Icaritin suppresses the proliferation of human osteosarcoma cells in vitro by increasing apoptosis and decreasing MMP expression

Acta Pharmacologica Sinica

Volumn 35, Issue 4, 2014, Pages 531-539

  Wang, Xiao Fang ^a   Wang, Jun ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase 3; Icaritin; MMP 2; MMP 9; Osteosarcoma; zVAD fmk

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 9; FLAVONOID; GELATINASE A; GELATINASE B; ICARITIN; LIPOCORTIN 5; MESSENGER RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE INHIBITOR; HERBACEOUS AGENT; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; OSTEOSARCOMA; OSTEOSARCOMA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BONE TUMOR; CELL MOTION; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TIME; TUMOR CELL LINE; TUMOR INVASION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BONE NEOPLASMS; CASPASE 3; CASPASE 9; CASPASE INHIBITORS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; OSTEOSARCOMA; TIME FACTORS;

EID: 84898733035     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.178     Document Type: Article

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