Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation

Cell Reports

Volumn 19, Issue 6, 2017, Pages 1151-1164

  Shinozaki, Youichi ^a   Shibata, Keisuke ^a   Yoshida, Keitaro ^b   Shigetomi, Eiji ^a   Gachet, Christian ^c   Ikenaka, Kazuhiro ^d   Tanaka, Kenji F ^b   Koizumi, Schuichi ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c INSERM   (France)

^d NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

astrocyte scar; astrocytes; ATP; cytokines; microglia; neuroprotection; P2Y1 receptors; purinergic signal; traumatic brain injury

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; PURINERGIC P2Y1 RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; CELL INTERACTION; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRODIALYSIS; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCAR FORMATION; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; CELL CULTURE; CYTOLOGY; GENETICS; GLIOSIS; METABOLISM; NERVE REGENERATION; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ASTROCYTES; BRAIN INJURIES, TRAUMATIC; CELL COMMUNICATION; CELLS, CULTURED; CYTOKINES; DOWN-REGULATION; GLIOSIS; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; NERVE REGENERATION; PHENOTYPE; RECEPTORS, PURINERGIC P2Y1;

EID: 85019231007     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.04.047     Document Type: Article

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