Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

Journal of Allergy and Clinical Immunology

Volumn 132, Issue 6, 2013, Pages

  Siegel, Andrea M ^a   Stone, Kelly D ^a   Cruse, Glenn ^a   Lawrence, Monica G ^a   Olivera, Ana ^b   Jung, Mi Yeon ^a   Barber, John S ^a   Freeman, Alexandra F ^a   Holland, Steven M ^a   O'Brien, Michelle ^a   Jones, Nina ^a   Wisch, Laura B ^a   Kong, Heidi H ^c   Desai, Avanti ^a   Farber, Orly ^a   Gilfillan, Alasdair M ^a   Rivera, Juan ^b   Milner, Joshua D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Autosomal dominant hyper IgE syndrome; degranulation; Job syndrome; mast cell; signal transducer and activator of transcription 3

Indexed keywords

IMMUNOGLOBULIN E; MORPHINE; MUTANT PROTEIN; STAT3 PROTEIN;

ALLERGIC DISEASE; ANAPHYLAXIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOPIC DERMATITIS; BASOPHIL; CONTROLLED STUDY; FEMALE; FOOD ALLERGY; GENE MUTATION; HUMAN; HYPER IGE SYNDROME; MAJOR CLINICAL STUDY; MALE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRICK TEST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

EID: 85027940079     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.08.045     Document Type: Article

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