Secreted and transmembrane αklotho isoforms have different spatio-temporal profiles in the brain during aging and Alzheimer's disease progression

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Massó, Anna ^a   Sánchez, Angela ^a   Gimenez Llort, Lydia ^a,b   Lizcano, Jose Miguel ^a,b   Cañete, Manuel ^a   Garciá, Belen ^a   Torres Lista, Virginia ^a,b   Puig, Meritxell ^a   Bosch, Assumpció ^a   Chillon, Miguel ^a,c  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT DE NEUROCIÈNCIES   (Spain)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

KLOTHO PROTEIN; SECRETED ALPHA KLOTHO PROTEIN; TRANSMEMBRANE ALPHA KLOTHO PROTEIN; UNCLASSIFIED DRUG; BETA GLUCURONIDASE; ISOPROTEIN;

ADULT; AGED; AGING; ALPHA KLOTHO GENE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CEREBELLUM; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE COURSE; EXERCISE; FEMALE; GENE; GENE EXPRESSION PROFILING; HEALTHY LIFESTYLE; HIPPOCAMPUS; HUMAN; HUMAN CELL; LIFESTYLE; MALE; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; VOLUNTARY MODERATE CONTINUOUS EXERCISE; YOUNG ADULT; ALTERNATIVE RNA SPLICING; ANIMAL; CELL LINE; CHEMISTRY; GENETICS; GENOTYPE; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

AGING; ALTERNATIVE SPLICING; ALZHEIMER DISEASE; ANIMALS; BRAIN; CELL LINE; FEMALE; GENOTYPE; GLUCURONIDASE; HUMANS; MALE; MICE; POLYMERASE CHAIN REACTION; PROTEIN ISOFORMS;

EID: 84959020183     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0143623     Document Type: Article

References (36)

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