Metabolic reprogramming of host cells by virulent francisella tularensis for optimal replication and modulation of inflammation

Journal of Immunology

Volumn 196, Issue 10, 2016, Pages 4227-4236

  Wyatt, Elliott V ^a   Diaz, Karina ^a,c   Griffin, Amanda J ^a   Rasmussen, Jed A ^b,d   Crane, Deborah D ^a   Jones, Bradley D ^b   Bosio, Catharine M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d Snow College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; 6 PHOSPHOFRUCTO 2 KINASE; CYTOKINE; HIF1A PROTEIN, MOUSE; PFKFB3 PROTEIN, MOUSE;

AEROBIC GLYCOLYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CAPSULE; BACTERIAL GENE; BACTERIAL REPRODUCTION; BACTERIAL VIRULENCE; BONE MARROW DERIVED MACROPHAGE; CELL REPROGRAMMING TECHNIQUE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; DOWN REGULATION; FRANCISELLA TULARENSIS; GLYCOLYSIS; HOST CELL; HOST PATHOGEN INTERACTION; HOST RESISTANCE; INFLAMMATION; MACROPHAGE ACTIVATION; METABOLIC REPROGRAMMING; MOUSE; NONHUMAN; PFKFB3 GENE; PRIORITY JOURNAL; TULAREMIA; UPREGULATION; ANIMAL; C57BL MOUSE; IMMUNOLOGY; MACROPHAGE; METABOLISM; NUCLEAR REPROGRAMMING; PATHOGENICITY; VIRULENCE;

ANIMALS; BACTERIAL CAPSULES; CELLULAR REPROGRAMMING; CYTOKINES; DOWN-REGULATION; FRANCISELLA TULARENSIS; GLYCOLYSIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; PHOSPHOFRUCTOKINASE-2; TULAREMIA; VIRULENCE;

EID: 84975063534     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502456     Document Type: Article

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