-
2
-
-
84947279101
-
CCR 20th Anniversary Commentary: Gene-expression signature in breast cancer-where did it start and where are we now?
-
Gingras I, Desmedt C, Ignatiadis M, Sotiriou C. CCR 20th Anniversary Commentary: gene-expression signature in breast cancer-where did it start and where are we now? Clin Cancer Res 2015;21:4743-6.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4743-4746
-
-
Gingras, I.1
Desmedt, C.2
Ignatiadis, M.3
Sotiriou, C.4
-
3
-
-
84862526929
-
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
-
Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012;486:395-9.
-
(2012)
Nature
, vol.486
, pp. 395-399
-
-
Shah, S.P.1
Roth, A.2
Goya, R.3
Oloumi, A.4
Ha, G.5
Zhao, Y.6
-
4
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012;486:400-4.
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Loo, P.4
Greenman, C.5
Wedge, D.C.6
-
5
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 2012;486:405-9.
-
(2012)
Nature
, vol.486
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
Brown, K.K.4
Carter, S.L.5
Frederick, A.M.6
-
6
-
-
84943613527
-
Comprehensive molecular portraits of invasive lobular breast cancer
-
Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, et al. Comprehensive molecular portraits of invasive lobular breast cancer. Cell 2015;163:506-19.
-
(2015)
Cell
, vol.163
, pp. 506-519
-
-
Ciriello, G.1
Gatza, M.L.2
Beck, A.H.3
Wilkerson, M.D.4
Rhie, S.K.5
Pastore, A.6
-
7
-
-
84862584058
-
Whole-genome analysis informs breast cancer response to aromatase inhibition
-
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012;486:353-60.
-
(2012)
Nature
, vol.486
, pp. 353-360
-
-
Ellis, M.J.1
Ding, L.2
Shen, D.3
Luo, J.4
Suman, V.J.5
Wallis, J.W.6
-
8
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
The Cancer Genome Atlas Network
-
The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
9
-
-
84973594792
-
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
-
Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X, et al. Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature 2016;534:47-54.
-
(2016)
Nature
, vol.534
, pp. 47-54
-
-
Nik-Zainal, S.1
Davies, H.2
Staaf, J.3
Ramakrishna, M.4
Glodzik, D.5
Zou, X.6
-
10
-
-
84968619379
-
The somatic mutation profiles of 2, 433 breast cancers refines their genomic and transcriptomic landscapes
-
Pereira B, Chin SF, Rueda OM, Vollan HK, Provenzano E, Bardwell HA, et al. The somatic mutation profiles of 2, 433 breast cancers refines their genomic and transcriptomic landscapes. Nat Commun 2016;7:11479.
-
(2016)
Nat Commun
, vol.7
, pp. 11479
-
-
Pereira, B.1
Chin, S.F.2
Rueda, O.M.3
Vollan, H.K.4
Provenzano, E.5
Bardwell, H.A.6
-
11
-
-
84928969113
-
Genomic profiling of advanced-stage, metaplastic breast carcinoma by next-generation sequencing reveals frequent, targetable genomic abnormalities and potential new treatment options
-
Ross JS, Badve S, Wang K, Sheehan CE, Boguniewicz AB, Otto GA, et al. Genomic profiling of advanced-stage, metaplastic breast carcinoma by next-generation sequencing reveals frequent, targetable genomic abnormalities and potential new treatment options. Arch Pathol Lab Med 2015;139:642-9.
-
(2015)
Arch Pathol Lab Med
, vol.139
, pp. 642-649
-
-
Ross, J.S.1
Badve, S.2
Wang, K.3
Sheehan, C.E.4
Boguniewicz, A.B.5
Otto, G.A.6
-
12
-
-
84940462439
-
Immunohistochemical and molecular profiling of histologically defined apocrine carcinomas of the breast
-
Vranic S, Marchio C, Castellano I, Botta C, Scalzo MS, Bender RP, et al. Immunohistochemical and molecular profiling of histologically defined apocrine carcinomas of the breast. Hum Pathol 2015;46:1350-9.
-
(2015)
Hum Pathol
, vol.46
, pp. 1350-1359
-
-
Vranic, S.1
Marchio, C.2
Castellano, I.3
Botta, C.4
Scalzo, M.S.5
Bender, R.P.6
-
13
-
-
84953278990
-
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer
-
Michaut M, Chin SF, Majewski I, Severson TM, Bismeijer T, de Koning L, et al. Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer. Sci Rep 2016;6:18517.
-
(2016)
Sci Rep
, vol.6
, pp. 18517
-
-
Michaut, M.1
Chin, S.F.2
Majewski, I.3
Severson, T.M.4
Bismeijer, T.5
De Koning, L.6
-
14
-
-
84979860042
-
The genomic landscape of male breast cancers
-
Piscuoglio S, Ng CK, Murray MP, Guerini-Rocco E, Martelotto LG, Geyer FC, et al. The genomic landscape of male breast cancers. Clin Cancer Res 2016;22:4045-56.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 4045-4056
-
-
Piscuoglio, S.1
Ng, C.K.2
Murray, M.P.3
Guerini-Rocco, E.4
Martelotto, L.G.5
Geyer, F.C.6
-
15
-
-
84959488493
-
Genetic alterations of triple negative breast cancer by targeted nextgeneration sequencing and correlation with tumor morphology
-
Weisman PS, Ng CK, Brogi E, Eisenberg RE, Won HH, Piscuoglio S, et al. Genetic alterations of triple negative breast cancer by targeted nextgeneration sequencing and correlation with tumor morphology. Mod Pathol 2016;29:476-88.
-
(2016)
Mod Pathol
, vol.29
, pp. 476-488
-
-
Weisman, P.S.1
Ng, C.K.2
Brogi, E.3
Eisenberg, R.E.4
Won, H.H.5
Piscuoglio, S.6
-
16
-
-
85007282397
-
The genetic landscape of breast carcinomas with neuroendocrine differentiation
-
Marchio C, Geyer FC, Ng CK, Piscuoglio S, De Filippo MR, Cupo M, et al. The genetic landscape of breast carcinomas with neuroendocrine differentiation. J Pathol 2016;241:405-19.
-
(2016)
J Pathol
, vol.241
, pp. 405-419
-
-
Marchio, C.1
Geyer, F.C.2
Ng, C.K.3
Piscuoglio, S.4
De Filippo, M.R.5
Cupo, M.6
-
17
-
-
84974539687
-
Genomic characterization of primary invasive lobular breast cancer
-
Desmedt C, Zoppoli G, Gundem G, Pruneri G, Larsimont D, Fornili M, et al. Genomic characterization of primary invasive lobular breast cancer. J Clin Oncol 2016;34:1872-81.
-
(2016)
J Clin Oncol
, vol.34
, pp. 1872-1881
-
-
Desmedt, C.1
Zoppoli, G.2
Gundem, G.3
Pruneri, G.4
Larsimont, D.5
Fornili, M.6
-
18
-
-
84961160009
-
Whole exome sequencing of rare aggressive breast cancer histologies
-
Dieci MV, Smutna V, Scott V, Yin G, Xu R, Vielh P, et al. Whole exome sequencing of rare aggressive breast cancer histologies. Breast Cancer Res Treat 2016;156:21-32.
-
(2016)
Breast Cancer Res Treat
, vol.156
, pp. 21-32
-
-
Dieci, M.V.1
Smutna, V.2
Scott, V.3
Yin, G.4
Xu, R.5
Vielh, P.6
-
19
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 2013;499:214-8.
-
(2013)
Nature
, vol.499
, pp. 214-218
-
-
Lawrence, M.S.1
Stojanov, P.2
Polak, P.3
Kryukov, G.V.4
Cibulskis, K.5
Sivachenko, A.6
-
20
-
-
84887032986
-
IntOGen-mutations identifies cancer drivers across tumor types
-
Gonzalez-Perez A, Perez-Llamas C, Deu-Pons J, Tamborero D, Schroeder MP, Jene-Sanz A, et al. IntOGen-mutations identifies cancer drivers across tumor types. Nat Methods 2013;10:1081-2.
-
(2013)
Nat Methods
, vol.10
, pp. 1081-1082
-
-
Gonzalez-Perez, A.1
Perez-Llamas, C.2
Deu-Pons, J.3
Tamborero, D.4
Schroeder, M.P.5
Jene-Sanz, A.6
-
21
-
-
84873802661
-
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
-
Reimand J, Bader GD. Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers. Mol Syst Biol 2013;9:637.
-
(2013)
Mol Syst Biol
, vol.9
, pp. 637
-
-
Reimand, J.1
Bader, G.D.2
-
22
-
-
84864598664
-
MuSiC: Identifying mutational significance in cancer genomes
-
Dees ND, Zhang Q, Kandoth C, Wendl MC, Schierding W, Koboldt DC, et al. MuSiC: identifying mutational significance in cancer genomes. Genome Res 2012;22:1589-98.
-
(2012)
Genome Res
, vol.22
, pp. 1589-1598
-
-
Dees, N.D.1
Zhang, Q.2
Kandoth, C.3
Wendl, M.C.4
Schierding, W.5
Koboldt, D.C.6
-
23
-
-
84929991442
-
Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin
-
Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, et al. Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science 2015;348:880-6.
-
(2015)
Science
, vol.348
, pp. 880-886
-
-
Martincorena, I.1
Roshan, A.2
Gerstung, M.3
Ellis, P.4
Van Loo, P.5
McLaren, S.6
-
24
-
-
84959111658
-
Mutation 3D: Cancer gene prediction through atomic clustering of coding variants in the structural proteome
-
Meyer MJ, Lapcevic R, Romero AE, Yoon M, Das J, Beltran JF, et al. Mutation 3D: cancer gene prediction through atomic clustering of coding variants in the structural proteome. Hum Mutat 2016;37:447-56.
-
(2016)
Hum Mutat
, vol.37
, pp. 447-456
-
-
Meyer, M.J.1
Lapcevic, R.2
Romero, A.E.3
Yoon, M.4
Das, J.5
Beltran, J.F.6
-
25
-
-
84869447682
-
Efficient methods for identifying mutated driver pathways in cancer
-
Zhao J, Zhang S, Wu LY, Zhang XS. Efficient methods for identifying mutated driver pathways in cancer. Bioinformatics 2012;28:2940-7.
-
(2012)
Bioinformatics
, vol.28
, pp. 2940-2947
-
-
Zhao, J.1
Zhang, S.2
Wu, L.Y.3
Zhang, X.S.4
-
26
-
-
84856535081
-
Mutual exclusivity analysis identifies oncogenic network modules
-
Ciriello G, Cerami E, Sander C, Schultz N. Mutual exclusivity analysis identifies oncogenic network modules. Genome Res 2012;22:398-406.
-
(2012)
Genome Res
, vol.22
, pp. 398-406
-
-
Ciriello, G.1
Cerami, E.2
Sander, C.3
Schultz, N.4
-
28
-
-
84906839586
-
DawnRank: Discovering personalized driver genesin cancer
-
Hou JP, Ma J. DawnRank: discovering personalized driver genesin cancer. Genome Med 2014;6:56.
-
(2014)
Genome Med
, vol.6
, pp. 56
-
-
Hou, J.P.1
Ma, J.2
-
29
-
-
84892833777
-
Discovery and saturation analysis of cancer genes across 21 tumour types
-
Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, et al. Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 2014;505:495-501.
-
(2014)
Nature
, vol.505
, pp. 495-501
-
-
Lawrence, M.S.1
Stojanov, P.2
Mermel, C.H.3
Robinson, J.T.4
Garraway, L.A.5
Golub, T.R.6
-
30
-
-
85007551444
-
Mutational profile of metastatic breast cancers: A retrospective analysis
-
Lefebvre C, Bachelot T, Filleron T, Pedrero M, Campone M, Soria JC, et al. Mutational profile of metastatic breast cancers: a retrospective analysis. PLoS Med 2016;13:e1002201.
-
(2016)
PLoS Med
, vol.13
, pp. e1002201
-
-
Lefebvre, C.1
Bachelot, T.2
Filleron, T.3
Pedrero, M.4
Campone, M.5
Soria, J.C.6
-
31
-
-
84869507148
-
Mucinous breast carcinomas lack PIK3CA and AKT1 mutations
-
Kehr EL, Jorns JM, Ang D, Warrick A, Neff T, Degnin M, et al. Mucinous breast carcinomas lack PIK3CA and AKT1 mutations. Hum Pathol 2012;43:2207-12.
-
(2012)
Hum Pathol
, vol.43
, pp. 2207-2212
-
-
Kehr, E.L.1
Jorns, J.M.2
Ang, D.3
Warrick, A.4
Neff, T.5
Degnin, M.6
-
32
-
-
84940842655
-
Genomic landscape of adenoid cystic carcinoma of the breast
-
Martelotto LG, De Filippo MR, Ng CK, Natrajan R, Fuhrmann L, Cyrta J, et al. Genomic landscape of adenoid cystic carcinoma of the breast. J Pathol 2015;237:179-89.
-
(2015)
J Pathol
, vol.237
, pp. 179-189
-
-
Martelotto, L.G.1
De Filippo, M.R.2
Ng, C.K.3
Natrajan, R.4
Fuhrmann, L.5
Cyrta, J.6
-
33
-
-
85020299641
-
The landscape of somatic genetic alterations in metaplastic breast carcinomas
-
Feb. 2. Epub ahead of print
-
Ng CKY, Piscuoglio S, Geyer FC, Burke KA, Pareja F, Eberle CA, et al. The landscape of somatic genetic alterations in metaplastic breast carcinomas. Clin Cancer Res 2017 Feb. 2. [Epub ahead of print].
-
(2017)
Clin Cancer Res
-
-
Ng, C.K.Y.1
Piscuoglio, S.2
Geyer, F.C.3
Burke, K.A.4
Pareja, F.5
Eberle, C.A.6
-
34
-
-
84888391516
-
ESR1 ligand-binding domain mutationsinhormone-resistant breastcancer
-
Toy W, Shen Y, Won H, Green B, Sakr RA, Will M, et al. ESR1 ligand-binding domain mutationsinhormone-resistant breastcancer. Nat Genet 2013;45:1439-45.
-
(2013)
Nat Genet
, vol.45
, pp. 1439-1445
-
-
Toy, W.1
Shen, Y.2
Won, H.3
Green, B.4
Sakr, R.A.5
Will, M.6
-
35
-
-
84981725439
-
Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers
-
Miller CA, Gindin Y, Lu C, Griffith OL, Griffith M, Shen D, et al. Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers. Nat Commun 2016;7:12498.
-
(2016)
Nat Commun
, vol.7
, pp. 12498
-
-
Miller, C.A.1
Gindin, Y.2
Lu, C.3
Griffith, O.L.4
Griffith, M.5
Shen, D.6
-
36
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, et al. Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat Med 2015;21:751-9.
-
(2015)
Nat Med
, vol.21
, pp. 751-759
-
-
Yates, L.R.1
Gerstung, M.2
Knappskog, S.3
Desmedt, C.4
Gundem, G.5
Van Loo, P.6
-
37
-
-
84896689570
-
Molecular profiling ofthe residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets
-
Balko JM, Giltnane JM, Wang K, Schwarz LJ, Young CD, Cook RS, et al. Molecular profiling ofthe residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov 2014;4:232-45.
-
(2014)
Cancer Discov
, vol.4
, pp. 232-245
-
-
Balko, J.M.1
Giltnane, J.M.2
Wang, K.3
Schwarz, L.J.4
Young, C.D.5
Cook, R.S.6
-
38
-
-
84939165961
-
Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
-
Ng CK, Martelotto LG, Gauthier A, Wen HC, Piscuoglio S, Lim RS, et al. Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification. Genome Biol 2015;16:107.
-
(2015)
Genome Biol
, vol.16
, pp. 107
-
-
Ng, C.K.1
Martelotto, L.G.2
Gauthier, A.3
Wen, H.C.4
Piscuoglio, S.5
Lim, R.S.6
-
39
-
-
85011661149
-
Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples
-
Martelotto LG, Baslan T, Kendall J, Geyer FC, Burke KA, Spraggon L, et al. Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples. Nat Med 2017;23:376-85.
-
(2017)
Nat Med
, vol.23
, pp. 376-385
-
-
Martelotto, L.G.1
Baslan, T.2
Kendall, J.3
Geyer, F.C.4
Burke, K.A.5
Spraggon, L.6
-
40
-
-
84925500147
-
Convergent loss of PTEN leads to clinical resistance to a PI (3) Kalpha inhibitor
-
Juric D, Castel P, Griffith M, Griffith OL, Won HH, Ellis H, et al. Convergent loss of PTEN leads to clinical resistance to a PI (3) Kalpha inhibitor. Nature 2015;518:240-4.
-
(2015)
Nature
, vol.518
, pp. 240-244
-
-
Juric, D.1
Castel, P.2
Griffith, M.3
Griffith, O.L.4
Won, H.H.5
Ellis, H.6
-
41
-
-
84968903135
-
Coming of age: Ten years of next-generation sequencing technologies
-
Goodwin S, McPherson JD, McCombie WR. Coming of age: ten years of next-generation sequencing technologies. Nat Rev Genet 2016;17:333-51.
-
(2016)
Nat Rev Genet
, vol.17
, pp. 333-351
-
-
Goodwin, S.1
McPherson, J.D.2
McCombie, W.R.3
-
42
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin N, Kendall J, Troge J, Andrews P, Rodgers L, McIndoo J, et al. Tumour evolution inferred by single-cell sequencing. Nature 2011;472:90-4.
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
Kendall, J.2
Troge, J.3
Andrews, P.4
Rodgers, L.5
McIndoo, J.6
-
43
-
-
84980028158
-
Protein-structure-guided discovery offunctional mutations across 19 cancer types
-
Niu B, Scott AD, Sengupta S, Bailey MH, Batra P, Ning J, et al. Protein-structure-guided discovery offunctional mutations across 19 cancer types. Nat Genet 2016;48:827-37.
-
(2016)
Nat Genet
, vol.48
, pp. 827-837
-
-
Niu, B.1
Scott, A.D.2
Sengupta, S.3
Bailey, M.H.4
Batra, P.5
Ning, J.6
-
44
-
-
85006364768
-
A CRISPR/Cas9 functional screen identifies rare tumor suppressors
-
Katigbak A, Cencic R, Robert F, Senecha P, Scuoppo C, Pelletier J. A CRISPR/Cas9 functional screen identifies rare tumor suppressors. Sci Rep 2016;6:38968.
-
(2016)
Sci Rep
, vol.6
, pp. 38968
-
-
Katigbak, A.1
Cencic, R.2
Robert, F.3
Senecha, P.4
Scuoppo, C.5
Pelletier, J.6
-
45
-
-
84863338519
-
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
-
Janku F, Wheler JJ, Westin SN, Moulder SL, Naing A, Tsimberidou AM, et al. PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol 2012;30:777-82.
-
(2012)
J Clin Oncol
, vol.30
, pp. 777-782
-
-
Janku, F.1
Wheler, J.J.2
Westin, S.N.3
Moulder, S.L.4
Naing, A.5
Tsimberidou, A.M.6
-
46
-
-
73949090721
-
Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutional-based review
-
Dawood S, Broglio K, Buzdar AU, Hortobagyi GN, Giordano SH. Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review. J Clin Oncol 2010;28:92-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 92-98
-
-
Dawood, S.1
Broglio, K.2
Buzdar, A.U.3
Hortobagyi, G.N.4
Giordano, S.H.5
-
47
-
-
3042781552
-
Analysis of genomic targets reveals complex functions of MYC
-
Patel JH, Loboda AP, Showe MK, Showe LC, McMahon SB. Analysis of genomic targets reveals complex functions of MYC. Nat Rev Cancer 2004;4:562-8.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 562-568
-
-
Patel, J.H.1
Loboda, A.P.2
Showe, M.K.3
Showe, L.C.4
McMahon, S.B.5
-
49
-
-
84896098750
-
Mutant p53 in cancer: New functions and therapeutic opportunities
-
Muller PA, Vousden KH. Mutant p53 in cancer: new functions and therapeutic opportunities. Cancer Cell 2014;25:304-17.
-
(2014)
Cancer Cell
, vol.25
, pp. 304-317
-
-
Muller, P.A.1
Vousden, K.H.2
-
50
-
-
84872847361
-
The genomic landscape of breast cancer as a therapeutic roadmap
-
Ellis MJ, Perou CM. The genomic landscape of breast cancer as a therapeutic roadmap. Cancer Discov 2013;3:27-34.
-
(2013)
Cancer Discov
, vol.3
, pp. 27-34
-
-
Ellis, M.J.1
Perou, C.M.2
-
51
-
-
84964596701
-
Strategically targeting MYC in cancer
-
Posternak V, Cole MD. Strategically targeting MYC in cancer. F1000Res 2016;5.
-
(2016)
F1000Res
, pp. 5
-
-
Posternak, V.1
Cole, M.D.2
-
52
-
-
84992376478
-
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
-
Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, et al. PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression. Nat Med 2016;22:1321-9.
-
(2016)
Nat Med
, vol.22
, pp. 1321-1329
-
-
Horiuchi, D.1
Camarda, R.2
Zhou, A.Y.3
Yau, C.4
Momcilovic, O.5
Balakrishnan, S.6
-
53
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
Baselga J, Campone M, Piccart M, Burris HA III, Rugo HS, Sahmoud T, et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med 2012;366:520-9.
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
Burris, H.A.4
Rugo, H.S.5
Sahmoud, T.6
-
54
-
-
84937042338
-
Palbociclib in hormone-receptor-positive advanced breast cancer
-
Turner NC, Ro J, Andre F, Loi S, Verma S, Iwata H, et al. Palbociclib in hormone-receptor-positive advanced breast cancer. N Engl J Med 2015;373:209-19.
-
(2015)
N Engl J Med
, vol.373
, pp. 209-219
-
-
Turner, N.C.1
Ro, J.2
Andre, F.3
Loi, S.4
Verma, S.5
Iwata, H.6
-
55
-
-
84976416730
-
Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: Expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18
-
Finn RS, Crown JP, Ettl J, Schmidt M, Bondarenko IM, Lang I, et al. Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18. Breast Cancer Res 2016;18:67.
-
(2016)
Breast Cancer Res
, vol.18
, pp. 67
-
-
Finn, R.S.1
Crown, J.P.2
Ettl, J.3
Schmidt, M.4
Bondarenko, I.M.5
Lang, I.6
-
56
-
-
84958973417
-
Correlative analysis of genetic alterations and everolimus benefit in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: Results from BOLERO-2
-
Hortobagyi GN, Chen D, Piccart M, Rugo HS, Burris HA III, Pritchard KI, et al. Correlative analysis of genetic alterations and everolimus benefit in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: results from BOLERO-2. J Clin Oncol 2016;34:419-26.
-
(2016)
J Clin Oncol
, vol.34
, pp. 419-426
-
-
Hortobagyi, G.N.1
Chen, D.2
Piccart, M.3
Rugo, H.S.4
Burris, H.A.5
Pritchard, K.I.6
-
57
-
-
84948379606
-
Precision medicine for metastatic breast cancer-limitations and solutions
-
Arnedos M, Vicier C, Loi S, Lefebvre C, Michiels S, Bonnefoi H, et al. Precision medicine for metastatic breast cancer-limitations and solutions. Nat Rev Clin Oncol 2015;12:693-704.
-
(2015)
Nat Rev Clin Oncol
, vol.12
, pp. 693-704
-
-
Arnedos, M.1
Vicier, C.2
Loi, S.3
Lefebvre, C.4
Michiels, S.5
Bonnefoi, H.6
-
58
-
-
84939864059
-
Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations
-
Hyman DM, Puzanov I, Subbiah V, Faris JE, Chau I, Blay JY, et al. Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations. N Engl J Med 2015;373:726-36.
-
(2015)
N Engl J Med
, vol.373
, pp. 726-736
-
-
Hyman, D.M.1
Puzanov, I.2
Subbiah, V.3
Faris, J.E.4
Chau, I.5
Blay, J.Y.6
-
59
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, et al. Signatures of mutational processes in human cancer. Nature 2013;500:415-21.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
-
60
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD, Raine K, et al. Mutational processes molding the genomes of 21 breast cancers. Cell 2012;149:979-93.
-
(2012)
Cell
, vol.149
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
Van Loo, P.4
Greenman, C.D.5
Raine, K.6
-
61
-
-
85020311581
-
Mutational signatures in breast cancer: The problem at the DNA level
-
Nik-Zainal S, Morganella S. Mutational signatures in breast cancer: the problem at the DNA level. Clin Cancer Res 2017;23:2617-29.
-
(2017)
Clin Cancer Res
, vol.23
, pp. 2617-2629
-
-
Nik-Zainal, S.1
Morganella, S.2
-
62
-
-
84906303775
-
Mechanisms underlying mutational signatures in human cancers
-
Helleday T, Eshtad S, Nik-Zainal S. Mechanisms underlying mutational signatures in human cancers. Nat Rev Genet 2014;15:585-98.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 585-598
-
-
Helleday, T.1
Eshtad, S.2
Nik-Zainal, S.3
-
63
-
-
84980347772
-
Homologous recombination deficiency (HRD) score predicts response to platinum-containing neoadjuvant chemotherapy in patients with triple-negative breast cancer
-
Telli ML, Timms KM, Reid J, Hennessy B, Mills GB, Jensen KC, et al. Homologous recombination deficiency (HRD) score predicts response to platinum-containing neoadjuvant chemotherapy in patients with triple-negative breast cancer. Clin Cancer Res 2016;22:3764-73.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 3764-3773
-
-
Telli, M.L.1
Timms, K.M.2
Reid, J.3
Hennessy, B.4
Mills, G.B.5
Jensen, K.C.6
-
64
-
-
84901664854
-
Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers
-
Watkins JA, Irshad S, Grigoriadis A, Tutt AN. Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers. Breast Cancer Res 2014;16:211.
-
(2014)
Breast Cancer Res
, vol.16
, pp. 211
-
-
Watkins, J.A.1
Irshad, S.2
Grigoriadis, A.3
Tutt, A.N.4
-
65
-
-
84869079205
-
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
-
Abkevich V, Timms KM, Hennessy BT, Potter J, Carey MS, Meyer LA, et al. Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer. Br J Cancer 2012;107:1776-82.
-
(2012)
Br J Cancer
, vol.107
, pp. 1776-1782
-
-
Abkevich, V.1
Timms, K.M.2
Hennessy, B.T.3
Potter, J.4
Carey, M.S.5
Meyer, L.A.6
-
66
-
-
84866261844
-
Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents
-
Birkbak NJ, Wang ZC, Kim JY, Eklund AC, Li Q, Tian R, et al. Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents. Cancer Discov 2012;2:366-75.
-
(2012)
Cancer Discov
, vol.2
, pp. 366-375
-
-
Birkbak, N.J.1
Wang, Z.C.2
Kim, J.Y.3
Eklund, A.C.4
Li, Q.5
Tian, R.6
-
67
-
-
84868240146
-
Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation
-
Popova T, Manie E, Rieunier G, Caux-Moncoutier V, Tirapo C, Dubois T, et al. Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. Cancer Res 2012;72:5454-62.
-
(2012)
Cancer Res
, vol.72
, pp. 5454-5462
-
-
Popova, T.1
Manie, E.2
Rieunier, G.3
Caux-Moncoutier, V.4
Tirapo, C.5
Dubois, T.6
-
68
-
-
85010840152
-
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
-
Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, et al. A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat Genet 2017;49:341-8.
-
(2017)
Nat Genet
, vol.49
, pp. 341-348
-
-
Glodzik, D.1
Morganella, S.2
Davies, H.3
Simpson, P.T.4
Li, Y.5
Zou, X.6
-
69
-
-
84905842087
-
Breast-cancer risk in families with mutations in PALB2
-
Antoniou AC, Casadei S, Heikkinen T, Barrowdale D, Pylkas K, Roberts J, et al. Breast-cancer risk in families with mutations in PALB2. N Engl J Med 2014;371:497-506.
-
(2014)
N Engl J Med
, vol.371
, pp. 497-506
-
-
Antoniou, A.C.1
Casadei, S.2
Heikkinen, T.3
Barrowdale, D.4
Pylkas, K.5
Roberts, J.6
-
70
-
-
85015004520
-
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
-
Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, et al. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nat Med 2017;23:517-25.
-
(2017)
Nat Med
, vol.23
, pp. 517-525
-
-
Davies, H.1
Glodzik, D.2
Morganella, S.3
Yates, L.R.4
Staaf, J.5
Zou, X.6
-
71
-
-
84859628102
-
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers
-
Natrajan R, Mackay A, Lambros MB, Weigelt B, Wilkerson PM, Manie E, et al. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers. J Pathol 2012;227:29-41.
-
(2012)
J Pathol
, vol.227
, pp. 29-41
-
-
Natrajan, R.1
Mackay, A.2
Lambros, M.B.3
Weigelt, B.4
Wilkerson, P.M.5
Manie, E.6
-
72
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Network
-
The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-7.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
73
-
-
84903821816
-
TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
-
Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, et al. TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance. Clin Cancer Res 2014;20:3569-80.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 3569-3580
-
-
Silwal-Pandit, L.1
Vollan, H.K.2
Chin, S.F.3
Rueda, O.M.4
McKinney, S.5
Osako, T.6
-
74
-
-
84871357082
-
-
International Agency for Research on Cancer, World Health Organization, Lyon, France: International Agency for Research on Cancer
-
Lakhani SR, International Agency for Research on Cancer, World Health Organization. WHO classification of tumours of the breast. Lyon, France: International Agency for Research on Cancer; 2012.
-
(2012)
WHO Classification of Tumours of the breast.
-
-
Lakhani, S.R.1
-
75
-
-
84871995408
-
GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
-
Theodorou V, Stark R, Menon S, Carroll JS. GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility. Genome Res 2013;23:12-22.
-
(2013)
Genome Res
, vol.23
, pp. 12-22
-
-
Theodorou, V.1
Stark, R.2
Menon, S.3
Carroll, J.S.4
-
76
-
-
84955749929
-
Clinically advanced and metastatic pure mucinous carcinoma of the breast: A comprehensive genomic profiling study
-
Ross JS, Gay LM, Nozad S, Wang K, Ali SM, Boguniewicz A, etal. Clinically advanced and metastatic pure mucinous carcinoma of the breast: a comprehensive genomic profiling study. Breast Cancer Res Treat 2016;155:405-13.
-
(2016)
Breast Cancer Res Treat
, vol.155
, pp. 405-413
-
-
Ross, J.S.1
Gay, L.M.2
Nozad, S.3
Wang, K.4
Ali, S.M.5
Boguniewicz, A.6
-
77
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 2009;461:809-13.
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
Morin, R.D.2
Khattra, J.3
Prentice, L.4
Pugh, T.5
Burleigh, A.6
-
78
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010;464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
Larson, D.E.4
Chen, K.5
Wallis, J.W.6
-
79
-
-
84899837889
-
Concordance of genomic alterations between primary and recurrent breast cancer
-
Meric-Bernstam F, Frampton GM, Ferrer-Lozano J, Yelensky R, Perez-Fidalgo JA, Wang Y, et al. Concordance of genomic alterations between primary and recurrent breast cancer. Mol CancerTher 2014;13:1382-9.
-
(2014)
Mol CancerTher
, vol.13
, pp. 1382-1389
-
-
Meric-Bernstam, F.1
Frampton, G.M.2
Ferrer-Lozano, J.3
Yelensky, R.4
Perez-Fidalgo, J.A.5
Wang, Y.6
-
80
-
-
85007559199
-
Tumor evolution in two patients with basal-like breast cancer: A retrospective genomics study of multiple metastases
-
Hoadley KA, Siegel MB, Kanchi KL, Miller CA, Ding L, Zhao W, et al. Tumor evolution in two patients with basal-like breast cancer: a retrospective genomics study of multiple metastases. PLoS Med 2016;13:e1002174.
-
(2016)
PLoS Med
, vol.13
, pp. e1002174
-
-
Hoadley, K.A.1
Siegel, M.B.2
Kanchi, K.L.3
Miller, C.A.4
Ding, L.5
Zhao, W.6
-
81
-
-
85002640264
-
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
-
Demeulemeester J, Kumar P, Moller EK, Nord S, Wedge DC, Peterson A, et al. Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing. Genome Biol 2016;17:250.
-
(2016)
Genome Biol
, vol.17
, pp. 250
-
-
Demeulemeester, J.1
Kumar, P.2
Moller, E.K.3
Nord, S.4
Wedge, D.C.5
Peterson, A.6
-
82
-
-
84946215072
-
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
-
Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, et al. Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets. Cancer Discov 2015;5:1164-77.
-
(2015)
Cancer Discov
, vol.5
, pp. 1164-1177
-
-
Brastianos, P.K.1
Carter, S.L.2
Santagata, S.3
Cahill, D.P.4
Taylor-Weiner, A.5
Jones, R.T.6
-
83
-
-
85007518478
-
The subclonal architecture of metastatic breast cancer: Results from a prospective community-based rapid autopsy program "CASCADE"
-
Savas P, Teo ZL, Lefevre C, Flensburg C, Caramia F, Alsop K, et al. The subclonal architecture of metastatic breast cancer: results from a prospective community-based rapid autopsy program "CASCADE". PLoS Med 2016;13:e1002204.
-
(2016)
PLoS Med
, vol.13
, pp. e1002204
-
-
Savas, P.1
Teo, Z.L.2
Lefevre, C.3
Flensburg, C.4
Caramia, F.5
Alsop, K.6
-
84
-
-
85020255247
-
Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations
-
Brown D, Smeets D, Szekely B, Larsimont D, Szasz AM, Adnet PY, et al. Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations. Nat Commun 2017;8:14944.
-
(2017)
Nat Commun
, vol.8
, pp. 14944
-
-
Brown, D.1
Smeets, D.2
Szekely, B.3
Larsimont, D.4
Szasz, A.M.5
Adnet, P.Y.6
-
85
-
-
84953369032
-
Metastatic breast cancer patients: Attitudes toward tissue donation for rapid autopsy
-
Achkar T, Wilson J, Simon J, Rosenzweig M, Puhalla S. Metastatic breast cancer patients: attitudes toward tissue donation for rapid autopsy. Breast Cancer Res Treat 2016;155:159-64.
-
(2016)
Breast Cancer Res Treat
, vol.155
, pp. 159-164
-
-
Achkar, T.1
Wilson, J.2
Simon, J.3
Rosenzweig, M.4
Puhalla, S.5
-
86
-
-
85020262373
-
Abstract 1804 The driver landscape of breast cancer metastasis and relapse
-
Yates L. Abstract 1804 The driver landscape of breast cancer metastasis and relapse. Eur J Cancer 2015;51:S266.
-
(2015)
Eur J Cancer
, vol.51
, pp. S266
-
-
Yates, L.1
-
87
-
-
84884559238
-
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
-
Li S, Shen D, Shao J, Crowder R, Liu W, Prat A, et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep 2013;4:1116-30.
-
(2013)
Cell Rep
, vol.4
, pp. 1116-1130
-
-
Li, S.1
Shen, D.2
Shao, J.3
Crowder, R.4
Liu, W.5
Prat, A.6
-
88
-
-
84924418225
-
A multiplex allele-specific real-time PCR assay for screening of ESR1 mutations in metastatic breast cancer
-
Wang T, Liu JH, Zhang J, Wang L, Chen C, Dai PG. A multiplex allele-specific real-time PCR assay for screening of ESR1 mutations in metastatic breast cancer. Exp Mol Pathol 2015;98:152-7.
-
(2015)
Exp Mol Pathol
, vol.98
, pp. 152-157
-
-
Wang, T.1
Liu, J.H.2
Zhang, J.3
Wang, L.4
Chen, C.5
Dai, P.G.6
-
89
-
-
84888381937
-
Activating ESR1 mutations in hormone-resistant metastaticbreast cancer
-
Robinson DR, Wu YM, Vats P, Su F, Lonigro RJ, Cao X, et al. Activating ESR1 mutations in hormone-resistant metastaticbreast cancer. Nat Genet 2013;45:1446-51.
-
(2013)
Nat Genet
, vol.45
, pp. 1446-1451
-
-
Robinson, D.R.1
Wu, Y.M.2
Vats, P.3
Su, F.4
Lonigro, R.J.5
Cao, X.6
-
90
-
-
84946559772
-
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
-
Murtaza M, Dawson SJ, Pogrebniak K, Rueda OM, Provenzano E, Grant J, et al. Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer. Nat Commun 2015;6:8760.
-
(2015)
Nat Commun
, vol.6
, pp. 8760
-
-
Murtaza, M.1
Dawson, S.J.2
Pogrebniak, K.3
Rueda, O.M.4
Provenzano, E.5
Grant, J.6
-
91
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson SJ, Tsui DW, Murtaza M, Biggs H, Rueda OM, Chin SF, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 2013;368:1199-209.
-
(2013)
N Engl J Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
Biggs, H.4
Rueda, O.M.5
Chin, S.F.6
-
92
-
-
84906890825
-
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: A proof-of-principle
-
De Mattos-Arruda L, Weigelt B, Cortes J, Won HH, Ng CK, Nuciforo P, et al. Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle. Ann Oncol 2014;25:1729-35.
-
(2014)
Ann Oncol
, vol.25
, pp. 1729-1735
-
-
De Mattos-Arruda, L.1
Weigelt, B.2
Cortes, J.3
Won, H.H.4
Ng, C.K.5
Nuciforo, P.6
-
93
-
-
84940416459
-
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer
-
Garcia-Murillas I, Schiavon G, Weigelt B, Ng C, Hrebien S, Cutts RJ, et al. Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer. SciTransl Med 2015;7:302ra133.
-
(2015)
SciTransl Med
, vol.7
, pp. 302ra133
-
-
Garcia-Murillas, I.1
Schiavon, G.2
Weigelt, B.3
Ng, C.4
Hrebien, S.5
Cutts, R.J.6
-
94
-
-
84995436787
-
Impact of mutational profiles on response of primary oestrogen receptorpositive breast cancers to oestrogen deprivation
-
Gellert P, Segal CV, Gao Q, Lopez-Knowles E, Martin LA, Dodson A, et al. Impact of mutational profiles on response of primary oestrogen receptorpositive breast cancers to oestrogen deprivation. Nat Commun 2016;7:13294.
-
(2016)
Nat Commun
, vol.7
, pp. 13294
-
-
Gellert, P.1
Segal, C.V.2
Gao, Q.3
Lopez-Knowles, E.4
Martin, L.A.5
Dodson, A.6
-
95
-
-
84890252506
-
D538G mutation in estrogen receptor-alpha: A novel mechanism for acquired endocrine resistance in breast cancer
-
Merenbakh-Lamin K, Ben-Baruch N, Yeheskel A, Dvir A, Soussan-Gutman L, Jeselsohn R, et al. D538G mutation in estrogen receptor-alpha: a novel mechanism for acquired endocrine resistance in breast cancer. Cancer Res 2013;73:6856-64.
-
(2013)
Cancer Res
, vol.73
, pp. 6856-6864
-
-
Merenbakh-Lamin, K.1
Ben-Baruch, N.2
Yeheskel, A.3
Dvir, A.4
Soussan-Gutman, L.5
Jeselsohn, R.6
-
96
-
-
84947967799
-
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
-
Schiavon G, Hrebien S, Garcia-Murillas I, Cutts RJ, Pearson A, Tarazona N, et al. Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer. Sci Transl Med 2015;7:313ra182.
-
(2015)
Sci Transl Med
, vol.7
, pp. 313ra182
-
-
Schiavon, G.1
Hrebien, S.2
Garcia-Murillas, I.3
Cutts, R.J.4
Pearson, A.5
Tarazona, N.6
-
97
-
-
84979639070
-
Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant
-
Spoerke JM, Gendreau S, Walter K, Qiu J, Wilson TR, Savage H, et al. Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant. Nat Commun 2016;7:11579.
-
(2016)
Nat Commun
, vol.7
, pp. 11579
-
-
Spoerke, J.M.1
Gendreau, S.2
Walter, K.3
Qiu, J.4
Wilson, T.R.5
Savage, H.6
-
98
-
-
84983543658
-
Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer
-
Fribbens C, O'Leary B, Kilburn L, Hrebien S, Garcia-Murillas I, Beaney M, et al. Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer. J Clin Oncol 2016;34:2961-8.
-
(2016)
J Clin Oncol
, vol.34
, pp. 2961-2968
-
-
Fribbens, C.1
O'Leary, B.2
Kilburn, L.3
Hrebien, S.4
Garcia-Murillas, I.5
Beaney, M.6
-
99
-
-
85020241069
-
Whole exome and transcriptome sequencing of resistant ER+ metastatic breast cancer [abstract]
-
S1-01 2016 Dec. 6-10; San Antonio, TX. SABCS
-
Cohen O, Oh C, Waks A, Oliver N, Helvie K, Marini L, et al. Whole exome and transcriptome sequencing of resistant ER+ metastatic breast cancer [abstract]. In: Proceedings of the 39th Annual San Antonio Breast Cancer Symposium; 2016 Dec. 6-10; San Antonio, TX. SABCS; 2016. Abstract nr S1-01.
-
(2016)
Proceedings of the 39th Annual San Antonio Breast Cancer Symposium
-
-
Cohen, O.1
Oh, C.2
Waks, A.3
Oliver, N.4
Helvie, K.5
Marini, L.6
-
100
-
-
84970952279
-
Early adaptation and acquired resistance to CDK4/6 inhibition in estrogen receptor-positive breast cancer
-
Herrera-Abreu MT, Palafox M, Asghar U, Rivas MA, Cutts RJ, Garcia-Murillas I, et al. Early adaptation and acquired resistance to CDK4/6 inhibition in estrogen receptor-positive breast cancer. Cancer Res 2016;76:2301-13.
-
(2016)
Cancer Res
, vol.76
, pp. 2301-2313
-
-
Herrera-Abreu, M.T.1
Palafox, M.2
Asghar, U.3
Rivas, M.A.4
Cutts, R.J.5
Garcia-Murillas, I.6
-
101
-
-
84991573384
-
Acquired CDK6 amplification promotesbreastcancerresistancetoCDK4/6inhibitors and loss of ER signaling and dependence
-
Yang C, Li Z, Bhatt T, Dickler M, Giri D, Scaltriti M, et al. Acquired CDK6 amplification promotesbreastcancerresistancetoCDK4/6inhibitors and loss of ER signaling and dependence. Oncogene 2017;36:2255-64.
-
(2017)
Oncogene
, vol.36
, pp. 2255-2264
-
-
Yang, C.1
Li, Z.2
Bhatt, T.3
Dickler, M.4
Giri, D.5
Scaltriti, M.6
-
102
-
-
85013725717
-
Prevalence of ESR1 mutations in cell-free DNA and outcomes in meta-static breast cancer: A secondary analysis of the BOLERO-2 clinical trial
-
Chandarlapaty S, Chen D, He W, Sung P, Samoila A, You D, et al. Prevalence of ESR1 mutations in cell-free DNA and outcomes in meta-static breast cancer: a secondary analysis of the BOLERO-2 clinical trial. JAMA Oncol 2016;2:1310-5.
-
(2016)
JAMA Oncol
, vol.2
, pp. 1310-1315
-
-
Chandarlapaty, S.1
Chen, D.2
He, W.3
Sung, P.4
Samoila, A.5
You, D.6
-
103
-
-
84946719441
-
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
-
De Mattos-Arruda L, Mayor R, Ng CK, Weigelt B, Martinez-Ricarte F, Torrejon D, et al. Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma. Nat Commun 2015;6:8839.
-
(2015)
Nat Commun
, vol.6
, pp. 8839
-
-
De Mattos-Arruda, L.1
Mayor, R.2
Ng, C.K.3
Weigelt, B.4
Martinez-Ricarte, F.5
Torrejon, D.6
-
104
-
-
84883556505
-
Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer
-
Saini KS, Loi S, de Azambuja E, Metzger-Filho O, Saini ML, Ignatiadis M, et al. Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer. Cancer Treat Rev 2013;39:935-46.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 935-946
-
-
Saini, K.S.1
Loi, S.2
De Azambuja, E.3
Metzger-Filho, O.4
Saini, M.L.5
Ignatiadis, M.6
-
105
-
-
84928186818
-
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer
-
Bosch A, Li Z, Bergamaschi A, Ellis H, Toska E, Prat A, et al. PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer. Sci Transl Med 2015;7:283ra51.
-
(2015)
Sci Transl Med
, vol.7
, pp. 283ra51
-
-
Bosch, A.1
Li, Z.2
Bergamaschi, A.3
Ellis, H.4
Toska, E.5
Prat, A.6
-
106
-
-
84896730857
-
Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: A multicentre, prospective trial (SAFIR01/UNICANCER)
-
Andre F, Bachelot T, Commo F, Campone M, Arnedos M, Dieras V, et al. Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER). Lancet Oncol 2014;15:267-74.
-
(2014)
Lancet Oncol
, vol.15
, pp. 267-274
-
-
Andre, F.1
Bachelot, T.2
Commo, F.3
Campone, M.4
Arnedos, M.5
Dieras, V.6
-
107
-
-
84884376583
-
Molecular screening for cancer treatment optimization (MOSCATO 01): A prospective molecular triage trial-interim results
-
2512
-
Hollebecque A, Massard C, De Baere T, Auger N, Lacroix L, Koubi-Pick V, et al. Molecular screening for cancer treatment optimization (MOSCATO 01): a prospective molecular triage trial-interim results. J Clin Oncol 31, 2013 (suppl; abstr 2512).
-
(2013)
J Clin Oncol
, vol.31
-
-
Hollebecque, A.1
Massard, C.2
De Baere, T.3
Auger, N.4
Lacroix, L.5
Koubi-Pick, V.6
-
108
-
-
84954026435
-
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): A multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
-
Le Tourneau C, Delord JP, Gonçalves A, Gavoille C, Dubot C, Isambert N, et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet Oncol 2015;16:1324-34.
-
(2015)
Lancet Oncol
, vol.16
, pp. 1324-1334
-
-
Le Tourneau, C.1
Delord, J.P.2
Gonçalves, A.3
Gavoille, C.4
Dubot, C.5
Isambert, N.6
-
109
-
-
84937758852
-
Exome sequencing of contralateral breast cancer identifies metastatic disease
-
Klevebring D, Lindberg J, Rockberg J, Hilliges C, Hall P, Sandberg M, et al. Exome sequencing of contralateral breast cancer identifies metastatic disease. Breast Cancer Res Treat 2015;151:319-24.
-
(2015)
Breast Cancer Res Treat
, vol.151
, pp. 319-324
-
-
Klevebring, D.1
Lindberg, J.2
Rockberg, J.3
Hilliges, C.4
Hall, P.5
Sandberg, M.6
-
111
-
-
84991711126
-
A community-based model of rapid autopsy in end-stage cancer patients
-
Alsop K, Thorne H, Sandhu S, Hamilton A, Mintoff C, Christie E, et al. A community-based model of rapid autopsy in end-stage cancer patients. Nat Biotechnol 2016;34:1010-4.
-
(2016)
Nat Biotechnol
, vol.34
, pp. 1010-1014
-
-
Alsop, K.1
Thorne, H.2
Sandhu, S.3
Hamilton, A.4
Mintoff, C.5
Christie, E.6
|