Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing

Cell

Volumn 169, Issue 7, 2017, Pages 1342-1356.e16

  Zheng, Chunhong ^a   Zheng, Liangtao ^a   Yoo, Jae Kwang ^b   Guo, Huahu ^a,c,d   Zhang, Yuanyuan ^a   Guo, Xinyi ^a   Kang, Boxi ^a   Hu, Ruozhen ^b   Huang, Julie Y ^b   Zhang, Qiming ^a   Liu, Zhouzerui ^a   Dong, Minghui ^a   Hu, Xueda ^a   Ouyang, Wenjun ^b   Peng, Jirun ^a,c,d   Zhang, Zemin ^a  

^a PEKING UNIVERSITY   (China)

^b AMGEN INC   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

bioinformatics; biomarkers; cancer immunology; hepatocellular carcinoma; immunotherapy; RNA seq; single cell sequencing; T cell exhaustion; T cell receptor; tumor infiltrating lymphocytes

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LAYILIN GENE; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RNA SEQUENCE; SINGLE CELL ANALYSIS; T LYMPHOCYTE SUBPOPULATION; TUMOR ASSOCIATED LEUKOCYTE; UPREGULATION; IMMUNOLOGY; LIVER TUMOR; PATHOLOGY; SEQUENCE ANALYSIS; TUMOR MICROENVIRONMENT;

CARCINOMA, HEPATOCELLULAR; CD8-POSITIVE T-LYMPHOCYTES; HUMANS; LIVER NEOPLASMS; LYMPHOCYTES, TUMOR-INFILTRATING; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TUMOR MICROENVIRONMENT;

EID: 85020894317     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.05.035     Document Type: Article

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