The amino acid variation within the binding pocket 7 and 9 ofHLA-DRB1 molecules are associated with primary Sjögren's syndrome

Journal of Autoimmunity

Volumn 57, Issue , 2015, Pages 53-59

  Huang, Renliang ^a   Yin, Junping ^a   Chen, Yan ^a   Deng, Fengyuan ^a   Chen, Juan ^d   Gao, Xing ^e   Liu, Zuguo ^a   Yu, Xinhua ^a,b,c   Zheng, Junfeng ^a,d  

^a XIAMEN UNIVERSITY   (China)

^b RESEARCH CENTER BORSTEL   (Germany)

^c JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^d THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^e XIAMEN UNIVERSITY   (China)

Author keywords

Autoimmunity; HLA; Homology modeling; Peptide binding groove; Sj gren's syndrome

Indexed keywords

AMINO ACID; HLA DRB1 ANTIGEN;

ADULT; ALLELE; ARTICLE; BINDING SITE; CHINESE; CONTROLLED STUDY; EXON; FEMALE; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SJOEGREN SYNDROME; CHEMICAL STRUCTURE; CHEMISTRY; DNA SEQUENCE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; META ANALYSIS (TOPIC); METABOLISM; MIDDLE AGED; PROTEIN TERTIARY STRUCTURE;

ADULT; ALLELES; AMINO ACIDS; BINDING SITES; EXONS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HLA-DRB1 CHAINS; HUMANS; MALE; META-ANALYSIS AS TOPIC; MIDDLE AGED; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; SJOGREN'S SYNDROME;

EID: 84922925629     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2014.11.006     Document Type: Article

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