Long-Term Dietary Alpha-Linolenic Acid Supplement Alleviates Cognitive Impairment Correlate with Activating Hippocampal CREB Signaling in Natural Aging Rats

Molecular Neurobiology

Volumn 53, Issue 7, 2016, Pages 4772-4786

  Gao, Hui ^a   Yan, Peipei ^a   Zhang, Shun ^a   Huang, Hao ^a   Huang, Fenghong ^b   Sun, Taoping ^a   Deng, Qianchun ^b   Huang, Qingde ^b   Chen, Sijing ^a   Ye, Keqiang ^c   Xu, Jiqu ^b   Liu, Liegang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; ALA; Cognition; CREB BDNF TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LARD; LINOLENIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATIONAL STUDY; DIET SUPPLEMENTATION; DISEASE EXACERBATION; ENZYME PHOSPHORYLATION; FEMALE; HIPPOCAMPUS; LONG TERM CARE; MEMORY DISORDER; MENTAL PERFORMANCE; MORRIS WATER MAZE TEST; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY; ANIMAL; DIET THERAPY; DIETARY SUPPLEMENT; DRUG EFFECTS; MAZE TEST; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME FACTOR;

AGING; ALPHA-LINOLENIC ACID; ANIMALS; COGNITIVE DYSFUNCTION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIETARY SUPPLEMENTS; FEMALE; HIPPOCAMPUS; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84940537834     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9393-x     Document Type: Article

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