메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; GLUCOSE TRANSPORTER 1;

EID: 84938897054     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep12906     Document Type: Article
Times cited : (46)

References (22)
  • 1
    • 77049286017 scopus 로고
    • Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro
    • Bloch, H. & Segal, W. Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro. Journal of bacteriology 72, 132-141 (1956).
    • (1956) Journal of Bacteriology , vol.72 , pp. 132-141
    • Bloch, H.1    Segal, W.2
  • 2
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole, S. T. et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544, doi: 10.1038/31159 (1998).
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1
  • 3
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. & Altare, F. Foamy macrophages and the progression of the human tuberculosis granuloma. Nature immunology 10, 943-948, doi: 10.1038/ni.1781 (2009).
    • (2009) Nature Immunology , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.J.2    Kim, M.J.3    Allain, S.4    Altare, F.5
  • 4
    • 84869176200 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype
    • Singh, V. et al. Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype. Cell host & microbe 12, 669-681, doi: 10.1016/j.chom.2012.09.012 (2012).
    • (2012) Cell Host & Microbe , vol.12 , pp. 669-681
    • Singh, V.1
  • 5
    • 57149096869 scopus 로고    scopus 로고
    • Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. Tuberculosis persistence
    • Peyron, P. et al. Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS pathogens 4, e1000204, doi: 10.1371/journal.ppat.1000204 (2008).
    • (2008) PLoS Pathogens , vol.4
    • Peyron, P.1
  • 6
    • 34250742727 scopus 로고    scopus 로고
    • Pathology of postprimary tuberculosis in humans and mice: Contradiction of long-held beliefs
    • Hunter, R. L., Jagannath, C. & Actor, J. K. Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs. Tuberculosis 87, 267-278, doi: 10.1016/j.tube.2006.11.003 (2007).
    • (2007) Tuberculosis , vol.87 , pp. 267-278
    • Hunter, R.L.1    Jagannath, C.2    Actor, J.K.3
  • 7
    • 57349164051 scopus 로고    scopus 로고
    • Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole
    • Smith, J. et al. Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole. Infection and immunity 76, 5478-5487, doi: 10.1128/IAI.00614-08 (2008).
    • (2008) Infection and Immunity , vol.76 , pp. 5478-5487
    • Smith, J.1
  • 8
    • 34250716965 scopus 로고    scopus 로고
    • Tuberculosis and M. Leprae translocate from the phagolysosome to the cytosol in myeloid cells
    • Van Der Wel, N. et al. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129, 1287-1298, doi: 10.1016/j.cell.2007.05.059 (2007).
    • (2007) Cell , vol.129 , pp. 1287-1298
    • Van Der Wel1    Et Al. M, N.2
  • 9
    • 72949091846 scopus 로고    scopus 로고
    • Potential role for ESAT6 in dissemination of M. Tuberculosis via human lung epithelial cells
    • Kinhikar, A. G. et al. Potential role for ESAT6 in dissemination of M. tuberculosis via human lung epithelial cells. Molecular microbiology 75, 92-106, doi: 10.1111/j.1365-2958.2009.06959.x (2010).
    • (2010) Molecular Microbiology , vol.75 , pp. 92-106
    • Kinhikar, A.G.1
  • 10
    • 34249012130 scopus 로고    scopus 로고
    • Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
    • Pathak, S. K. et al. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nature immunology 8, 610-618, doi: 10.1038/ni1468 (2007).
    • (2007) Nature Immunology , vol.8 , pp. 610-618
    • Pathak, S.K.1
  • 11
    • 60049091769 scopus 로고    scopus 로고
    • ESX/type VII secretion systems and their role in host-pathogen interaction
    • Simeone, R., Bottai, D. & Brosch, R. ESX/type VII secretion systems and their role in host-pathogen interaction. Current opinion in microbiology 12, 4-10, doi: 10.1016/j.mib.2008.11.003 (2009).
    • (2009) Current Opinion in Microbiology , vol.12 , pp. 4-10
    • Simeone, R.1    Bottai, D.2    Brosch, R.3
  • 12
    • 0018864840 scopus 로고
    • Regulation of hepatic fatty acid oxidation and ketone body production
    • McGarry, J. D. & Foster, D. W. Regulation of hepatic fatty acid oxidation and ketone body production. Annual review of biochemistry 49, 395-420, doi: 10.1146/annurev.bi.49.070180.002143 (1980).
    • (1980) Annual Review of Biochemistry , vol.49 , pp. 395-420
    • McGarry, J.D.1    Foster, D.W.2
  • 13
    • 84905367555 scopus 로고    scopus 로고
    • Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage
    • Mehrotra, P. et al. Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage. PLoS pathogens 10, e1004265, doi: 10.1371/journal.ppat.1004265 (2014).
    • (2014) PLoS Pathogens , vol.10
    • Mehrotra, P.1
  • 14
    • 0742289564 scopus 로고    scopus 로고
    • Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: A role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation
    • Fu, Y., Maianu, L., Melbert, B. R. & Garvey, W. T. Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation. Blood cells, molecules & diseases 32, 182-190 (2004).
    • (2004) Blood Cells, Molecules & Diseases , vol.32 , pp. 182-190
    • Fu, Y.1    Maianu, L.2    Melbert, B.R.3    Garvey, W.T.4
  • 15
    • 0020060920 scopus 로고
    • Role of free oxaloacetate in ketogenesis. Derivation from the direct measurement of mitochondrial [3-hydroxybutyrate]/[acetoacetate] ratio in hepatocytes
    • Siess, E. A., Kientsch-Engel, R. I. & Wieland, O. H. Role of free oxaloacetate in ketogenesis. Derivation from the direct measurement of mitochondrial [3-hydroxybutyrate]/[acetoacetate] ratio in hepatocytes. European journal of biochemistry/FEBS 121, 493-499 (1982).
    • (1982) European Journal of Biochemistry/FEBS , vol.121 , pp. 493-499
    • Siess, E.A.1    Kientsch-Engel, R.I.2    Wieland, O.H.3
  • 16
    • 80053922625 scopus 로고    scopus 로고
    • Metabolic flux and the regulation of mammalian cell growth
    • Locasale, J. W. & Cantley, L. C. Metabolic flux and the regulation of mammalian cell growth. Cell metabolism 14, 443-451, doi: 10.1016/j.cmet.2011.07.014 (2011).
    • (2011) Cell Metabolism , vol.14 , pp. 443-451
    • Locasale, J.W.1    Cantley, L.C.2
  • 17
    • 85036348092 scopus 로고    scopus 로고
    • Interaction of Mycobacterium tuberculosis ESAT-6 protein with ADAM9 protein
    • Liang, H. & Chen, A. Interaction of Mycobacterium tuberculosis ESAT-6 protein with ADAM9 protein. African Journal of Microbiology Research 5, 919-923 (2011).
    • (2011) African Journal of Microbiology Research , vol.5 , pp. 919-923
    • Liang, H.1    Chen, A.2
  • 19
    • 84908312950 scopus 로고    scopus 로고
    • The ESAT-6 Protein of Mycobacterium tuberculosis Interacts with Beta-2-Microglobulin (beta2M) Affecting Antigen Presentation Function of Macrophage
    • Sreejit, G. et al. The ESAT-6 Protein of Mycobacterium tuberculosis Interacts with Beta-2-Microglobulin (beta2M) Affecting Antigen Presentation Function of Macrophage. PLoS pathogens 10, e1004446, doi: 10.1371/journal.ppat.1004446 (2014).
    • (2014) PLoS Pathogens , vol.10
    • Sreejit, G.1
  • 20
    • 26044432799 scopus 로고    scopus 로고
    • Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis
    • Kulshrestha, A. et al. Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis. Protein Expr Purif 44, 75-85 (2005).
    • (2005) Protein Expr Purif , vol.44 , pp. 75-85
    • Kulshrestha, A.1
  • 21
    • 34848889259 scopus 로고    scopus 로고
    • The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra
    • Shilov, I. V. et al. The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra. Molecular & cellular proteomics : MCP 6, 1638-1655, doi: 10.1074/ mcp.T600050-MCP200 (2007).
    • (2007) Molecular & Cellular Proteomics : MCP , vol.6 , pp. 1638-1655
    • Shilov, I.V.1
  • 22
    • 0037277179 scopus 로고    scopus 로고
    • Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: The yeast proteome
    • Peng, J., Elias, J. E., Thoreen, C. C., Licklider, L. J. & Gygi, S. P. Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome. Journal of proteome research 2, 43-50 (2003).
    • (2003) Journal of Proteome Research , vol.2 , pp. 43-50
    • Peng, J.1    Elias, J.E.2    Thoreen, C.C.3    Licklider, L.J.4    Gygi, S.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.