Ugonin K-stimulated osteogenesis involves estrogen receptor-dependent activation of non-classical Src signaling pathway and classical pathway

European Journal of Pharmacology

Volumn 676, Issue 1-3, 2012, Pages 26-33

  Lee, Chia Hsin ^a   Huang, Yu Ling ^b   Liao, Jyh Fei ^a   Chiou, Wen Fei ^a,b,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c HUNGKUANG UNIVERSITY   (Taiwan)

Author keywords

c Src; Estrogen receptor; Osteogenesis; Osterix; Runx2; Ugonin K

Indexed keywords

ALKALINE PHOSPHATASE; BONE SIALOPROTEIN; ESTROGEN RECEPTOR ALPHA; FLAVONOID; FULVESTRANT; OSTEOCALCIN; PROTEIN KINASE P60; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UGONIN K; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NONHUMAN; OSSIFICATION; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; RAT; UPREGULATION;

3T3-L1 CELLS; ACTIVE TRANSPORT, CELL NUCLEUS; ALKALINE PHOSPHATASE; ANIMALS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL NUCLEUS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FLAVONOIDS; HUMANS; MICE; ORGAN SPECIFICITY; OSTEOBLASTS; OSTEOGENESIS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84855586883     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.12.001     Document Type: Article

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