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Volumn 5, Issue , 2014, Pages

DOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs

Author keywords

[No Author keywords available]

Indexed keywords

DOCK8 PROTEIN; INTERLEUKIN 22; INTERLEUKIN 23; POLYPEPTIDE ANTIBIOTIC AGENT; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SCAFFOLD PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; DOCK8 PROTEIN, MOUSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 17; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; RORC PROTEIN, MOUSE;

EID: 84907336842     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5603     Document Type: Article
Times cited : (36)

References (62)
  • 1
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • DOI 10.1126/science.1104816
    • Backhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A. & Gordon, J. I. Host-bacterial mutualism in the human intestine. Science 307, 1915-1920 (2005 (Pubitemid 40404694)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1915-1920
    • Backhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3    Peterson, D.A.4    Gordon, J.I.5
  • 2
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper, L. V. & Macpherson, A. J. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat. Rev. Immunol. 10, 159-169 (2010
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 3
    • 84859384082 scopus 로고    scopus 로고
    • Innate lymphoid cells: Emerging insights in development, lineage relationships, and function
    • Spits, H. & Cupedo, T. Innate lymphoid cells: Emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 30, 647-675 (2012
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 647-675
    • Spits, H.1    Cupedo, T.2
  • 4
    • 0033602163 scopus 로고    scopus 로고
    • Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
    • Yokota, Y. et al. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397, 702-706 (1999
    • (1999) Nature , vol.397 , pp. 702-706
    • Yokota, Y.1
  • 5
    • 78650310810 scopus 로고    scopus 로고
    • The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling
    • Spits, H. & Di Santo, J. P. The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling. Nat. Immunol. 12, 21-27 (2011
    • (2011) Nat. Immunol. , vol.12 , pp. 21-27
    • Spits, H.1    Di Santo, J.P.2
  • 7
    • 84867636023 scopus 로고    scopus 로고
    • Innate lymphoid cells: Balancing immunity, inflammation, and tissue repair in the intestine
    • Tait Wojno, E. D. & Artis, D. Innate lymphoid cells: Balancing immunity, inflammation, and tissue repair in the intestine. Cell Host Microbe 12, 445-457 (2012
    • (2012) Cell Host Microbe , vol.12 , pp. 445-457
    • Tait Wojno, E.D.1    Artis, D.2
  • 8
    • 18844455031 scopus 로고    scopus 로고
    • Inducible lymphoid tissues in the adult gut: Recapitulation of a fetal developmental pathway?
    • DOI 10.1038/nri1600
    • Eberl, G. Inducible lymphoid tissues in the adult gut: Recapitulation of a fetal developmental pathway? Nat. Rev. Immunol. 5, 413-420 (2005 (Pubitemid 40685990)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.5 , pp. 413-420
    • Eberl, G.1
  • 9
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
    • Cella, M. et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457, 722-725 (2009
    • (2009) Nature , vol.457 , pp. 722-725
    • Cella, M.1
  • 10
    • 83855160821 scopus 로고    scopus 로고
    • Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles
    • Kiss, E. A. et al. Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334, 1561-1565 (2011
    • (2011) Science , vol.334 , pp. 1561-1565
    • Kiss, E.A.1
  • 11
    • 79952986650 scopus 로고    scopus 로고
    • RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
    • Sawa, S. et al. RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat. Immunol. 12, 320-326 (2011
    • (2011) Nat. Immunol. , vol.12 , pp. 320-326
    • Sawa, S.1
  • 12
    • 78751706261 scopus 로고    scopus 로고
    • CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut
    • Sonnenberg, G. F., Monticelli, L. A., Elloso, M. M., Fouser, L. A. & Artis, D. CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut. Immunity 34, 122-134 (2011
    • (2011) Immunity , vol.34 , pp. 122-134
    • Sonnenberg, G.F.1    Monticelli, L.A.2    Elloso, M.M.3    Fouser, L.A.4    Artis, D.5
  • 13
    • 79960500206 scopus 로고    scopus 로고
    • Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge
    • Tumanov, A. V. et al. Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host Microbe 10, 44-53 (2011
    • (2011) Cell Host Microbe , vol.10 , pp. 44-53
    • Tumanov, A.V.1
  • 14
    • 57449090428 scopus 로고    scopus 로고
    • Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease
    • Zenewicz, L. A. et al. Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity 29, 947-957 (2008
    • (2008) Immunity , vol.29 , pp. 947-957
    • Zenewicz, L.A.1
  • 15
    • 67650474246 scopus 로고    scopus 로고
    • Stat3 links il-22 signaling in intestinal epithelial cells to mucosal wound healing
    • Pickert, G. et al. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 206, 1465-1472 (2009
    • (2009) J. Exp. Med. , vol.206 , pp. 1465-1472
    • Pickert, G.1
  • 17
    • 84883172356 scopus 로고    scopus 로고
    • Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
    • Satpathy, A. T. et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat. Immunol. 14, 937-948 (2013
    • (2013) Nat. Immunol. , vol.14 , pp. 937-948
    • Satpathy, A.T.1
  • 18
    • 0037115488 scopus 로고    scopus 로고
    • Identification of an evolutionary conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
    • DOI 10.1242/jcs.00219
    • Cote, J. F. & Vuori, K. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell. Sci. 115, 4901-4913 (2002 (Pubitemid 36054642)
    • (2002) Journal of Cell Science , vol.115 , Issue.24 , pp. 4901-4913
    • Cote, J.-F.1    Vuori, K.2
  • 19
    • 4143087241 scopus 로고    scopus 로고
    • Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology
    • DOI 10.1016/j.febslet.2004.06.095, PII S0014579304008944
    • Ruusala, A. & Aspenstrom, P. Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology. FEBS Lett. 572, 159-166 (2004 (Pubitemid 39092529)
    • (2004) FEBS Letters , vol.572 , Issue.1-3 , pp. 159-166
    • Ruusala, A.1    Aspenstrom, P.2
  • 20
    • 84861236002 scopus 로고    scopus 로고
    • Dock8 functions as an adaptor that links tlr-myd88 signaling to B cell activation
    • Jabara, H. H. et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat. Immunol. 13, 612-620 (2012
    • (2012) Nat. Immunol. , vol.13 , pp. 612-620
    • Jabara, H.H.1
  • 21
    • 70949098060 scopus 로고    scopus 로고
    • Combined immunodeficiency associated with DOCK8 mutations
    • Zhang, Q. et al. Combined immunodeficiency associated with DOCK8 mutations. New Engl. J. Med. 361, 2046-2055 (2009
    • (2009) New Engl. J. Med. , vol.361 , pp. 2046-2055
    • Zhang, Q.1
  • 22
    • 71149115670 scopus 로고    scopus 로고
    • Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome
    • Engelhardt, K. R. et al. Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome. J. Allergy Clin. Immunol. 124, 1289-1302 e1284 (2009
    • (2009) J. Allergy Clin. Immunol. , vol.124
    • Engelhardt, K.R.1
  • 23
    • 78449249501 scopus 로고    scopus 로고
    • Dedicator of cytokinesis 8 (DOCK8) deficiency
    • Su, H. C. Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr. Opin. Allergy Clin. Immunol. 10, 515-520 (2010
    • (2010) Curr. Opin. Allergy Clin. Immunol. , vol.10 , pp. 515-520
    • Su, H.C.1
  • 24
    • 70449718702 scopus 로고    scopus 로고
    • Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
    • Randall, K. L. et al. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production. Nat. Immunol. 10, 1283-1291 (2009
    • (2009) Nat. Immunol. , vol.10 , pp. 1283-1291
    • Randall, K.L.1
  • 25
    • 80055107954 scopus 로고    scopus 로고
    • DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice
    • Randall, K. L. et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J. Exp. Med. 208, 2305-2320 (2011
    • (2011) J. Exp. Med. , vol.208 , pp. 2305-2320
    • Randall, K.L.1
  • 26
    • 84861078339 scopus 로고    scopus 로고
    • Dock8 is a cdc42 activator critical for interstitial dendritic cell migration during immune responses
    • Harada, Y. et al. DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. Blood 119, 4451-4461 (2012
    • (2012) Blood , vol.119 , pp. 4451-4461
    • Harada, Y.1
  • 29
    • 0347364688 scopus 로고    scopus 로고
    • Critical Role of T Cell-Dependent Serum Antibody, but Not the Gut-Associated Lymphoid Tissue, for Surviving Acute Mucosal Infection with Citrobacter rodentium, an Attaching and Effacing Pathogen
    • Bry, L. & Brenner, M. B. Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen. J. Immunol. 172, 433-441 (2004 (Pubitemid 38020498)
    • (2004) Journal of Immunology , vol.172 , Issue.1 , pp. 433-441
    • Bry, L.1    Brenner, M.B.2
  • 30
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces development of the T(H)17 lineage
    • Mangan, P. R. et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441, 231-234 (2006
    • (2006) Nature , vol.441 , pp. 231-234
    • Mangan, P.R.1
  • 31
    • 84870876967 scopus 로고    scopus 로고
    • Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria
    • Basu, R. et al. Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria. Immunity 37, 1061-1075 (2012
    • (2012) Immunity , vol.37 , pp. 1061-1075
    • Basu, R.1
  • 32
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg, G. F., Fouser, L. A. & Artis, D. Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat. Immunol. 12, 383-390 (2011
    • (2011) Nat. Immunol. , vol.12 , pp. 383-390
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 33
    • 68249137286 scopus 로고    scopus 로고
    • Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
    • Colonna, M. Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity. Immunity 31, 15-23 (2009
    • (2009) Immunity , vol.31 , pp. 15-23
    • Colonna, M.1
  • 34
    • 84890892433 scopus 로고    scopus 로고
    • Il-23r innate lymphoid cells induce colitis via interleukin-22-dependent mechanism
    • Eken, A., Singh, A. K., Treuting, P. M. & Oukka, M. IL-23R innate lymphoid cells induce colitis via interleukin-22-dependent mechanism. Mucosal Immunol. 7, 143-154 (2013
    • (2013) Mucosal Immunol. , vol.7 , pp. 143-154
    • Eken, A.1    Singh, A.K.2    Treuting, P.M.3    Oukka, M.4
  • 35
    • 84887595223 scopus 로고    scopus 로고
    • Dock8 is critical for the survival and function of nkt cells
    • Crawford, G. et al. DOCK8 is critical for the survival and function of NKT cells. Blood 122, 2052-2061 (2013
    • (2013) Blood , vol.122 , pp. 2052-2061
    • Crawford, G.1
  • 36
    • 57449118239 scopus 로고    scopus 로고
    • Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
    • Satoh-Takayama, N. et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1
  • 37
    • 84856237141 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells
    • Qiu, J. et al. The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells. Immunity 36, 92-104 (2012
    • (2012) Immunity , vol.36 , pp. 92-104
    • Qiu, J.1
  • 38
    • 84855917402 scopus 로고    scopus 로고
    • Ahr drives the development of gut ilc22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch
    • Lee, J. S. et al. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat. Immunol. 13, 144-151 (2012
    • (2012) Nat. Immunol. , vol.13 , pp. 144-151
    • Lee, J.S.1
  • 39
    • 84892482473 scopus 로고    scopus 로고
    • Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection
    • Guo, X. et al. Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection. Immunity 40, 25-39 (2014
    • (2014) Immunity , vol.40 , pp. 25-39
    • Guo, X.1
  • 41
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells-A proposal for uniform nomenclature
    • Spits, H. et al. Innate lymphoid cells-a proposal for uniform nomenclature. Nat. Rev. Immunol. 13, 145-149 (2013
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 145-149
    • Spits, H.1
  • 42
    • 57849117363 scopus 로고    scopus 로고
    • Rorgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
    • Sanos, S. L. et al. RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat. Immunol. 10, 83-91 (2009
    • (2009) Nat. Immunol. , vol.10 , pp. 83-91
    • Sanos, S.L.1
  • 43
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464, 1371-1375 (2010
    • (2010) Nature , vol.464 , pp. 1371-1375
    • Buonocore, S.1
  • 44
    • 84867856710 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells
    • Powell, N. et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity 37, 674-684 (2012
    • (2012) Immunity , vol.37 , pp. 674-684
    • Powell, N.1
  • 45
    • 68649090645 scopus 로고    scopus 로고
    • Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells
    • Awasthi, A. et al. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J. Immunol. 182, 5904-5908 (2009
    • (2009) J. Immunol. , vol.182 , pp. 5904-5908
    • Awasthi, A.1
  • 46
    • 79960641541 scopus 로고    scopus 로고
    • Identity, regulation and in vivo function of gut nkp46+rorgammat+ and nkp46+rorgammat- lymphoid cells
    • Reynders, A. et al. Identity, regulation and in vivo function of gut NKp46+RORgammat+ and NKp46+RORgammat- lymphoid cells. EMBO J. 30, 2934-2947 (2011
    • (2011) EMBO J. , vol.30 , pp. 2934-2947
    • Reynders, A.1
  • 47
    • 84875454223 scopus 로고    scopus 로고
    • Dedicator of cytokinesis 8 interacts with talin and Wiskott- Aldrich syndrome protein to regulate NK cell cytotoxicity
    • Ham, H. et al. Dedicator of cytokinesis 8 interacts with talin and Wiskott- Aldrich syndrome protein to regulate NK cell cytotoxicity. J. Immunol. 190, 3661-3669 (2013
    • (2013) J. Immunol. , vol.190 , pp. 3661-3669
    • Ham, H.1
  • 48
    • 80052970974 scopus 로고    scopus 로고
    • Notch signaling is necessary for adult, but not fetal, development of rorgammat(+) innate lymphoid cells
    • Possot, C. et al. Notch signaling is necessary for adult, but not fetal, development of RORgammat(+) innate lymphoid cells. Nat. Immunol. 12, 949-958 (2011
    • (2011) Nat. Immunol. , vol.12 , pp. 949-958
    • Possot, C.1
  • 50
    • 34249014002 scopus 로고    scopus 로고
    • Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity
    • DOI 10.1084/jem.20061959
    • Boos, M. D., Yokota, Y., Eberl, G. & Kee, B. L. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J. Exp. Med. 204, 1119-1130 (2007 (Pubitemid 46798155)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.5 , pp. 1119-1130
    • Boos, M.D.1    Yokota, Y.2    Eberl, G.3    Kee, B.L.4
  • 51
    • 0346496018 scopus 로고    scopus 로고
    • An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells
    • DOI 10.1038/ni1022
    • Eberl, G. et al. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5, 64-73 (2004 (Pubitemid 38081470)
    • (2004) Nature Immunology , vol.5 , Issue.1 , pp. 64-73
    • Eberl, G.1    Marmon, S.2    Sunshine, M.-J.3    Rennert, P.D.4    Choi, Y.5    Littmann, D.R.6
  • 52
    • 77956963618 scopus 로고    scopus 로고
    • Shared dependence on the DNAbinding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages
    • Aliahmad, P., de la Torre, B. & Kaye, J. Shared dependence on the DNAbinding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages. Nat. Immunol. 11, 945-952 (2010
    • (2010) Nat. Immunol. , vol.11 , pp. 945-952
    • Aliahmad, P.1    De La Torre, B.2    Kaye, J.3
  • 53
    • 77149155687 scopus 로고    scopus 로고
    • Il-7 and il-15 independently program the differentiation of intestinal cd3-nkp46+ cell subsets from Id2-dependent precursors
    • Satoh-Takayama, N. et al. IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. J. Exp. Med. 207, 273-280 (2010
    • (2010) J. Exp. Med. , vol.207 , pp. 273-280
    • Satoh-Takayama, N.1
  • 54
    • 78649360369 scopus 로고    scopus 로고
    • Regulated expression of nuclear receptor RORgammat confers distinct functional fates to NK cell receptor-expressing RORgammat(+) innate lymphocytes
    • Vonarbourg, C. et al. Regulated expression of nuclear receptor RORgammat confers distinct functional fates to NK cell receptor-expressing RORgammat(+) innate lymphocytes. Immunity 33, 736-751 (2010
    • (2010) Immunity , vol.33 , pp. 736-751
    • Vonarbourg, C.1
  • 55
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang, J. H. et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5, 537-549 (1996
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1
  • 56
    • 84871902488 scopus 로고    scopus 로고
    • Distinct requirements for T-bet in gut innate lymphoid cells
    • Sciume, G. et al. Distinct requirements for T-bet in gut innate lymphoid cells. J. Exp. Med. 209, 2331-2338 (2012
    • (2012) J. Exp. Med. , vol.209 , pp. 2331-2338
    • Sciume, G.1
  • 57
    • 84875445419 scopus 로고    scopus 로고
    • The transcription factor t-bet is essential for the development of nkp46+ innate lymphocytes via the notch pathway
    • Rankin, L. C. et al. The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway. Nat. Immunol. 14, 389-395 (2013
    • (2013) Nat. Immunol. , vol.14 , pp. 389-395
    • Rankin, L.C.1
  • 58
    • 84873729246 scopus 로고    scopus 로고
    • A t-bet gradient controls the fate and function of ccr6- rorgammat+ innate lymphoid cells
    • Klose, C. S. et al. A T-bet gradient controls the fate and function of CCR6- RORgammat+ innate lymphoid cells. Nature 494, 261-265 (2013
    • (2013) Nature , vol.494 , pp. 261-265
    • Klose, C.S.1
  • 59
    • 84863985331 scopus 로고    scopus 로고
    • Additional diverse findings expand the clinical presentation of dock8 deficiency
    • Sanal, O. et al. Additional diverse findings expand the clinical presentation of DOCK8 deficiency. J. Clin. Immunol. 32, 698-708 (2012
    • (2012) J. Clin. Immunol. , vol.32 , pp. 698-708
    • Sanal, O.1
  • 60
    • 80054944901 scopus 로고    scopus 로고
    • Role of the commensal microbiota in normal and pathogenic host immune responses
    • Littman, D. R. & Pamer, E. G. Role of the commensal microbiota in normal and pathogenic host immune responses. Cell Host Microbe 10, 311-323 (2011
    • (2011) Cell Host Microbe , vol.10 , pp. 311-323
    • Littman, D.R.1    Pamer, E.G.2
  • 61
    • 84862777474 scopus 로고    scopus 로고
    • Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation
    • Hill, D. A. et al. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat. Med. 18, 538-546 (2012
    • (2012) Nat. Med. , vol.18 , pp. 538-546
    • Hill, D.A.1
  • 62
    • 77958153282 scopus 로고    scopus 로고
    • Il-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46
    • Eisenring, M., vom Berg, J., Kristiansen, G., Saller, E. & Becher, B. IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat. Immunol. 11, 1030-1038 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 1030-1038
    • Eisenring, M.1    Vom Berg, J.2    Kristiansen, G.3    Saller, E.4    Becher, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.