Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity

Cell Discovery

Volumn 3, Issue , 2017, Pages

  He, Xiaoli ^a   Zhang, Wenjuan ^b   Yan, Chen ^c   Nie, Fen ^a   Li, Chen ^a   Liu, Xiaofen ^b   Fei, Cong ^a   Li, Shengdi ^a   Song, Xiaomin ^a   Jia, Yingying ^a   Zeng, Rong ^a   Wu, DIanqing ^d   Pan, Weijun ^b   Hao, Xiaojiang ^c   Li, Lin ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c KUNMING INSTITUTE OF BOTANY   (China)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CARF; chemical biology; NC043; small molecule; Wnt signaling

Indexed keywords

15 OXOSPIRAMILACTONE; BETA CATENIN; COLLABORATOR OF ARF PROTEIN; DISHEVELLED 1; DISHEVELLED 2; DISHEVELLED 3; DISHEVELLED PROTEIN; LACTONE DERIVATIVE; PROTEIN; PROTEIN C JUN; PROTEIN INHIBITOR; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CAUDAL FIN; CELL REGENERATION; CONTROLLED STUDY; COVALENT BOND; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; EMBRYO; EMBRYO DEVELOPMENT; HEMATOPOIETIC STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; WNT SIGNALING PATHWAY; ZEBRA FISH;

EID: 85022220538     PISSN: None     EISSN: 20565968     Source Type: Journal    
DOI: 10.1038/celldisc.2017.3     Document Type: Article

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