메뉴 건너뛰기




Volumn 237, Issue 2, 2015, Pages 179-189

Genomic landscape of adenoid cystic carcinoma of the breast

Author keywords

adenoid cystic carcinoma; genomics; massively parallel sequencing; MYB NFIB; triple negative breast cancer

Indexed keywords

B RAF KINASE; BRCA1 PROTEIN; BRCA2 PROTEIN; FBXW7 PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 2; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN; PROTEIN MYB; PROTEIN P53; RNA; SF3B1 PROTEIN; SMARCA5 PROTEIN; TALIN; TALIN 2; UNCLASSIFIED DRUG; UVOMORULIN; MYB-NFIB FUSION PROTEIN, HUMAN; ONCOPROTEIN; TUMOR MARKER;

EID: 84940842655     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4573     Document Type: Article
Times cited : (133)

References (51)
  • 1
    • 77749295010 scopus 로고    scopus 로고
    • Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas)
    • Marchio C, Weigelt B, Reis-Filho JS,. Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas). J Clin Pathol 2010; 63: 220-228.
    • (2010) J Clin Pathol , vol.63 , pp. 220-228
    • Marchio, C.1    Weigelt, B.2    Reis-Filho, J.S.3
  • 2
    • 53149133527 scopus 로고    scopus 로고
    • Refinement of breast cancer classification by molecular characterization of histological special types
    • Weigelt B, Horlings HM, Kreike B, et al., Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol 2008; 216: 141-150.
    • (2008) J Pathol , vol.216 , pp. 141-150
    • Weigelt, B.1    Horlings, H.M.2    Kreike, B.3
  • 4
    • 75649149550 scopus 로고    scopus 로고
    • Histological and molecular types of breast cancer: Is there a unifying taxonomy?
    • Weigelt B, Reis-Filho JS,. Histological and molecular types of breast cancer: is there a unifying taxonomy? Nat Rev Clin Oncol 2009; 6: 718-730.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 718-730
    • Weigelt, B.1    Reis-Filho, J.S.2
  • 6
    • 71049185479 scopus 로고    scopus 로고
    • Breast carcinoma - Rare types: Review of the literature
    • Yerushalmi R, Hayes MM, Gelmon KA,. Breast carcinoma-rare types: review of the literature. Ann Oncol 2009; 20: 1763-1770.
    • (2009) Ann Oncol , vol.20 , pp. 1763-1770
    • Yerushalmi, R.1    Hayes, M.M.2    Gelmon, K.A.3
  • 7
    • 79955887119 scopus 로고    scopus 로고
    • Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: A review
    • Papaspyrou G, Hoch S, Rinaldo A, et al., Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: a review. Head Neck 2011; 33: 905-911.
    • (2011) Head Neck , vol.33 , pp. 905-911
    • Papaspyrou, G.1    Hoch, S.2    Rinaldo, A.3
  • 8
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • Persson M, Andren Y, Mark J, et al., Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci USA 2009; 106: 18740-18744.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18740-18744
    • Persson, M.1    Andren, Y.2    Mark, J.3
  • 9
    • 80052418887 scopus 로고    scopus 로고
    • Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms
    • Brill LB II, Kanner WA, Fehr A, et al., Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms. Mod Pathol 2011; 24: 1169-1176.
    • (2011) Mod Pathol , vol.24 , pp. 1169-1176
    • Brill, I.I.L.B.1    Kanner, W.A.2    Fehr, A.3
  • 10
    • 78650865073 scopus 로고    scopus 로고
    • MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation
    • West RB, Kong C, Clarke N, et al., MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation. Am J Surg Pathol 2011; 35: 92-99.
    • (2011) Am J Surg Pathol , vol.35 , pp. 92-99
    • West, R.B.1    Kong, C.2    Clarke, N.3
  • 11
    • 77957557959 scopus 로고    scopus 로고
    • Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance
    • Mitani Y, Li J, Rao PH, et al., Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: incidence, variability, and clinicopathologic significance. Clin Cancer Res 2010; 16: 4722-4731.
    • (2010) Clin Cancer Res , vol.16 , pp. 4722-4731
    • Mitani, Y.1    Li, J.2    Rao, P.H.3
  • 12
    • 84879689007 scopus 로고    scopus 로고
    • The mutational landscape of adenoid cystic carcinoma
    • Ho AS, Kannan K, Roy DM, et al., The mutational landscape of adenoid cystic carcinoma. Nat Genet 2013; 45: 791-798.
    • (2013) Nat Genet , vol.45 , pp. 791-798
    • Ho, A.S.1    Kannan, K.2    Roy, D.M.3
  • 13
    • 84879627051 scopus 로고    scopus 로고
    • Whole exome sequencing of adenoid cystic carcinoma
    • Stephens PJ, Davies HR, Mitani Y, et al., Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest 2013; 123: 2965-2968.
    • (2013) J Clin Invest , vol.123 , pp. 2965-2968
    • Stephens, P.J.1    Davies, H.R.2    Mitani, Y.3
  • 14
    • 82755177882 scopus 로고    scopus 로고
    • Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers
    • Wetterskog D, Lopez-Garcia MA, Lambros MB, et al., Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers. J Pathol 2012; 226: 84-96.
    • (2012) J Pathol , vol.226 , pp. 84-96
    • Wetterskog, D.1    Lopez-Garcia, M.A.2    Lambros, M.B.3
  • 15
    • 84874214482 scopus 로고    scopus 로고
    • Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations
    • Wetterskog D, Wilkerson PM, Rodrigues DN, et al., Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations. Histopathology 2013; 62: 543-550.
    • (2013) Histopathology , vol.62 , pp. 543-550
    • Wetterskog, D.1    Wilkerson, P.M.2    Rodrigues, D.N.3
  • 16
    • 84908339061 scopus 로고    scopus 로고
    • MYB-NFIB gene fusion in adenoid cystic carcinoma of the breast with special focus paid to the solid variant with basaloid features
    • D'Alfonso TM, Mosquera JM, MacDonald TY, et al., MYB-NFIB gene fusion in adenoid cystic carcinoma of the breast with special focus paid to the solid variant with basaloid features. Hum Pathol 2014; 45: 2270-2280.
    • (2014) Hum Pathol , vol.45 , pp. 2270-2280
    • D'Alfonso, T.M.1    Mosquera, J.M.2    MacDonald, T.Y.3
  • 17
    • 84861684265 scopus 로고    scopus 로고
    • Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma
    • Persson M, Andren Y, Moskaluk CA, et al., Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma. Genes Chromosomes Cancer 2012; 51: 805-817.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 805-817
    • Persson, M.1    Andren, Y.2    Moskaluk, C.A.3
  • 18
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • Shah SP, Roth A, Goya R, et al., The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012; 486: 395-399.
    • (2012) Nature , vol.486 , pp. 395-399
    • Shah, S.P.1    Roth, A.2    Goya, R.3
  • 19
    • 84877028141 scopus 로고    scopus 로고
    • The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours.
    • The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490: 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 20
    • 84890428094 scopus 로고    scopus 로고
    • Genomic profiling of histological special types of breast cancer
    • Horlings HM, Weigelt B, Anderson EM, et al., Genomic profiling of histological special types of breast cancer. Breast Cancer Res Treat 2013; 142: 257-269.
    • (2013) Breast Cancer Res Treat , vol.142 , pp. 257-269
    • Horlings, H.M.1    Weigelt, B.2    Anderson, E.M.3
  • 21
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston CW, Ellis IO,. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 1991; 19: 403-410.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 22
    • 84911967623 scopus 로고    scopus 로고
    • Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast
    • Piscuoglio S, Ng CK, Martelotto LG, et al., Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast. Mol Oncol 2014; 8: 1588-1602.
    • (2014) Mol Oncol , vol.8 , pp. 1588-1602
    • Piscuoglio, S.1    Ng, C.K.2    Martelotto, L.G.3
  • 23
    • 77954526150 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
    • Hammond ME, Hayes DF, Dowsett M, et al., American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol 2010; 28: 2784-2795.
    • (2010) J Clin Oncol , vol.28 , pp. 2784-2795
    • Hammond, M.E.1    Hayes, D.F.2    Dowsett, M.3
  • 24
    • 84890254448 scopus 로고    scopus 로고
    • Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
    • Wolff AC, Hammond ME, Hicks DG, et al., Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. J Clin Oncol 2013; 31: 3997-4013.
    • (2013) J Clin Oncol , vol.31 , pp. 3997-4013
    • Wolff, A.C.1    Hammond, M.E.2    Hicks, D.G.3
  • 25
    • 84955197830 scopus 로고    scopus 로고
    • Resolving quandaries: Basaloid adenoid cystic carcinoma or breast cylindroma? the role of massively parallel sequencing
    • Epub ahead of print
    • Fusco N, Colombo PE, Martelotto LG, et al., Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing. Histopathology 2015; doi: 10.1111/his.12735. Epub ahead of print.
    • (2015) Histopathology
    • Fusco, N.1    Colombo, P.E.2    Martelotto, L.G.3
  • 26
    • 79958200205 scopus 로고    scopus 로고
    • The MYB-NFIB gene fusion - A novel genetic link between adenoid cystic carcinoma and dermal cylindroma
    • Fehr A, Kovacs A, Loning T, et al., The MYB-NFIB gene fusion-a novel genetic link between adenoid cystic carcinoma and dermal cylindroma. J Pathol 2011; 224: 322-327.
    • (2011) J Pathol , vol.224 , pp. 322-327
    • Fehr, A.1    Kovacs, A.2    Loning, T.3
  • 27
    • 84908867220 scopus 로고    scopus 로고
    • Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands
    • Weinreb I, Piscuoglio S, Martelotto LG, et al., Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nat Genet 2014; 46: 1166-1169.
    • (2014) Nat Genet , vol.46 , pp. 1166-1169
    • Weinreb, I.1    Piscuoglio, S.2    Martelotto, L.G.3
  • 28
    • 77949587649 scopus 로고    scopus 로고
    • Fast and accurate long-read alignment with Burrows-Wheeler transform
    • Li H, Durbin R,. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 2010; 26: 589-595.
    • (2010) Bioinformatics , vol.26 , pp. 589-595
    • Li, H.1    Durbin, R.2
  • 29
    • 77956295988 scopus 로고    scopus 로고
    • The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
    • McKenna A, Hanna M, Banks E, et al., The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010; 20: 1297-1303.
    • (2010) Genome Res , vol.20 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3
  • 30
    • 84874025843 scopus 로고    scopus 로고
    • Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
    • Cibulskis K, Lawrence MS, Carter SL, et al., Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat Biotechnol 2013; 31: 213-219.
    • (2013) Nat Biotechnol , vol.31 , pp. 213-219
    • Cibulskis, K.1    Lawrence, M.S.2    Carter, S.L.3
  • 31
    • 84863229597 scopus 로고    scopus 로고
    • VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
    • Koboldt DC, Zhang Q, Larson DE, et al., VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res 2012; 22: 568-576.
    • (2012) Genome Res , vol.22 , pp. 568-576
    • Koboldt, D.C.1    Zhang, Q.2    Larson, D.E.3
  • 32
    • 84864153492 scopus 로고    scopus 로고
    • Strelka: Accurate somatic small-variant calling from sequenced tumor-normal sample pairs
    • Saunders CT, Wong WS, Swamy S, et al., Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs. Bioinformatics 2012; 28: 1811-1817.
    • (2012) Bioinformatics , vol.28 , pp. 1811-1817
    • Saunders, C.T.1    Wong, W.S.2    Swamy, S.3
  • 33
    • 84921783122 scopus 로고    scopus 로고
    • Accurate de novo and transmitted indel detection in exome-capture data using microassembly
    • Narzisi G, O'Rawe JA, Iossifov I, et al., Accurate de novo and transmitted indel detection in exome-capture data using microassembly. Nat Methods 2014; 11: 1033-1036.
    • (2014) Nat Methods , vol.11 , pp. 1033-1036
    • Narzisi, G.1    O'Rawe, J.A.2    Iossifov, I.3
  • 34
    • 84875634162 scopus 로고    scopus 로고
    • Integrative Genomics Viewer (IGV): High-performance genomics data visualization and exploration
    • Thorvaldsdottir H, Robinson JT, Mesirov JP,. Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform 2013; 14: 178-192.
    • (2013) Brief Bioinform , vol.14 , pp. 178-192
    • Thorvaldsdottir, H.1    Robinson, J.T.2    Mesirov, J.P.3
  • 35
    • 77955151784 scopus 로고    scopus 로고
    • MutationTaster evaluates disease-causing potential of sequence alterations
    • Schwarz JM, Rodelsperger C, Schuelke M, et al., MutationTaster evaluates disease-causing potential of sequence alterations. Nat Methods 2010; 7: 575-576.
    • (2010) Nat Methods , vol.7 , pp. 575-576
    • Schwarz, J.M.1    Rodelsperger, C.2    Schuelke, M.3
  • 36
    • 69249115697 scopus 로고    scopus 로고
    • Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations
    • Carter H, Chen S, Isik L, et al., Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. Cancer Res 2009; 69: 6660-6667.
    • (2009) Cancer Res , vol.69 , pp. 6660-6667
    • Carter, H.1    Chen, S.2    Isik, L.3
  • 37
    • 84991233923 scopus 로고    scopus 로고
    • Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations
    • Martelotto LG, Ng C, De Filippo MR, et al., Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations. Genome Biol 2014; 15: 484.
    • (2014) Genome Biol , vol.15 , pp. 484
    • Martelotto, L.G.1    Ng, C.2    De Filippo, M.R.3
  • 38
    • 84876008750 scopus 로고    scopus 로고
    • The ConsensusPathDB interaction database: 2013 update
    • Kamburov A, Stelzl U, Lehrach H, et al., The ConsensusPathDB interaction database: 2013 update. Nucleic Acids Res 2013; 41: D793-800.
    • (2013) Nucleic Acids Res , vol.41 , pp. D793-D800
    • Kamburov, A.1    Stelzl, U.2    Lehrach, H.3
  • 39
    • 79955166265 scopus 로고    scopus 로고
    • GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
    • Mermel CH, Schumacher SE, Hill B, et al., GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol 2011; 12: R41.
    • (2011) Genome Biol , vol.12 , pp. R41
    • Mermel, C.H.1    Schumacher, S.E.2    Hill, B.3
  • 40
    • 84860782006 scopus 로고    scopus 로고
    • Absolute quantification of somatic DNA alterations in human cancer
    • Carter SL, Cibulskis K, Helman E, et al., Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol 2012; 30: 413-421.
    • (2012) Nat Biotechnol , vol.30 , pp. 413-421
    • Carter, S.L.1    Cibulskis, K.2    Helman, E.3
  • 41
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence MS, Stojanov P, Polak P, et al., Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 2013; 499: 214-218.
    • (2013) Nature , vol.499 , pp. 214-218
    • Lawrence, M.S.1    Stojanov, P.2    Polak, P.3
  • 43
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, et al., Mutational landscape and significance across 12 major cancer types. Nature 2013; 502: 333-339.
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3
  • 44
    • 84892833777 scopus 로고    scopus 로고
    • Discovery and saturation analysis of cancer genes across 21 tumour types
    • Lawrence MS, Stojanov P, Mermel CH, et al., Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 2014; 505: 495-501.
    • (2014) Nature , vol.505 , pp. 495-501
    • Lawrence, M.S.1    Stojanov, P.2    Mermel, C.H.3
  • 45
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • Gao J, Aksoy BA, Dogrusoz U, et al., Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013; 6: pl1.
    • (2013) Sci Signal , vol.6 , pp. pl1
    • Gao, J.1    Aksoy, B.A.2    Dogrusoz, U.3
  • 46
    • 77950866696 scopus 로고    scopus 로고
    • Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
    • Turner N, Lambros MB, Horlings HM, et al., Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets. Oncogene 2010; 29: 2013-2023.
    • (2010) Oncogene , vol.29 , pp. 2013-2023
    • Turner, N.1    Lambros, M.B.2    Horlings, H.M.3
  • 47
    • 0034885603 scopus 로고    scopus 로고
    • Novel DNA copy number losses in chromosome 12q12-q13 in adenoid cystic carcinoma
    • El-Rifai W, Rutherford S, Knuutila S, et al., Novel DNA copy number losses in chromosome 12q12-q13 in adenoid cystic carcinoma. Neoplasia 2001; 3: 173-178.
    • (2001) Neoplasia , vol.3 , pp. 173-178
    • El-Rifai, W.1    Rutherford, S.2    Knuutila, S.3
  • 48
    • 84890262841 scopus 로고    scopus 로고
    • Tackling the diversity of triple-negative breast cancer
    • Turner NC, Reis-Filho JS,. Tackling the diversity of triple-negative breast cancer. Clin Cancer Res 2013; 19: 6380-6388.
    • (2013) Clin Cancer Res , vol.19 , pp. 6380-6388
    • Turner, N.C.1    Reis-Filho, J.S.2
  • 49
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger M, Rowan AJ, Horswell S, et al., Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883-892.
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3
  • 50
    • 84907855592 scopus 로고    scopus 로고
    • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
    • de Bruin EC, McGranahan N, Mitter R, et al., Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science 2014; 346: 251-256.
    • (2014) Science , vol.346 , pp. 251-256
    • De Bruin, E.C.1    McGranahan, N.2    Mitter, R.3
  • 51
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov LB, Nik-Zainal S, Wedge DC, et al., Signatures of mutational processes in human cancer. Nature 2013; 500: 415-421.
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1    Nik-Zainal, S.2    Wedge, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.