메뉴 건너뛰기




Volumn 2, Issue MAR, 2014, Pages

HMGA proteins as modulators of chromatin structure during transcriptional activation

Author keywords

Chromatin structure; Development and cancer; HMGA; Transcription

Indexed keywords


EID: 85023631515     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2014.00005     Document Type: Review
Times cited : (113)

References (116)
  • 1
    • 0034069653 scopus 로고    scopus 로고
    • In vivo modulation of Hmgic reduces obesity
    • Anand, A., Chada, K. (2000). In vivo modulation of Hmgic reduces obesity. Nat. Genet. 24, 377-380. doi: 10.1038/74207.
    • (2000) Nat. Genet. , vol.24 , pp. 377-380
    • Anand, A.1    Chada, K.2
  • 2
    • 0042329754 scopus 로고    scopus 로고
    • Structure, function and evolution of CpG island promoters
    • Antequera, F. (2003). Structure, function and evolution of CpG island promoters. Cell. Mol. Life Sci. 60, 1647-1658. doi: 10.1007/s00018-003-2185-x.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 1647-1658
    • Antequera, F.1
  • 3
    • 0034933837 scopus 로고    scopus 로고
    • Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway
    • Baldassarre, G., Fedele, M., Battista, S., Vecchione, A., Klein-Szanto, A. J. P., Santoro, M., et al. (2001). Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway. Proc. Natl. Acad. Sci. U.S.A. 98, 7970-7975. doi: 10.1073/pnas.141224998.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 7970-7975
    • Baldassarre, G.1    Fedele, M.2    Battista, S.3    Vecchione, A.4    Klein-Szanto, A.J.P.5    Santoro, M.6
  • 5
    • 0028860339 scopus 로고
    • Inhibition of Hmgi-C protein-synthesis suppresses retrovirally induced neoplastic transformation of rat-thyroid cells
    • Berlingieri, M. T., Manfioletti, G., Santoro, M., Bandiera, A., Visconti, R., Giancotti, V., et al. (1995). Inhibition of Hmgi-C protein-synthesis suppresses retrovirally induced neoplastic transformation of rat-thyroid cells. Mol. Cell. Biol. 15, 1545-1553.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1545-1553
    • Berlingieri, M.T.1    Manfioletti, G.2    Santoro, M.3    Bandiera, A.4    Visconti, R.5    Giancotti, V.6
  • 6
    • 0034331936 scopus 로고    scopus 로고
    • An enhanceosome containing the Jun B/Fra-2 heterodimer and the HMG-I(Y) architectural protein controls HPV 18 transcription
    • Bouallaga, I., Massicard, S., Yaniv, M., Thierry, F. (2000). An enhanceosome containing the Jun B/Fra-2 heterodimer and the HMG-I(Y) architectural protein controls HPV 18 transcription. EMBO Rep. 1, 422-427. doi: 10.1093/embo-reports/kvd091.
    • (2000) EMBO Rep. , vol.1 , pp. 422-427
    • Bouallaga, I.1    Massicard, S.2    Yaniv, M.3    Thierry, F.4
  • 7
    • 0037377734 scopus 로고    scopus 로고
    • HMG-I(Y) and the CBP/p300 coactivator are essential for human papillomavirus type 18 enhanceosome transcriptional activity
    • Bouallaga, I., Teissier, S., Yaniv, M., Thierry, F. (2003). HMG-I(Y) and the CBP/p300 coactivator are essential for human papillomavirus type 18 enhanceosome transcriptional activity. Mol. Cell. Biol. 23, 2329-2340. doi: 10.1128/Mcb.23.7.2329-2340.2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2329-2340
    • Bouallaga, I.1    Teissier, S.2    Yaniv, M.3    Thierry, F.4
  • 8
    • 3042547563 scopus 로고    scopus 로고
    • Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2
    • Brants, J. R., Ayoubi, T. A. Y., Chada, K., Marchal, K., Van De Ven, W. J. M., Petit, M. M. R. (2004). Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2. FEBS Lett. 569, 277-283. doi: 10.1016/j.febslet.2004.05.075.
    • (2004) FEBS Lett. , vol.569 , pp. 277-283
    • Brants, J.R.1    Ayoubi, T.A.Y.2    Chada, K.3    Marchal, K.4    Van De Ven, W.J.M.5    Petit, M.M.R.6
  • 9
    • 0035282078 scopus 로고    scopus 로고
    • Revised nomenclature for high mobility group (HMG) chromosomal proteins
    • Bustin, M. (2001). Revised nomenclature for high mobility group (HMG) chromosomal proteins. Trends Biochem. Sci. 26, 152-153. doi: 10.1016/S0968-0004(00)01777-1.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 152-153
    • Bustin, M.1
  • 10
    • 0037108159 scopus 로고    scopus 로고
    • The RNA polymerase II core promoter: a key component in the regulation of gene expression
    • Butler, J. E. F., Kadonaga, J. T. (2002). The RNA polymerase II core promoter: a key component in the regulation of gene expression. Genes Dev. 16, 2583-2592. doi: 10.1101/Gad.1026202.
    • (2002) Genes Dev. , vol.16 , pp. 2583-2592
    • Butler, J.E.F.1    Kadonaga, J.T.2
  • 11
    • 42249109186 scopus 로고    scopus 로고
    • SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
    • Cao, X., Clavijo, C., Li, X., Lin, H. H., Chen, Y., Shih, H. M., et al. (2008). SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome. Mol. Cancer Ther. 7, 923-934. doi: 10.1158/1535-7163.mct-07-0540.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 923-934
    • Cao, X.1    Clavijo, C.2    Li, X.3    Lin, H.H.4    Chen, Y.5    Shih, H.M.6
  • 12
    • 30544446339 scopus 로고    scopus 로고
    • A new role for the oncogenic high-mobility group A2 transcription factor in myogenesis of embryonic stem cells
    • Caron, L., Bost, F., Prot, M., Hofman, P., Binetruy, B. (2005). A new role for the oncogenic high-mobility group A2 transcription factor in myogenesis of embryonic stem cells. Oncogene 24, 6281-6291. doi: 10.1038/sj.onc.1208781.
    • (2005) Oncogene , vol.24 , pp. 6281-6291
    • Caron, L.1    Bost, F.2    Prot, M.3    Hofman, P.4    Binetruy, B.5
  • 13
    • 34247198505 scopus 로고    scopus 로고
    • Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription
    • Casalino, L., Bakiri, L., Talotta, F., Weitzman, J. B., Fusco, A., Yaniv, M., et al. (2007). Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription. EMBO J. 26, 1878-1890. doi: 10.1038/sj.emboj.7601617.
    • (2007) EMBO J. , vol.26 , pp. 1878-1890
    • Casalino, L.1    Bakiri, L.2    Talotta, F.3    Weitzman, J.B.4    Fusco, A.5    Yaniv, M.6
  • 14
    • 74549135129 scopus 로고    scopus 로고
    • Binding and interplay of HMG proteins on chromatin: Lessons from live cell imaging
    • Catez, F., Hock, R. (2010). Binding and interplay of HMG proteins on chromatin: Lessons from live cell imaging. Biochim. Biophys. Acta Gene Regul. Mech. 1799, 15-27. doi: 10.1016/j.bbagrm.2009.11.001.
    • (2010) Biochim. Biophys. Acta Gene Regul. Mech. , vol.1799 , pp. 15-27
    • Catez, F.1    Hock, R.2
  • 15
    • 2942596544 scopus 로고    scopus 로고
    • Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin
    • Catez, F., Yang, H., Tracey, K. J., Reeves, R., Misteli, T., Bustin, M. (2004). Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol. Cell. Biol. 24, 4321-4328. doi: 10.1128/MCB.24.10.4321-4328.2004.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4321-4328
    • Catez, F.1    Yang, H.2    Tracey, K.J.3    Reeves, R.4    Misteli, T.5    Bustin, M.6
  • 16
    • 77749304818 scopus 로고    scopus 로고
    • DNA bending by the mammalian high-mobility group protein AT Hook 2
    • Chen, B., Young, J., Leng, F. F. (2010). DNA bending by the mammalian high-mobility group protein AT Hook 2. Biochemistry 49, 1590-1595. doi: 10.1021/Bi901881c.
    • (2010) Biochemistry , vol.49 , pp. 1590-1595
    • Chen, B.1    Young, J.2    Leng, F.F.3
  • 19
    • 34248233108 scopus 로고    scopus 로고
    • HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
    • Cleynen, I., Brants, J. R., Peeters, K., Deckers, R., Debiec-Rychter, M., Sciot, R., et al. (2007). HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB. Mol. Cancer Res. 5, 363-372. doi: 10.1158/1541-7786.MCR-06-0331.
    • (2007) Mol. Cancer Res. , vol.5 , pp. 363-372
    • Cleynen, I.1    Brants, J.R.2    Peeters, K.3    Deckers, R.4    Debiec-Rychter, M.5    Sciot, R.6
  • 20
    • 38849089984 scopus 로고    scopus 로고
    • The HMGA proteins: a myriad of functions (Review)
    • Available online at
    • Cleynen, I., Van De Ven, W. J. (2008). The HMGA proteins: a myriad of functions (Review). Int. J. Oncol. 32, 289-305. Available online at: http://www.spandidos-publications.com/ijo/32/2/289.
    • (2008) Int. J. Oncol. , vol.32 , pp. 289-305
    • Cleynen, I.1    Van De Ven, W.J.2
  • 21
    • 0242721659 scopus 로고    scopus 로고
    • The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation
    • Contreras, A., Hale, T. K., Stenoien, D. L., Rosen, J. M., Mancini, M. A., Herrera, R. E. (2003). The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol. Cell. Biol. 23, 8626-8636. doi: 10.1128/Mcb.23.23.8626-8636.2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8626-8636
    • Contreras, A.1    Hale, T.K.2    Stenoien, D.L.3    Rosen, J.M.4    Mancini, M.A.5    Herrera, R.E.6
  • 22
    • 84881460310 scopus 로고    scopus 로고
    • The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
    • Copley, M. R., Babovic, S., Benz, C., Knapp, D. J., Beer, P. A., Kent, D. G., et al. (2013). The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells. Nat. Cell Biol. 15, 916-925. doi: 10.1038/ncb2783.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 916-925
    • Copley, M.R.1    Babovic, S.2    Benz, C.3    Knapp, D.J.4    Beer, P.A.5    Kent, D.G.6
  • 23
    • 36048957227 scopus 로고    scopus 로고
    • Specific recognition of AT-Rich DNA sequences by the mammalian high mobility group-protein AT-hook 2: a SELEX study
    • Cui, T. J., Leng, F. F. (2007). Specific recognition of AT-Rich DNA sequences by the mammalian high mobility group-protein AT-hook 2: a SELEX study. Biochemistry 46, 13059-13066. doi: 10.1021/Bi701269s.
    • (2007) Biochemistry , vol.46 , pp. 13059-13066
    • Cui, T.J.1    Leng, F.F.2
  • 24
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton, A. M., Bird, A. (2011). CpG islands and the regulation of transcription. Genes Dev. 25, 1010-1022. doi: 10.1101/Gad.2037511.
    • (2011) Genes Dev. , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 25
    • 1542283801 scopus 로고    scopus 로고
    • Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes
    • Di Agostino, S., Fedele, M., Chieffi, P., Fusco, A., Rossi, P., Geremia, R., et al. (2004). Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes. Mol. Biol. Cell 15, 1224-1232. doi: 10.1091/mbc. E03-09-0638.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1224-1232
    • Di Agostino, S.1    Fedele, M.2    Chieffi, P.3    Fusco, A.4    Rossi, P.5    Geremia, R.6
  • 27
    • 15744362782 scopus 로고    scopus 로고
    • Dynamic and differential in vivo modifications of the isoform HMGA1a and HMGA1b chromatin proteins
    • Edberg, D. D., Adkins, J. N., Springer, D. L., Reeves, R. (2005). Dynamic and differential in vivo modifications of the isoform HMGA1a and HMGA1b chromatin proteins. J. Biol. Chem. 280, 8961-8973. doi: 10.1074/jbc. M407348200.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8961-8973
    • Edberg, D.D.1    Adkins, J.N.2    Springer, D.L.3    Reeves, R.4
  • 28
    • 4444277135 scopus 로고    scopus 로고
    • In vivo posttranslational modifications of the high mobility group A1a proteins in breast cancer cells of differing metastatic potential
    • Edberg, D. D., Bruce, J. E., Siems, W. F., Reeves, R. (2004). In vivo posttranslational modifications of the high mobility group A1a proteins in breast cancer cells of differing metastatic potential. Biochemistry 43, 11500-11515. doi: 10.1021/bi049833i.
    • (2004) Biochemistry , vol.43 , pp. 11500-11515
    • Edberg, D.D.1    Bruce, J.E.2    Siems, W.F.3    Reeves, R.4
  • 29
    • 0022552760 scopus 로고
    • Purification and postsynthetic modifications of Friend erythroleukemic cell high mobility group protein HMG-I
    • Elton, T. S., Reeves, R. (1986). Purification and postsynthetic modifications of Friend erythroleukemic cell high mobility group protein HMG-I. Anal. Biochem. 157, 53-62.
    • (1986) Anal. Biochem. , vol.157 , pp. 53-62
    • Elton, T.S.1    Reeves, R.2
  • 30
    • 70350012244 scopus 로고    scopus 로고
    • Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation
    • Esposito, F., Pierantoni, G. M., Battista, S., Melillo, R. M., Scala, S., Chieffi, P., et al. (2009). Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation. J. Biol. Chem. 284, 25993-26004. doi: 10.1074/jbc. M109.034280.
    • (2009) J. Biol. Chem. , vol.284 , pp. 25993-26004
    • Esposito, F.1    Pierantoni, G.M.2    Battista, S.3    Melillo, R.M.4    Scala, S.5    Chieffi, P.6
  • 31
    • 77954360253 scopus 로고    scopus 로고
    • High-Mobility Group A1 proteins regulate p53-mediated transcription of Bcl-2 Gene
    • Esposito, F., Tornincasa, M., Chieffi, P., De Martino, I., Pierantoni, G. M., Fusco, A. (2010). High-Mobility Group A1 proteins regulate p53-mediated transcription of Bcl-2 Gene. Cancer Res. 70, 5379-5388. doi: 10.1158/0008-5472.Can-09-4199.
    • (2010) Cancer Res. , vol.70 , pp. 5379-5388
    • Esposito, F.1    Tornincasa, M.2    Chieffi, P.3    De Martino, I.4    Pierantoni, G.M.5    Fusco, A.6
  • 32
    • 84865792218 scopus 로고    scopus 로고
    • High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria
    • Esposito, F., Tornincasa, M., Federico, A., Chiappetta, G., Pierantoni, G. M., Fusco, A. (2012). High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria. Cell Death Dis. 3:e383. doi: 10.1038/cddis.2012.126.
    • (2012) Cell Death Dis. , vol.3
    • Esposito, F.1    Tornincasa, M.2    Federico, A.3    Chiappetta, G.4    Pierantoni, G.M.5    Fusco, A.6
  • 33
    • 0028989950 scopus 로고
    • 1H and 13C NMR assignments and molecular modelling of a minor groove DNA-binding peptide from the HMG-I protein
    • Evans, J. N., Zajicek, J., Nissen, M. S., Munske, G., Smith, V., Reeves, R. (1995). 1H and 13C NMR assignments and molecular modelling of a minor groove DNA-binding peptide from the HMG-I protein. Int. J. Pept. Protein Res. 45, 554-560.
    • (1995) Int. J. Pept. Protein Res. , vol.45 , pp. 554-560
    • Evans, J.N.1    Zajicek, J.2    Nissen, M.S.3    Munske, G.4    Smith, V.5    Reeves, R.6
  • 35
    • 33645052445 scopus 로고    scopus 로고
    • Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice
    • Fedele, M., Fidanza, V., Battista, S., Pentimalli, F., Klein-Szanto, A. J. P., Visone, R., et al. (2006a). Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice. Cancer Res. 66, 2536-2543. doi: 10.1158/0008-5472.Can-05-1889.
    • (2006) Cancer Res. , vol.66 , pp. 2536-2543
    • Fedele, M.1    Fidanza, V.2    Battista, S.3    Pentimalli, F.4    Klein-Szanto, A.J.P.5    Visone, R.6
  • 36
    • 79251597652 scopus 로고    scopus 로고
    • Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice
    • Fedele, M., Visone, R., De Martino, I., Palmieri, D., Valentino, T., Esposito, F., et al. (2011). Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice. Eur. J. Cancer 47, 470-478. doi: 10.1016/j.ejca.2010.09.045.
    • (2011) Eur. J. Cancer , vol.47 , pp. 470-478
    • Fedele, M.1    Visone, R.2    De Martino, I.3    Palmieri, D.4    Valentino, T.5    Esposito, F.6
  • 37
    • 33744808027 scopus 로고    scopus 로고
    • HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity
    • Fedele, M., Visone, R., De Martino, I., Troncone, G., Palmieri, D., Battista, S., et al. (2006b). HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity. Cancer Cell 9, 459-471. doi: 10.1016/j.ccr.2006.04.024.
    • (2006) Cancer Cell , vol.9 , pp. 459-471
    • Fedele, M.1    Visone, R.2    De Martino, I.3    Troncone, G.4    Palmieri, D.5    Battista, S.6
  • 38
    • 22544482628 scopus 로고    scopus 로고
    • Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
    • Foti, D., Chiefari, E., Fedele, M., Iuliano, R., Brunetti, L., Paonessa, F., et al. (2005). Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat. Med. 11, 765-773. doi: 10.1038/nm1254.
    • (2005) Nat. Med. , vol.11 , pp. 765-773
    • Foti, D.1    Chiefari, E.2    Fedele, M.3    Iuliano, R.4    Brunetti, L.5    Paonessa, F.6
  • 39
    • 0037385239 scopus 로고    scopus 로고
    • A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription
    • Foti, D., Iuliano, R., Chiefari, E., Brunetti, A. (2003). A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Mol. Cell. Biol. 23, 2720-2732. doi: 10.1128/MCB.23.8.2720-2732.2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2720-2732
    • Foti, D.1    Iuliano, R.2    Chiefari, E.3    Brunetti, A.4
  • 40
    • 33645515483 scopus 로고    scopus 로고
    • HMGA1 inhibits the function of p53 family members in thyroid cancer cells
    • Frasca, F., Rustighi, A., Malaguarnera, R., Altamura, S., Vigneri, P., Del Sal, G., et al. (2006). HMGA1 inhibits the function of p53 family members in thyroid cancer cells. Cancer Res. 66, 2980-2989. doi: 10.1158/0008-5472.Can-05-2637.
    • (2006) Cancer Res. , vol.66 , pp. 2980-2989
    • Frasca, F.1    Rustighi, A.2    Malaguarnera, R.3    Altamura, S.4    Vigneri, P.5    Del Sal, G.6
  • 41
    • 0029813613 scopus 로고    scopus 로고
    • Involvement of a high-mobility-group protein in the transcriptional activity of herpes simplex virus latency-active promoter 2
    • French, S. W., Schmidt, M. C., Glorioso, J. C. (1996). Involvement of a high-mobility-group protein in the transcriptional activity of herpes simplex virus latency-active promoter 2. Mol. Cell. Biol. 16, 5393-5399.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5393-5399
    • French, S.W.1    Schmidt, M.C.2    Glorioso, J.C.3
  • 42
    • 36448992338 scopus 로고    scopus 로고
    • Roles of HMGA proteins in cancer
    • Fusco, A., Fedele, M. (2007). Roles of HMGA proteins in cancer. Nat. Rev. Cancer 7, 899-910. doi: 10.1038/Nrc2271.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 899-910
    • Fusco, A.1    Fedele, M.2
  • 43
    • 0022410391 scopus 로고
    • Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus
    • Giancotti, V., Berlingieri, M. T., Difiore, P. P., Fusco, A., Vecchio, G., Crane-Robinson, C. (1985). Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus. Cancer Res. 45, 6051-6057.
    • (1985) Cancer Res. , vol.45 , pp. 6051-6057
    • Giancotti, V.1    Berlingieri, M.T.2    Difiore, P.P.3    Fusco, A.4    Vecchio, G.5    Crane-Robinson, C.6
  • 44
    • 84874782710 scopus 로고    scopus 로고
    • DNA methylation mediated control of gene expression is critical for development of crown gall tumors
    • Gohlke, J., Scholz, C. J., Kneitz, S., Weber, D., Fuchs, J., Hedrich, R., et al. (2013). DNA methylation mediated control of gene expression is critical for development of crown gall tumors. PLoS Genet. 9:e1003267. doi: 10.1371/journal.pgen.1003267.
    • (2013) PLoS Genet. , vol.9
    • Gohlke, J.1    Scholz, C.J.2    Kneitz, S.3    Weber, D.4    Fuchs, J.5    Hedrich, R.6
  • 45
    • 24644439547 scopus 로고    scopus 로고
    • TGF-beta, neuronal stem cells and glioblastoma
    • Golestaneh, N., Mishra, B. (2005). TGF-beta, neuronal stem cells and glioblastoma. Oncogene 24, 5722-5730. doi: 10.1038/sj.onc.1208925.
    • (2005) Oncogene , vol.24 , pp. 5722-5730
    • Golestaneh, N.1    Mishra, B.2
  • 46
    • 79953296447 scopus 로고    scopus 로고
    • Coordinated histone modifications are associated with gene expression variation within and between species
    • Ha, M., Ng, D. W. K., Li, W. H., Chen, Z. J. (2011). Coordinated histone modifications are associated with gene expression variation within and between species. Genome Res. 21, 590-598. doi: 10.1101/gr.116467.110.
    • (2011) Genome Res. , vol.21 , pp. 590-598
    • Ha, M.1    Ng, D.W.K.2    Li, W.H.3    Chen, Z.J.4
  • 47
    • 57149133671 scopus 로고    scopus 로고
    • HMGA2, MicroRNAs, and Stem Cell Aging
    • Hammond, S. M., Sharpless, N. E. (2008). HMGA2, MicroRNAs, and Stem Cell Aging. Cell 135, 1013-1016. doi: 10.1016/j.cell.2008.11.026.
    • (2008) Cell , vol.135 , pp. 1013-1016
    • Hammond, S.M.1    Sharpless, N.E.2
  • 48
    • 0031792402 scopus 로고    scopus 로고
    • The expression pattern of the Hmgic gene during development
    • Hirning-Folz, U., Wilda, M., Rippe, V., Bullerdiek, J., Hameister, H. (1998). The expression pattern of the Hmgic gene during development. Genes Chromosomes Cancer 23, 350-357. doi: 10.1002/(Sici)1098-2264(199812)23:4<350::Aid-Gcc10>3.0.Co;2-E.
    • (1998) Genes Chromosomes Cancer , vol.23 , pp. 350-357
    • Hirning-Folz, U.1    Wilda, M.2    Rippe, V.3    Bullerdiek, J.4    Hameister, H.5
  • 49
    • 33846804545 scopus 로고    scopus 로고
    • HMG chromosomal proteins in development and disease
    • Hock, R., Furusawa, T., Ueda, T., Bustin, M. (2007). HMG chromosomal proteins in development and disease. Trends Cell Biol. 17, 72-79. doi: 10.1016/j.tcb.2006.12.001.
    • (2007) Trends Cell Biol. , vol.17 , pp. 72-79
    • Hock, R.1    Furusawa, T.2    Ueda, T.3    Bustin, M.4
  • 50
    • 70350497349 scopus 로고    scopus 로고
    • Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
    • Ikushima, H., Todo, T., Ino, Y., Takahashi, M., Miyazawa, K., Miyazono, K. (2009). Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 5, 504-514. doi: 10.1016/j.stem.2009.08.018.
    • (2009) Cell Stem Cell , vol.5 , pp. 504-514
    • Ikushima, H.1    Todo, T.2    Ino, Y.3    Takahashi, M.4    Miyazawa, K.5    Miyazono, K.6
  • 51
    • 33745255099 scopus 로고    scopus 로고
    • A topoisomerase II beta-mediated dsDNA break required for regulated transcription
    • Ju, B. G., Lunyak, V. V., Perissi, V., Garcia-Bassets, I., Rose, D. W., Glass, C. K., et al. (2006). A topoisomerase II beta-mediated dsDNA break required for regulated transcription. Science 312, 1798-1802. doi: 10.1126/science.1127196.
    • (2006) Science , vol.312 , pp. 1798-1802
    • Ju, B.G.1    Lunyak, V.V.2    Perissi, V.3    Garcia-Bassets, I.4    Rose, D.W.5    Glass, C.K.6
  • 52
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri, R., Weinberg, R. A. (2009). The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420-1428. doi: 10.1172/Jci39104.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 54
    • 84864474851 scopus 로고    scopus 로고
    • HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells
    • Kishi, Y., Fujii, Y., Hirabayashi, Y., Gotoh, Y. (2012). HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nat. Neurosci. 15, 1127-1133. doi: 10.1038/Nn.3165.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1127-1133
    • Kishi, Y.1    Fujii, Y.2    Hirabayashi, Y.3    Gotoh, Y.4
  • 55
    • 84892374204 scopus 로고    scopus 로고
    • HMGA2 functions as a competing endogenous RNA to promote lung cancer progression
    • Kumar, M. S., Armenteros-Monterroso, E., East, P., Chakravorty, P., Matthews, N., Winslow, M. M., et al. (2013). HMGA2 functions as a competing endogenous RNA to promote lung cancer progression. Nature 505, 212-217. doi: 10.1038/nature12785.
    • (2013) Nature , vol.505 , pp. 212-217
    • Kumar, M.S.1    Armenteros-Monterroso, E.2    East, P.3    Chakravorty, P.4    Matthews, N.5    Winslow, M.M.6
  • 56
    • 77954221282 scopus 로고    scopus 로고
    • Sequence features that drive human promoter function and tissue specificity
    • Landolin, J. M., Johnson, D. S., Trinklein, N. D., Aldred, S. F., Medina, C., Shulha, H., et al. (2010). Sequence features that drive human promoter function and tissue specificity. Genome Res. 20, 890-898. doi: 10.1101/gr.100370.109.
    • (2010) Genome Res. , vol.20 , pp. 890-898
    • Landolin, J.M.1    Johnson, D.S.2    Trinklein, N.D.3    Aldred, S.F.4    Medina, C.5    Shulha, H.6
  • 57
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee, Y. S., Dutta, A. (2007). The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 21, 1025-1030. doi: 10.1101/Gad.1540407.
    • (2007) Genes Dev. , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 58
    • 0024009983 scopus 로고
    • A conformational study of the sequence specific binding of Hmg-I (Y) with the Bovine Interleukin-2 Cdna
    • Lehn, D. A., Elton, T. S., Johnson, K. R., Reeves, R. (1988). A conformational study of the sequence specific binding of Hmg-I (Y) with the Bovine Interleukin-2 Cdna. Biochem. Int. 16, 963-971.
    • (1988) Biochem. Int. , vol.16 , pp. 963-971
    • Lehn, D.A.1    Elton, T.S.2    Johnson, K.R.3    Reeves, R.4
  • 59
    • 0037819447 scopus 로고    scopus 로고
    • Transcription regulation and animal diversity
    • Levine, M., Tjian, R. (2003). Transcription regulation and animal diversity. Nature 424, 147-151. doi: 10.1038/Nature01763.
    • (2003) Nature , vol.424 , pp. 147-151
    • Levine, M.1    Tjian, R.2
  • 60
    • 33751571757 scopus 로고    scopus 로고
    • High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells
    • Li, O., Vasudevan, D., Davey, C. A., Droge, P. (2006). High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells. Genesis 44, 523-529. doi: 10.1002/dvg.20242.
    • (2006) Genesis , vol.44 , pp. 523-529
    • Li, O.1    Vasudevan, D.2    Davey, C.A.3    Droge, P.4
  • 61
    • 84870856707 scopus 로고    scopus 로고
    • An HMGA2-IGF2BP2 Axis regulates myoblast proliferation and myogenesis
    • Li, Z. Z., Gilbert, J. A., Zhang, Y. Y., Zhang, M. S., Qiu, Q., Ramanujan, K., et al. (2012). An HMGA2-IGF2BP2 Axis regulates myoblast proliferation and myogenesis. Dev. Cell 23, 1176-1188. doi: 10.1016/j.devcel.2012.10.019.
    • (2012) Dev. Cell , vol.23 , pp. 1176-1188
    • Li, Z.Z.1    Gilbert, J.A.2    Zhang, Y.Y.3    Zhang, M.S.4    Qiu, Q.5    Ramanujan, K.6
  • 62
    • 0043269897 scopus 로고    scopus 로고
    • Hmga1 is required for normal sperm development
    • Liu, J., Schiltz, J. F., Ashar, H. R., Chada, K. K. (2003). Hmga1 is required for normal sperm development. Mol. Reprod. Dev. 66, 81-89. doi: 10.1002/mrd.10323.
    • (2003) Mol. Reprod. Dev. , vol.66 , pp. 81-89
    • Liu, J.1    Schiltz, J.F.2    Ashar, H.R.3    Chada, K.K.4
  • 64
    • 84879462597 scopus 로고    scopus 로고
    • The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1
    • Massimi, I., Guerrieri, F., Petroni, M., Veschi, V., Truffa, S., Screpanti, I., et al. (2013). The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1. Mol. Carcinog. 52, 526-534. doi: 10.1002/Mc.21887.
    • (2013) Mol. Carcinog. , vol.52 , pp. 526-534
    • Massimi, I.1    Guerrieri, F.2    Petroni, M.3    Veschi, V.4    Truffa, S.5    Screpanti, I.6
  • 65
    • 43049118632 scopus 로고    scopus 로고
    • A crucial role of a high mobility group protein HMGA2 in cardiogenesis
    • Monzen, K., Ito, Y., Naito, A. T., Kasai, H., Hiroi, Y., Hayashi, D., et al. (2008). A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Nat. Cell Biol. 10, 567-574. doi: 10.1038/Ncb1719.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 567-574
    • Monzen, K.1    Ito, Y.2    Naito, A.T.3    Kasai, H.4    Hiroi, Y.5    Hayashi, D.6
  • 67
    • 0035838991 scopus 로고    scopus 로고
    • Coordination of a transcriptional switch by HMGI(Y) acetylation
    • Munshi, N., Agalioti, T., Lomvardas, S., Merika, M., Chen, G. Y., Thanos, D. (2001). Coordination of a transcriptional switch by HMGI(Y) acetylation. Science 293, 1133-1136. doi: 10.1126/science.293.5532.1133.
    • (2001) Science , vol.293 , pp. 1133-1136
    • Munshi, N.1    Agalioti, T.2    Lomvardas, S.3    Merika, M.4    Chen, G.Y.5    Thanos, D.6
  • 68
    • 0032186185 scopus 로고    scopus 로고
    • Acetylation of HMG I(Y) by CBP turns offIFN beta expression by disrupting the enhanceosome
    • Munshi, N., Merika, M., Yie, J., Senger, K., Chen, G., Thanos, D. (1998). Acetylation of HMG I(Y) by CBP turns offIFN beta expression by disrupting the enhanceosome. Mol. Cell 2, 457-467.
    • (1998) Mol. Cell , vol.2 , pp. 457-467
    • Munshi, N.1    Merika, M.2    Yie, J.3    Senger, K.4    Chen, G.5    Thanos, D.6
  • 69
    • 0033511709 scopus 로고    scopus 로고
    • The IFN-beta enhancer: a paradigm for understanding activation and repression of inducible gene expression
    • Munshi, N., Yie, Y., Merika, M., Senger, K., Lomvardas, S., Agalioti, T., et al. (1999). The IFN-beta enhancer: a paradigm for understanding activation and repression of inducible gene expression. Cold Spring Harb. Symp. Quant. Biol. 64, 149-159.
    • (1999) Cold Spring Harb. Symp. Quant. Biol. , vol.64 , pp. 149-159
    • Munshi, N.1    Yie, Y.2    Merika, M.3    Senger, K.4    Lomvardas, S.5    Agalioti, T.6
  • 70
    • 84874624291 scopus 로고    scopus 로고
    • HMGA2 Inhibits Apoptosis through Interaction with ATR-CHK1 Signaling Complex in Human Cancer Cells
    • Natarajan, S., Hombach-Klonisch, S., Droge, P., Klonisch, T. (2013). HMGA2 Inhibits Apoptosis through Interaction with ATR-CHK1 Signaling Complex in Human Cancer Cells. Neoplasia 15, 263-280. doi: 10.1593/Neo.121988.
    • (2013) Neoplasia , vol.15 , pp. 263-280
    • Natarajan, S.1    Hombach-Klonisch, S.2    Droge, P.3    Klonisch, T.4
  • 71
    • 53749098061 scopus 로고    scopus 로고
    • Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
    • Nishino, J., Kim, I., Chada, K., Morrison, S. J. (2008). Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 135, 227-239. doi: 10.1016/j.cell.2008.09.017.
    • (2008) Cell , vol.135 , pp. 227-239
    • Nishino, J.1    Kim, I.2    Chada, K.3    Morrison, S.J.4
  • 72
    • 0025724096 scopus 로고
    • Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein
    • Nissen, M. S., Langan, T. A., Reeves, R. (1991). Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein. J. Biol. Chem. 266, 19945-19952.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19945-19952
    • Nissen, M.S.1    Langan, T.A.2    Reeves, R.3
  • 73
    • 79960065049 scopus 로고    scopus 로고
    • HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents
    • Palmieri, D., Valentino, T., D'angelo, D., De Martino, I., Postiglione, I., Pacelli, R., et al. (2011). HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents. Oncogene 30, 3024-3035. doi: 10.1038/Onc.2011.21.
    • (2011) Oncogene , vol.30 , pp. 3024-3035
    • Palmieri, D.1    Valentino, T.2    D'angelo, D.3    De Martino, I.4    Postiglione, I.5    Pacelli, R.6
  • 75
    • 41949113742 scopus 로고    scopus 로고
    • The enhanceosome
    • Panne, D. (2008). The enhanceosome. Curr. Opin. Struct. Biol. 18, 236-242. doi: 10.1016/j.sbi.2007.12.002.
    • (2008) Curr. Opin. Struct. Biol. , vol.18 , pp. 236-242
    • Panne, D.1
  • 76
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne, D., Maniatis, T., Harrison, S. C. (2007). An atomic model of the interferon-beta enhanceosome. Cell 129, 1111-1123. doi: 10.1016/j.cell.2007.05.019.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 78
    • 70349613017 scopus 로고    scopus 로고
    • The High Mobility Group Protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells? Stem Cell Rev
    • Pfannkuche, K., Summer, H., Li, O., Hescheler, J., Droge, P. (2009). The High Mobility Group Protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells? Stem Cell Rev. Rep. 5, 224-230. doi: 10.1007/s12015-009-9078-9.
    • (2009) Rep. , vol.5 , pp. 224-230
    • Pfannkuche, K.1    Summer, H.2    Li, O.3    Hescheler, J.4    Droge, P.5
  • 79
    • 0035959740 scopus 로고    scopus 로고
    • High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth
    • Pierantoni, G. M., Fedele, M., Pentimalli, F., Benvenuto, G., Pero, R., Viglietto, G., et al. (2001). High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth. Oncogene 20, 6132-6141. doi: 10.1038/sj.onc.1204635.
    • (2001) Oncogene , vol.20 , pp. 6132-6141
    • Pierantoni, G.M.1    Fedele, M.2    Pentimalli, F.3    Benvenuto, G.4    Pero, R.5    Viglietto, G.6
  • 80
    • 33747057745 scopus 로고    scopus 로고
    • High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity
    • Pierantoni, G. M., Rinaldo, C., Esposito, F., Mottolese, M., Soddu, S., Fusco, A. (2006). High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity. Cell Death Differ. 13, 1554-1563. doi: 10.1038/sj.cdd.4401839.
    • (2006) Cell Death Differ. , vol.13 , pp. 1554-1563
    • Pierantoni, G.M.1    Rinaldo, C.2    Esposito, F.3    Mottolese, M.4    Soddu, S.5    Fusco, A.6
  • 81
    • 33847398755 scopus 로고    scopus 로고
    • High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
    • Pierantoni, G. M., Rinaldo, C., Mottolese, M., Di Benedetto, A., Esposito, F., Soddu, S., et al. (2007). High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2. J. Clin. Invest. 117, 693-702. doi: 10.1172/Jc129852.
    • (2007) J. Clin. Invest. , vol.117 , pp. 693-702
    • Pierantoni, G.M.1    Rinaldo, C.2    Mottolese, M.3    Di Benedetto, A.4    Esposito, F.5    Soddu, S.6
  • 82
    • 67649669255 scopus 로고    scopus 로고
    • A unifying model for the selective regulation of inducible transcription by CpG Islands and nucleosome remodeling
    • Ramirez-Carrozzi, V. R., Braas, D., Bhatt, D. M., Cheng, C. S., Hong, C., Doty, K. R., et al. (2009). A unifying model for the selective regulation of inducible transcription by CpG Islands and nucleosome remodeling. Cell 138, 114-128. doi: 10.1016/j.cell.2009.04.020.
    • (2009) Cell , vol.138 , pp. 114-128
    • Ramirez-Carrozzi, V.R.1    Braas, D.2    Bhatt, D.M.3    Cheng, C.S.4    Hong, C.5    Doty, K.R.6
  • 83
    • 0035904395 scopus 로고    scopus 로고
    • Molecular biology of HMGA proteins: hubs of nuclear function
    • Reeves, R. (2001). Molecular biology of HMGA proteins: hubs of nuclear function. Gene 277, 63-81. doi: 10.1016/S0378-1119(01)00689-8.
    • (2001) Gene , vol.277 , pp. 63-81
    • Reeves, R.1
  • 84
    • 74549187994 scopus 로고    scopus 로고
    • Nuclear functions of the HMG proteins
    • Reeves, R. (2010). Nuclear functions of the HMG proteins. Biochim. Biophys. Acta Gene Regul. Mech. 1799, 3-14. doi: 10.1016/j.bbagrm.2009.09.001.
    • (2010) Biochim. Biophys. Acta Gene Regul. Mech. , vol.1799 , pp. 3-14
    • Reeves, R.1
  • 85
    • 0035164289 scopus 로고    scopus 로고
    • Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells
    • Reeves, R., Edberg, D. D., Li, Y. (2001). Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells. Mol. Cell. Biol. 21, 575-594. doi: 10.1128/Mcb.21.2.575-594.2001.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 575-594
    • Reeves, R.1    Edberg, D.D.2    Li, Y.3
  • 86
    • 59449110909 scopus 로고    scopus 로고
    • DOG 1.0: illustrator of protein domain structures
    • Ren, J., Wen, L., Gao, X., Jin, C., Xue, Y., Yao, X. (2009). DOG 1.0: illustrator of protein domain structures. Cell Res. 19, 271-273. doi: 10.1038/cr.2009.6.
    • (2009) Cell Res. , vol.19 , pp. 271-273
    • Ren, J.1    Wen, L.2    Gao, X.3    Jin, C.4    Xue, Y.5    Yao, X.6
  • 87
    • 0028892480 scopus 로고
    • Cell-cycle regulation of the cyclin-a gene promoter is mediated by a variant E2f site
    • Schulze, A., Zerfass, K., Spitkovsky, D., Middendorp, S., Berges, J., Helin, K., et al. (1995). Cell-cycle regulation of the cyclin-a gene promoter is mediated by a variant E2f site. Proc. Natl. Acad. Sci. U.S.A. 92, 11264-11268. doi: 10.1073/pnas.92.24.11264.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11264-11268
    • Schulze, A.1    Zerfass, K.2    Spitkovsky, D.3    Middendorp, S.4    Berges, J.5    Helin, K.6
  • 88
    • 33646141366 scopus 로고    scopus 로고
    • Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II
    • Schwabish, M. A., Struhl, K. (2006). Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II. Mol. Cell 22, 415-422. doi: 10.1016/j.molcel.2006.03.014.
    • (2006) Mol. Cell , vol.22 , pp. 415-422
    • Schwabish, M.A.1    Struhl, K.2
  • 89
    • 0034695478 scopus 로고    scopus 로고
    • Architecture of high mobility group protein I-C.DNA complex and its perturbation upon phosphorylation by Cdc2 kinase
    • Schwanbeck, R., Manfioletti, G., Wisniewski, J. R. (2000). Architecture of high mobility group protein I-C.DNA complex and its perturbation upon phosphorylation by Cdc2 kinase. J. Biol. Chem. 275, 1793-1801. doi: 10.1074/jbc.275.3.1793.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1793-1801
    • Schwanbeck, R.1    Manfioletti, G.2    Wisniewski, J.R.3
  • 90
    • 0037378828 scopus 로고    scopus 로고
    • During apoptosis of tumor cells HMGA1a protein undergoes methylation: identification of the modification site by mass spectrometry
    • Sgarra, R., Diana, F., Bellarosa, C., Dekleva, V., Rustighi, A., Toller, M., et al. (2003). During apoptosis of tumor cells HMGA1a protein undergoes methylation: identification of the modification site by mass spectrometry. Biochemistry 42, 3575-3585. doi: 10.1021/Bi0273381.
    • (2003) Biochemistry , vol.42 , pp. 3575-3585
    • Sgarra, R.1    Diana, F.2    Bellarosa, C.3    Dekleva, V.4    Rustighi, A.5    Toller, M.6
  • 91
    • 33645238282 scopus 로고    scopus 로고
    • The AT-hook of the chromatin architectural transcription factor high mobility group A1a is arginine-methylated by protein arginine methyltransferase 6
    • Sgarra, R., Lee, J., Tessari, M. A., Altamura, S., Spolaore, B., Giancotti, V., et al. (2006). The AT-hook of the chromatin architectural transcription factor high mobility group A1a is arginine-methylated by protein arginine methyltransferase 6. J. Biol. Chem. 281, 3764-3772. doi: 10.1074/jbc. M510231200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 3764-3772
    • Sgarra, R.1    Lee, J.2    Tessari, M.A.3    Altamura, S.4    Spolaore, B.5    Giancotti, V.6
  • 92
    • 4444288119 scopus 로고    scopus 로고
    • Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer
    • Sgarra, R., Rustighi, A., Tessari, M. A., Di Bernardo, J., Altamura, S., Fusco, A., et al. (2004). Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer. FEBS Lett. 574, 1-8. doi: 10.1016/j.febslet.2004.08.013.
    • (2004) FEBS Lett. , vol.574 , pp. 1-8
    • Sgarra, R.1    Rustighi, A.2    Tessari, M.A.3    Di Bernardo, J.4    Altamura, S.5    Fusco, A.6
  • 94
    • 55949131466 scopus 로고    scopus 로고
    • Characterization of post-translational modifications of the linker histones H1 and H5 from chicken erythrocytes using mass spectrometry
    • Snijders, A. P., Pongdam, S., Lambert, S. J., Wood, C. M., Baldwin, J. P., Dickman, M. J. (2008). Characterization of post-translational modifications of the linker histones H1 and H5 from chicken erythrocytes using mass spectrometry. J. Proteome Res. 7, 4326-4335. doi: 10.1021/pr800260a.
    • (2008) J. Proteome Res. , vol.7 , pp. 4326-4335
    • Snijders, A.P.1    Pongdam, S.2    Lambert, S.J.3    Wood, C.M.4    Baldwin, J.P.5    Dickman, M.J.6
  • 96
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J. P., Sleeman, J. P. (2006). Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7, 131-142. doi: 10.1038/nrm1835.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 97
    • 84865589321 scopus 로고    scopus 로고
    • How does Lin28 let-7 control development and disease?
    • Thornton, J. E., Gregory, R. I. (2012). How does Lin28 let-7 control development and disease? Trends Cell Biol. 22, 474-482. doi: 10.1016/j.tcb.2012.06.001.
    • (2012) Trends Cell Biol. , vol.22 , pp. 474-482
    • Thornton, J.E.1    Gregory, R.I.2
  • 98
    • 57749114754 scopus 로고    scopus 로고
    • HMGA2 and Smads Co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition
    • Thuault, S., Tan, E. J., Peinado, H., Cano, A., Heldin, C. H., Moustakas, A. (2008). HMGA2 and Smads Co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition. J. Biol. Chem. 283, 33437-33446. doi: 10.1074/jbc. M802016200.
    • (2008) J. Biol. Chem. , vol.283 , pp. 33437-33446
    • Thuault, S.1    Tan, E.J.2    Peinado, H.3    Cano, A.4    Heldin, C.H.5    Moustakas, A.6
  • 99
    • 33746034613 scopus 로고    scopus 로고
    • Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition
    • Thuault, S., Valcourt, U., Petersen, M., Manfioletti, G., Heldin, C. H., Moustakas, A. (2006). Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition. J. Cell Biol. 174, 175-183. doi: 10.1083/jcb.200512110.
    • (2006) J. Cell Biol. , vol.174 , pp. 175-183
    • Thuault, S.1    Valcourt, U.2    Petersen, M.3    Manfioletti, G.4    Heldin, C.H.5    Moustakas, A.6
  • 100
    • 0030863948 scopus 로고    scopus 로고
    • Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product
    • Vallone, D., Battista, S., Pierantoni, G. M., Fedele, M., Casalino, L., Santoro, M., et al. (1997). Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product. EMBO J. 16, 5310-5321. doi: 10.1093/emboj/16.17.5310.
    • (1997) EMBO J. , vol.16 , pp. 5310-5321
    • Vallone, D.1    Battista, S.2    Pierantoni, G.M.3    Fedele, M.4    Casalino, L.5    Santoro, M.6
  • 101
    • 0029123838 scopus 로고
    • Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin
    • Wang, D. Z., Ray, P., Boothby, M. (1995). Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin. J. Biol. Chem. 270, 22924-22932.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22924-22932
    • Wang, D.Z.1    Ray, P.2    Boothby, M.3
  • 102
    • 62549159932 scopus 로고    scopus 로고
    • HMGA2 Maintains Oncogenic RAS-Induced epithelial-mesenchymal transition in human pancreatic cancer cells
    • Watanabe, S., Ueda, Y., Akaboshi, S., Hino, Y., Sekita, Y., Nakao, M. (2009). HMGA2 Maintains Oncogenic RAS-Induced epithelial-mesenchymal transition in human pancreatic cancer cells. Am. J. Pathol. 174, 854-868. doi: 10.2353/ajpath.2009.080523.
    • (2009) Am. J. Pathol. , vol.174 , pp. 854-868
    • Watanabe, S.1    Ueda, Y.2    Akaboshi, S.3    Hino, Y.4    Sekita, Y.5    Nakao, M.6
  • 104
    • 79955020072 scopus 로고    scopus 로고
    • Chromatin Immunoprecipitation to Analyze DNA Binding Sites of HMGA2
    • Winter, N., Nimzyk, R., Bosche, C., Meyer, A., Bullerdiek, J. (2011). Chromatin Immunoprecipitation to Analyze DNA Binding Sites of HMGA2. PLoS ONE 6:e18837. doi: 10.1371/journal.pone.0018837.
    • (2011) PLoS ONE , vol.6
    • Winter, N.1    Nimzyk, R.2    Bosche, C.3    Meyer, A.4    Bullerdiek, J.5
  • 105
    • 0033881018 scopus 로고    scopus 로고
    • The oncogenic properties of the HMG-I gene family
    • Wood, L. J., Maher, J. F., Bunton, T. E., Resar, L. M. S. (2000). The oncogenic properties of the HMG-I gene family. Cancer Res. 60, 4256-4261.
    • (2000) Cancer Res. , vol.60 , pp. 4256-4261
    • Wood, L.J.1    Maher, J.F.2    Bunton, T.E.3    Resar, L.M.S.4
  • 106
    • 84885297798 scopus 로고    scopus 로고
    • HMGA2 and high-grade serous ovarian carcinoma
    • Wu, J. J., Wei, J. J. (2013). HMGA2 and high-grade serous ovarian carcinoma. J. Mol. Med. 91, 1155-1165. doi: 10.1007/s00109-013-1055-8.
    • (2013) J. Mol. Med. , vol.91 , pp. 1155-1165
    • Wu, J.J.1    Wei, J.J.2
  • 107
    • 78751509847 scopus 로고    scopus 로고
    • HMGA2 Overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT Genes
    • Wu, J. J., Liu, Z. J., Shao, C. S., Gong, Y. Q., Hernando, E., Lee, P., et al. (2011). HMGA2 Overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT Genes. Cancer Res. 71, 349-359. doi: 10.1158/0008-5472.Can-10-2550.
    • (2011) Cancer Res. , vol.71 , pp. 349-359
    • Wu, J.J.1    Liu, Z.J.2    Shao, C.S.3    Gong, Y.Q.4    Hernando, E.5    Lee, P.6
  • 108
    • 82955207566 scopus 로고    scopus 로고
    • Core promoter-selective function of HMGA1 and mediator in initiator-dependent transcription
    • Xu, M. Y., Sharma, P., Pan, S. Q., Malik, S., Roeder, R. G., Martinez, E. (2011). Core promoter-selective function of HMGA1 and mediator in initiator-dependent transcription. Genes Dev. 25, 2513-2524. doi: 10.1101/gad.177360.111.
    • (2011) Genes Dev. , vol.25 , pp. 2513-2524
    • Xu, M.Y.1    Sharma, P.2    Pan, S.Q.3    Malik, S.4    Roeder, R.G.5    Martinez, E.6
  • 109
    • 0033152497 scopus 로고    scopus 로고
    • The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome
    • Yie, J., Merika, M., Munshi, N., Chen, G., Thanos, D. (1999). The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome. EMBO J. 18, 3074-3089. doi: 10.1093/emboj/18.11.3074.
    • (1999) EMBO J. , vol.18 , pp. 3074-3089
    • Yie, J.1    Merika, M.2    Munshi, N.3    Chen, G.4    Thanos, D.5
  • 110
    • 84863985549 scopus 로고    scopus 로고
    • Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells
    • Zha, L., Wang, Z. W., Tang, W. X., Zhang, N., Liao, G., Huang, Z. (2012). Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells. Mol. Cell. Biochem. 364, 243-251. doi: 10.1007/s11010-012-1224-z.
    • (2012) Mol. Cell. Biochem. , vol.364 , pp. 243-251
    • Zha, L.1    Wang, Z.W.2    Tang, W.X.3    Zhang, N.4    Liao, G.5    Huang, Z.6
  • 111
    • 38049037736 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity
    • Zhang, Q., Wang, Y. (2007). Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity. J. Proteome Res. 6, 4711-4719. doi: 10.1021/pr700571d.
    • (2007) J. Proteome Res. , vol.6 , pp. 4711-4719
    • Zhang, Q.1    Wang, Y.2
  • 112
    • 34548130666 scopus 로고    scopus 로고
    • A quantitative study on the in vitro and in vivo acetylation of high mobility group A1 proteins
    • Zhang, Q., Zhang, K., Zou, Y., Perna, A., Wang, Y. (2007). A quantitative study on the in vitro and in vivo acetylation of high mobility group A1 proteins. J. Am. Soc. Mass Spectrom. 18, 1569-1578. doi: 10.1016/j.jasms.2007.05.020.
    • (2007) J. Am. Soc. Mass Spectrom. , vol.18 , pp. 1569-1578
    • Zhang, Q.1    Zhang, K.2    Zou, Y.3    Perna, A.4    Wang, Y.5
  • 113
    • 24344499512 scopus 로고    scopus 로고
    • Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription
    • Zhang, Y., Fatima, N., Dufau, M. L. (2005). Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription. Mol. Cell. Biol. 25, 7929-7939. doi: 10.1128/Mcb.25.18.7929-7939.2005.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7929-7939
    • Zhang, Y.1    Fatima, N.2    Dufau, M.L.3
  • 114
    • 0027306750 scopus 로고
    • Sar-dependent mobilization of histone H1 by Hmg-I/Y in-Vitro - Hmg-I/Y Is Enriched in H1-depleted chromatin
    • Zhao, K., Kas, E., Gonzalez, E., Laemmli, U. K. (1993). Sar-dependent mobilization of histone H1 by Hmg-I/Y in-Vitro - Hmg-I/Y Is Enriched in H1-depleted chromatin. EMBO J. 12, 3237-3247.
    • (1993) EMBO J. , vol.12 , pp. 3237-3247
    • Zhao, K.1    Kas, E.2    Gonzalez, E.3    Laemmli, U.K.4
  • 115
    • 0029094755 scopus 로고
    • Mutation Responsible for the Mouse Pygmy Phenotype in the Developmentally-Regulated Factor Hmgi-C
    • Zhou, X. J., Benson, K. F., Ashar, H. R., Chada, K. (1995). Mutation Responsible for the Mouse Pygmy Phenotype in the Developmentally-Regulated Factor Hmgi-C. Nature 376, 771-774. doi: 10.1038/376771a0.
    • (1995) Nature , vol.376 , pp. 771-774
    • Zhou, X.J.1    Benson, K.F.2    Ashar, H.R.3    Chada, K.4
  • 116
    • 80053481600 scopus 로고    scopus 로고
    • The Lin28/let-7 axis regulates glucose metabolism
    • Zhu, H., Shyh-Chang, N., Segre, A. V., Shinoda, G., Shah, S. P., Einhorn, W. S., et al. (2011). The Lin28/let-7 axis regulates glucose metabolism. Cell 147, 81-94. doi: 10.1016/j.cell.2011.08.033.
    • (2011) Cell , vol.147 , pp. 81-94
    • Zhu, H.1    Shyh-Chang, N.2    Segre, A.V.3    Shinoda, G.4    Shah, S.P.5    Einhorn, W.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.