메뉴 건너뛰기




Volumn 6, Issue , 2017, Pages

Liver fat: A relevant target for dietary intervention? Summary of a unilever workshop

Author keywords

Cardiovascular disease; Diet; Liver fat; Type 2 diabetes

Indexed keywords

ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DIETITIAN; DISEASE ASSESSMENT; DISEASE COURSE; FAT INTAKE; FOOD INDUSTRY; HUMAN; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; LIPOGENESIS; LIVER CIRRHOSIS; LIVER WEIGHT; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; OUTCOME ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RISK FACTOR; RISK REDUCTION;

EID: 85018442980     PISSN: 20486790     EISSN: None     Source Type: Journal    
DOI: 10.1017/jns.2017.13     Document Type: Article
Times cited : (11)

References (120)
  • 1
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-Alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • Chalasani N, Younossi Z, Lavine JE, et al. (2012) The diagnosis and management of non-Alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 55, 2005-2023.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3
  • 2
    • 84943540060 scopus 로고    scopus 로고
    • Mechanistic link between nonalcoholic fatty liver disease and cardiometabolic disorders
    • Lim S, Oh TJ & Koh KK (2015) Mechanistic link between nonalcoholic fatty liver disease and cardiometabolic disorders. Int J Cardiol 201, 408-414.
    • (2015) Int J Cardiol , vol.201 , pp. 408-414
    • Lim, S.1    Oh, T.J.2    Koh, K.K.3
  • 3
    • 80555136061 scopus 로고    scopus 로고
    • Meta-Analysis: Natural history of non-Alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • Musso G, Gambino R, Cassader M, et al. (2011) Meta-Analysis: natural history of non-Alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 43, 617-649.
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 4
    • 84873637593 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A novel cardiometabolic risk factor for type 2 diabetes and its complications
    • Targher G & Byrne CD (2013) Nonalcoholic fatty liver disease: A novel cardiometabolic risk factor for type 2 diabetes and its complications. J Clin Endocrinol Metab 98, 483-495.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 483-495
    • Targher, G.1    Byrne, C.D.2
  • 5
    • 77957375969 scopus 로고    scopus 로고
    • Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease
    • Targher G, Day CP & Bonora E (2010) Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. New Engl J Med 363, 1341-1350.
    • (2010) New Engl J Med , vol.363 , pp. 1341-1350
    • Targher, G.1    Day, C.P.2    Bonora, E.3
  • 6
    • 84922622191 scopus 로고    scopus 로고
    • A concise review of nonalcoholic fatty liver disease
    • Than NN & Newsome PN (2015) A concise review of nonalcoholic fatty liver disease. Atherosclerosis 239, 192-202.
    • (2015) Atherosclerosis , vol.239 , pp. 192-202
    • Than, N.N.1    Newsome, P.N.2
  • 8
    • 0032960890 scopus 로고    scopus 로고
    • Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects
    • Jacob S, Machann J, Rett K, et al. (1999) Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 48, 1113-1119.
    • (1999) Diabetes , vol.48 , pp. 1113-1119
    • Jacob, S.1    Machann, J.2    Rett, K.3
  • 9
    • 84919609004 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein
    • Lindeboom L, Nabuurs CI, Hesselink MKC, et al. (2015) Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein. Am J Clin Nutr 101, 65-71.
    • (2015) Am J Clin Nutr , vol.101 , pp. 65-71
    • Lindeboom, L.1    Nabuurs, C.I.2    Hesselink, M.K.C.3
  • 10
    • 84885954106 scopus 로고    scopus 로고
    • Variability in fasting lipid and glycogen contents in hepatic and skeletal muscle tissue in subjects with and without type 2 diabetes: A 1H and 13C MRS study
    • Stephenson MC, Leverton E, Khoo EYH, et al. (2013) Variability in fasting lipid and glycogen contents in hepatic and skeletal muscle tissue in subjects with and without type 2 diabetes: A 1H and 13C MRS study. NMR Biomed 26, 1518-1526.
    • (2013) NMR Biomed , vol.26 , pp. 1518-1526
    • Stephenson, M.C.1    Leverton, E.2    Khoo, E.Y.H.3
  • 11
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: Prevalence of hepatic steatosis in the general population
    • Szczepaniak LS, Nurenberg P, Leonard D, et al. (2005) Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 288, E462-E468.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E462-E468
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3
  • 12
    • 84860297671 scopus 로고    scopus 로고
    • Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: A randomized controlled trial
    • Bjermo H, Iggman D, Kullberg J, et al. (2012) Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: A randomized controlled trial. Am J Clin Nutr 95, 1003-1012.
    • (2012) Am J Clin Nutr , vol.95 , pp. 1003-1012
    • Bjermo, H.1    Iggman, D.2    Kullberg, J.3
  • 13
    • 84862885081 scopus 로고    scopus 로고
    • Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients
    • Bozzetto L, Prinster A, Annuzzi G, et al. (2012) Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients. Diabetes Care 35, 1429-1435.
    • (2012) Diabetes Care , vol.35 , pp. 1429-1435
    • Bozzetto, L.1    Prinster, A.2    Annuzzi, G.3
  • 14
    • 79955107467 scopus 로고    scopus 로고
    • Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects
    • Haufe S, Engeli S, Kast P, et al. (2011) Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects. Hepatology 53, 1504-1514.
    • (2011) Hepatology , vol.53 , pp. 1504-1514
    • Haufe, S.1    Engeli, S.2    Kast, P.3
  • 15
    • 84903207987 scopus 로고    scopus 로고
    • Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans
    • Rosqvist F, Iggman D, Kullberg J, et al. (2014) Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans. Diabetes 63, 2356-2368.
    • (2014) Diabetes , vol.63 , pp. 2356-2368
    • Rosqvist, F.1    Iggman, D.2    Kullberg, J.3
  • 16
    • 80051979813 scopus 로고    scopus 로고
    • Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence
    • Zelber-Sagi S, Ratziu V & Oren R (2011) Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence. World J Gastroenterol 17, 3377-3389.
    • (2011) World J Gastroenterol , vol.17 , pp. 3377-3389
    • Zelber-Sagi, S.1    Ratziu, V.2    Oren, R.3
  • 17
    • 0037371754 scopus 로고    scopus 로고
    • Myocardial triglycerides and systolic function in humans: In vivo evaluation by localized proton spectroscopy and cardiac imaging
    • Szczepaniak LS, Dobbins RL, Metzger GJ, et al. (2003) Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging. Magn Reson Med 49, 417-423.
    • (2003) Magn Reson Med , vol.49 , pp. 417-423
    • Szczepaniak, L.S.1    Dobbins, R.L.2    Metzger, G.J.3
  • 18
    • 7444227405 scopus 로고    scopus 로고
    • Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects
    • Thamer C, Machann J, Haap M, et al. (2004) Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects. Diabetes Care 27, 2726-2729.
    • (2004) Diabetes Care , vol.27 , pp. 2726-2729
    • Thamer, C.1    Machann, J.2    Haap, M.3
  • 19
    • 33748485573 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor-γ coactivator-1 and insulin resistance: Acute effect of fatty acids
    • Hoeks J, Hesselink MKC, Russell AP, et al. (2006) Peroxisome proliferator-Activated receptor-γ coactivator-1 and insulin resistance: Acute effect of fatty acids. Diabetologia 49, 2419-2426.
    • (2006) Diabetologia , vol.49 , pp. 2419-2426
    • Hoeks, J.1    Hesselink, M.K.C.2    Russell, A.P.3
  • 20
    • 79957829995 scopus 로고    scopus 로고
    • Exercise-induced modulation of cardiac lipid content in healthy lean young men
    • Bilet L, Van De Weijer T, Hesselink MKC, et al. (2011) Exercise-induced modulation of cardiac lipid content in healthy lean young men. Basic Res Cardiol 106, 307-315.
    • (2011) Basic Res Cardiol , vol.106 , pp. 307-315
    • Bilet, L.1    Van De Weijer, T.2    Hesselink, M.K.C.3
  • 21
    • 84927625398 scopus 로고    scopus 로고
    • Acute exercise does not decrease liver fat in men with overweight or NAFLD
    • Bilet L, Brouwers B, Van Ewijk PA, et al. (2015) Acute exercise does not decrease liver fat in men with overweight or NAFLD. Sci Rep 5, 9709.
    • (2015) Sci Rep , vol.5 , pp. 9709
    • Bilet, L.1    Brouwers, B.2    Van Ewijk, P.A.3
  • 22
    • 77951646335 scopus 로고    scopus 로고
    • Improved ejection fraction after exercise training in obesity is accompanied by reduced cardiac lipid content
    • Schrauwen-Hinderling VB, Hesselink MKC, Meex R, et al. (2010) Improved ejection fraction after exercise training in obesity is accompanied by reduced cardiac lipid content. J Clin Endocrinol Metab 95, 1932-1938.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1932-1938
    • Schrauwen-Hinderling, V.B.1    Hesselink, M.K.C.2    Meex, R.3
  • 23
    • 84931577976 scopus 로고    scopus 로고
    • Effect of aerobic exercise training dose on liver fat and visceral adiposity
    • Keating SE, Hackett DA, Parker HM, et al. (2015) Effect of aerobic exercise training dose on liver fat and visceral adiposity. J Hepatol 63, 174-182.
    • (2015) J Hepatol , vol.63 , pp. 174-182
    • Keating, S.E.1    Hackett, D.A.2    Parker, H.M.3
  • 24
    • 83555176039 scopus 로고    scopus 로고
    • Lifestyle interventions for the treatment of non-Alcoholic fatty liver disease in adults: A systematic review
    • Thoma C, Day CP & Trenell MI (2012) Lifestyle interventions for the treatment of non-Alcoholic fatty liver disease in adults: A systematic review. J Hepatol 56, 255-266.
    • (2012) J Hepatol , vol.56 , pp. 255-266
    • Thoma, C.1    Day, C.P.2    Trenell, M.I.3
  • 25
    • 80455143206 scopus 로고    scopus 로고
    • Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
    • Timmers S, Konings E, Bilet L, et al. (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14, 612-622.
    • (2011) Cell Metab , vol.14 , pp. 612-622
    • Timmers, S.1    Konings, E.2    Bilet, L.3
  • 26
    • 0037684703 scopus 로고    scopus 로고
    • The increase in intramyocellular lipid content is a very early response to training
    • Schrauwen-Hinderling VB, Schrauwen P, Hesselink MKC, et al. (2003) The increase in intramyocellular lipid content is a very early response to training. J Clin Endocrinol Metab 88, 1610-1616.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1610-1616
    • Schrauwen-Hinderling, V.B.1    Schrauwen, P.2    Hesselink, M.K.C.3
  • 27
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurancetrained athletes
    • Goodpaster BH, He J, Watkins S, et al. (2001) Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurancetrained athletes. J Clin Endocrinol Metabol 86, 5755-5761.
    • (2001) J Clin Endocrinol Metabol , vol.86 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3
  • 28
    • 84943262988 scopus 로고    scopus 로고
    • Liver perilipin 5 expression worsens hepatosteatosis but not insulin resistance in high fat-fed mice
    • Trevino MB, Mazur-Hart D, Machida Y, et al. (2015) Liver perilipin 5 expression worsens hepatosteatosis but not insulin resistance in high fat-fed mice. Mol Endocrinol 29, 1414-1425.
    • (2015) Mol Endocrinol , vol.29 , pp. 1414-1425
    • Trevino, M.B.1    Mazur-Hart, D.2    Machida, Y.3
  • 29
    • 70449753788 scopus 로고    scopus 로고
    • SnapShot: Lipid droplets
    • Krahmer N, Guo Y, Farese J, et al. (2009) SnapShot: lipid droplets. Cell 139, 1024.
    • (2009) Cell , vol.139 , pp. 1024
    • Krahmer, N.1    Guo, Y.2    Farese, J.3
  • 30
    • 33750606061 scopus 로고    scopus 로고
    • Long-Term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzén LE, Mathiesen UL, et al. (2006) Long-Term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 44, 865-873.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzén, L.E.2    Mathiesen, U.L.3
  • 31
    • 79960029926 scopus 로고    scopus 로고
    • Systematic review: The epidemiology and natural history of non-Alcoholic fatty liver disease and non-Alcoholic steatohepatitis in adults
    • Vernon G, Baranova A & Younossi ZM (2011) Systematic review: The epidemiology and natural history of non-Alcoholic fatty liver disease and non-Alcoholic steatohepatitis in adults. Alim Pharmacol Ther 34, 274-285.
    • (2011) Alim Pharmacol Ther , vol.34 , pp. 274-285
    • Vernon, G.1    Baranova, A.2    Younossi, Z.M.3
  • 32
    • 0242443339 scopus 로고    scopus 로고
    • Prevalence and predictors of asymptomatic liver disease in patients undergoing gastric bypass surgery
    • Beymer C, Kowdley KV, Larson A, et al. (2003) Prevalence and predictors of asymptomatic liver disease in patients undergoing gastric bypass surgery. Arch Surg 138, 1240-1244.
    • (2003) Arch Surg , vol.138 , pp. 1240-1244
    • Beymer, C.1    Kowdley, K.V.2    Larson, A.3
  • 33
    • 24744437499 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease in young adult severely obese non-diabetic patients in South Italy
    • Colicchio P, Tarantino G, Del GF, et al. (2005) Non-Alcoholic fatty liver disease in young adult severely obese non-diabetic patients in South Italy. Ann Nutr Metab 49, 289-295.
    • (2005) Ann Nutr Metab , vol.49 , pp. 289-295
    • Colicchio, P.1    Tarantino, G.2    Del, G.F.3
  • 34
    • 11144280457 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease -A common and benign finding in octogenarian patients
    • Kagansky N, Levy S, Keter D, et al. (2004) Non-Alcoholic fatty liver disease -A common and benign finding in octogenarian patients. Liver Int 24, 588-594.
    • (2004) Liver Int , vol.24 , pp. 588-594
    • Kagansky, N.1    Levy, S.2    Keter, D.3
  • 35
    • 57749183469 scopus 로고    scopus 로고
    • Prevalence and associated factors of non-Alcoholic fatty liver disease in patients with type-2 diabetes mellitus
    • Leite NC, Salles GF, Araujo ALE, et al. (2009) Prevalence and associated factors of non-Alcoholic fatty liver disease in patients with type-2 diabetes mellitus. Liver Int 29, 113-119.
    • (2009) Liver Int , vol.29 , pp. 113-119
    • Leite, N.C.1    Salles, G.F.2    Araujo, A.L.E.3
  • 36
    • 33748110788 scopus 로고    scopus 로고
    • Hepatic histology in obese patients undergoing bariatric surgery
    • Machado M, Marques-Vidal P & Cortez-Pinto H (2006) Hepatic histology in obese patients undergoing bariatric surgery. J Hepatol 45, 600-606.
    • (2006) J Hepatol , vol.45 , pp. 600-606
    • Machado, M.1    Marques-Vidal, P.2    Cortez-Pinto, H.3
  • 37
    • 67650496665 scopus 로고    scopus 로고
    • Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort
    • Wagenknecht LE, Scherzinger AL, Stamm ER, et al. (2009) Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort. Obesity 17, 1240-1246.
    • (2009) Obesity , vol.17 , pp. 1240-1246
    • Wagenknecht, L.E.1    Scherzinger, A.L.2    Stamm, E.R.3
  • 38
    • 33750002388 scopus 로고    scopus 로고
    • Prevalence of fatty liver in children and adolescents
    • Schwimmer JB, Deutsch R, Kahen T, et al. (2006) Prevalence of fatty liver in children and adolescents. Pediatrics 118, 1388-1393.
    • (2006) Pediatrics , vol.118 , pp. 1388-1393
    • Schwimmer, J.B.1    Deutsch, R.2    Kahen, T.3
  • 39
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    • Adams LA, Lymp JF, Sauver J, et al. (2005) The natural history of nonalcoholic fatty liver disease: A population-based cohort study. Gastroenterology 129, 113-121.
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    Sauver, J.3
  • 40
    • 17144387889 scopus 로고    scopus 로고
    • Hepatic steatosis is associated with an increased risk of carotid atherosclerosis
    • Völzke H, Robinson DM, Kleine V, et al. (2005) Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World J Gastroenterol 11, 1848-1853.
    • (2005) World J Gastroenterol , vol.11 , pp. 1848-1853
    • Völzke, H.1    Robinson, D.M.2    Kleine, V.3
  • 41
    • 84904908862 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease
    • Sattar N (2014) Non-Alcoholic fatty liver disease. BMJ 349, g4596.
    • (2014) BMJ , vol.349 , pp. g4596
    • Sattar, N.1
  • 42
    • 84919464333 scopus 로고    scopus 로고
    • Increasing prevalence of diabetes mellitus in association with fatty liver in a Japanese population
    • Imamura Y, Uto H, Hiramine Y, et al. (2014) Increasing prevalence of diabetes mellitus in association with fatty liver in a Japanese population. J Gastroenterol 49, 1406-1413.
    • (2014) J Gastroenterol , vol.49 , pp. 1406-1413
    • Imamura, Y.1    Uto, H.2    Hiramine, Y.3
  • 43
    • 36048934639 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-Aged Japanese men
    • Shibata M, Kihara Y, Taguchi M, et al. (2007) Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-Aged Japanese men. Diabetes Care 30, 2940-2944.
    • (2007) Diabetes Care , vol.30 , pp. 2940-2944
    • Shibata, M.1    Kihara, Y.2    Taguchi, M.3
  • 44
    • 84949457218 scopus 로고    scopus 로고
    • Identification of reciprocal causality between non-Alcoholic fatty liver disease and metabolic syndrome by a simplified Bayesian network in a Chinese population
    • Zhang Y, Zhang T, Zhang C, et al. (2015) Identification of reciprocal causality between non-Alcoholic fatty liver disease and metabolic syndrome by a simplified Bayesian network in a Chinese population. BMJ 5, e008204.
    • (2015) BMJ , vol.5 , pp. e008204
    • Zhang, Y.1    Zhang, T.2    Zhang, C.3
  • 45
    • 84879842291 scopus 로고    scopus 로고
    • The Netherlands Epidemiology of Obesity (NEO) study: Study design and data collection
    • De Mutsert R, Den Heijer M, Rabelink TJ, et al. (2013) The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection. Eur J Epidemiol 28, 513-523.
    • (2013) Eur J Epidemiol , vol.28 , pp. 513-523
    • De Mutsert, R.1    Den Heijer, M.2    Rabelink, T.J.3
  • 46
    • 84892881288 scopus 로고    scopus 로고
    • Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
    • Sumida Y, Nakajima A & Itoh Y (2014) Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 20, 475-485.
    • (2014) World J Gastroenterol , vol.20 , pp. 475-485
    • Sumida, Y.1    Nakajima, A.2    Itoh, Y.3
  • 47
    • 84861458280 scopus 로고    scopus 로고
    • Prediction for steatosis in type-2 diabetes: Clinico-biological markers versus 1H-MR spectroscopy
    • Guiu B, Crevisy-Girod E, Binquet C, et al. (2012) Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy. Eur Radiol 22, 855-863.
    • (2012) Eur Radiol , vol.22 , pp. 855-863
    • Guiu, B.1    Crevisy-Girod, E.2    Binquet, C.3
  • 48
    • 56649112801 scopus 로고    scopus 로고
    • Diagnosis of nonalcoholic fatty liver disease: Invasive versus noninvasive
    • Wieckowska A & Feldstein AE (2008) Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive. Semin Liver Dis 28, 386-395.
    • (2008) Semin Liver Dis , vol.28 , pp. 386-395
    • Wieckowska, A.1    Feldstein, A.E.2
  • 49
    • 84876293750 scopus 로고    scopus 로고
    • Non-invasive diagnosis of non-Alcoholic fatty liver disease. A critical appraisal
    • Machado MV & Cortez-Pinto H (2013) Non-invasive diagnosis of non-Alcoholic fatty liver disease. A critical appraisal. J Hepatol 58, 1007-1019.
    • (2013) J Hepatol , vol.58 , pp. 1007-1019
    • Machado, M.V.1    Cortez-Pinto, H.2
  • 50
    • 40449095940 scopus 로고    scopus 로고
    • Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point Dixon and three-point IDEAL
    • Kim H, Taksali SE, Dufour S, et al. (2008) Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point Dixon and three-point IDEAL. Magn Reson Med 59, 521-527.
    • (2008) Magn Reson Med , vol.59 , pp. 521-527
    • Kim, H.1    Taksali, S.E.2    Dufour, S.3
  • 51
    • 77951949746 scopus 로고    scopus 로고
    • MRI-determined fat content of human liver, pancreas and kidney
    • Sijens PE, Edens MA, Bakker SJL, et al. (2010) MRI-determined fat content of human liver, pancreas and kidney. World J Gastroenterol 16, 1993-1998.
    • (2010) World J Gastroenterol , vol.16 , pp. 1993-1998
    • Sijens, P.E.1    Edens, M.A.2    Bakker, S.J.L.3
  • 52
    • 84879979114 scopus 로고    scopus 로고
    • Improved hepatic lipid composition following short-Term exercise in nonalcoholic fatty liver disease
    • Haus JM, Solomon TPJ, Kelly KR, et al. (2013) Improved hepatic lipid composition following short-Term exercise in nonalcoholic fatty liver disease. J Clin Endocrinol Metab 98, E1181-E1188.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. E1181-E1188
    • Haus, J.M.1    Solomon, T.P.J.2    Kelly, K.R.3
  • 53
    • 85055597575 scopus 로고    scopus 로고
    • Quantum coherence spectroscopy to measure dietary fat retention in the liver
    • Lindeboom L, de Graaf RA, Nabuurs CI, et al. (2016) Quantum coherence spectroscopy to measure dietary fat retention in the liver. JCI Insight 1, e84671.
    • (2016) JCI Insight , vol.1 , pp. e84671
    • Lindeboom, L.1    De Graaf, R.A.2    Nabuurs, C.I.3
  • 54
    • 4143088340 scopus 로고    scopus 로고
    • Non-esterified fatty acids impair insulin-mediated glucose uptake and disposition in the liver
    • Iozzo P, Lautamaki R, Geisler F, et al. (2004) Non-esterified fatty acids impair insulin-mediated glucose uptake and disposition in the liver. Diabetologia 47, 1149-1156.
    • (2004) Diabetologia , vol.47 , pp. 1149-1156
    • Iozzo, P.1    Lautamaki, R.2    Geisler, F.3
  • 55
    • 84868008035 scopus 로고    scopus 로고
    • Increased myocardial uptake of dietary fatty acids linked to cardiac dysfunction in glucose-intolerant humans
    • Labbe SM, Grenier-Larouche T, Noll C, et al. (2012) Increased myocardial uptake of dietary fatty acids linked to cardiac dysfunction in glucose-intolerant humans. Diabetes 61, 2701-2710.
    • (2012) Diabetes , vol.61 , pp. 2701-2710
    • Labbe, S.M.1    Grenier-Larouche, T.2    Noll, C.3
  • 56
    • 34547514221 scopus 로고    scopus 로고
    • Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
    • Gastaldelli A, Cusi K, Pettiti M, et al. (2007) Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology 133, 496-506.
    • (2007) Gastroenterology , vol.133 , pp. 496-506
    • Gastaldelli, A.1    Cusi, K.2    Pettiti, M.3
  • 57
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
    • Korenblat KM, Fabbrini E, Mohammed BS, et al. (2008) Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 134, 1369-1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3
  • 58
    • 46049089412 scopus 로고    scopus 로고
    • Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes
    • Kotronen A, Juurinen L, Tiikkainen M, et al. (2008) Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes. Gastroenterology 135, 122-130.
    • (2008) Gastroenterology , vol.135 , pp. 122-130
    • Kotronen, A.1    Juurinen, L.2    Tiikkainen, M.3
  • 60
    • 84905845347 scopus 로고    scopus 로고
    • Metabolically healthy obesity, presence or absence of fatty liver, and risk of type 2 diabetes in Japanese individuals: Toranomon hospital health management center study 20 (TOPICS 20)
    • Heianza Y, Arase Y, Tsuji H, et al. (2014) Metabolically healthy obesity, presence or absence of fatty liver, and risk of type 2 diabetes in Japanese individuals: Toranomon Hospital Health Management Center Study 20 (TOPICS 20). J Clin Endocrinol Metab 99, 2952-2960.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. 2952-2960
    • Heianza, Y.1    Arase, Y.2    Tsuji, H.3
  • 61
    • 79951661646 scopus 로고    scopus 로고
    • Disposition index, glucose effectiveness, and conversion to type 2 diabetes: The Insulin Resistance Atherosclerosis Study (IRAS)
    • Lorenzo C, Wagenknecht LE, Rewers MJ, et al. (2010) Disposition index, glucose effectiveness, and conversion to type 2 diabetes: The Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care 33, 2098-2103.
    • (2010) Diabetes Care , vol.33 , pp. 2098-2103
    • Lorenzo, C.1    Wagenknecht, L.E.2    Rewers, M.J.3
  • 62
    • 77956151046 scopus 로고    scopus 로고
    • Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals
    • Iozzo P, Bucci M, Roivainen A, et al. (2010) Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals. Gastroenterology 139, 846-856.
    • (2010) Gastroenterology , vol.139 , pp. 846-856
    • Iozzo, P.1    Bucci, M.2    Roivainen, A.3
  • 63
    • 84920627017 scopus 로고    scopus 로고
    • Influence of liver triglycerides on suppression of glucose production by insulin in men
    • Jin ES, Szuszkiewicz-Garcia M, Browning JD, et al. (2015) Influence of liver triglycerides on suppression of glucose production by insulin in men. J Clin Endocrinol Metab 100, 235-243.
    • (2015) J Clin Endocrinol Metab , vol.100 , pp. 235-243
    • Jin, E.S.1    Szuszkiewicz-Garcia, M.2    Browning, J.D.3
  • 64
    • 77953893410 scopus 로고    scopus 로고
    • Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia
    • Amaro A, Fabbrini E, Kars M, et al. (2010) Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology 139, 149-153.
    • (2010) Gastroenterology , vol.139 , pp. 149-153
    • Amaro, A.1    Fabbrini, E.2    Kars, M.3
  • 65
    • 84952043139 scopus 로고    scopus 로고
    • Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-Alcoholic fatty liver disease
    • Cuthbertson DJ, Shojaee-Moradie F, Sprung VS, et al. (2016) Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-Alcoholic fatty liver disease. Clin Sci 130, 93-104.
    • (2016) Clin Sci , vol.130 , pp. 93-104
    • Cuthbertson, D.J.1    Shojaee-Moradie, F.2    Sprung, V.S.3
  • 66
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
    • Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. (2001) Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities. Gastroenterology 120, 1183-1192.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3
  • 67
    • 79951600838 scopus 로고    scopus 로고
    • Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease
    • Gentile CL, Frye MA & Pagliassotti MJ (2011) Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease. BioFactors 37, 8-16.
    • (2011) BioFactors , vol.37 , pp. 8-16
    • Gentile, C.L.1    Frye, M.A.2    Pagliassotti, M.J.3
  • 68
    • 84887568463 scopus 로고    scopus 로고
    • Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP
    • Xu X, So JS, Park JG, et al. (2013) Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP. Semin Liver Dis 33, 301-311.
    • (2013) Semin Liver Dis , vol.33 , pp. 301-311
    • Xu, X.1    So, J.S.2    Park, J.G.3
  • 69
    • 33747428040 scopus 로고    scopus 로고
    • Dietary glycemic index and liver steatosis
    • Valtuena S, Pellegrini N, Ardigó D, et al. (2006) Dietary glycemic index and liver steatosis. Am J Clin Nutr 84, 136-142.
    • (2006) Am J Clin Nutr , vol.84 , pp. 136-142
    • Valtuena, S.1    Pellegrini, N.2    Ardigó, D.3
  • 70
    • 84922087366 scopus 로고    scopus 로고
    • Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice
    • Keyhani-Nejad F, Irmler M, Isken F, et al. (2014) Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice. Diabetologia 58, 374-383.
    • (2014) Diabetologia , vol.58 , pp. 374-383
    • Keyhani-Nejad, F.1    Irmler, M.2    Isken, F.3
  • 71
    • 84942020260 scopus 로고    scopus 로고
    • Effects of insulin glargine and liraglutide therapy on liver fat as measured by magnetic resonance in patients with type 2 diabetes: A randomized trial
    • Tang A, Rabasa-Lhoret R, Castel H, et al. (2015) Effects of insulin glargine and liraglutide therapy on liver fat as measured by magnetic resonance in patients with type 2 diabetes: A randomized trial. Diabetes Care 38, 1339-1346.
    • (2015) Diabetes Care , vol.38 , pp. 1339-1346
    • Tang, A.1    Rabasa-Lhoret, R.2    Castel, H.3
  • 72
    • 77952545900 scopus 로고    scopus 로고
    • Combination of acarbose and ezetimibe prevents non-Alcoholic fatty liver disease: A break of intestinal insulin resistance?
    • Rudovich NN, Weickert MO, Machann J, et al. (2010) Combination of acarbose and ezetimibe prevents non-Alcoholic fatty liver disease: A break of intestinal insulin resistance? J Hepatol 52, 952-953.
    • (2010) J Hepatol , vol.52 , pp. 952-953
    • Rudovich, N.N.1    Weickert, M.O.2    Machann, J.3
  • 73
    • 74949110505 scopus 로고    scopus 로고
    • Impairment of fat oxidation under high- vs. Low-glycemic index diet occurs before the development of an obese phenotype
    • Isken F, Klaus S, Petzke KJ, et al. (2010) Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype. Am J Physiol Endocrinol Metab 298, E287-E295.
    • (2010) Am J Physiol Endocrinol Metab , vol.298 , pp. E287-E295
    • Isken, F.1    Klaus, S.2    Petzke, K.J.3
  • 74
    • 79955457155 scopus 로고    scopus 로고
    • Short-Term weight loss and hepatic triglyceride reduction: Evidence of a metabolic advantage with dietary carbohydrate restriction
    • Browning JD, Baker JA, Rogers T, et al. (2011) Short-Term weight loss and hepatic triglyceride reduction: Evidence of a metabolic advantage with dietary carbohydrate restriction. Am J Clin Nutr 93, 1048-1052.
    • (2011) Am J Clin Nutr , vol.93 , pp. 1048-1052
    • Browning, J.D.1    Baker, J.A.2    Rogers, T.3
  • 75
    • 84923845891 scopus 로고    scopus 로고
    • Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men
    • Kruse M, von Loeffelholz C, Hoffmann D, et al. (2015) Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men. Mol Nutr Food Res 59, 507-519.
    • (2015) Mol Nutr Food Res , vol.59 , pp. 507-519
    • Kruse, M.1    Von Loeffelholz, C.2    Hoffmann, D.3
  • 76
    • 84925485535 scopus 로고    scopus 로고
    • Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: A randomised feasibility trial
    • Nowotny B, Zahiragic L, Bierwagen A, et al. (2014) Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: A randomised feasibility trial. Diabetologia 58, 255-264.
    • (2014) Diabetologia , vol.58 , pp. 255-264
    • Nowotny, B.1    Zahiragic, L.2    Bierwagen, A.3
  • 77
    • 84930656108 scopus 로고    scopus 로고
    • NAFLD: A multisystem disease
    • Byrne CD & Targher G (2015) NAFLD: A multisystem disease. J Hepatol 62, S47-S64.
    • (2015) J Hepatol , vol.62 , pp. S47-S64
    • Byrne, C.D.1    Targher, G.2
  • 78
    • 84862075971 scopus 로고    scopus 로고
    • Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes
    • Sung K-C, Jeong W-S, Wild SH, et al. (2012) Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes. Diabetes Care 35, 717-722.
    • (2012) Diabetes Care , vol.35 , pp. 717-722
    • Sung, K.-C.1    Jeong, W.-S.2    Wild, S.H.3
  • 79
    • 84883686923 scopus 로고    scopus 로고
    • Resolution of fatty liver and risk of incident diabetes
    • Sung K-C, Wild SH & Byrne CD(2013) Resolution of fatty liver and risk of incident diabetes. J Clin Endocrinol Metab 98, 3637-3643.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 3637-3643
    • Sung, K.-C.1    Wild, S.H.2    Byrne, C.D.3
  • 80
    • 84884508163 scopus 로고    scopus 로고
    • A systematic review: Burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care?
    • Oni ET, Agatston AS, Blaha MJ, et al. (2013) A systematic review: burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care? Atherosclerosis 230, 258-267.
    • (2013) Atherosclerosis , vol.230 , pp. 258-267
    • Oni, E.T.1    Agatston, A.S.2    Blaha, M.J.3
  • 81
    • 84861329163 scopus 로고    scopus 로고
    • Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population
    • Stepanova M & Younossi ZM (2012) Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population. Clin Gastroenterol Hepatol 10, 646-650.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 646-650
    • Stepanova, M.1    Younossi, Z.M.2
  • 82
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • Targher G, Bertolini L, Padovani R, et al. (2007) Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care 30, 1212-1218.
    • (2007) Diabetes Care , vol.30 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 83
    • 84861417701 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease: A new and important cardiovascular risk factor?
    • Bhatia LS, Curzen NP, Calder PC, et al. (2012) Non-Alcoholic fatty liver disease: A new and important cardiovascular risk factor? Eur Heart J 33, 1190-1200.
    • (2012) Eur Heart J , vol.33 , pp. 1190-1200
    • Bhatia, L.S.1    Curzen, N.P.2    Calder, P.C.3
  • 84
    • 84942874843 scopus 로고    scopus 로고
    • Heart valve calcification in patients with type 2 diabetes and nonalcoholic fatty liver disease
    • Mantovani A, Pernigo M, Bergamini C, et al. (2015) Heart valve calcification in patients with type 2 diabetes and nonalcoholic fatty liver disease. Metabolism 64, 879-887.
    • (2015) Metabolism , vol.64 , pp. 879-887
    • Mantovani, A.1    Pernigo, M.2    Bergamini, C.3
  • 85
    • 84874317741 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes
    • Targher G, Valbusa F, Bonapace S, et al. (2013) Non-Alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes. PLOS ONE 8, e57183.
    • (2013) PLOS ONE , vol.8 , pp. e57183
    • Targher, G.1    Valbusa, F.2    Bonapace, S.3
  • 86
    • 84898816572 scopus 로고    scopus 로고
    • Development of new fatty liver, or resolution of existing fatty liver, over five years of follow-up, and risk of incident hypertension
    • Sung K-C, Wild SH & Byrne CD (2014) Development of new fatty liver, or resolution of existing fatty liver, over five years of follow-up, and risk of incident hypertension. J Hepatol 60, 1040-1045.
    • (2014) J Hepatol , vol.60 , pp. 1040-1045
    • Sung, K.-C.1    Wild, S.H.2    Byrne, C.D.3
  • 87
    • 84958172248 scopus 로고    scopus 로고
    • Omega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD
    • Nobili V, Alisi A, Musso G, et al. (2016) Omega-3 fatty acids: mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD. Crit Rev Clin Lab Sci 53, 106-120.
    • (2016) Crit Rev Clin Lab Sci , vol.53 , pp. 106-120
    • Nobili, V.1    Alisi, A.2    Musso, G.3
  • 88
    • 84904661185 scopus 로고    scopus 로고
    • No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial
    • Sanyal AJ, Abdelmalek MF, Suzuki A, et al. (2014) No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial. Gastroenterology 147, 377-384.
    • (2014) Gastroenterology , vol.147 , pp. 377-384
    • Sanyal, A.J.1    Abdelmalek, M.F.2    Suzuki, A.3
  • 89
    • 84927776586 scopus 로고    scopus 로고
    • Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the WELCOME study
    • Scorletti E, Bhatia L, McCormick KG, et al. (2014) Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the WELCOME study. Hepatology 60, 1211-1221.
    • (2014) Hepatology , vol.60 , pp. 1211-1221
    • Scorletti, E.1    Bhatia, L.2    McCormick, K.G.3
  • 90
    • 84945321040 scopus 로고    scopus 로고
    • Genetics of nonalcoholic fatty liver disease
    • Dongiovanni P & Valenti L (2016) Genetics of nonalcoholic fatty liver disease. Metabolism 65, 1026-1037.
    • (2016) Metabolism , vol.65 , pp. 1026-1037
    • Dongiovanni, P.1    Valenti, L.2
  • 91
    • 84885970553 scopus 로고    scopus 로고
    • The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-Alcoholic fatty liver disease
    • Nobili V, Bedogni G, Donati B, et al. (2013) The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-Alcoholic fatty liver disease. J Med Food 16, 957-960.
    • (2013) J Med Food , vol.16 , pp. 957-960
    • Nobili, V.1    Bedogni, G.2    Donati, B.3
  • 92
    • 84951567812 scopus 로고    scopus 로고
    • Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial
    • Scorletti E, West AL, Bhatia L, et al. (2015) Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial. J Hepatol 63, 1476-1483.
    • (2015) J Hepatol , vol.63 , pp. 1476-1483
    • Scorletti, E.1    West, A.L.2    Bhatia, L.3
  • 93
    • 84890569059 scopus 로고    scopus 로고
    • Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease
    • Banerjee R, Pavlides M, Tunnicliffe EM, et al. (2014)Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease. J Hepatol 60, 69-77.
    • (2014) J Hepatol , vol.60 , pp. 69-77
    • Banerjee, R.1    Pavlides, M.2    Tunnicliffe, E.M.3
  • 94
    • 84954365829 scopus 로고    scopus 로고
    • Multiparametric magnetic resonance imaging predicts clinical outcomes in patients with chronic liver disease
    • Pavlides M, Banerjee R, Sellwood J, et al. (2016) Multiparametric magnetic resonance imaging predicts clinical outcomes in patients with chronic liver disease. J Hepatol 64, 308-315.
    • (2016) J Hepatol , vol.64 , pp. 308-315
    • Pavlides, M.1    Banerjee, R.2    Sellwood, J.3
  • 95
    • 84952690391 scopus 로고    scopus 로고
    • Time to replace assessment of liver histology with MR-based imaging tests to assess efficacy of interventions for nonalcoholic fatty liver disease
    • Byrne CD & Targher G (2016) Time to replace assessment of liver histology with MR-based imaging tests to assess efficacy of interventions for nonalcoholic fatty liver disease. Gastroenterology 150, 7-10.
    • (2016) Gastroenterology , vol.150 , pp. 7-10
    • Byrne, C.D.1    Targher, G.2
  • 96
    • 34547726814 scopus 로고    scopus 로고
    • Brief report: Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects
    • Sato F, Tamura Y, Watada H, et al. (2007) Brief report: Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects. J Clin Endocrinol Metab 92, 3326-3329.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3326-3329
    • Sato, F.1    Tamura, Y.2    Watada, H.3
  • 97
    • 58149385620 scopus 로고    scopus 로고
    • Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance
    • Viljanen APM, Iozzo P, Borra R, et al. (2009) Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance. J Clin Endocrinol Metab 94, 50-55.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 50-55
    • Viljanen, A.P.M.1    Iozzo, P.2    Borra, R.3
  • 98
    • 70349785437 scopus 로고    scopus 로고
    • High protein intake reduces intrahepatocellular lipid deposition in humans
    • Bortolotti M, Kreis R, Debard C, et al. (2009) High protein intake reduces intrahepatocellular lipid deposition in humans. Am J Clin Nutr 90, 1002-1010.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1002-1010
    • Bortolotti, M.1    Kreis, R.2    Debard, C.3
  • 99
    • 47549099015 scopus 로고    scopus 로고
    • Effects of short-Term high-fat, high-energy diet on hepatic and myocardial triglyceride content in healthy men
    • Van Der Meer RW, Hammer S, Lamb HJ, et al. (2008) Effects of short-Term high-fat, high-energy diet on hepatic and myocardial triglyceride content in healthy men. J Clin Endocrinol Metab 93, 2702-2708.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2702-2708
    • Van Der Meer, R.W.1    Hammer, S.2    Lamb, H.J.3
  • 100
    • 65249179010 scopus 로고    scopus 로고
    • Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction
    • Kirk E, Reeds DN, Finck BN, et al. (2009) Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology 136, 1552-1560.
    • (2009) Gastroenterology , vol.136 , pp. 1552-1560
    • Kirk, E.1    Reeds, D.N.2    Finck, B.N.3
  • 101
    • 34247643885 scopus 로고    scopus 로고
    • Serum alanine aminotransferase levels decrease further with carbohydrate than fat restriction in insulin-resistant adults
    • Ryan MC, Abbasi F, Lamendola C, et al. (2007) Serum alanine aminotransferase levels decrease further with carbohydrate than fat restriction in insulin-resistant adults. Diabetes Care 30, 1075-1080.
    • (2007) Diabetes Care , vol.30 , pp. 1075-1080
    • Ryan, M.C.1    Abbasi, F.2    Lamendola, C.3
  • 102
    • 18844458833 scopus 로고    scopus 로고
    • Dietary fat content modifies liver fat in overweight nondiabetic subjects
    • Westerbacka J, Lammi K, Haekkinen A-M, et al. (2005) Dietary fat content modifies liver fat in overweight nondiabetic subjects. J Clin Endocrinol Metab 90, 2804-2809.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2804-2809
    • Westerbacka, J.1    Lammi, K.2    Haekkinen, A.-M.3
  • 103
    • 37849028864 scopus 로고    scopus 로고
    • Nutritional assessment and hepatic fatty acid composition in non-Alcoholic fatty liver disease (NAFLD): A cross-sectional study
    • Allard JP, Aghdassi E, Mohammed S, et al. (2008)Nutritional assessment and hepatic fatty acid composition in non-Alcoholic fatty liver disease (NAFLD): A cross-sectional study. J Hepatol 48, 300-307.
    • (2008) J Hepatol , vol.48 , pp. 300-307
    • Allard, J.P.1    Aghdassi, E.2    Mohammed, S.3
  • 104
    • 0037382071 scopus 로고    scopus 로고
    • Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
    • Musso G, Gambino R, De Michieli F, et al. (2003) Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 37, 909-916.
    • (2003) Hepatology , vol.37 , pp. 909-916
    • Musso, G.1    Gambino, R.2    De Michieli, F.3
  • 105
    • 77649335848 scopus 로고    scopus 로고
    • Serumfatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men
    • PeterssonH, Arnlöv J, Zethelius B, et al. (2010) Serumfatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men. Diabetes Res Clin Pract 87, 379-384.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 379-384
    • Petersson, H.1    Arnlöv, J.2    Zethelius, B.3
  • 106
    • 84863087186 scopus 로고    scopus 로고
    • Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes
    • Petit JM, Guiu B, Duvillard L, et al. (2012) Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes. Clin Nutr 31, 520-525.
    • (2012) Clin Nutr , vol.31 , pp. 520-525
    • Petit, J.M.1    Guiu, B.2    Duvillard, L.3
  • 107
    • 57649195613 scopus 로고    scopus 로고
    • Dietary fats and prevention of type 2 diabetes
    • Risérus U, Willett WC & Hu FB (2009) Dietary fats and prevention of type 2 diabetes. Prog Lipid Res 48, 44-51.
    • (2009) Prog Lipid Res , vol.48 , pp. 44-51
    • Risérus, U.1    Willett, W.C.2    Hu, F.B.3
  • 108
    • 84869213871 scopus 로고    scopus 로고
    • Phenotyping the effect of diet on non-Alcoholic fatty liver disease
    • De Wit NJW, Afman LA, Mensink M, et al. (2012) Phenotyping the effect of diet on non-Alcoholic fatty liver disease. J Hepatol 57, 1370-1373.
    • (2012) J Hepatol , vol.57 , pp. 1370-1373
    • De Wit, N.J.W.1    Afman, L.A.2    Mensink, M.3
  • 109
    • 0033806851 scopus 로고    scopus 로고
    • Differential oxidation of individual dietary fatty acids in humans
    • DeLany JP, Windhauser MM, Champagne CM, et al. (2000) Differential oxidation of individual dietary fatty acids in humans. Am J Clin Nutr 72, 905-911.
    • (2000) Am J Clin Nutr , vol.72 , pp. 905-911
    • DeLany, J.P.1    Windhauser, M.M.2    Champagne, C.M.3
  • 110
    • 84858703583 scopus 로고    scopus 로고
    • Omega-3 supplementation and non-Alcoholic fatty liver disease: A systematic review and meta-Analysis
    • Parker HM, Johnson NA, Burdon CA, et al. (2012) Omega-3 supplementation and non-Alcoholic fatty liver disease: A systematic review and meta-Analysis. J Hepatol 56, 944-951.
    • (2012) J Hepatol , vol.56 , pp. 944-951
    • Parker, H.M.1    Johnson, N.A.2    Burdon, C.A.3
  • 111
    • 84918554640 scopus 로고    scopus 로고
    • Effects of n-3 fish oil on metabolic and histological parameters in NASH: A doubleblind, randomized, placebo-controlled trial
    • Argo CK, Patrie JT, Lackner C, et al. (2015) Effects of n-3 fish oil on metabolic and histological parameters in NASH: A doubleblind, randomized, placebo-controlled trial. J Hepatol 62, 190-197.
    • (2015) J Hepatol , vol.62 , pp. 190-197
    • Argo, C.K.1    Patrie, J.T.2    Lackner, C.3
  • 112
    • 84952988188 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Roles of the gut and the liver and metabolic modulation by some dietary factors and especially long-chain n-3 PUFA
    • Delarue J & Lallès J-P (2016) Nonalcoholic fatty liver disease: Roles of the gut and the liver and metabolic modulation by some dietary factors and especially long-chain n-3 PUFA. Mol Nutr Food Res 60, 147-159.
    • (2016) Mol Nutr Food Res , vol.60 , pp. 147-159
    • Delarue, J.1    Lallès, J.-P.2
  • 113
    • 84866621997 scopus 로고    scopus 로고
    • Effect of short-Term carbohydrate overfeeding and long-Term weight loss on liver fat in overweight humans
    • Sevastianova K, Santos A, Kotronen A, et al. (2012) Effect of short-Term carbohydrate overfeeding and long-Term weight loss on liver fat in overweight humans. Am J Clin Nutr 96, 727-734.
    • (2012) Am J Clin Nutr , vol.96 , pp. 727-734
    • Sevastianova, K.1    Santos, A.2    Kotronen, A.3
  • 114
    • 84878276815 scopus 로고    scopus 로고
    • Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans
    • Lecoultre V, Egli L, Carrel G, et al. (2013) Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans. Obesity 21, 782-785.
    • (2013) Obesity , vol.21 , pp. 782-785
    • Lecoultre, V.1    Egli, L.2    Carrel, G.3
  • 115
    • 84856376705 scopus 로고    scopus 로고
    • Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: A 6-mo randomized intervention study
    • Maersk M, Belza A, Stoedkilde-Joergensen H, et al. (2012) Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: A 6-mo randomized intervention study. Am J Clin Nutr 95, 283-289.
    • (2012) Am J Clin Nutr , vol.95 , pp. 283-289
    • Maersk, M.1    Belza, A.2    Stoedkilde-Joergensen, H.3
  • 116
    • 84943163394 scopus 로고    scopus 로고
    • Similar reduction of cholesterol-Adjusted Vitamin E serum levels in simple steatosis and non-Alcoholic steatohepatitis
    • Pastori D, Baratta F, Carnevale R, et al. (2015) Similar reduction of cholesterol-Adjusted vitamin E serum levels in simple steatosis and non-Alcoholic steatohepatitis. Clin Trans Gastroenterol 6, e113.
    • (2015) Clin Trans Gastroenterol , vol.6 , pp. e113
    • Pastori, D.1    Baratta, F.2    Carnevale, R.3
  • 117
    • 84939938313 scopus 로고    scopus 로고
    • Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
    • Watanabe S, Hashimoto E, Ikejima K, et al. (2015) Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. J Gastroenterol 50, 364-377.
    • (2015) J Gastroenterol , vol.50 , pp. 364-377
    • Watanabe, S.1    Hashimoto, E.2    Ikejima, K.3
  • 118
    • 84883259255 scopus 로고    scopus 로고
    • Vitamin D and nonalcoholic fatty liver disease (NAFLD): Is it more than just an association?
    • Kwok RM, Torres DM & Harrison SA (2013) Vitamin D and nonalcoholic fatty liver disease (NAFLD): is it more than just an association? Hepatology 58, 1166-1174.
    • (2013) Hepatology , vol.58 , pp. 1166-1174
    • Kwok, R.M.1    Torres, D.M.2    Harrison, S.A.3
  • 119
    • 84918791665 scopus 로고    scopus 로고
    • Resveratrol does not benefit patients with nonalcoholic fatty liver disease
    • Chachay VS, Macdonald GA, Martin JH, et al. (2014) Resveratrol does not benefit patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 12, 2092-2103.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 2092-2103
    • Chachay, V.S.1    Macdonald, G.A.2    Martin, J.H.3
  • 120
    • 78149284427 scopus 로고    scopus 로고
    • Nutritional modulation of nonalcoholic fatty liver disease and insulin resistance: Human data
    • Yki-Järvinen H (2010) Nutritional modulation of nonalcoholic fatty liver disease and insulin resistance: human data. Curr Opin Clin Nutr Metab Care 13, 709-714.
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 709-714
    • Yki-Järvinen, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.