DOCK8 deficiency: Insights into pathophysiology, clinical features and management

Clinical Immunology

Volumn 181, Issue , 2017, Pages 75-82

  Biggs, Catherine M ^a,b   Keles, Sevgi ^c   Chatila, Talal A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c NECMETTIN ERBAKAN UNIVERSITY   (Turkey)

Author keywords

Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3

Indexed keywords

MYELOID DIFFERENTIATION FACTOR 88; STAT3 PROTEIN; TOLL LIKE RECEPTOR; DOCK8 PROTEIN, HUMAN; GUANINE NUCLEOTIDE EXCHANGE FACTOR;

CLINICAL FEATURE; DEDICATOR OF CYTOKINESIS 2 DEFICIENCY; DEDICATOR OF CYTOKINESIS 8 DEFICIENCY; DOCK2 GENE; DOCK8 GENE; GENE; GENE MUTATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNE DEFICIENCY; IMMUNOPATHOGENESIS; IMMUNOPROPHYLAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; ACTIN FILAMENT; ADAPTIVE IMMUNITY; AUTOIMMUNE DISEASE; CELL MOTION; CELL SURVIVAL; ECZEMA; EPSTEIN BARR VIRUS INFECTION; GENETICS; HYPERSENSITIVITY; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGY; INFECTION; INFLAMMATION; INNATE IMMUNITY; METABOLISM; NEOPLASM; NUCLEOCYTOPLASMIC TRANSPORT; PAPILLOMAVIRUS INFECTION; RECURRENT DISEASE; RESPIRATORY TRACT DISEASE; VIRAL SKIN DISEASE; VIROLOGY;

ACTIN CYTOSKELETON; ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTIVE IMMUNITY; AUTOIMMUNE DISEASES; CELL MOVEMENT; CELL SURVIVAL; ECZEMA; EPSTEIN-BARR VIRUS INFECTIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; HYPERSENSITIVITY; IMMUNITY, INNATE; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFECTION; INFLAMMATION; NEOPLASMS; PAPILLOMAVIRUS INFECTIONS; RECURRENCE; RESPIRATORY TRACT DISEASES; SKIN DISEASES, VIRAL; STAT3 TRANSCRIPTION FACTOR;

EID: 85021122139     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2017.06.003     Document Type: Review

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