Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4+ T Cell Immunity

Immunity

Volumn 45, Issue 2, 2016, Pages 333-345

  Karunarathne, Deshapriya S ^a   Horne Debets, Joshua M ^a   Huang, Johnny X ^b   Faleiro, Rebecca ^a   Leow, Chiuan Yee ^a   Amante, Fiona ^a   Watkins, Thomas S ^a   Miles, John J ^a   Dwyer, Patrick J ^c   Stacey, Katryn J ^b   Yarski, Michael ^d   Poh, Chek Meng ^e,f   Lee, Jason S ^a   Cooper, Matthew A ^b   Rénia, Laurent ^e,f   Richard, Derek ^c   McCarthy, James S ^a   Sharpe, Arlene H ^g   Wykes, Michelle N ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^d Millennium Science   (Australia)

^e AGENCY FOR SCIENCE   (Singapore)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; IMMUNOGLOBULIN G; INDUCIBLE CO STIMULATOR; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 LIGAND 2 MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN; PYRIMETHAMINE; UNCLASSIFIED DRUG; ADAMANTANE; ANTIMALARIAL AGENT; DSM265; OZ 439; PDCD1 PROTEIN, HUMAN; PDCD1LG2 PROTEIN, MOUSE; PEROXIDE; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; IMMUNOREGULATION; MALARIA; MOUSE; NONHUMAN; PARASITE CONTROL; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TH1 CELL; ADULT; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL CULTURE; CLINICAL TRIAL (TOPIC); DENDRITIC CELL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MALARIA, FALCIPARUM; MALE; METABOLISM; MIDDLE AGED; PARASITEMIA; PARASITOLOGY; PLASMODIUM FALCIPARUM; YOUNG ADULT;

ADAMANTANE; ADULT; ANIMALS; ANTIGENS, CD274; ANTIMALARIALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CLINICAL TRIALS AS TOPIC; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNITY, CELLULAR; LYMPHOCYTE ACTIVATION; MALARIA, FALCIPARUM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; PARASITEMIA; PEROXIDES; PLASMODIUM FALCIPARUM; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROGRAMMED CELL DEATH 1 RECEPTOR; PYRIMIDINES; TRIAZOLES; YOUNG ADULT;

EID: 85002661263     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.07.017     Document Type: Article

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