niu, C.C.2    Deng, G.3    Li, Z.Q.4    Pan, J.5    Zhao, C.6
  • 27
    • 84858007236 scopus 로고    scopus 로고
    • Wnt5a-ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
    • Epub 2012/02/22 PMID: 22344299
    • Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A, Mizoguchi T, et al. Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med. 2012; 18(3):405-12. Epub 2012/02/22. doi: nm.2653 [pii] doi: 10.1038/nm.2653 PMID: 22344299.
    • (2012) Nat Med. , vol.18 , Issue.3 , pp. 405-412
    • Maeda, K.1    Kobayashi, Y.2    Udagawa, N.3    Uehara, S.4    Ishihara, A.5    Mizoguchi, T.6
  • 28
    • 73949122296 scopus 로고    scopus 로고
    • WNT5A mutations in patients with autosomal dominant robinow syndrome
    • Epub 2009/11/18 PMID: 19918918
    • Person AD, Beiraghi S, Sieben CM, Hermanson S, Neumann AN, Robu ME, et al. WNT5A mutations in patients with autosomal dominant Robinow syndrome. Dev Dyn. 2010; 239(1):327-37. Epub 2009/11/18. doi: 10.1002/dvdy.22156 PMID: 19918918.
    • (2010) Dev Dyn , vol.239 , Issue.1 , pp. 327-337
    • Person, A.D.1    Beiraghi, S.2    Sieben, C.M.3    Hermanson, S.4    Neumann, A.N.5    Robu, M.E.6
  • 29
    • 0033616573 scopus 로고    scopus 로고
    • Biochemical characterization of wnt-frizzled interactions using a soluble, biologically active vertebrate wnt protein
    • Epub 1999/03/31. PMID: 10097073; PubMed Central PMCID: PMC22330
    • Hsieh JC, Rattner A, Smallwood PM, Nathans J. Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc Natl Acad Sci USA. 1999; 96(7):3546-51. Epub 1999/03/31. PMID: 10097073; PubMed Central PMCID: PMC22330.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.7 , pp. 3546-3551
    • Hsieh, J.C.1    Rattner, A.2    Smallwood, P.M.3    Nathans, J.4
  • 30
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • Epub 2004/10/12 PMID: 15474285 S0378-1119(04)00385-3
    • Westendorf JJ, Kahler RA, Schroeder TM. Wnt signaling in osteoblasts and bone diseases. Gene. 2004; 341:19-39. Epub 2004/10/12. doi: S0378-1119(04)00385-3 [pii] doi: 10.1016/j.gene.2004.06.044 PMID: 15474285.
    • (2004) Gene , vol.341 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 31
    • 2442548880 scopus 로고    scopus 로고
    • The human frizzled 6 (HFz6) acts as a negative regulator of the canonical wnt. Beta-catenin signaling cascade
    • Epub 2004/01/30 PMID: 14747478
    • Golan T, Yaniv A, Bafico A, Liu G, Gazit A. The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascade. J Biol Chem. 2004; 279(15):14879-88. Epub 2004/01/30. doi: 10.1074/jbc.M306421200 M306421200 [pii]. PMID: 14747478.
    • (2004) J Biol Chem. , vol.279 , Issue.15 , pp. 14879-14888
    • Golan, T.1    Yaniv, A.2    Bafico, A.3    Liu, G.4    Gazit, A.5
  • 32
    • 84859512183 scopus 로고    scopus 로고
    • Mutations in LRP5cause primary osteoporosis without features of OI by reducing wnt signaling activity
    • Epub 2012/04/11 PMID: 22487062; PubMed Central PMCID: PMC3374890
    • Korvala J, Juppner H, Makitie O, Sochett E, Schnabel D, Mora S, et al. Mutations in LRP5cause primary osteoporosis without features of OI by reducing Wnt signaling activity. BMC Med Genet. 2012; 13:26. Epub 2012/04/11. doi: 1471-2350-13-26 [pii] doi: 10.1186/1471-2350-13-26 PMID: 22487062; PubMed Central PMCID: PMC3374890.
    • (2012) BMC Med Genet. , vol.13 , pp. 26
    • Korvala, J.1    Juppner, H.2    Makitie, O.3    Sochett, E.4    Schnabel, D.5    Mora, S.6
  • 33
    • 0037373341 scopus 로고    scopus 로고
    • Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
    • Epub 2003/02/13 PMID: 12579474; PubMed Central PMCID: PMC1180253 S0002-9297(07)60594-1
    • Van Wesenbeeck L, Cleiren E, Gram J, Beals RK, Benichou O, Scopelliti D, et al. Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am J Hum Genet. 2003; 72(3):763-71. Epub 2003/02/13. doi: S0002-9297(07)60594-1 [pii] doi: 10.1086/368277 PMID: 12579474; PubMed Central PMCID: PMC1180253.
    • (2003) Am J Hum Genet. , vol.72 , Issue.3 , pp. 763-771
    • Van Wesenbeeck, L.1    Cleiren, E.2    Gram, J.3    Beals, R.K.4    Benichou, O.5    Scopelliti, D.6
  • 34
    • 33847671336 scopus 로고    scopus 로고
    • Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating dkk1-mediated inhibition of wnt signaling
    • Epub 2007/02/06 PMID: 17276019 S0378-1119(06)00767-0
    • Bhat BM, Allen KM, Liu W, Graham J, Morales A, Anisowicz A, et al. Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling. Gene. 2007; 391(1-2):103-12. Epub 2007/02/06. doi: S0378-1119(06)00767-0 [pii] doi: 10.1016/j.gene.2006.12.014 PMID: 17276019.
    • (2007) Gene , vol.391 , Issue.1-2 , pp. 103-112
    • Bhat, B.M.1    Allen, K.M.2    Liu, W.3    Graham, J.4    Morales, A.5    Anisowicz, A.6
  • 35
    • 79960615546 scopus 로고    scopus 로고
    • Identification of the first deletion in the LRP5genein a patient with autosomal dominant osteopetrosis type I
    • Epub 2011/05/24 PMID: 21600326; PubMed Central PMCID: PMC3149657 S8756-3282(11)00980-X
    • Pangrazio A, Boudin E, Piters E, Damante G, Lo Iacono N, D'Elia AV, et al. Identification of the first deletion in the LRP5genein a patient with autosomal dominant osteopetrosis type I. Bone. 2011; 49(3):568-71. Epub 2011/05/24. doi: S8756-3282(11)00980-X [pii] doi: 10.1016/j.bone.2011.05.006 PMID: 21600326; PubMed Central PMCID: PMC3149657.
    • (2011) Bone , vol.49 , Issue.3 , pp. 568-571
    • Pangrazio, A.1    Boudin, E.2    Piters, E.3    Damante, G.4    Lo Iacono, N.5    D'Elia, A.V.6
  • 36
    • 34447526757 scopus 로고    scopus 로고
    • Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of wnt signaling
    • Epub 2007/02/14 PMID: 17295608
    • Balemans W, Devogelaer JP, Cleiren E, Piters E, Caussin E, Van Hul W. Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling. J Bone Miner Res. 2007; 22(5):708-16. Epub 2007/02/14. doi: 10.1359/jbmr.070211 PMID: 17295608.
    • (2007) J Bone Miner Res. , vol.22 , Issue.5 , pp. 708-716
    • Balemans, W.1    Devogelaer, J.P.2    Cleiren, E.3    Piters, E.4    Caussin, E.5    Van Hul, W.6
  • 37
    • 79953169118 scopus 로고    scopus 로고
    • Sequential activation and inactivation of dishevelled in the wnt/beta-catenin pathway by casein kinases
    • Epub 2011/02/03 PMID: 21285348; PubMed Central PMCID: PMC3060493
    • Bernatik O, Ganji RS, Dijksterhuis JP, Konik P, Cervenka I, Polonio T, et al. Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases. J Biol Chem. 2011; 286(12):10396-410. Epub 2011/02/03. doi: M110.169870 [pii] doi: 10.1074/jbc.M110.169870 PMID: 21285348; PubMed Central PMCID: PMC3060493.
    • (2011) J Biol Chem. , vol.286 , Issue.12 , pp. 10396-10410
    • Bernatik, O.1    Ganji, R.S.2    Dijksterhuis, J.P.3    Konik, P.4    Cervenka, I.5    Polonio, T.6
  • 38
    • 33745865489 scopus 로고    scopus 로고
    • Casein kinase 2 is activated and essential for wnt/beta-catenin signaling
    • Epub 2006/05/05 PMID: 16672224
    • Gao Y, Wang HY. Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling. J Biol Chem. 2006; 281(27):18394-400. Epub 2006/05/05. doi: M601112200 [pii] doi: 10.1074/jbc.M601112200 PMID: 16672224.
    • (2006) J Biol Chem. , vol.281 , Issue.27 , pp. 18394-18400
    • Gao, Y.1    Wang, H.Y.2
  • 39
    • 84859300080 scopus 로고    scopus 로고
    • Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors
    • Epub 2012/01/26 PMID: 22275880; PubMed Central PMCID: PMC3223722
    • Mills CN, Nowsheen S, Bonner JA, Yang ES. Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors. Front Mol Neurosci. 2011; 4:47. Epub 2012/01/26. doi: 10.3389/fnmol.2011.00047 PMID: 22275880; PubMed Central PMCID: PMC3223722.
    • (2011) Front Mol Neurosci , vol.4 , pp. 47
    • Mills, C.N.1    Nowsheen, S.2    Bonner, J.A.3    Yang, E.S.4
  • 40
    • 0036571011 scopus 로고    scopus 로고
    • Axin-mediated CKI phosphorylation of beta-catenin at ser 45: A molecular switch for the wnt pathway
    • Epub 2002/05/10 PMID: 12000790; PubMed Central PMCID: PMC186245
    • Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M, et al. Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev. 2002; 16(9):1066-76. Epub 2002/05/10. doi: 10.1101/gad.230302 PMID: 12000790; PubMed Central PMCID: PMC186245.
    • (2002) Genes Dev , vol.16 , Issue.9 , pp. 1066-1076
    • Amit, S.1    Hatzubai, A.2    Birman, Y.3    Andersen, J.S.4    Ben-Shushan, E.5    Mann, M.6
  • 41
    • 84907581200 scopus 로고    scopus 로고
    • Mitogen activated protein kinase (MAPK)-regulated interactions between osterix and runx2 are critical for the transcriptional osteogenic program
    • Epub 2014/08/15 PMID: 25122769
    • Artigas N, Urena C, Rodriguez-Carballo E, Rosa JL, Ventura F. Mitogen activated protein kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program. J Biol Chem. 2014. Epub 2014/08/15. doi: M114.576793 [pii] doi: 10.1074/jbc.M114.576793 PMID: 25122769.
    • (2014) J Biol Chem.
    • Artigas, N.1    Urena, C.2    Rodriguez-Carballo, E.3    Rosa, J.L.4    Ventura, F.5
  • 42
    • 84857863192 scopus 로고    scopus 로고
    • Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes-possible pathogenic role in osteoarthritis
    • Epub 2012/01/17 PMID: 22247346
    • Prasadam I, Crawford R, Xiao Y. Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes-possible pathogenic role in osteoarthritis. The Journal of rheumatology. 2012; 39(3):621-34. Epub 2012/01/17. doi: jrheum.110777 [pii] doi: 10.3899/jrheum.110777 PMID: 22247346.
    • (2012) The Journal of Rheumatology , vol.39 , Issue.3 , pp. 621-634
    • Prasadam, I.1    Crawford, R.2    Xiao, Y.3
  • 43
    • 84884505578 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways in osteoblasts
    • Epub 2013/06/04 PMID: 23725048
    • Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annu Rev Cell Dev Biol. 2013; 29:63-79. Epub 2013/06/04. doi: 10.1146/annurev-cellbio-101512-122347 PMID: 23725048.
    • (2013) Annu Rev Cell Dev Biol. , vol.29 , pp. 63-79
    • Greenblatt, M.B.1    Shim, J.H.2    Glimcher, L.H.3
  • 46
    • 84878546253 scopus 로고    scopus 로고
    • To wnt or not to wnt: The bone and joint health dilemma
    • Epub 2013/03/06 PMID: 23459013
    • Lories RJ, Corr M, Lane NE. To Wnt or not to Wnt: the bone and joint health dilemma. Nat Rev Rheumatol. 2013; 9(6):328-39. Epub 2013/03/06. doi: nrrheum.2013.25 [pii] doi: 10.1038/nrrheum.2013.25 PMID: 23459013.
    • (2013) Nat Rev Rheumatol. , vol.9 , Issue.6 , pp. 328-339
    • Lories, R.J.1    Corr, M.2    Lane, N.E.3
  • 48
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Epub 2002/05/17 PMID: 12015390
    • Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, et al. High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med. 2002; 346(20):1513-21. Epub 2002/05/17. doi: 10.1056/NEJMoa013444346/20/1513 [pii]. PMID: 12015390.
    • (2002) N Engl J Med. , vol.346 , Issue.20 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3    Mitzner, L.4    Farhi, A.5    Mitnick, M.A.6
  • 49
    • 8844261126 scopus 로고    scopus 로고
    • Polymorphisms in the sclerosteosis/van buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
    • Epub 2004/10/30 PMID: 15514891; PubMed Central PMCID: PMC1182139 S0002-9297(07)60071-8
    • Uitterlinden AG, Arp PP, Paeper BW, Charmley P, Proll S, Rivadeneira F, et al. Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites. Am J Hum Genet. 2004; 75(6):1032-45. Epub 2004/10/30. doi: S0002-9297(07)60071-8 [pii] doi: 10.1086/426458 PMID: 15514891; PubMed Central PMCID: PMC1182139.
    • (2004) Am J Hum Genet. , vol.75 , Issue.6 , pp. 1032-1045
    • Uitterlinden, A.G.1    Arp, P.P.2    Paeper, B.W.3    Charmley, P.4    Proll, S.5    Rivadeneira, F.6


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