Interleukin-1β (IL-1β) transcriptionally activates hepcidin by inducing CCAAT enhancer-binding protein δ (C/EBPδ) expression in hepatocytes

Journal of Biological Chemistry

Volumn 292, Issue 24, 2017, Pages 10275-10287

  Kanamori, Yohei ^a   Murakami, Masaru ^b   Sugiyama, Makoto ^c   Hashimoto, Osamu ^c   Matsui, Tohru ^a   Funaba, Masayuki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b AZABU UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; CELL CULTURE; CELLS; CYTOLOGY; LIVER; MACROPHAGES; MAMMALS; PATHOLOGY; PROTEINS;

BONE MORPHOGENETIC PROTEINS; ENHANCER BINDING PROTEINS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGE-LIKE CELLS; PROINFLAMMATORY CYTOKINES; SIGNAL TRANSDUCERS; TRANSCRIPTIONAL LEVELS;

TRANSCRIPTION;

ALBUMIN; BONE MORPHOGENETIC PROTEIN 2; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; CCAAT ENHANCER BINDING PROTEIN EPSILON; HEPCIDIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPID; PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; CEBPD PROTEIN, HUMAN; CONDITIONED MEDIUM; HAMP PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BMP2 GENE; CEBP DELTA GENE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HEP-G2 CELL LINE; HEPCIDIN GENE; HUMAN; HUMAN CELL; INFLAMMATION; KUPFFER CELL; LIVER CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; RAW 264.7 CELL LINE; REGULATORY SEQUENCE; SIGNAL TRANSDUCTION; SUPERNATANT; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; CONDITIONED MEDIUM; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; MACROPHAGE; METABOLISM; RNA INTERFERENCE; SPRAGUE DAWLEY RAT;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-DELTA; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HEP G2 CELLS; HEPATOCYTES; HEPCIDINS; HUMANS; INTERLEUKIN-1BETA; KUPFFER CELLS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; PROMOTER REGIONS, GENETIC; RATS, SPRAGUE-DAWLEY; RAW 264.7 CELLS; RECOMBINANT PROTEINS; RNA INTERFERENCE; UP-REGULATION;

EID: 85020934597     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.770974     Document Type: Article

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