메뉴 건너뛰기




Volumn 7, Issue , 2010, Pages

Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; NITRIC OXIDE; OXYGEN; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; CYBB PROTEIN, MOUSE; CYTOCHROME B; INTERLEUKIN 10; MEMBRANE PROTEIN; P22(PHOX) PROTEIN, MOUSE;

EID: 77954877602     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-7-41     Document Type: Article
Times cited : (157)

References (43)
  • 2
    • 0033789565 scopus 로고    scopus 로고
    • Free radical pathways in CNS injury
    • 10.1089/neu.2000.17.871, 11063054
    • Lewen A, Matz P, Chan PH. Free radical pathways in CNS injury. J Neurotrauma 2000, 17:871-890. 10.1089/neu.2000.17.871, 11063054.
    • (2000) J Neurotrauma , vol.17 , pp. 871-890
    • Lewen, A.1    Matz, P.2    Chan, P.H.3
  • 3
    • 0036316739 scopus 로고    scopus 로고
    • Local and systemic increase in lipid peroxidation after moderate experimental traumatic brain injury
    • 10.1046/j.0022-3042.2002.00777.x, 11948253
    • Pratico D, Reiss P, Tang LX, Sung S, Rokach J, McIntosh TK. Local and systemic increase in lipid peroxidation after moderate experimental traumatic brain injury. J Neurochem 2002, 80:894-898. 10.1046/j.0022-3042.2002.00777.x, 11948253.
    • (2002) J Neurochem , vol.80 , pp. 894-898
    • Pratico, D.1    Reiss, P.2    Tang, L.X.3    Sung, S.4    Rokach, J.5    McIntosh, T.K.6
  • 4
    • 0033793630 scopus 로고    scopus 로고
    • Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates
    • 10.1046/j.1471-4159.2000.0752178.x, 11032908
    • Tyurin VA, Tyurina YY, Borisenko GG, Sokolova TV, Ritov VB, Quinn PJ, Rose M, Kochanek P, Graham SH, Kagan VE. Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates. J Neurochem 2000, 75:2178-2189. 10.1046/j.1471-4159.2000.0752178.x, 11032908.
    • (2000) J Neurochem , vol.75 , pp. 2178-2189
    • Tyurin, V.A.1    Tyurina, Y.Y.2    Borisenko, G.G.3    Sokolova, T.V.4    Ritov, V.B.5    Quinn, P.J.6    Rose, M.7    Kochanek, P.8    Graham, S.H.9    Kagan, V.E.10
  • 5
    • 44349107522 scopus 로고    scopus 로고
    • Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model
    • 10.1038/jcbfm.2008.10, 18319733
    • Deng-Bryant Y, Singh IN, Carrico KM, Hall ED. Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model. J Cereb Blood Flow Metab 2008, 28:1114-1126. 10.1038/jcbfm.2008.10, 18319733.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1114-1126
    • Deng-Bryant, Y.1    Singh, I.N.2    Carrico, K.M.3    Hall, E.D.4
  • 6
    • 0035053188 scopus 로고    scopus 로고
    • Paradoxical increase in neuronal DNA fragmentation after neuroprotective free radical scavenger treatment in experimental traumatic brain injury
    • 10.1097/00004647-200104000-00003, 11323520
    • Lewen A, Skoglosa Y, Clausen F, Marklund N, Chan PH, Lindholm D, Hillered L. Paradoxical increase in neuronal DNA fragmentation after neuroprotective free radical scavenger treatment in experimental traumatic brain injury. J Cereb Blood Flow Metab 2001, 21:344-350. 10.1097/00004647-200104000-00003, 11323520.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 344-350
    • Lewen, A.1    Skoglosa, Y.2    Clausen, F.3    Marklund, N.4    Chan, P.H.5    Lindholm, D.6    Hillered, L.7
  • 7
    • 0026647763 scopus 로고
    • Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress
    • 10.1002/ana.410320706, 1510377
    • Floyd RA, Carney JM. Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann Neurol 1992, 32(Suppl):S22-27. 10.1002/ana.410320706, 1510377.
    • (1992) Ann Neurol , vol.32 , Issue.SUPPL
    • Floyd, R.A.1    Carney, J.M.2
  • 8
    • 33646380409 scopus 로고    scopus 로고
    • The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides
    • 10.1098/rstb.2005.1766, 1569597, 16321801
    • Abramov AY, Duchen MR. The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides. Philos Trans R Soc Lond B Biol Sci 2005, 360:2309-2314. 10.1098/rstb.2005.1766, 1569597, 16321801.
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 2309-2314
    • Abramov, A.Y.1    Duchen, M.R.2
  • 9
    • 33744960694 scopus 로고    scopus 로고
    • NADPH oxidases of the brain: distribution, regulation, and function
    • 10.1089/ars.2006.8.1583, 16987013
    • Infanger DW, Sharma RV, Davisson RL. NADPH oxidases of the brain: distribution, regulation, and function. Antioxid Redox Signal 2006, 8:1583-1596. 10.1089/ars.2006.8.1583, 16987013.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1583-1596
    • Infanger, D.W.1    Sharma, R.V.2    Davisson, R.L.3
  • 10
    • 8844227341 scopus 로고    scopus 로고
    • Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
    • 10.1161/01.RES.0000148637.85595.c5, 15499027
    • Kazama K, Anrather J, Zhou P, Girouard H, Frys K, Milner TA, Iadecola C. Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res 2004, 95:1019-1026. 10.1161/01.RES.0000148637.85595.c5, 15499027.
    • (2004) Circ Res , vol.95 , pp. 1019-1026
    • Kazama, K.1    Anrather, J.2    Zhou, P.3    Girouard, H.4    Frys, K.5    Milner, T.A.6    Iadecola, C.7
  • 11
    • 34547852400 scopus 로고    scopus 로고
    • NOX family NADPH oxidases: not just in mammals
    • 10.1016/j.biochi.2007.01.012, 17400358
    • Bedard K, Lardy B, Krause KH. NOX family NADPH oxidases: not just in mammals. Biochimie 2007, 89:1107-1112. 10.1016/j.biochi.2007.01.012, 17400358.
    • (2007) Biochimie , vol.89 , pp. 1107-1112
    • Bedard, K.1    Lardy, B.2    Krause, K.H.3
  • 14
    • 0042027784 scopus 로고    scopus 로고
    • A role for NOX NADPH oxidases in Alzheimer's disease and other types of dementia?
    • 10.1080/1521654031000153049, 12938732
    • Zekry D, Epperson TK, Krause KH. A role for NOX NADPH oxidases in Alzheimer's disease and other types of dementia?. IUBMB Life 2003, 55:307-313. 10.1080/1521654031000153049, 12938732.
    • (2003) IUBMB Life , vol.55 , pp. 307-313
    • Zekry, D.1    Epperson, T.K.2    Krause, K.H.3
  • 15
    • 0031570504 scopus 로고    scopus 로고
    • Mice lacking reduced nicotinamide adenine dinucleotide phosphate oxidase activity show increased susceptibility to early infection with Listeria monocytogenes
    • Dinauer MC, Deck MB, Unanue ER. Mice lacking reduced nicotinamide adenine dinucleotide phosphate oxidase activity show increased susceptibility to early infection with Listeria monocytogenes. J Immunol 1997, 158:5581-5583.
    • (1997) J Immunol , vol.158 , pp. 5581-5583
    • Dinauer, M.C.1    Deck, M.B.2    Unanue, E.R.3
  • 16
    • 77955513860 scopus 로고    scopus 로고
    • Expression and Localization of Pituitary Adenylate Cyclase-Activating Polypeptide-Specific Receptor (PAC1R)..After Traumatic Brain Injury in Mice
    • Morikawa K, Dohi K, Yofu S, Mihara Y, Nakamachi T, Ohtaki H, Shioda S, Aruga T. Expression and Localization of Pituitary Adenylate Cyclase-Activating Polypeptide-Specific Receptor (PAC1R)..After Traumatic Brain Injury in Mice. Open Crit Care Med J 2008, 1:33-38.
    • (2008) Open Crit Care Med J , vol.1 , pp. 33-38
    • Morikawa, K.1    Dohi, K.2    Yofu, S.3    Mihara, Y.4    Nakamachi, T.5    Ohtaki, H.6    Shioda, S.7    Aruga, T.8
  • 17
    • 69949140066 scopus 로고    scopus 로고
    • The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation
    • Henn A, Lund S, Hedtjarn M, Schrattenholz A, Porzgen P, Leist M. The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation. Altex 2009, 26:83-94.
    • (2009) Altex , vol.26 , pp. 83-94
    • Henn, A.1    Lund, S.2    Hedtjarn, M.3    Schrattenholz, A.4    Porzgen, P.5    Leist, M.6
  • 18
    • 0032561317 scopus 로고    scopus 로고
    • Mutation at histidine 338 of gp91(phox) depletes FAD and affects expression of cytochrome b558 of the human NADPH oxidase
    • 10.1074/jbc.273.43.27879, 9774399
    • Yoshida LS, Saruta F, Yoshikawa K, Tatsuzawa O, Tsunawaki S. Mutation at histidine 338 of gp91(phox) depletes FAD and affects expression of cytochrome b558 of the human NADPH oxidase. J Biol Chem 1998, 273:27879-27886. 10.1074/jbc.273.43.27879, 9774399.
    • (1998) J Biol Chem , vol.273 , pp. 27879-27886
    • Yoshida, L.S.1    Saruta, F.2    Yoshikawa, K.3    Tatsuzawa, O.4    Tsunawaki, S.5
  • 19
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine
    • Bindokas VP, Jordan J, Lee CC, Miller RJ. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 1996, 16:1324-1336.
    • (1996) J Neurosci , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1    Jordan, J.2    Lee, C.C.3    Miller, R.J.4
  • 20
    • 0037265240 scopus 로고    scopus 로고
    • Rnative activation of macrophages
    • 10.1038/nri978, 12511873
    • Gordon S. rnative activation of macrophages. Nat Rev Immunol 2003, 3:23-35. 10.1038/nri978, 12511873.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 21
    • 0027934360 scopus 로고
    • Determination of arginase activity in macrophages: a micromethod
    • 10.1016/0022-1759(94)90027-2, 8083527
    • Corraliza I, Campo M, Soler G, Modolell M. Determination of arginase activity in macrophages: a micromethod. J Immunol Methods 1994, 174:231-235. 10.1016/0022-1759(94)90027-2, 8083527.
    • (1994) J Immunol Methods , vol.174 , pp. 231-235
    • Corraliza, I.1    Campo, M.2    Soler, G.3    Modolell, M.4
  • 22
    • 0142011158 scopus 로고    scopus 로고
    • NADPH oxidase immunoreactivity in the mouse brain
    • 10.1016/S0006-8993(03)03364-X, 14519542
    • Serrano F, Kolluri NS, Wientjes FB, Card JP, Klann E. NADPH oxidase immunoreactivity in the mouse brain. Brain Res 2003, 988:193-198. 10.1016/S0006-8993(03)03364-X, 14519542.
    • (2003) Brain Res , vol.988 , pp. 193-198
    • Serrano, F.1    Kolluri, N.S.2    Wientjes, F.B.3    Card, J.P.4    Klann, E.5
  • 24
    • 65349159768 scopus 로고    scopus 로고
    • Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice
    • 10.1111/j.1476-5381.2008.00073.x, 2697707, 19175604
    • Jackman KA, Miller AA, De Silva TM, Crack PJ, Drummond GR, Sobey CG. Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice. Br J Pharmacol 2009, 156:680-688. 10.1111/j.1476-5381.2008.00073.x, 2697707, 19175604.
    • (2009) Br J Pharmacol , vol.156 , pp. 680-688
    • Jackman, K.A.1    Miller, A.A.2    De Silva, T.M.3    Crack, P.J.4    Drummond, G.R.5    Sobey, C.G.6
  • 25
    • 24144490399 scopus 로고    scopus 로고
    • Role of NADPH oxidase in the brain injury of intracerebral hemorrhage
    • 10.1111/j.1471-4159.2005.03292.x, 16011743
    • Tang J, Liu J, Zhou C, Ostanin D, Grisham MB, Neil Granger D, Zhang JH. Role of NADPH oxidase in the brain injury of intracerebral hemorrhage. J Neurochem 2005, 94:1342-1350. 10.1111/j.1471-4159.2005.03292.x, 16011743.
    • (2005) J Neurochem , vol.94 , pp. 1342-1350
    • Tang, J.1    Liu, J.2    Zhou, C.3    Ostanin, D.4    Grisham, M.B.5    Neil Granger, D.6    Zhang, J.H.7
  • 26
    • 34948869744 scopus 로고    scopus 로고
    • Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells
    • 10.1016/j.neuro.2007.08.008, 2140261, 17904225
    • Anantharam V, Kaul S, Song C, Kanthasamy A, Kanthasamy AG. Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells. Neurotoxicology 2007, 28:988-997. 10.1016/j.neuro.2007.08.008, 2140261, 17904225.
    • (2007) Neurotoxicology , vol.28 , pp. 988-997
    • Anantharam, V.1    Kaul, S.2    Song, C.3    Kanthasamy, A.4    Kanthasamy, A.G.5
  • 27
    • 0034617071 scopus 로고    scopus 로고
    • A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • Gorlach A, Brandes RP, Nguyen K, Amidi M, Dehghani F, Busse R. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ Res 2000, 87:26-32.
    • (2000) Circ Res , vol.87 , pp. 26-32
    • Gorlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Dehghani, F.5    Busse, R.6
  • 28
    • 13844299146 scopus 로고    scopus 로고
    • Localization of NADPH oxidase subunits in neonatal sympathetic neurons
    • 10.1016/j.neulet.2004.11.066, 15722179
    • Hilburger EW, Conte EJ, McGee DW, Tammariello SP. Localization of NADPH oxidase subunits in neonatal sympathetic neurons. Neurosci Lett 2005, 377:16-19. 10.1016/j.neulet.2004.11.066, 15722179.
    • (2005) Neurosci Lett , vol.377 , pp. 16-19
    • Hilburger, E.W.1    Conte, E.J.2    McGee, D.W.3    Tammariello, S.P.4
  • 29
    • 33748326080 scopus 로고    scopus 로고
    • NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke
    • 10.1016/j.brainres.2006.06.082, 16879806
    • Miller AA, Dusting GJ, Roulston CL, Sobey CG. NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain Res 2006, 1111:111-116. 10.1016/j.brainres.2006.06.082, 16879806.
    • (2006) Brain Res , vol.1111 , pp. 111-116
    • Miller, A.A.1    Dusting, G.J.2    Roulston, C.L.3    Sobey, C.G.4
  • 30
    • 0035050997 scopus 로고    scopus 로고
    • Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation
    • 10.1097/00004647-200104000-00006, 11323523
    • Green SP, Cairns B, Rae J, Errett-Baroncini C, Hongo JA, Erickson RW, Curnutte JT. Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation. J Cereb Blood Flow Metab 2001, 21:374-384. 10.1097/00004647-200104000-00006, 11323523.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 374-384
    • Green, S.P.1    Cairns, B.2    Rae, J.3    Errett-Baroncini, C.4    Hongo, J.A.5    Erickson, R.W.6    Curnutte, J.T.7
  • 31
    • 33748454440 scopus 로고    scopus 로고
    • A key role for the microglial NADPH oxidase in APP-dependent killing of neurons
    • 10.1016/j.neurobiolaging.2005.09.036, 16260066
    • Qin B, Cartier L, Dubois-Dauphin M, Li B, Serrander L, Krause KH. A key role for the microglial NADPH oxidase in APP-dependent killing of neurons. Neurobiol Aging 2006, 27:1577-1587. 10.1016/j.neurobiolaging.2005.09.036, 16260066.
    • (2006) Neurobiol Aging , vol.27 , pp. 1577-1587
    • Qin, B.1    Cartier, L.2    Dubois-Dauphin, M.3    Li, B.4    Serrander, L.5    Krause, K.H.6
  • 32
    • 0028797945 scopus 로고
    • In vivo detection of superoxide anion production by the brain using a cytochrome c electrode
    • Fabian RH, DeWitt DS, Kent TA. In vivo detection of superoxide anion production by the brain using a cytochrome c electrode. J Cereb Blood Flow Metab 1995, 15:242-247.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 242-247
    • Fabian, R.H.1    DeWitt, D.S.2    Kent, T.A.3
  • 33
    • 33747137966 scopus 로고    scopus 로고
    • Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy
    • 10.1038/sj.jcbfm.9600297, 16538231
    • Singh IN, Sullivan PG, Deng Y, Mbye LH, Hall ED. Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy. J Cereb Blood Flow Metab 2006, 26:1407-1418. 10.1038/sj.jcbfm.9600297, 16538231.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1407-1418
    • Singh, I.N.1    Sullivan, P.G.2    Deng, Y.3    Mbye, L.H.4    Hall, E.D.5
  • 34
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • 10.1038/nrn2038, 17180163
    • Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007, 8:57-69. 10.1038/nrn2038, 17180163.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 35
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • 10.1038/nn1997, 17965659
    • Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007, 10:1387-1394. 10.1038/nn1997, 17965659.
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 36
    • 33747877627 scopus 로고    scopus 로고
    • Microglial senescence: does the brain's immune system have an expiration date?
    • 10.1016/j.tins.2006.07.001, 16859761
    • Streit WJ. Microglial senescence: does the brain's immune system have an expiration date?. Trends Neurosci 2006, 29:506-510. 10.1016/j.tins.2006.07.001, 16859761.
    • (2006) Trends Neurosci , vol.29 , pp. 506-510
    • Streit, W.J.1
  • 37
    • 55749098498 scopus 로고    scopus 로고
    • Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses
    • 10.1073/pnas.0803670105, 2567180, 18794523
    • Ohtaki H, Ylostalo JH, Foraker JE, Robinson AP, Reger RL, Shioda S, Prockop DJ. Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proc Natl Acad Sci USA 2008, 105:14638-14643. 10.1073/pnas.0803670105, 2567180, 18794523.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14638-14643
    • Ohtaki, H.1    Ylostalo, J.H.2    Foraker, J.E.3    Robinson, A.P.4    Reger, R.L.5    Shioda, S.6    Prockop, D.J.7
  • 38
    • 0034635447 scopus 로고    scopus 로고
    • Neuroprotection by LY341122, a novel inhibitor of lipid peroxidation, against focal ischemic brain damage in rats
    • 10.1016/S0014-2999(99)00768-2, 10686299
    • Huh PW, Belayev L, Zhao W, Clemens JA, Panetta JA, Busto R, Ginsberg MD. Neuroprotection by LY341122, a novel inhibitor of lipid peroxidation, against focal ischemic brain damage in rats. Eur J Pharmacol 2000, 389:79-88. 10.1016/S0014-2999(99)00768-2, 10686299.
    • (2000) Eur J Pharmacol , vol.389 , pp. 79-88
    • Huh, P.W.1    Belayev, L.2    Zhao, W.3    Clemens, J.A.4    Panetta, J.A.5    Busto, R.6    Ginsberg, M.D.7
  • 39
    • 47149098182 scopus 로고    scopus 로고
    • NOX enzymes as novel targets for drug development
    • 10.1007/s00281-008-0123-6, 18509646
    • Lambeth JD, Krause KH, Clark RA. NOX enzymes as novel targets for drug development. Semin Immunopathol 2008, 30:339-363. 10.1007/s00281-008-0123-6, 18509646.
    • (2008) Semin Immunopathol , vol.30 , pp. 339-363
    • Lambeth, J.D.1    Krause, K.H.2    Clark, R.A.3
  • 40
    • 35649015344 scopus 로고    scopus 로고
    • NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke
    • 10.1161/STROKEAHA.107.489765, 17916764
    • Kahles T, Luedike P, Endres M, Galla HJ, Steinmetz H, Busse R, Neumann-Haefelin T, Brandes RP. NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke. Stroke 2007, 38:3000-3006. 10.1161/STROKEAHA.107.489765, 17916764.
    • (2007) Stroke , vol.38 , pp. 3000-3006
    • Kahles, T.1    Luedike, P.2    Endres, M.3    Galla, H.J.4    Steinmetz, H.5    Busse, R.6    Neumann-Haefelin, T.7    Brandes, R.P.8
  • 41
    • 24144490399 scopus 로고    scopus 로고
    • Role of NADPH oxidase in the brain injury of intracerebral hemorrhage
    • 10.1111/j.1471-4159.2005.03292.x, 16011743
    • Tang J, Liu J, Zhou C, Ostanin D, Grisham MB, Granger DN, Zhang JH. Role of NADPH oxidase in the brain injury of intracerebral hemorrhage. J Neurochem 2005, 94:1342-1350. 10.1111/j.1471-4159.2005.03292.x, 16011743.
    • (2005) J Neurochem , vol.94 , pp. 1342-1350
    • Tang, J.1    Liu, J.2    Zhou, C.3    Ostanin, D.4    Grisham, M.B.5    Granger, D.N.6    Zhang, J.H.7
  • 42
    • 33847214852 scopus 로고    scopus 로고
    • NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury
    • 10.1016/j.neulet.2006.12.055, 1857328, 17317004
    • Lo W, Bravo T, Jadhav V, Titova E, Zhang JH, Tang J. NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury. Neurosci Lett 2007, 414:228-232. 10.1016/j.neulet.2006.12.055, 1857328, 17317004.
    • (2007) Neurosci Lett , vol.414 , pp. 228-232
    • Lo, W.1    Bravo, T.2    Jadhav, V.3    Titova, E.4    Zhang, J.H.5    Tang, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.