Immunometabolic Pathways in BCG-Induced Trained Immunity

Cell Reports

Volumn 17, Issue 10, 2016, Pages 2562-2571

  Arts, Rob J W ^a   Carvalho, Agostinho ^b,c   La Rocca, Claudia ^d   Palma, Carla ^e   Rodrigues, Fernando ^b,c   Silvestre, Ricardo ^b,c   Kleinnijenhuis, Johanneke ^a   Lachmandas, Ekta ^a   Gonçalves, Luís G ^f   Belinha, Ana ^b,c   Cunha, Cristina ^b,c   Oosting, Marije ^a   Joosten, Leo A B ^a   Matarese, Giuseppe ^d,g   van Crevel, Reinout ^a   Netea, Mihai G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF MINHO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d CNR   (Italy)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

BCG; epigenetics; glycolysis; immunometabolism; monocytes; trained immunity

Indexed keywords

BCG VACCINE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; HISTONE H3; HISTONE H3K4; HISTONE H3K9; LACTIC ACID; MALIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BCG VACCINATION; CELL METABOLISM; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DRUG DOSE INCREASE; EPIGENETICS; FEMALE; GENE EXPRESSION REGULATION; GENETIC VARIATION; GLUCOSE METABOLISM; GLYCOLYSIS; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MALE; MONOCYTE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TRAINED IMMUNITY; TUBERCULOSIS; UPREGULATION; ANIMAL; GENETIC EPIGENESIS; GENETICS; HISTONE CODE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MICROBIOLOGY;

ANIMALS; BCG VACCINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; EPIGENESIS, GENETIC; GLYCOLYSIS; HISTONE CODE; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; MICE; MONOCYTES; TUBERCULOSIS;

EID: 85002577534     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.11.011     Document Type: Article

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