메뉴 건너뛰기




Volumn 77, Issue 2, 2016, Pages 201-213

Transcriptome profiling of human FoxP3+ regulatory T cells

(10)  Bhairavabhotla, Ravikiran a,c   Kim, Yong C a,d   Glass, Deborah D a   Escobar, Thelma M a,e   Patel, Mira C b,f   Zahr, Rami a   Nguyen, Cuong K a,g   Kilaru, Gokhul K a,h   Muljo, Stefan A a   Shevach, Ethan M a  


Author keywords

Differentially expressed; FoxP3; Gene signature; LAYN; MiR 146a; MiR 146b; MiR 21; MiRNA; nCounter analysis; PNA; RNA sequencing; RTKN2; Suppressive cells

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IKZF2 PROTEIN; MICRORNA; MICRORNA 125A 5P; MICRORNA 146A; MICRORNA 146B 5P; MICRORNA 21; MICRORNA 28 3P; MICRORNA 31; MICRORNA 34A; MICRORNA 598; MICRORNA 660; MICRORNA LET 7G; PEPTIDES AND PROTEINS; POLYADENYLATED RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTOME; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; LAYN PROTEIN, HUMAN; LECTIN; RTKN2 PROTEIN, HUMAN; SIGNAL PEPTIDE;

EID: 84958104365     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2015.12.004     Document Type: Article
Times cited : (65)

References (47)
  • 1
    • 84875498856 scopus 로고    scopus 로고
    • Development and maintenance of regulatory T cells
    • Ohkura N., Kitagawa Y., Sakaguchi S. Development and maintenance of regulatory T cells. Immunity 2013, 38:414-423.
    • (2013) Immunity , vol.38 , pp. 414-423
    • Ohkura, N.1    Kitagawa, Y.2    Sakaguchi, S.3
  • 2
    • 33745211931 scopus 로고    scopus 로고
    • Defective regulatory and effector T cell functions in patients with FOXP3 mutations
    • Bacchetta R., Passerini L., Gambineri E., Dai M., Allan S.E., Perroni L., et al. Defective regulatory and effector T cell functions in patients with FOXP3 mutations. J. Clin. Invest. 2006, 116:1713-1722.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1713-1722
    • Bacchetta, R.1    Passerini, L.2    Gambineri, E.3    Dai, M.4    Allan, S.E.5    Perroni, L.6
  • 3
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett C.L., Christie J., Ramsdell F., Brunkow M.E., Ferguson P.J., Whitesell L., et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 2001, 27:20-21.
    • (2001) Nat. Genet. , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3    Brunkow, M.E.4    Ferguson, P.J.5    Whitesell, L.6
  • 4
    • 65649129352 scopus 로고    scopus 로고
    • Control of type 1 diabetes by CD4+Foxp3+ regulatory T cells: lessons from mouse models and implications for human disease
    • Sgouroudis E., Piccirillo C. Control of type 1 diabetes by CD4+Foxp3+ regulatory T cells: lessons from mouse models and implications for human disease. Diabetes Metab. Res. Rev. 2009, 25:208-218.
    • (2009) Diabetes Metab. Res. Rev. , vol.25 , pp. 208-218
    • Sgouroudis, E.1    Piccirillo, C.2
  • 5
    • 75749124604 scopus 로고    scopus 로고
    • Development of thymically derived natural regulatory T cells
    • Bettini M.L., Vignali D.A. Development of thymically derived natural regulatory T cells. Ann. N. Y. Acad. Sci. 2010, 1183:1-12.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1183 , pp. 1-12
    • Bettini, M.L.1    Vignali, D.A.2
  • 7
    • 35448930435 scopus 로고    scopus 로고
    • Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
    • Tran D.Q., Ramsey H., Shevach E.M. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 2007, 110:2983-2990.
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 10
    • 33748460087 scopus 로고    scopus 로고
    • Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis
    • Sugimoto N., Oida T., Hirota K., Nakamura K., Nomura T., Uchiyama T., et al. Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int. Immunol. 2006, 18:1197-1209.
    • (2006) Int. Immunol. , vol.18 , pp. 1197-1209
    • Sugimoto, N.1    Oida, T.2    Hirota, K.3    Nakamura, K.4    Nomura, T.5    Uchiyama, T.6
  • 11
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus M.T., Sharp P.A. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 2002, 3:737-747.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 12
    • 51049089025 scopus 로고    scopus 로고
    • The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
    • Chong M.M., Rasmussen J.P., Rudensky A.Y., Littman D.R. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J. Exp. Med. 2008, 205:2005-2017.
    • (2008) J. Exp. Med. , vol.205 , pp. 2005-2017
    • Chong, M.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3    Littman, D.R.4
  • 13
    • 51049110261 scopus 로고    scopus 로고
    • Dicer-dependent microRNA pathway safeguards regulatory T cell function
    • Liston A., Lu L.F., O'Carroll D., Tarakhovsky A., Rudensky A.Y. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J. Exp. Med. 2008, 2008(205):1993-2004.
    • (2008) J. Exp. Med. , vol.2008 , Issue.205 , pp. 1993-2004
    • Liston, A.1    Lu, L.F.2    O'Carroll, D.3    Tarakhovsky, A.4    Rudensky, A.Y.5
  • 14
    • 77956632634 scopus 로고    scopus 로고
    • Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
    • Lu L.F., Boldin M.P., Chaudhry A., Lin L.L., Taganov K.D., Hanada T., et al. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 2010, 142:914-929.
    • (2010) Cell , vol.142 , pp. 914-929
    • Lu, L.F.1    Boldin, M.P.2    Chaudhry, A.3    Lin, L.L.4    Taganov, K.D.5    Hanada, T.6
  • 15
    • 58149268107 scopus 로고    scopus 로고
    • Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein
    • Lu L.F., Thai T.H., Calado D.P., Chaudhry A., Kubo M., Tanaka K., et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity 2009, 30:80-91.
    • (2009) Immunity , vol.30 , pp. 80-91
    • Lu, L.F.1    Thai, T.H.2    Calado, D.P.3    Chaudhry, A.4    Kubo, M.5    Tanaka, K.6
  • 16
    • 84878579282 scopus 로고    scopus 로고
    • DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability
    • Jeker L.T., Zhou X., Blelloch R., Bluestone J.A. DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS One 2013, 8:e66282.
    • (2013) PLoS One , vol.8 , pp. e66282
    • Jeker, L.T.1    Zhou, X.2    Blelloch, R.3    Bluestone, J.A.4
  • 18
    • 84866533054 scopus 로고    scopus 로고
    • A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
    • Fu W., Ergun A., Lu T., Hill J.A., Haxhinasto S., Fassett M.S., et al. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat. Immunol. 2012, 13:972-980.
    • (2012) Nat. Immunol. , vol.13 , pp. 972-980
    • Fu, W.1    Ergun, A.2    Lu, T.3    Hill, J.A.4    Haxhinasto, S.5    Fassett, M.S.6
  • 19
    • 80054079921 scopus 로고    scopus 로고
    • Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human
    • Birzele F., Fauti T., Stahl H., Lenter M.C., Simon E., Knebel D., et al. Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human. Nucleic Acids Res. 2011, 39:7946-7960.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7946-7960
    • Birzele, F.1    Fauti, T.2    Stahl, H.3    Lenter, M.C.4    Simon, E.5    Knebel, D.6
  • 20
    • 77955486658 scopus 로고    scopus 로고
    • Genome-Wide Identification of Human FOXP3 Target Genes in Natural Regulatory T Cells
    • Sadlon T.J., Wilkinson B.G., Pederson S., Brown C.Y., Bresatz S., Gargett T., et al. Genome-Wide Identification of Human FOXP3 Target Genes in Natural Regulatory T Cells. J. Immunol. 2010, 185:1071-1081.
    • (2010) J. Immunol. , vol.185 , pp. 1071-1081
    • Sadlon, T.J.1    Wilkinson, B.G.2    Pederson, S.3    Brown, C.Y.4    Bresatz, S.5    Gargett, T.6
  • 21
    • 84863360489 scopus 로고    scopus 로고
    • Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion
    • Kim Y.C., Bhairavabhotla R., Yoon J., Golding A., Thornton A.M., Tran D.Q., et al. Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion. Blood 2012, 119:2810-2818.
    • (2012) Blood , vol.119 , pp. 2810-2818
    • Kim, Y.C.1    Bhairavabhotla, R.2    Yoon, J.3    Golding, A.4    Thornton, A.M.5    Tran, D.Q.6
  • 22
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton A.M., Korty P.E., Tran D.Q., Wohlfert E.A., Murray P.E., Belkaid Y., et al. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 2010, 184:3433-3441.
    • (2010) J. Immunol. , vol.184 , pp. 3433-3441
    • Thornton, A.M.1    Korty, P.E.2    Tran, D.Q.3    Wohlfert, E.A.4    Murray, P.E.5    Belkaid, Y.6
  • 23
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B., Trapnell C., Pop M., Salzberg S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009, 2009(10):R25.
    • (2009) Genome Biol. , vol.2009 , Issue.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 25
    • 75249095274 scopus 로고    scopus 로고
    • DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
    • Wang L., Feng Z., Wang X., Wang X., Zhang X. DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 2010, 26:136-138.
    • (2010) Bioinformatics , vol.26 , pp. 136-138
    • Wang, L.1    Feng, Z.2    Wang, X.3    Wang, X.4    Zhang, X.5
  • 26
    • 84865554193 scopus 로고    scopus 로고
    • Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer
    • Alder H., Taccioli C., Chen H., Jiang Y., Smalley K.J., Fadda P., et al. Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. Carcinogenesis 2012, 33:1736-1744.
    • (2012) Carcinogenesis , vol.33 , pp. 1736-1744
    • Alder, H.1    Taccioli, C.2    Chen, H.3    Jiang, Y.4    Smalley, K.J.5    Fadda, P.6
  • 28
    • 64849088870 scopus 로고    scopus 로고
    • Analysis of adhesion molecules, target cells, and role of IL-in human FOXP3+ regulatory T cell suppressor function
    • Tran D.Q., Glass D.D., Uzel G., Darnell D.A., Spalding C., Holland S.M., et al. Analysis of adhesion molecules, target cells, and role of IL-in human FOXP3+ regulatory T cell suppressor function. J. Immunol. 2009, 182:2929-2938.
    • (2009) J. Immunol. , vol.182 , pp. 2929-2938
    • Tran, D.Q.1    Glass, D.D.2    Uzel, G.3    Darnell, D.A.4    Spalding, C.5    Holland, S.M.6
  • 29
    • 65549168545 scopus 로고    scopus 로고
    • Selective expression of latency-associated peptide (LAP) and IL-receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures
    • Tran D.Q., Andersson J., Hardwick D., Bebris L., Illei G.G., Shevach E.M. Selective expression of latency-associated peptide (LAP) and IL-receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures. Blood 2009, 113:5125-5133.
    • (2009) Blood , vol.113 , pp. 5125-5133
    • Tran, D.Q.1    Andersson, J.2    Hardwick, D.3    Bebris, L.4    Illei, G.G.5    Shevach, E.M.6
  • 30
    • 62749201002 scopus 로고    scopus 로고
    • Expansion of human regulatory T-cells from patients with type 1 diabetes
    • Putnam A.L., Brusko T.M., Lee M.R., Liu W., Szot G.L., Ghosh T., et al. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 2009, 58:652-662.
    • (2009) Diabetes , vol.58 , pp. 652-662
    • Putnam, A.L.1    Brusko, T.M.2    Lee, M.R.3    Liu, W.4    Szot, G.L.5    Ghosh, T.6
  • 31
    • 84887194102 scopus 로고    scopus 로고
    • Regulatory T-cell therapy in transplantation: moving to the clinic
    • Tang Q., Bluestone J.A. Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb. Perspect. Med. 2013, 3:a015552.
    • (2013) Cold Spring Harb. Perspect. Med. , vol.3 , pp. a015552
    • Tang, Q.1    Bluestone, J.A.2
  • 32
    • 78049330840 scopus 로고    scopus 로고
    • PNA-based antisense oligonucleotides for micrornas inhibition in the absence of a transfection reagent
    • Oh S.Y., Ju Y., Kim S., Park H. PNA-based antisense oligonucleotides for micrornas inhibition in the absence of a transfection reagent. Oligonucleotides 2010, 20:225-230.
    • (2010) Oligonucleotides , vol.20 , pp. 225-230
    • Oh, S.Y.1    Ju, Y.2    Kim, S.3    Park, H.4
  • 33
    • 84895880335 scopus 로고    scopus 로고
    • Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs
    • Smigielska-Czepiel K., van den Berg A., Jellema P., van der Lei R.J., Bijzet J., Kluiver J., et al. Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs. Genes Immun. 2014, 15:115-125.
    • (2014) Genes Immun. , vol.15 , pp. 115-125
    • Smigielska-Czepiel, K.1    van den Berg, A.2    Jellema, P.3    van der Lei, R.J.4    Bijzet, J.5    Kluiver, J.6
  • 34
    • 69449085219 scopus 로고    scopus 로고
    • GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells
    • Tran D.Q., Andersson J., Wang R., Ramsey H., Unutmaz D., Shevach E.M. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:13445-13450.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 13445-13450
    • Tran, D.Q.1    Andersson, J.2    Wang, R.3    Ramsey, H.4    Unutmaz, D.5    Shevach, E.M.6
  • 37
    • 84866893076 scopus 로고    scopus 로고
    • Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese
    • Myouzen K., Kochi Y., Okada Y., Terao C., Suzuki A., Ikari K., et al. Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese. PLoS Genet. 2012, 8:e1002949.
    • (2012) PLoS Genet. , vol.8 , pp. e1002949
    • Myouzen, K.1    Kochi, Y.2    Okada, Y.3    Terao, C.4    Suzuki, A.5    Ikari, K.6
  • 38
    • 0035167035 scopus 로고    scopus 로고
    • Layilin, a novel integral membrane protein, is a hyaluronan receptor
    • Bono P., Rubin K., Higgins J.M., Hynes R.O. Layilin, a novel integral membrane protein, is a hyaluronan receptor. Mol. Biol. Cell 2001, 12:891-900.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 891-900
    • Bono, P.1    Rubin, K.2    Higgins, J.M.3    Hynes, R.O.4
  • 39
    • 0032547737 scopus 로고    scopus 로고
    • Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles
    • Borowsky M.L., Hynes R.O. Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles. J. Cell Biol. 1998, 143:429-442.
    • (1998) J. Cell Biol. , vol.143 , pp. 429-442
    • Borowsky, M.L.1    Hynes, R.O.2
  • 40
    • 84877737255 scopus 로고    scopus 로고
    • Layilin, a talin-binding hyaluronan receptor, is expressed in human articular chondrocytes and synoviocytes and is down-regulated by interleukin-1beta
    • Murata M., Yudoh K., Shimizu H., Beppu M., Nakamura H., Kato T., et al. Layilin, a talin-binding hyaluronan receptor, is expressed in human articular chondrocytes and synoviocytes and is down-regulated by interleukin-1beta. Mod. Rheumatol. 2013, 23:478-488.
    • (2013) Mod. Rheumatol. , vol.23 , pp. 478-488
    • Murata, M.1    Yudoh, K.2    Shimizu, H.3    Beppu, M.4    Nakamura, H.5    Kato, T.6
  • 41
    • 44849116626 scopus 로고    scopus 로고
    • Down-regulation of layilin, a novel hyaluronan receptor, via RNA interference, inhibits invasion and lymphatic metastasis of human lung A549 cells
    • Chen Z., Zhuo W., Wang Y., Ao X., An J. Down-regulation of layilin, a novel hyaluronan receptor, via RNA interference, inhibits invasion and lymphatic metastasis of human lung A549 cells. Biotechnol. Appl. Biochem. 2008, 50:89-96.
    • (2008) Biotechnol. Appl. Biochem. , vol.50 , pp. 89-96
    • Chen, Z.1    Zhuo, W.2    Wang, Y.3    Ao, X.4    An, J.5
  • 42
    • 69549120242 scopus 로고    scopus 로고
    • Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells
    • Pan F., Yu H., Dang E.V., Barbi J., Pan X., Grosso J.F., Jinasena D., et al. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science 2009, 325:1142-1146.
    • (2009) Science , vol.325 , pp. 1142-1146
    • Pan, F.1    Yu, H.2    Dang, E.V.3    Barbi, J.4    Pan, X.5    Grosso, J.F.6    Jinasena, D.7
  • 44
    • 84858986644 scopus 로고    scopus 로고
    • MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function
    • Fayyad-Kazan H., Rouas R., Fayyad-Kazan M., Badran R., El Zein N., Lewalle P., et al. MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function. J. Biol. Chem. 2012, 287:9910-9922.
    • (2012) J. Biol. Chem. , vol.287 , pp. 9910-9922
    • Fayyad-Kazan, H.1    Rouas, R.2    Fayyad-Kazan, M.3    Badran, R.4    El Zein, N.5    Lewalle, P.6
  • 45
    • 71349083569 scopus 로고    scopus 로고
    • MicroRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients
    • Hezova R., Slaby O., Faltejskova P., Mikulkova Z., Buresova I., Raja K.R., et al. MicroRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients. Cell. Immunol. 2010, 260:70-74.
    • (2010) Cell. Immunol. , vol.260 , pp. 70-74
    • Hezova, R.1    Slaby, O.2    Faltejskova, P.3    Mikulkova, Z.4    Buresova, I.5    Raja, K.R.6
  • 46
    • 84934946580 scopus 로고    scopus 로고
    • Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis
    • Zhou Q., Haupt S., Kreuzer J.T., Hammitzsch A., Proft F., Neumann C., et al. Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis. Ann. Rheum. Dis. 2015, 74:1265-1274.
    • (2015) Ann. Rheum. Dis. , vol.74 , pp. 1265-1274
    • Zhou, Q.1    Haupt, S.2    Kreuzer, J.T.3    Hammitzsch, A.4    Proft, F.5    Neumann, C.6
  • 47
    • 67649528173 scopus 로고    scopus 로고
    • Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression
    • Rouas R., Fayyad-Kazan H., El Zein N., Lewalle P., Rothe F., Simion A., et al. Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression. Eur. J. Immunol. 2009, 39:1608-1618.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1608-1618
    • Rouas, R.1    Fayyad-Kazan, H.2    El Zein, N.3    Lewalle, P.4    Rothe, F.5    Simion, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.