Emodin induces growth arrest and death of human vascular smooth muscle cells through reactive oxygen species and p53

Journal of Cardiovascular Pharmacology

Volumn 49, Issue 5, 2007, Pages 253-260

  Wang, Xiangfei ^a   Zou, Yunzeng ^a   Sun, Aijun ^a   Xu, Danling ^a   Niu, Yuhong ^a   Wang, Shijun ^a   Wang, Keqiang ^a   Ge, Junbo ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Apoptosis; DNA damage; Emodin; NADPH oxidase; p53; Reactive oxygen species; Senescence; Vascular smooth muscle cell

Indexed keywords

DIPHENYLIODONIUM SALT; EMODIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CULTURE; CELL DEATH; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHROMATIN CONDENSATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DNA SYNTHESIS; DOSE RESPONSE; DRUG DISTRIBUTION; GROWTH DISORDER; HUMAN; HUMAN CELL; LYSOSOME; PRIORITY JOURNAL; RESTENOSIS; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANALYSIS OF VARIANCE; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; APOPTOSIS; CELL AGING; CELL CYCLE; CELL DEATH; CELL MOVEMENT; CELL PROLIFERATION; CORONARY RESTENOSIS; CORONARY STENOSIS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EMODIN; ENZYME INHIBITORS; GENE EXPRESSION PROFILING; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; UMBILICAL ARTERIES;

EID: 34249823942     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318033dfb3     Document Type: Article

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