Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

International Journal of Oncology

Volumn 51, Issue 2, 2017, Pages 533-544

  Cusimano, Antonella ^a   Balasus, Daniele ^a   Azzolina, Antonina ^a   Augello, Giuseppa ^a   Emma, Maria R ^a   Di Sano, Caterina ^a   Gramignoli, Roberto ^b   Strom, Stephen C ^b   McCubrey, James A ^c   Montalto, Giuseppe ^a,d   Cervello, Melchiorre ^a  

^a CNR   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

^c EAST CAROLINA UNIVERSITY   (United States)

^d UNIVERSITY OF PALERMO   (Italy)

Author keywords

Apoptosis; Colorectal carcinoma; Extra virgin olive oil; Hepatocellular carcinoma; Oleocanthal; Reactive oxygen species

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CASPASE 3; CASPASE 7; CYCLOOXYGENASE 2; HISTONE H2AX; IBUPROFEN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NIMESULIDE; OLEOCANTHAL; PHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; ALDEHYDE; OLIVE OIL; PROSTAGLANDIN SYNTHASE INHIBITOR;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CHROMATIN CONDENSATION; COLON CANCER CELL LINE; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; LIVER CANCER CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; CELL PROLIFERATION; CHEMISTRY; COLORECTAL TUMOR; DIET THERAPY; DRUG EFFECT; ENZYMOLOGY; HEP-G2 CELL LINE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY;

ALDEHYDES; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLOOXYGENASE INHIBITORS; DNA DAMAGE; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; OLIVE OIL; PHENOLS; REACTIVE OXYGEN SPECIES;

EID: 85021809554     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2017.4049     Document Type: Article

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