Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

Cell

Volumn 170, Issue 2, 2017, Pages 260-272.e8

  Bushell, Ellen ^a   Gomes, Ana Rita ^a   Sanderson, Theo ^a   Anar, Burcu ^a   Girling, Gareth ^a   Herd, Colin ^a   Metcalf, Tom ^a   Modrzynska, Katarzyna ^a   Schwach, Frank ^a   Martin, Rowena E ^b   Mather, Michael W ^c   McFadden, Geoffrey I ^d   Parts, Leopold ^a   Rutledge, Gavin G ^a   Vaidya, Akhil B ^c   Wengelnik, Kai ^e   Rayner, Julian C ^a   Billker, Oliver ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

cancer immunology; cancer inflammation; carcinoma associated fibroblast (CAF); dendritic cells; interferon; lncRNA; myeloid cells; radiation resistance; triple negative breast cancer; tumor microenvironment

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA BARCODING; DRUG RESEARCH; ESSENTIAL GENE; FEMALE; GENE IDENTIFICATION; GENETIC PARAMETERS; GENETIC REDUNDANCY; GENOME ANALYSIS; GENOTYPE ENVIRONMENT INTERACTION; GROWTH RATE; HOST PARASITE INTERACTION; MOLECULAR EVOLUTION; MOUSE; MULTIGENE FAMILY; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; PRIORITY JOURNAL; PROTOZOAL GENETICS; RAT; ANIMAL; BAGG ALBINO MOUSE; EVOLUTION; GENE INACTIVATION; GENETICS; GENOME; GROWTH, DEVELOPMENT AND AGING; METABOLISM; SACCHAROMYCES CEREVISIAE; TOXOPLASMA; TRYPANOSOMA BRUCEI BRUCEI;

ANIMALS; BIOLOGICAL EVOLUTION; FEMALE; GENE KNOCKOUT TECHNIQUES; GENES, ESSENTIAL; GENOME, PROTOZOAN; HOST-PARASITE INTERACTIONS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED BALB C; PLASMODIUM BERGHEI; SACCHAROMYCES CEREVISIAE; TOXOPLASMA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 85023618715     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.06.030     Document Type: Article

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