-
1
-
-
65549099309
-
Zalypsis: A novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to dna doublestrand breaks
-
Ocio E.M.; Maiso, P.; Chen, X.; Garayoa, M.; Alvarez-Fernández, S.; San-Segundo, L.; Vilanova, D.; López-Corral, L.; Montero, J.C.; Hernández-Iglesias, T.; de Alava, E.; Galmarini, C.; Avilés, P.; Cuevas, C.; San-Miguel, J.F.; Pandiella, A. Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA doublestrand breaks. Blood, 2009, 113, 3781-3791.
-
(2009)
Blood
, vol.113
, pp. 3781-3791
-
-
Ocio, E.M.1
Maiso, P.2
Chen, X.3
Garayoa, M.4
Alvarez-Fernández, S.5
San-Segundo, L.6
Vilanova, D.7
López-Corral, L.8
Montero, J.C.9
Hernández-Iglesias, T.10
De Alava, E.11
Galmarini, C.12
Avilés, P.13
Cuevas, C.14
San-Miguel, J.F.15
Pandiella, A.16
-
2
-
-
84862512787
-
Thalidomide maintenance therapy for patients with multiple myeloma: Meta-analysis
-
Kagoya, Y.; Nannya, Y.; Kurokawa, M. Thalidomide maintenance therapy for patients with multiple myeloma: Meta-analysis. Leuk. Res., 36 (8), 1016-1021.
-
Leuk. Res
, vol.36
, Issue.8
, pp. 1016-1021
-
-
Kagoya, Y.1
Nannya, Y.2
Kurokawa, M.3
-
3
-
-
84862841567
-
Impact of bortezomib on bone health in myeloma: A review of current evidence
-
in press, doi:10.1016/j.ctrv.2011.12.007
-
Zangari, M.; Terpos, E.; Zhan, F.; Tricot, G. Impact of bortezomib on bone health in myeloma: A review of current evidence. Cancer Treat. Rev., in press, doi:10.1016/j.ctrv.2011.12.007.
-
Cancer Treat. Rev
-
-
Zangari, M.1
Terpos, E.2
Zhan, F.3
Tricot, G.4
-
4
-
-
84858283875
-
Lenalidomide in multiple myeloma: Current experimental and clinical data
-
Cives, M.; Milano, A.; Dammacco, F.; Silvestris, F. Lenalidomide in multiple myeloma: current experimental and clinical data. Eur. J. Haematol., 2012, 88, 279-291.
-
(2012)
Eur. J. Haematol
, vol.88
, pp. 279-291
-
-
Cives, M.1
Milano, A.2
Dammacco, F.3
Silvestris, F.4
-
5
-
-
82255169321
-
Proteasome inhibitors and modulators of angiogenesis in multiple myeloma
-
Ferrarin, M.; Ferrero, E.; Proteasome inhibitors and modulators of angiogenesis in multiple myeloma. Curr. Med. Chem., 2011, 18 (34), 5185-5195.
-
(2011)
Curr. Med. Chem
, vol.18
, Issue.34
, pp. 5185-5195
-
-
Ferrarin, M.1
Ferrero, E.2
-
6
-
-
78751498789
-
The role of survivin for radiation oncology: Moving beyon apoptosis inhibition
-
Rödel, F.; Reichert, S.; Sprenger, T.; Gaipl, U.S.; Mirsch, J.; Liersch, T.; Fulda, S.; Rödel, C. The role of Survivin for Radiation Oncology: Moving Beyon Apoptosis Inhibition. Curr. Med. Chem., 2011, 8, 191-199.
-
(2011)
Curr. Med. Chem
, vol.8
, pp. 191-199
-
-
Rödel, F.1
Reichert, S.2
Sprenger, T.3
Gaipl, U.S.4
Mirsch, J.5
Liersch, T.6
Fulda, S.7
Rödel, C.8
-
7
-
-
0029994074
-
Therapeutic strategies for inhibition of interleukin-6 mediated multiple myeloma cell growth
-
DOI 10.1016/0145-2126(95)00085-2
-
Ogata, A.; Anderson, K.C. Therapeutic strategies for inhibition of interleukin-6 mediated multiple myeloma cell growth. Leuk. Res., 1996, 20, 303-307. (Pubitemid 26168268)
-
(1996)
Leukemia Research
, vol.20
, Issue.4
, pp. 303-307
-
-
Ogata, A.1
Anderson, K.C.2
-
8
-
-
0030948787
-
Blockade of mitogen-activated protein kinase cascade signaling in interleukin 6-independent multiple myeloma cells
-
Ogata, A.; Chauhan, D.; Urashima, M.; Teoh, G.; Treon, S.P.; Anderson, K. C. Blockade of mitogen-activated protein kinase cascade signaling in interleukin 6-independent multiple myeloma cells. Clin. Cancer Res., 1997, 3, 1017-1022. (Pubitemid 27253011)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.6
, pp. 1017-1022
-
-
Ogata, A.1
Chauhan, D.2
Urashima, M.3
Teoh, G.4
Treon, S.P.5
Anderson, K.C.6
-
9
-
-
34648814031
-
Macrophage inflammatory protein-1α (MIP-1α) enhances a receptor activator of nuclear factor κB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/ Akt pathways
-
DOI 10.1007/s11010-007-9485-7
-
Tsubaki, M.; Kato, C.; Manno, M.; Ogaki, M.; Satou, T.; Itoh, T.; Kusunoki, T.; Tanimori, Y.; Fujiwara, K.; Matsuoka, H.; Nishida, S. Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways. Mol. Cell Biochem., 2007, 304, 53-60. (Pubitemid 47456852)
-
(2007)
Molecular and Cellular Biochemistry
, vol.304
, Issue.1-2
, pp. 53-60
-
-
Tsubaki, M.1
Kato, C.2
Manno, M.3
Ogaki, M.4
Satou, T.5
Itoh, T.6
Kusunoki, T.7
Tanimori, Y.8
Fujiwara, K.9
Matsuoka, H.10
Nishida, S.11
-
10
-
-
0038386032
-
Macrophage inflammatory protein 1-alpha (MIP-1α) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells
-
DOI 10.1182/blood-2002-08-2383
-
Lentzsch, S.; Gries, M.; Janz, M.; Bargou, R.; Dörken, B.; Mapara, M.Y. Macrophage inflammatory protein 1-alpha (MIP-1 alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells. Blood, 2003, 101, 3568-3573. (Pubitemid 36857943)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3568-3573
-
-
Lentzsch, S.1
Gries, M.2
Janz, M.3
Bargou, R.4
Dorken, B.5
Mapara, M.Y.6
-
11
-
-
0030903039
-
Macrophage inflammatory protein-1α (LD78) expressed in human bone marrow: Its role in regulation of hematopoiesis and osteoclast recruitment
-
Kukita, T.; Nomiyama, H.; Ohmoto, Y.; Kukita, A.; Shuto, T.; Hotokebuchi, T.; Sugioka, Y.; Miura, R.; Iijima, T. Macrophage inflammatory protein-1 alpha (LD78) expressed in human bone marrow: its role in regulation of hematopoiesis and osteoclast recruitment. Lab Invest., 1997, 76, 399-406. (Pubitemid 27157347)
-
(1997)
Laboratory Investigation
, vol.76
, Issue.3
, pp. 399-406
-
-
Kukita, T.1
Nomiyama, H.2
Ohmoto, Y.3
Kukita, A.4
Shuto, T.5
Hotokebuchi, T.6
Sugioka, Y.7
Miura, R.8
Iijima, T.9
-
12
-
-
0028989486
-
Macrophage inflammatory protein-1 alpha and il-8 stimulate the motility but suppress the resorption of isolated rat osteoclasts
-
Fuller, K.; Owens, J.M.; Chambers, T.J. Macrophage inflammatory protein-1 alpha and IL-8 stimulate the motility but suppress the resorption of isolated rat osteoclasts. J. Immunol., 1995, 154, 6065-6072.
-
(1995)
J. Immunol
, vol.154
, pp. 6065-6072
-
-
Fuller, K.1
Owens, J.M.2
Chambers, T.J.3
-
13
-
-
0342322717
-
Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma
-
Choi, S.J.; Cruz, J.C.; Craig, F.; Chung, H.; Devlin, R.D.; Roodman, G.D.; Alsina, M. Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma. Blood, 2000, 96, 671-675. (Pubitemid 30463390)
-
(2000)
Blood
, vol.96
, Issue.2
, pp. 671-675
-
-
Choi, S.J.1
Cruz, J.C.2
Craig, F.3
Chung, H.4
Devlin, R.D.5
Roodman, G.D.6
Alsina, M.7
-
14
-
-
33646838449
-
Mediterranean diet olive oil and cancer
-
Colomer, R.; Menéndez, J.A. Mediterranean diet, olive oil and cancer. Clin. Transl. Oncol., 2006, 8, 15-21.
-
(2006)
Clin. Transl. Oncol
, vol.8
, pp. 15-21
-
-
Colomer, R.1
Menéndez, J.A.2
-
15
-
-
67349201394
-
Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer mcf-7 cells
-
Han, J.; Talorete, T.P.; Yamada, P.; Isoda, H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology, 2009, 59, 45-53.
-
(2009)
Cytotechnology
, vol.59
, pp. 45-53
-
-
Han, J.1
Talorete, T.P.2
Yamada, P.3
Isoda, H.4
-
16
-
-
0033945291
-
Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene
-
DOI 10.1016/S0278-6915(00)00061-2, PII S0278691500000612
-
Owen, R.W.; Mier, W.; Giacosa, A.; Hull, W.E.; Spiegelhalder, B.; Bartsch, H. Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene. Food Chem. Toxicol., 2000, 38, 647-659. (Pubitemid 30447459)
-
(2000)
Food and Chemical Toxicology
, vol.38
, Issue.8
, pp. 647-659
-
-
Owen, R.W.1
Mier, W.2
Giacosa, A.3
Hull, W.E.4
Spiegelhalder, B.5
Bartsch, H.6
-
17
-
-
24344504061
-
Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro
-
DOI 10.1002/ijc.21083
-
Gill, C.I.; Boyd, A.; McDermott, E.; McCann, M.; Servili, M.; Selvaggini, R.; Taticchi, A.; Esposto, S.; Montedoro, G.; McGlynn, H.; Rowland, I. Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro. Int. J. Cancer, 2005, 117, 1-7. (Pubitemid 41262753)
-
(2005)
International Journal of Cancer
, vol.117
, Issue.1
, pp. 1-7
-
-
Gill, C.I.R.1
Boyd, A.2
McDermott, E.3
McCann, M.4
Servili, M.5
Selvaggini, R.6
Taticchi, A.7
Esposto, S.8
Montedoro, G.9
McGlynn, H.10
Rowland, I.11
-
18
-
-
24344452961
-
Ibuprofen-like activity in extra-virgin olive oil
-
DOI 10.1038/437045a, PII 437045
-
Beauchamp, G.K.; Keast, R.S.; Morel, D.; Lin, J.; Pika, J.; Han, Q.; Lee, C.H.; Smith, A.B.; Breslin, P.A. Phytochemistry: ibuprofenlike activity in extra-virgin olive oil. Nature, 2005, 437, 45-46. (Pubitemid 41613421)
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 45-46
-
-
Beauchamp, G.K.1
Keast, R.S.J.2
Morel, D.3
Lin, J.4
Pika, J.5
Han, Q.6
Lee, C.-H.7
Smith, A.B.8
Breslin, P.A.S.9
-
19
-
-
70349241517
-
Alzheimer'sassociated abeta oligomers show altered structure immunoreactivity and synaptotoxicity with low doses of oleocanthal
-
Pitt, J.; Roth, W.; Lacor, P.; Smith, A.B. 3rd, Blankenship, M.; Velasco, P.; De Felice, F.; Breslin, P.; Klein, W.L. Alzheimer'sassociated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol. Appl. Pharmacol., 2009, 240, 189-197.
-
(2009)
Toxicol. Appl. Pharmacol
, vol.240
, pp. 189-197
-
-
Pitt, J.1
Roth, W.2
Lacor, P.3
Smith III, A.B.4
Blankenship, M.5
Velasco, P.6
De Felice, F.7
Breslin, P.8
Klein, W.L.9
-
20
-
-
77952921830
-
Effect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell line
-
Iacono, A.; Gómez, R.; Sperry, J.; Conde, J.; Bianco, G.; Meli, R.; Gómez-Reino, J.J.; Smith, A.B. 3rd; Gualillo, O. Effect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell line. Arthritis Rheum., 2010, 62, 1675-1682.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1675-1682
-
-
Iacono, A.1
Gómez, R.2
Sperry, J.3
Conde, J.4
Bianco, G.5
Meli, R.6
Gómez-Reino, J.J.7
Smith III, A.B.8
Gualillo, O.9
-
21
-
-
84869504888
-
Further evidence for the anti-inflammatory activity of oleocanthal: Inhibition of mip-1 and il-6 in j774 macrophages and in atdc5 chondrocytes
-
Scotece, M.; Gómez, R.; Conde, J.; Lopez, V.; Gómez-Reino, J.J.; Lago, F.; Smith, A.B., 3rd.; Gualillo, O. Further evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1 and IL-6 in J774 macrophages and in ATDC5 chondrocytes. Life Sci., 2012, 91 (23-24), 1229-1235.
-
(2012)
Life Sci
, vol.91
, Issue.23-24
, pp. 1229-1235
-
-
Scotece, M.1
Gómez, R.2
Conde, J.3
Lopez, V.4
Gómez-Reino, J.J.5
Lago, F.6
Smith III, A.B.7
Gualillo, O.8
-
22
-
-
41149115987
-
Secondary necrosis in multicellular animals: An outcome of apoptosis with pathogenic implications
-
Silva, M.T.; do Vale, A.; dos Santos, N.M. Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications. Apoptosis., 2008, 13 (4), 463-482.
-
(2008)
Apoptosis
, vol.13
, Issue.4
, pp. 463-482
-
-
Silva, M.T.1
Do Vale, A.2
Dos Santos, N.M.3
-
23
-
-
79960269049
-
A novel role for ccl3 (mip-1alpha) in myelomainduced bone disease via osteocalcin downregulation and inhibition of osteoblast function
-
Vallet, S.; Pozzi, S.; Patel, K.; Vaghela, N.; Fulciniti, M.T.; Veiby, P.; Hideshima, T.; Santo, L.; Cirstea, D.; Scadden, D.T.; Anderson, K.C.; Raje, N. A novel role for CCL3 (MIP-1alpha) in myelomainduced bone disease via osteocalcin downregulation and inhibition of osteoblast function. Leukemia, 2011, 25, 1174-1181.
-
(2011)
Leukemia
, vol.25
, pp. 1174-1181
-
-
Vallet, S.1
Pozzi, S.2
Patel, K.3
Vaghela, N.4
Fulciniti, M.T.5
Veiby, P.6
Hideshima, T.7
Santo, L.8
Cirstea, D.9
Scadden, D.T.10
Anderson, K.C.11
Raje, N.12
-
24
-
-
0035525792
-
The akt kinase is activated in multiple myeloma tumor cells
-
Hsu, J.; Shi, Y.; Krajewski, S.; Renner, S.; Fisher, M.; Reed, J.C.; Franke, T.F.; Lichtenstein, A. The AKT kinase is activated in multiple myeloma tumor cells. Blood, 2001, 98, 2853-2855.
-
(2001)
Blood
, vol.98
, pp. 2853-2855
-
-
Hsu, J.1
Shi, Y.2
Krajewski, S.3
Renner, S.4
Fisher, M.5
Reed, J.C.6
Franke, T.F.7
Lichtenstein, A.8
-
25
-
-
0035207110
-
The role of nuclear factor-κB in the biology and treatment of multiple myeloma
-
Berenson, J.R.; Ma, H.M.; Vescio, R. The role of nuclear factorkappaB in the biology and treatment of multiple myeloma. Semin. Oncol., 2001, 28, 626-633. (Pubitemid 33138161)
-
(2001)
Seminars in Oncology
, vol.28
, Issue.6
, pp. 626-633
-
-
Berenson, J.R.1
Ma, H.M.2
Vescio, R.3
-
26
-
-
0037305821
-
Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
-
DOI 10.1182/blood-2002-05-1320
-
Bharti, A.C.; Donato, N.; Singh, S.; Aggarwal, B.B. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood, 2003, 101, 1053-1062. (Pubitemid 36139379)
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 1053-1062
-
-
Bharti, A.C.1
Donato, N.2
Singh, S.3
Aggarwal, B.B.4
-
27
-
-
1542398801
-
Downmodulation of ERK protein kinase activity inihibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis
-
DOI 10.1038/sj.leu.2403269
-
Giuliani, N.; Lunghi, P.; Morandi, F.; Colla, S.; Bonomini, S.; Hojden, M.; Rizzoli, V.; Bonati, A. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Leukemia, 2004, 18, 628-635. (Pubitemid 38425880)
-
(2004)
Leukemia
, vol.18
, Issue.3
, pp. 628-635
-
-
Giuliani, N.1
Lunghi, P.2
Morandi, F.3
Colla, S.4
Bonomini, S.5
Hojden, M.6
Rizzoli, V.7
Bonati, A.8
-
28
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
DOI 10.1016/S1074-7613(00)80011-4
-
Catlett-Falcone, R.; Landowski, T.H.; Oshiro, M.M.; Turkson, J.; Levitzki, A.; Savino, R.; Ciliberto, G.; Moscinski, L.; Fernández-Luna, J.L.; Nuñez, G.; Dalton, W.S.; Jove, R. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity, 1999, 10, 105-115. (Pubitemid 29077388)
-
(1999)
Immunity
, vol.10
, Issue.1
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
Ciliberto, G.7
Moscinski, L.8
Fernandez-Luna, J.L.9
Nunez, G.10
Dalton, W.S.11
Jove, R.12
|