Zebrafish wnt8 Encodes Two Wnt8 Proteins on a Bicistronic Transcript and Is Required for Mesoderm and Neurectoderm Patterning

Developmental Cell

Volumn 1, Issue 1, 2001, Pages 103-114

  Lekven, Arne C ^a   Thorpe, Christopher J ^a   Waxman, Joshua S ^b   Moon, Randall T ^a  

^a Ctr Devmtl Biol Howard Hughes M   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DANIO RERIO; VERTEBRATA;

ANTISENSE OLIGONUCLEOTIDE; CYTOSKELETON PROTEIN; MESSENGER RNA; NTL PROTEIN, ZEBRAFISH; PROTEIN; T BOX TRANSCRIPTION FACTOR; TBX16 PROTEIN, ZEBRAFISH; WNT PROTEIN; WNT8A PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; ECTODERM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEAD; MESODERM; MOLECULAR GENETICS; MORPHOGENESIS; MUTAGENESIS; OPEN READING FRAME; PHENOTYPE; PHYSIOLOGY; PRENATAL DEVELOPMENT; TAIL; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; BODY PATTERNING; CYTOSKELETAL PROTEINS; ECTODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEAD; MESODERM; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OLIGONUCLEOTIDES, ANTISENSE; OPEN READING FRAMES; PHENOTYPE; PROTEINS; RNA, MESSENGER; T-BOX DOMAIN PROTEINS; TAIL; TRANSCRIPTION, GENETIC; WNT PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 0035404840     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(01)00007-7     Document Type: Article

References (49)

1. Amemiya C.T., Zhong T.P., Silverman G.A., Fishman M.C., Zon L.I. Zebrafish YAC, BAC, and PAC genomic libraries. Methods Cell Biol. 60:1999;235-258.
2. Bang A.G., Papalopulu N., Goulding M.D., Kintner C. Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm. Dev. Biol. 212:1999;366-380.
3. Brown A.M.C., Papkoff J., Fung Y.K., Shackleford G., Varmus H. Identification of protein products encoded by the proto-oncogene int-1. Mol. Cell. Biol. 7:1987;3971-3977.
4. Chomczynski P., Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
5. Christian J.L., Moon R.T. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7:1993;13-28.
6. Christian J.L., McMahon J.A., McMahon A.P., Moon R.T. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm- inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development. 111:1991;1045-1055.
7. Creancier L., Morello D., Mercier P., Prats A. Fibroblast growth factor 2 internal ribosome entry site (IRES) activity ex vivo and in transgenic mice reveals a stringent tissue-specific regulation. J. Cell Biol. 150:2000;275-281.
8. Evan G.I., Lewis G.K., Ramsay G., Bishop J.M. Isolation of monoclonal antibodies specific for human c-myc proto- oncogene product. Mol. Cell. Biol. 5:1985;3610-3616.
9. Fekany K., Yamanaka Y., Leung T., Sirotkin H.I., Topczewski J., Gates M.A., Hibi M., Renucci A., Stemple D., Radbill A.et al. The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development. 126:1999;1427-1438.
10. Fekany-Lee K., Gonzalez E., Miller-Bertoglio V., Solnica-Krezel L. The homeobox gene bozozok promotes anterior neuroectoderm formation in zebrafish through negative regulation of BMP2/4 and Wnt pathways. Development. 127:2000;2333-2345.
11. Glinka A., Wu W., Delius H., Monaghan A.P., Blumenstock C., Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 391:1998;357-362.
12. Griffin K., Patient R., Holder N. Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail. Development. 121:1995;2983-2994.
13. Griffin K.J., Amacher S.L., Kimmel C.B., Kimelman D. Molecular identification of spadetail. regulation of zebrafish trunk and tail mesoderm formation by T-box genes Development. 125:1998;3379-3388.
14. Grinblat Y., Gamse J., Patel M., Sive H. Determination of the zebrafish forebrain. induction and patterning Development. 125:1998;4403-4416.
15. Halpern M.E., Ho R.K., Walker C., Kimmel C.B. Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation. Cell. 75:1993;99-111.
16. Harland R. Neural induction. Curr. Opin. Genet. Dev. 10:2000;357-362.
17. Hoppler S., Moon R.T. BMP-2/-4 and Wnt-8 cooperatively pattern the Xenopus mesoderm. Mech. Dev. 71:1998;119-129.
18. Hoppler S., Brown J.D., Moon R.T. Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10:1996;2805-2817.
19. Hsieh J.C., Kodjabachian L., Rebbert M.L., Rattner A., Smallwood P.M., Samos C.H., Nusse R., Dawid I.B., Nathans J. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature. 398:1999;431-436.
20. Huez I., Creancier L., Audigier S., Gensac M., Prats A., Prats H. Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol. Cell. Biol. 18:1998;6178-6190.
21. Hug B., Walter V., Grunwald D.J. tbx6, a Brachyury-related gene expressed by ventral mesendodermal precursors in the zebrafish embryo. Dev. Biol. 183:1997;61-73.
22. Kazanskaya O., Glinka A., Niehrs C. The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning. Development. 127:2000;4981-4992.
23. Kelly G.M., Greenstein P., Erezyilmaz D.F., Moon R.T. Zebrafish wnt8 and wnt8b share a common activity but are involved in distinct developmental pathways. Development. 121:1995;1787-1799.
24. Kim C.-H., Oda T., Itoh M., Jiang D., Artinger K.B., Chandrasekharappa S.C., Driever W., Chitnis A.B. Repressor activity of headless/Tcf3 is essential for vertebrate head formation. Nature. 407:2000;913-916.
25. Kimmel C.B., Kane D.A., Walker C., Warga R.M., Rothman M.B. A mutation that changes cell movement and cell fate in the zebrafish embryo. Nature. 337:1989;358-362.
26. -/- colon carcinoma. Science. 275:1997;1784-1787.
27. Koshida S., Shinya M., Mizuno T., Kuroiwa A., Takeda H. Initial anteroposterior pattern of the zebrafish central nervous system is determined by differential competence of the epiblast. Development. 125:1998;1957-1966.
28. Krauss S., Johansen T., Korzh V., Fjose A. Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis. Development. 113:1991;1193-1206.
29. Lekven A.C., Helde K.A., Thorpe C.J., Rooke R., Moon R.T. Reverse genetics in zebrafish. Physiol. Genomics. 2:2000;37-48.
30. Leyns L., Bouwmeester T., Kim S.H., Piccolo S., De Robertis E.M. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell. 88:1997;747-756.
31. Li Y., Allende M.L., Finkelstein R., Weinberg E.S. Expression of two zebrafish orthodenticle-related genes in the embryonic brain. Mech. Dev. 48:1994;229-244.
32. McGrew L.L., Lai C.J., Moon R.T. Specification of the anteroposterior neural axis through synergistic interaction of the Wnt signaling cascade with noggin and follistatin. Dev. Biol. 172:1995;337-342.
33. McGrew L.L., Hoppler S., Moon R.T. Wnt and Fgf pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. Mech. Dev. 69:1997;105-114.
34. Nanbru C., Lafon I., Audigier S., Gensac M., Vagner S., Huez G., Prats A. Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J. Biol. Chem. 272:1997;32061-32066.
35. Nasevicius A., Ekker S.C. Effective targeted gene "knockdown" in zebrafish. Nat. Genet. 26:2000;216-220.
36. Oxtoby E., Jowett T. Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development. Nucleic Acids Res. 21:1993;1087-1095.
37. Pelletier J., Sonenberg N. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature. 334:1988;320-325.
38. Riley B.B., Grunwald D.J. Efficient induction of point mutations allowing recovery of specific locus mutations in zebrafish. Proc. Natl. Acad. Sci. USA. 92:1995;5997-6001.
39. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning. A Laboratory Manual:1989;Cold Spring Harbor Press, Cold Spring Harbor, NY.
40. Schulte-Merker S., van Eeden F.J., Halpern M.E., Kimmel C.B., Nusslein-Volhard C. no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development. 120:1994;1009-1015.
41. Solnica-Krezel L., Stemple D.L., Mountcastle-Shah E., Rangini Z., Neuhauss S.C., Malicki J., Schier A.F., Stainier D.Y., Zwartkruis F., Abdelilah S.et al. Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development. 123:1996;67-80.
42. Talbot W.S., Trevarrow B., Halpern M.E., Melby A.E., Farr G., Postlethwait J.H., Jowett T., Kimmel C.B., Kimelman D. A homeobox gene essential for zebrafish notochord development. Nature. 378:1995;150-157.
43. Tian Q., Nakayama T., Dixon M.P., Christian J.L. Post-transcriptional regulation of Xwnt-8 expression is required for normal myogenesis during vertebrate embryonic development. Development. 126:1999;3371-3380.
44. Turner D.L., Weintraub H. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. 8:1994;1434-1447.
45. Ungar A.R., Kelly G.M., Moon R.T. Wnt4 affects morphogenesis when misexpressed in the zebrafish embryo. Mech. Dev. 52:1995;153-164.
46. Weinberg E.S., Allende M.L., Kelly C.S., Abdelhamid A., Murakami T., Andermann P., Doerre O.G., Grunwald D.J., Riggleman B. Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos. Development. 122:1996;271-280.
47. Westerfield M. The Zebrafish Book. A Guide for the Laboratory Use of Zebrafish:1995;Eugene, OR: University of Oregon Press, Danio rerio). , Third Edition.
48. Wodarz A., Nusse R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14:1998;59-88.
49. Woo K., Fraser S.E. Specification of the zebrafish nervous system by nonaxial signals. Science. 277:1997;254-257.