Fat mass and obesity-associated protein attenuates lipid accumulation in macrophage foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice

Journal of Hypertension

Volumn 35, Issue 4, 2017, Pages 810-821

  Mo, Chunfen ^a,b   Yang, Ming ^a   Han, Xiaojuan ^a   Li, Junhong ^a   Gao, Guangping ^c   Tai, Haoran ^a   Huang, Ning ^a   Xiao, Hengyi ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Adeno associated virus serotype 9; Apolipoprotein E deficient mice; Atherosclerosis; Fat mass and obesity associated protein; Macrophages

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ACETYL COENZYME A CARBOXYLASE; ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE FTO; APOLIPOPROTEIN E; CD36 ANTIGEN; CHOLESTEROL; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INFLAMMASOME; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMALL INTERFERING RNA; ABC TRANSPORTER; LOW DENSITY LIPOPROTEIN;

ADENO ASSOCIATED VIRUS 9; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FOAM CELL; HYPERCHOLESTEROLEMIA; LIPID STORAGE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BLOOD; DEFICIENCY; GENETIC TRANSFECTION; GENETICS; METABOLISM; OBESITY; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC;

ACETYL-COA CARBOXYLASE; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIGENS, CD36; APOLIPOPROTEINS E; ATP BINDING CASSETTE TRANSPORTER 1; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 1; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; FOAM CELLS; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPROTEINS, LDL; MALE; MICE; OBESITY; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC; PPAR GAMMA; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; UP-REGULATION;

EID: 85020622658     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000001255     Document Type: Article

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