Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation

Biomedicine and Pharmacotherapy

Volumn 94, Issue , 2017, Pages 1-9

  Wu, Zhidi ^a   Ou, Ling ^a   Wang, Chaopeng ^a   Yang, Li ^a   Wang, Panpan ^b   Liu, Hengrui ^a   Xiong, Yingquan ^a   Sun, Kehuan ^a   Zhang, Ronghua ^a   Zhu, Xiaofeng ^b  

^a JINAN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

Author keywords

Estrogen receptor; Icaritin; Mitogen activated protein kinases; Osteoblastic differentiation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALKALINE PHOSPHATASE; CALCIUM BINDING PROTEIN; COLLAGEN TYPE 1; ESTROGEN RECEPTOR; FULVESTRANT; ICARIIN; ICARITIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCALCIN; OSTEOPONIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; FLAVONOID; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL VIABILITY; COLLAGEN SYNTHESIS; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; IN VITRO STUDY; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL CLONE; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; MAPK SIGNALING; METABOLISM; MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CLONE CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RECEPTORS, ESTROGEN;

EID: 85025099475     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.07.071     Document Type: Article

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