Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants

Science Translational Medicine

Volumn 9, Issue 389, 2017, Pages

  Karnes, Jason H ^a   Bastarache, Lisa ^b   Shaffer, Christian M ^b   Gaudieri, Silvana ^b,c,d   Xu, Yaomin ^b,e   Glazer, Andrew M ^b   Mosley, Jonathan D ^b   Zhao, Shilin ^b   Raychaudhuri, Soumya ^f,g,h,i,j   Mallal, Simon ^b,d,e   Ye, Zhan ^k   Mayer, John G ^k   Brilliant, Murray H ^k   Hebbring, Scott J ^k   Roden, Dan M ^b,e   Phillips, Elizabeth J ^b,e   Denny, Joshua C ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d MURDOCH UNIVERSITY   (Australia)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h LABORATORY FOR MOLECULAR MEDICINE   (United States)

ⁱ UNIVERSITY OF MANCHESTER   (United Kingdom)

^j KAROLINSKA INSTITUTE   (Sweden)

^k MARSHFIELD CLINIC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DPB1 ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA-DQB1 ANTIGEN;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION STUDY; GENETIC VARIABILITY; HLAA GENE; HLAB GENE; HLAC GENE; HLADPA1 GENE; HLADPB1 GENE; HLADQA1 GENE; HLADQB1 GENE; HLADRB1 GENE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PHENOME WIDE ASSOCIATION STUDY; PHENOTYPE; POPULATION RESEARCH; PRIORITY JOURNAL; PSORIASIS; PSORIASIS VULGARIS; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY;

ALLELES; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DQ BETA-CHAINS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 85019257454     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aai8708     Document Type: Article

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