AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia

Molecular and Cellular Biochemistry

Volumn 435, Issue 1-2, 2017, Pages 149-162

  Velagapudi, Ravikanth ^a,b   El Bakoush, Abdelmeneim ^a   Lepiarz, Izabela ^a   Ogunrinade, Folashade ^a   Olajide, Olumayokun A ^a  

^a UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

AMPK ; Neuroinflammation; ROS; SIRT1; Thymoquinone

Indexed keywords

ADENYLATE KINASE; DICHLORODIHYDROFLUORESCEIN DIACETATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN P40; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SIRTUIN 1; SMALL INTERFERING RNA; THYMOQUINONE; BENZOQUINONE DERIVATIVE; LIPOPOLYSACCHARIDE; SIRT1 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME MECHANISM; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MICROGLIA; MICROGLIAL CELL LINE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; RNA INTERFERENCE; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECT; ENZYMOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BENZOQUINONES; CELL LINE; ENZYME ACTIVATION; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; REACTIVE OXYGEN SPECIES; SIRTUIN 1;

EID: 85019657982     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-017-3064-3     Document Type: Article

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