메뉴 건너뛰기




Volumn 120, Issue 9, 2011, Pages 403-413

Conditional expression of the FTO gene product in rat INS-1 cells reveals its rapid turnover and a role in the profile of glucose-induced insulin secretion

Author keywords

cell; Fat mass and obesity associated (FTO); Glucose induced insulin secretion; Signal transducer and activator of transcription 3 (STAT3); Ubiquitin proteasome

Indexed keywords

FTO GENE PRODUCT; GENE PRODUCT; GLUCOSE; HEMAGGLUTININ; PROTEASOME INHIBITOR; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 79951775774     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20100416     Document Type: Article
Times cited : (26)

References (32)
  • 1
    • 12444327152 scopus 로고    scopus 로고
    • Prevalence of obesity in Great Britain
    • Rennie, K. L. and Jebb, S. A. (2005) Prevalence of obesity in Great Britain. Obes. Rev. 6, 11-12
    • (2005) Obes. Rev. , vol.6 , pp. 11-12
    • Rennie, K.L.1    Jebb, S.A.2
  • 2
    • 46249128314 scopus 로고    scopus 로고
    • Childhood obesity: Genetic and environmental overlap with normal-range BMI
    • DOI 10.1038/oby.2008.240, PII OBY2008240
    • Haworth, C. M., Plomin, R., Carnell, S. and Wardle, J. (2008) Childhood obesity: genetic and environmental overlap with normal-range BMI. Obesity 16, 1585-1590 (Pubitemid 351915111)
    • (2008) Obesity , vol.16 , Issue.7 , pp. 1585-1590
    • Haworth, C.M.A.1    Plomin, R.2    Carnell, S.3    Wardle, J.4
  • 4
    • 14544272858 scopus 로고    scopus 로고
    • Monogenic obesity in humans
    • Farooqi, I. S. and O'Rahilly, S. (2005) Monogenic obesity in humans. Annu. Rev. Med. 56, 443-458
    • (2005) Annu. Rev. Med. , vol.56 , pp. 443-458
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 10
    • 0028025622 scopus 로고
    • Programmed cell death is affected in the novel mouse mutant Fused toes (Ft)
    • van der Hoeven, F., Schimmang, T., Volkmann, A., Mattei, M. G., Kyewski, B. and Ruther, U. (1994) Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development 120, 2601-2607 (Pubitemid 24268833)
    • (1994) Development , vol.120 , Issue.9 , pp. 2601-2607
    • Van, D.H.F.1    Schimmang, T.2    Volkmann, A.3    Mattei, M.-G.4    Kyewski, B.5    Ruther, U.6
  • 11
    • 0032886705 scopus 로고    scopus 로고
    • Cloning of Fatso (Fto), a novel gene deleted by the fused toes (Ft) mouse mutation
    • DOI 10.1007/s003359901144
    • Peters, T., Ausmeier, K. and Ruther, U. (1999) Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation. Mamm. Genome 10, 983-986 (Pubitemid 29470939)
    • (1999) Mammalian Genome , vol.10 , Issue.10 , pp. 983-986
    • Peters, T.1    Ausmeier, K.2    Ruther, U.3
  • 13
    • 54849381000 scopus 로고    scopus 로고
    • Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
    • Jia, G., Yang, C. G., Yang, S., Jian, X., Yi, C., Zhou, Z. and He, C. (2008) Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 582, 3313-3319
    • (2008) FEBS Lett. , vol.582 , pp. 3313-3319
    • Jia, G.1    Yang, C.G.2    Yang, S.3    Jian, X.4    Yi, C.5    Zhou, Z.6    He, C.7
  • 15
    • 44949202400 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase-BL, modulates pancreatic β-cell proliferation by interaction with the Wnt signalling pathway
    • Welters, H. J., Oknianska, A., Erdmann, K. S., Ryffel, G. U. and Morgan, N. G. (2008) The protein tyrosine phosphatase-BL, modulates pancreatic β-cell proliferation by interaction with the Wnt signalling pathway. J. Endocrinol. 197, 543-552
    • (2008) J. Endocrinol. , vol.197 , pp. 543-552
    • Welters, H.J.1    Oknianska, A.2    Erdmann, K.S.3    Ryffel, G.U.4    Morgan, N.G.5
  • 16
    • 16544379441 scopus 로고    scopus 로고
    • Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line
    • Thomas, H., Senkel, S., Erdmann, S., Arndt, T., Turan, G., Klein-Hitpass, L. and Ryffel, G. U. (2004) Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line. Nucleic Acids Res. 32, e150
    • (2004) Nucleic Acids Res. , vol.32
    • Thomas, H.1    Senkel, S.2    Erdmann, S.3    Arndt, T.4    Turan, G.5    Klein-Hitpass, L.6    Ryffel, G.U.7
  • 18
    • 84872249908 scopus 로고
    • Maintenance of human normal cells in continuous culture: Preliminary report; cultivation of mesoblastic tumors and normal cells and notes on methods of culture
    • Gey, G. O. and Gey, M. K. (1936) Maintenance of human normal cells in continuous culture: preliminary report; cultivation of mesoblastic tumors and normal cells and notes on methods of culture. Am. J. Cancer 27, 45-76
    • (1936) Am. J. Cancer , vol.27 , pp. 45-76
    • Gey, G.O.1    Gey, M.K.2
  • 19
    • 73349131422 scopus 로고    scopus 로고
    • The measurement of insulin secretion using pancreas perfusion in the rodent
    • Wargent, E. T. (2009) The measurement of insulin secretion using pancreas perfusion in the rodent. Methods Mol Biol. 560, 203-219
    • (2009) Methods Mol Biol. , vol.560 , pp. 203-219
    • Wargent, E.T.1
  • 20
    • 33746721402 scopus 로고    scopus 로고
    • Conditional expression of hepatocyte nuclear factor-1β, the maturity-onset diabetes of the young-5 gene product, influences the viability and functional competence of pancreatic β-cells
    • Welters, H. J., Senkel, S., Klein-Hitpass, L., Erdmann, S., Thomas, H., Harries, L.W., Pearson, E. R., Bingham, C., Hattersley, A. T., Ryffel, G. U. and Morgan, N. G. (2006) Conditional expression of hepatocyte nuclear factor-1β, the maturity-onset diabetes of the young-5 gene product, influences the viability and functional competence of pancreatic β-cells. J. Endocrinol. 190, 171-181
    • (2006) J. Endocrinol. , vol.190 , pp. 171-181
    • Welters, H.J.1    Senkel, S.2    Klein-Hitpass, L.3    Erdmann, S.4    Thomas, H.5    Harries, L.W.6    Pearson, E.R.7    Bingham, C.8    Hattersley, A.T.9    Ryffel, G.U.10    Morgan, N.G.11
  • 22
    • 77649303960 scopus 로고    scopus 로고
    • Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats
    • Tung, Y. C., Ayuso, E., Shan, X., Bosch, F., O'Rahilly, S., Coll, A. P. and Yeo, G. S. (2010) Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS ONE 5, e8771
    • (2010) PLoS ONE , vol.5
    • Tung, Y.C.1    Ayuso, E.2    Shan, X.3    Bosch, F.4    O'Rahilly, S.5    Coll, A.P.6    Yeo, G.S.7
  • 29
    • 10644260422 scopus 로고    scopus 로고
    • Control of gene expression by CpG island methylation in normal cells
    • Strathdee, G., Sim, A. and Brown, R. (2004) Control of gene expression by CpG island methylation in normal cells. Biochem. Soc. Trans. 32, 913-915
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 913-915
    • Strathdee, G.1    Sim, A.2    Brown, R.3
  • 30
    • 0036314864 scopus 로고    scopus 로고
    • Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?
    • Gerich, J. E. (2002) Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes? Diabetes 51 (Suppl. 1), S117-S121
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Gerich, J.E.1
  • 31
    • 33745192054 scopus 로고    scopus 로고
    • The nuclear ubiquitin-proteasome system
    • von Mikecz, A. (2006) The nuclear ubiquitin-proteasome system. J. Cell. Sci. 119, 1977-1984
    • (2006) J. Cell. Sci. , vol.119 , pp. 1977-1984
    • Von Mikecz, A.1
  • 32
    • 15944406765 scopus 로고    scopus 로고
    • SUMO: A history of modification
    • Hay, R. T. (2005) SUMO: a history of modification. Mol. Cell. 18, 1-12
    • (2005) Mol. Cell. , vol.18 , pp. 1-12
    • Hay, R.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.