Palmitate induces VSMC apoptosis via toll like receptor (TLR)4/ROS/p53 pathway

Atherosclerosis

Volumn 263, Issue , 2017, Pages 74-81

  Zhang, Yuanjun ^a,b   Xia, Guanghao ^a,c   Zhang, Yaqiong ^b   Liu, Juxiang ^a,c   Liu, Xiaowei ^a   Li, Weihua ^c   Lv, Yaya ^a,c   Wei, Suhong ^a,c   Liu, Jing ^a,c   Quan, Jinxing ^a,c  

^a GANSU PROVINCIAL HOSPITAL   (China)

^b GANSU UNIVERSITY OF CHINESE MEDICINE   (China)

^c Key Laboratory for Gastrointestinal Disease of Gansu Province   (China)

Author keywords

Apoptosis; Oxidative stress; Palmitate; Toll like receptor 4; Vascular smooth muscle cells

Indexed keywords

APOCYNIN; CASPASE 3; CASPASE 9; DICHLORODIHYDROFLUORESCEIN DIACETATE; MESSENGER RNA; PALMITIC ACID; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; ENZYME INHIBITOR; PALMITIC ACID DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TLR4 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

AORTIC SMOOTH MUSCLE CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CRISPR CAS SYSTEM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EDITING; GENE SILENCING; HUMAN; HUMAN CELL; LENTIVIRINAE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TUNEL ASSAY; VASCULAR SMOOTH MUSCLE CELL; ANTAGONISTS AND INHIBITORS; ATHEROSCLEROSIS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; METABOLISM; OXIDATIVE STRESS; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE;

APOPTOSIS; ATHEROSCLEROSIS; CASPASE 3; CASPASE 9; CELL SURVIVAL; ENZYME INHIBITORS; HUMANS; IN SITU NICK-END LABELING; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASES; OXIDATIVE STRESS; PALMITATES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85020398529     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2017.06.002     Document Type: Article

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