메뉴 건너뛰기




Volumn 8, Issue JUN, 2017, Pages

Applying precision medicine and immunotherapy advances from oncology to host-directed therapies for infectious diseases

Author keywords

HDT; Immuno oncology; Immunometabolism; Infectious diseases; Precision medicine; Tuberculosis

Indexed keywords

CHEMOKINE; CYTOKINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; HYPOXIA INDUCIBLE FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; SIRTUIN;

EID: 85021778908     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00688     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 84924655284 scopus 로고    scopus 로고
    • Geneva, Switzerland: World Health Organization
    • Antimicrobial Resistance: Global Report on Surveillance. Geneva, Switzerland: World Health Organization (2014). Available from: http://apps.who.int/iris/bitstream/10665/112642/1/9789241564748_eng.pdf?ua=1
    • (2014) Global Report on Surveillance.
  • 2
    • 84925703181 scopus 로고    scopus 로고
    • Advancing host-directed therapy for tuberculosis
    • Wallis RS, Hafner R. Advancing host-directed therapy for tuberculosis. Nat Rev Immunol (2015) 15:255-63. doi:10.1038/nri3813
    • (2015) Nat Rev Immunol , vol.15 , pp. 255-263
    • Wallis, R.S.1    Hafner, R.2
  • 3
    • 84960422665 scopus 로고    scopus 로고
    • The basis of oncoimmunology
    • Palucka AK, Coussens LM. The basis of oncoimmunology. Cell (2016) 164:1233-47. doi:10.1016/j.cell.2016.01.049
    • (2016) Cell , vol.164 , pp. 1233-1247
    • Palucka, A.K.1    Coussens, L.M.2
  • 4
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med (2015) 372:793-5. doi:10.1056/NEJMp1500523
    • (2015) N Engl J Med , vol.372 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 5
    • 79251527210 scopus 로고    scopus 로고
    • Helicobacter pylori activation of PARP-1: usurping a versatile regulator of host cellular health
    • Nossa CW, Blanke SR. Helicobacter pylori activation of PARP-1: usurping a versatile regulator of host cellular health. Gut Microbes (2010) 1:373-8. doi:10.4161/gmic.1.6.13572
    • (2010) Gut Microbes , vol.1 , pp. 373-378
    • Nossa, C.W.1    Blanke, S.R.2
  • 6
    • 77951220203 scopus 로고    scopus 로고
    • Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelaA pathway for up-regulation of cytokine expression in cardiomyocytes
    • Ba X, Gupta S, Davidson M, Garg NJ. Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelaA pathway for up-regulation of cytokine expression in cardiomyocytes. J Biol Chem (2010) 285:11596-606. doi:10.1074/jbc.M109.076984
    • (2010) J Biol Chem , vol.285 , pp. 11596-11606
    • Ba, X.1    Gupta, S.2    Davidson, M.3    Garg, N.J.4
  • 7
    • 84969533827 scopus 로고    scopus 로고
    • A lasting impression: epigenetic memory of bacterial infections
    • Pereira JM, Harmon MA, Cossart P. A lasting impression: epigenetic memory of bacterial infections. Cell Host Microbe (2016) 19:579-82. doi:10.1016/j.chom.2016.04.012
    • (2016) Cell Host Microbe , vol.19 , pp. 579-582
    • Pereira, J.M.1    Harmon, M.A.2    Cossart, P.3
  • 8
    • 84876758617 scopus 로고    scopus 로고
    • Metabolic pathways in immune cell activation and quiescence
    • Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity (2013) 38:633-43. doi:10.1016/j.immuni.2013.04.005
    • (2013) Immunity , vol.38 , pp. 633-643
    • Pearce, E.L.1    Pearce, E.J.2
  • 9
    • 84978148203 scopus 로고    scopus 로고
    • A guide to immunometabolism for immunologists
    • O'Neil LA, Kishton RJ, Rathmell J. A guide to immunometabolism for immunologists. Nat Rev Immunol (2016) 16:553-65. doi:10.1038/nri.2016.70
    • (2016) Nat Rev Immunol , vol.16 , pp. 553-565
    • O'Neil, L.A.1    Kishton, R.J.2    Rathmell, J.3
  • 11
    • 84975063534 scopus 로고    scopus 로고
    • Metabolic reprogramming of host cells by virulent Francisella tularensis for optimal replication and modulation of inflammation
    • Wyatt EV, Diaz K, Griffin AJ, Rasmussen JA, Crane DD, Jones BD, et al. Metabolic reprogramming of host cells by virulent Francisella tularensis for optimal replication and modulation of inflammation. J Immunol (2016) 196:4227-36. doi:10.4049/jimmunol.1502456
    • (2016) J Immunol , vol.196 , pp. 4227-4236
    • Wyatt, E.V.1    Diaz, K.2    Griffin, A.J.3    Rasmussen, J.A.4    Crane, D.D.5    Jones, B.D.6
  • 12
    • 84867606677 scopus 로고    scopus 로고
    • Psuedomonas aeruginosa alkyl quinolones repress hypoxia-inducibe factor 1 (HIF-1) signaling through HIF-1a degradation
    • Legendre C, Reen FJ, Mooij MJ, McGlacken GP, Adams C, O'Gara F. Psuedomonas aeruginosa alkyl quinolones repress hypoxia-inducibe factor 1 (HIF-1) signaling through HIF-1a degradation. Infect Immun (2012) 80:3985-92. doi:10.1128/IAI.00554-12
    • (2012) Infect Immun , vol.80 , pp. 3985-3992
    • Legendre, C.1    Reen, F.J.2    Mooij, M.J.3    McGlacken, G.P.4    Adams, C.5    O'Gara, F.6
  • 13
    • 84940437862 scopus 로고    scopus 로고
    • The Streptococcus pyogenes NAD+glycohydrolase modulates epithelial cell PARylation and HMGB1 release
    • Chandrasekaran S, Cpaaron MG. The Streptococcus pyogenes NAD+glycohydrolase modulates epithelial cell PARylation and HMGB1 release. Cell Microbiol (2015) 17:1376-90. doi:10.1111/cmi.12442
    • (2015) Cell Microbiol , vol.17 , pp. 1376-1390
    • Chandrasekaran, S.1    Cpaaron, M.G.2
  • 15
    • 84959051815 scopus 로고    scopus 로고
    • Metabolic adaptations of intracellular bacterial pathogens and their mammalian host cells during infection ("Pathometabolism")
    • Eisenreich W, Heesemann J, Rudel T, Goebel W. Metabolic adaptations of intracellular bacterial pathogens and their mammalian host cells during infection ("Pathometabolism"). Microbiol Spectr (2015) 3(3):1-24. doi:10.1128/microbiolspec.MBP-0002-2014
    • (2015) Microbiol Spectr , vol.3 , Issue.3 , pp. 1-24
    • Eisenreich, W.1    Heesemann, J.2    Rudel, T.3    Goebel, W.4
  • 16
    • 84926480675 scopus 로고    scopus 로고
    • Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis
    • Moreira D, Rodrigues V, Abengozar M, Rivas L, Rial E, Laforge M, et al. Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis. PLoS Pathog (2015) 11:e1004684. doi:10.1371/journal.ppat.1004684
    • (2015) PLoS Pathog , vol.11
    • Moreira, D.1    Rodrigues, V.2    Abengozar, M.3    Rivas, L.4    Rial, E.5    Laforge, M.6
  • 17
    • 84977647129 scopus 로고    scopus 로고
    • Hypoxia inducible factor 1a: a critical factor the immune response to pathogens and Leishmania
    • Charpentier T, Hammami A, Stäger S. Hypoxia inducible factor 1a: a critical factor the immune response to pathogens and Leishmania. Cell Immunol (2016) 309:42-9. doi:10.1016/j.cellimm.2016.06.002
    • (2016) Cell Immunol , vol.309 , pp. 42-49
    • Charpentier, T.1    Hammami, A.2    Stäger, S.3
  • 18
    • 84938897054 scopus 로고    scopus 로고
    • Tuberculosis secretory protein ESAT-6 induces metabolic flux perturbations to drive foamy macrophage differentiation.
    • Singh V, Kaur C, Chaudhary VK, Rao KV, Chatterjee S. M. Tuberculosis secretory protein ESAT-6 induces metabolic flux perturbations to drive foamy macrophage differentiation. Sci Rep (2015) 5:12906. doi:10.1038/srep12906
    • (2015) Sci Rep , vol.5 , pp. 12906
    • Singh, V.1    Kaur, C.2    Chaudhary, V.K.3    Rao, K.V.4    Chatterjee, S.M.5
  • 20
    • 84983656454 scopus 로고    scopus 로고
    • Is there potential for repurposing statins as novel antimicrobials
    • Hennessy E, Adams C, Reen FJ, O'Gara F. Is there potential for repurposing statins as novel antimicrobials. Antimicrob Agents Chemother (2016) 60:5111-21. doi:10.1128/AAC.00192-16
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 5111-5121
    • Hennessy, E.1    Adams, C.2    Reen, F.J.3    O'Gara, F.4
  • 21
    • 84988027218 scopus 로고    scopus 로고
    • Topical simivastatin as host-directed therapy against severity of cutaneous leishmaniasis in mice
    • Parihar SP, Hartley MA, Hurdayal R, Guler R, Brombacher F. Topical simivastatin as host-directed therapy against severity of cutaneous leishmaniasis in mice. Sci Rep (2016) 6:33458. doi:10.1038/srep33458
    • (2016) Sci Rep , vol.6 , pp. 33458
    • Parihar, S.P.1    Hartley, M.A.2    Hurdayal, R.3    Guler, R.4    Brombacher, F.5
  • 22
    • 85009385398 scopus 로고    scopus 로고
    • Adjunct strategies for tuberculosis vaccines: modulating key immune cell regulatory mechanisms to potentiate vaccination
    • Jayashankar L, Hafner R. Adjunct strategies for tuberculosis vaccines: modulating key immune cell regulatory mechanisms to potentiate vaccination. Front Immunol (2016) 7:577. doi:10.3389/fimmu.2016.00577
    • (2016) Front Immunol , vol.7 , pp. 577
    • Jayashankar, L.1    Hafner, R.2
  • 23
    • 85003874481 scopus 로고    scopus 로고
    • Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity
    • Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, et al. Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity. Cell Metab (2016) 24:807-19. doi:10.1016/j.cmet.2016.10.008
    • (2016) Cell Metab , vol.24 , pp. 807-819
    • Arts, R.J.1    Novakovic, B.2    Ter Horst, R.3    Carvalho, A.4    Bekkering, S.5    Lachmandas, E.6
  • 25
    • 84943380478 scopus 로고    scopus 로고
    • Immune cell regulatory pathways unexplored as host-directed therapeutic targets for Mycobacterium tuberculosis: an opportunity to apply precision medicine innovations to infectious diseases
    • Mahon RN, Hafner R. Immune cell regulatory pathways unexplored as host-directed therapeutic targets for Mycobacterium tuberculosis: an opportunity to apply precision medicine innovations to infectious diseases. Clin Infect Dis (2015) 61(Suppl 3):S200-16. doi:10.1093/cid/civ621
    • (2015) Clin Infect Dis , vol.61 , pp. S200-S216
    • Mahon, R.N.1    Hafner, R.2
  • 26
    • 84964607369 scopus 로고    scopus 로고
    • The commonalities in bacterial effector inhibition of apoptosis
    • Robinson KS, Aw R. The commonalities in bacterial effector inhibition of apoptosis. Trends Microbiol (2016) 24:665-80. doi:10.1016/j.tim.2016.04.002
    • (2016) Trends Microbiol , vol.24 , pp. 665-680
    • Robinson, K.S.1    Aw, R.2
  • 27
    • 84954484374 scopus 로고    scopus 로고
    • Regulated necrosis: disease relevance and therapeutic opportunities
    • Conrad M, Angeli JP, Vandenabeele P, Stockwell BR. Regulated necrosis: disease relevance and therapeutic opportunities. Nat Rev Drug Discov (2016) 15:348-66. doi:10.1038/nrd.2015.6
    • (2016) Nat Rev Drug Discov , vol.15 , pp. 348-366
    • Conrad, M.1    Angeli, J.P.2    Vandenabeele, P.3    Stockwell, B.R.4
  • 29
    • 84997706268 scopus 로고    scopus 로고
    • Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8+ T cell exhaustion
    • Bengsch B, Johsnon AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, et al. Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8+ T cell exhaustion. Immunity (2016) 45:358-73. doi:10.1016/j.immuni.2016.07.008
    • (2016) Immunity , vol.45 , pp. 358-373
    • Bengsch, B.1    Johsnon, A.L.2    Kurachi, M.3    Odorizzi, P.M.4    Pauken, K.E.5    Attanasio, J.6
  • 30
    • 84941796489 scopus 로고    scopus 로고
    • A2aR antagonists: next generation checkpoint blockade for cancer immunotherapy
    • Leone RD, Lo YC, Powell JD. A2aR antagonists: next generation checkpoint blockade for cancer immunotherapy. Comput Struct Biotechnol J (2015) 13:265-72. doi:10.1016/j.csbj.2015.03.008
    • (2015) Comput Struct Biotechnol J , vol.13 , pp. 265-272
    • Leone, R.D.1    Lo, Y.C.2    Powell, J.D.3
  • 31
    • 84966762527 scopus 로고    scopus 로고
    • Costimulatory and coinhibitory receptor pathways in infectious disease
    • Attanasio J, Wherry EJ. Costimulatory and coinhibitory receptor pathways in infectious disease. Immunity (2016) 44:1052-68. doi:10.1016/j.immuni.2016.04.022
    • (2016) Immunity , vol.44 , pp. 1052-1068
    • Attanasio, J.1    Wherry, E.J.2
  • 32
    • 79251578015 scopus 로고    scopus 로고
    • CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition
    • Barber DL, Mayer-Barber KD, Feng CG, Sharpe AH, Sher A. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition. J Immunol (2011) 186:1598-607. doi:10.4049/jimmunol.1003304
    • (2011) J Immunol , vol.186 , pp. 1598-1607
    • Barber, D.L.1    Mayer-Barber, K.D.2    Feng, C.G.3    Sharpe, A.H.4    Sher, A.5
  • 33
    • 84880944556 scopus 로고    scopus 로고
    • Inhibiting the programmed death 1 pathway rescues Mycobacterium tuberculosis-specific interferon ?-producing T cells from apoptosis in patients with pulmonary tuberculosis
    • Singh A, Mohan A, Dey AB, Mitra DK. Inhibiting the programmed death 1 pathway rescues Mycobacterium tuberculosis-specific interferon ?-producing T cells from apoptosis in patients with pulmonary tuberculosis. J Infect Dis (2013) 208:603-15. doi:10.1093/infdis/jit206
    • (2013) J Infect Dis , vol.208 , pp. 603-615
    • Singh, A.1    Mohan, A.2    Dey, A.B.3    Mitra, D.K.4
  • 34
    • 85002661263 scopus 로고    scopus 로고
    • Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity
    • Karunarathne DS, Horne-Debets JM, Huang JX, Faleiro R, Leow CY, Amante F, et al. Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity. Immunity (2016) 45:333-45. doi:10.1016/j.immuni.2016.07.017
    • (2016) Immunity , vol.45 , pp. 333-345
    • Karunarathne, D.S.1    Horne-Debets, J.M.2    Huang, J.X.3    Faleiro, R.4    Leow, C.Y.5    Amante, F.6
  • 35
    • 84857561919 scopus 로고    scopus 로고
    • OX40 ligands fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection
    • Snelgrove RJ, Cornere MM, Edwards L, Dagg B, Keeble J, Rodgers A, et al. OX40 ligands fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection. J Infect Dis (2012) 205:975-83. doi:10.1093/infdis/jir868
    • (2012) J Infect Dis , vol.205 , pp. 975-983
    • Snelgrove, R.J.1    Cornere, M.M.2    Edwards, L.3    Dagg, B.4    Keeble, J.5    Rodgers, A.6
  • 36
    • 84959542771 scopus 로고    scopus 로고
    • The nature of myeloid-derived suppressor cells in the tumor microenvironment
    • Kumar V, Patel S, Tcyganov E, Gabrilovich DI. The nature of myeloid-derived suppressor cells in the tumor microenvironment. Trends Immunol (2016) 37:208-20. doi:10.1016/j.it.2016.01.004
    • (2016) Trends Immunol , vol.37 , pp. 208-220
    • Kumar, V.1    Patel, S.2    Tcyganov, E.3    Gabrilovich, D.I.4
  • 37
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: mechanisms of differentiation and function
    • Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol (2012) 30:531-64. doi:10.1146/annurev.immunol.25.022106.141623
    • (2012) Annu Rev Immunol , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.F.2    Rudensky, A.Y.3
  • 39
    • 84904549329 scopus 로고    scopus 로고
    • Parallels between cancer and infectious disease
    • Hotchkiss RS, Moldawer LL. Parallels between cancer and infectious disease. N Engl J Med (2014) 371:380-3. doi:10.1056/NEJMcibr1404664
    • (2014) N Engl J Med , vol.371 , pp. 380-383
    • Hotchkiss, R.S.1    Moldawer, L.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.