Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats

Journal of Molecular Medicine

Volumn 93, Issue 12, 2015, Pages 1341-1354

  Carrillo Sepulveda, Maria Alicia ^a,e   Spitler, Kathryn ^b   Pandey, Deepesh ^c   Berkowitz, Dan E ^c   Matsumoto, Takayuki ^d  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HOSHI UNIVERSITY   (Japan)

^e NEW YORK INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Diabetes; High glucose; NF B; ROS; TLR4; Vascular smooth muscle cell

Indexed keywords

CLI 095; CYCLOHEXENE DERIVATIVE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; REACTIVE OXYGEN METABOLITE; RESATORVID; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ETHYL 6-(N-(2-CHLORO-4-FLUOROPHENYL)SULFAMOYL)CYCLOHEX-1-ENE-1-CARBOXYLATE; GLUCOSE BLOOD LEVEL; PROTEIN BINDING; SULFONAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IN VITRO STUDY; INNATE IMMUNITY; INTRACELLULAR SPACE; MALE; MESENTERIC ARTERY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; UPREGULATION; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION; GENETICS; METABOLISM; PROTEIN TRANSPORT; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GLUCOSE; MALE; MUSCLE, SMOOTH, VASCULAR; MYELOID DIFFERENTIATION FACTOR 88; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SULFONAMIDES; TOLL-LIKE RECEPTOR 4;

EID: 84948571469     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-015-1318-7     Document Type: Article

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