Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction

Nature Chemical Biology

Volumn 9, Issue 9, 2013, Pages 579-587

  Wang, Sheng ^a   Yin, Junlin ^b   Chen, Duozhi ^b   Nie, Fen ^a   Song, Xiaomin ^a   Fei, Cong ^a   Miao, Haofei ^a   Jing, Changbin ^c   Ma, Wenjing ^c   Wang, Lei ^b   Xie, Sichun ^a   Li, Chen ^a   Zeng, Rong ^a   Pan, Weijun ^c   Hao, Xiaojiang ^a,b   Li, Lin ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b KUNMING INSTITUTE OF BOTANY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 ETHYL 5 METHYL 5,6 DIHYDRO[1,3]DIOXOLO[4,5 J]PHENANTHRIDINE; AXIN; AXIN 2; BETA CATENIN; DICKKOPF 1 PROTEIN; HLY 78; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYCORINE; PROTEIN C MYB; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; WILD TYPE; WNT SIGNALING PATHWAY; ZEBRA FISH;

ANIMALS; AXIN PROTEIN; BENZODIOXOLES; HEK293 CELLS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; PHENANTHRIDINES; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; WNT PROTEINS; WNT SIGNALING PATHWAY; ZEBRAFISH;

DANIO RERIO;

EID: 84883185081     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1309     Document Type: Article

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