메뉴 건너뛰기




Volumn 20, Issue 2, 2014, Pages 475-485

Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Author keywords

Fibrosis; Liver biopsy; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Steatosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA 2 MACROGLOBULIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; COLLAGEN TYPE 4; CYTOKERATIN; CYTOKERATIN 18; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; TRIACYLGLYCEROL; BIOLOGICAL MARKER;

EID: 84892881288     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i2.475     Document Type: Review
Times cited : (484)

References (79)
  • 1
    • 84865126374 scopus 로고    scopus 로고
    • Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: A multicenter large retrospective study
    • [PMID: 22328022 DOI: 10.1007/s00535-012-0533-z]
    • Eguchi Y, Hyogo H, Ono M, Mizuta T, Ono N, Fujimoto K, Chayama K, Saibara T. Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study. J Gastroenterol 2012; 47: 586-595 [PMID: 22328022 DOI: 10.1007/s00535-012-0533-z]
    • (2012) J Gastroenterol , vol.47 , pp. 586-595
    • Eguchi, Y.1    Hyogo, H.2    Ono, M.3    Mizuta, T.4    Ono, N.5    Fujimoto, K.6    Chayama, K.7    Saibara, T.8
  • 2
    • 80555136061 scopus 로고    scopus 로고
    • Metaanalysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • [PMID: 21039302 DOI: 10.3109/07853890.2010.518623]
    • Musso G, Gambino R, Cassader M, Pagano G. Metaanalysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 2011; 43: 617-649 [PMID: 21039302 DOI: 10.3109/07853890.2010.518623]
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 3
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • [PMID: 22488764 DOI: 10.1002/hep.25762]
    • Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M, Sanyal AJ. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012; 55: 2005-2023 [PMID: 22488764 DOI: 10.1002/hep.25762]
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6    Charlton, M.7    Sanyal, A.J.8
  • 4
    • 80052012241 scopus 로고    scopus 로고
    • Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: A meta-analysis
    • [PMID: 21618575 DOI: 10.1002/hep.24452]
    • Hernaez R, Lazo M, Bonekamp S, Kamel I, Brancati FL, Guallar E, Clark JM. Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis. Hepatology 2011; 54: 1082-1090 [PMID: 21618575 DOI: 10.1002/hep.24452]
    • (2011) Hepatology , vol.54 , pp. 1082-1090
    • Hernaez, R.1    Lazo, M.2    Bonekamp, S.3    Kamel, I.4    Brancati, F.L.5    Guallar, E.6    Clark, J.M.7
  • 5
    • 71849092184 scopus 로고    scopus 로고
    • Validity of real time ultrasound in the diagnosis of hepatic steatosis: A prospective study
    • [PMID: 19846234 DOI: 10.1016/ j.jhep.2009.09.001]
    • Dasarathy S, Dasarathy J, Khiyami A, Joseph R, Lopez R, McCullough AJ. Validity of real time ultrasound in the diagnosis of hepatic steatosis: a prospective study. J Hepatol 2009; 51: 1061-1067 [PMID: 19846234 DOI: 10.1016/ j.jhep.2009.09.001]
    • (2009) J Hepatol , vol.51 , pp. 1061-1067
    • Dasarathy, S.1    Dasarathy, J.2    Khiyami, A.3    Joseph, R.4    Lopez, R.5    McCullough, A.J.6
  • 7
    • 50849125424 scopus 로고    scopus 로고
    • Imaging techniques for assessing hepatic fat content in nonalcoholic fatty liver disease
    • [PMID: 18753987]
    • Roldan-Valadez E, Favila R, Martínez-López M, Uribe M, Méndez-Sánchez N. Imaging techniques for assessing hepatic fat content in nonalcoholic fatty liver disease. Ann Hepatol 2008; 7: 212-220 [PMID: 18753987]
    • (2008) Ann Hepatol , vol.7 , pp. 212-220
    • Roldan-Valadez, E.1    Favila, R.2    Martínez-López, M.3    Uribe, M.4    Méndez-Sánchez, N.5
  • 9
    • 0034862590 scopus 로고    scopus 로고
    • Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology
    • [PMID: 11580141]
    • Skelly MM, James PD, Ryder SD. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol 2001; 35: 195-199 [PMID: 11580141]
    • (2001) J Hepatol , vol.35 , pp. 195-199
    • Skelly, M.M.1    James, P.D.2    Ryder, S.D.3
  • 10
    • 0032822946 scopus 로고    scopus 로고
    • Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients
    • [PMID: 10520861]
    • Daniel S, Ben-Menachem T, Vasudevan G, Ma CK, Blumenkehl M. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 1999; 94: 3010-3014 [PMID: 10520861]
    • (1999) Am J Gastroenterol , vol.94 , pp. 3010-3014
    • Daniel, S.1    Ben-Menachem, T.2    Vasudevan, G.3    Ma, C.K.4    Blumenkehl, M.5
  • 12
    • 33645786275 scopus 로고    scopus 로고
    • Hepatic lipid accumulation in healthy subjects: A comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy
    • [PMID: 16506186]
    • Machann J, Thamer C, Schnoedt B, Stefan N, Haring HU, Claussen CD, Fritsche A, Schick F. Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy. Magn Reson Med 2006; 55: 913-917 [PMID: 16506186]
    • (2006) Magn Reson Med , vol.55 , pp. 913-917
    • McHann, J.1    Thamer, C.2    Schnoedt, B.3    Stefan, N.4    Haring, H.U.5    Claussen, C.D.6    Fritsche, A.7    Schick, F.8
  • 14
    • 84861981022 scopus 로고    scopus 로고
    • Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography
    • [PMID: 22672642 DOI: 10.1111/ j.1478-3231.2012.02820.x]
    • de Lédinghen V, Vergniol J, Foucher J, Merrouche W, le Bail B. Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography. Liver Int 2012; 32: 911-918 [PMID: 22672642 DOI: 10.1111/ j.1478-3231.2012.02820.x]
    • (2012) Liver Int , vol.32 , pp. 911-918
    • de Lédinghen, V.1    Vergniol, J.2    Foucher, J.3    Merrouche, W.4    le Bail, B.5
  • 17
    • 77955553316 scopus 로고    scopus 로고
    • Hepatic steatosis index: A simple screening tool reflecting nonalcoholic fatty liver disease
    • [PMID: 19766548 DOI: 10.1016/j.dld.2009.08.002]
    • Lee JH, Kim D, Kim HJ, Lee CH, Yang JI, Kim W, Kim YJ, Yoon JH, Cho SH, Sung MW, Lee HS. Hepatic steatosis index: a simple screening tool reflecting nonalcoholic fatty liver disease. Dig Liver Dis 2010; 42: 503-508 [PMID: 19766548 DOI: 10.1016/j.dld.2009.08.002]
    • (2010) Dig Liver Dis , vol.42 , pp. 503-508
    • Lee, J.H.1    Kim, D.2    Kim, H.J.3    Lee, C.H.4    Yang, J.I.5    Kim, W.6    Kim, Y.J.7    Yoon, J.H.8    Cho, S.H.9    Sung, M.W.10    Lee, H.S.11
  • 20
    • 0036812716 scopus 로고    scopus 로고
    • Motion-all patients with NASH need to have a liver biopsy: Arguments against the motion
    • [PMID: 12420035]
    • Laurin J. Motion-all patients with NASH need to have a liver biopsy: arguments against the motion. Can J Gastroenterol 2002; 16: 722-726 [PMID: 12420035]
    • (2002) Can J Gastroenterol , vol.16 , pp. 722-726
    • Laurin, J.1
  • 21
    • 14644444565 scopus 로고    scopus 로고
    • Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens
    • [PMID: 15716234]
    • Goldstein NS, Hastah F, Galan MV, Gordon SC. Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens. Am J Clin Pathol 2005; 123: 382-387 [PMID: 15716234]
    • (2005) Am J Clin Pathol , vol.123 , pp. 382-387
    • Goldstein, N.S.1    Hastah, F.2    Galan, M.V.3    Gordon, S.C.4
  • 22
    • 62849123229 scopus 로고    scopus 로고
    • Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic Fatty liver disease
    • [PMID: 19162235 DOI: 10.1016/j.cgh.2008.12.015]
    • Vuppalanchi R, Unalp A, Van Natta ML, Cummings OW, Sandrasegaran KE, Hameed T, Tonascia J, Chalasani N. Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic Fatty liver disease. Clin Gastroenterol Hepatol 2009; 7: 481-486 [PMID: 19162235 DOI: 10.1016/j.cgh.2008.12.015]
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 481-486
    • Vuppalanchi, R.1    Unalp, A.2    Van Natta, M.L.3    Cummings, O.W.4    Sandrasegaran, K.E.5    Hameed, T.6    Tonascia, J.7    Chalasani, N.8
  • 23
    • 35548959472 scopus 로고    scopus 로고
    • Histopathologic variability between the right and left lobes of the liver in morbidly obese patients undergoing Roux-en-Y bypass
    • [PMID: 17702661]
    • Larson SP, Bowers SP, Palekar NA, Ward JA, Pulcini JP, Harrison SA. Histopathologic variability between the right and left lobes of the liver in morbidly obese patients undergoing Roux-en-Y bypass. Clin Gastroenterol Hepatol 2007; 5: 1329-1332 [PMID: 17702661]
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1329-1332
    • Larson, S.P.1    Bowers, S.P.2    Palekar, N.A.3    Ward, J.A.4    Pulcini, J.P.5    Harrison, S.A.6
  • 25
    • 18044373000 scopus 로고    scopus 로고
    • Histologic variation of grade and stage of non-alcoholic fatty liver disease in liver biopsies
    • [PMID: 15946428]
    • Janiec DJ, Jacobson ER, Freeth A, Spaulding L, Blaszyk H. Histologic variation of grade and stage of non-alcoholic fatty liver disease in liver biopsies. Obes Surg 2005; 15: 497-501 [PMID: 15946428]
    • (2005) Obes Surg , vol.15 , pp. 497-501
    • Janiec, D.J.1    Jacobson, E.R.2    Freeth, A.3    Spaulding, L.4    Blaszyk, H.5
  • 26
    • 33750617920 scopus 로고    scopus 로고
    • Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease
    • [PMID: 17006934]
    • Merriman RB, Ferrell LD, Patti MG, Weston SR, Pabst MS, Aouizerat BE, Bass NM. Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease. Hepatology 2006; 44: 874-880 [PMID: 17006934]
    • (2006) Hepatology , vol.44 , pp. 874-880
    • Merriman, R.B.1    Ferrell, L.D.2    Patti, M.G.3    Weston, S.R.4    Pabst, M.S.5    Aouizerat, B.E.6    Bass, N.M.7
  • 29
    • 78751575786 scopus 로고    scopus 로고
    • Effects of interventions on intra-and interobserver agreement on interpretation of nonalcoholic fatty liver disease histology
    • [PMID: 21106424 DOI: 10.1016/j.anndiagpath.2010.08.001]
    • Gawrieh S, Knoedler DM, Saeian K, Wallace JR, Komorowski RA. Effects of interventions on intra-and interobserver agreement on interpretation of nonalcoholic fatty liver disease histology. Ann Diagn Pathol 2011; 15: 19-24 [PMID: 21106424 DOI: 10.1016/j.anndiagpath.2010.08.001]
    • (2011) Ann Diagn Pathol , vol.15 , pp. 19-24
    • Gawrieh, S.1    Knoedler, D.M.2    Saeian, K.3    Wallace, J.R.4    Komorowski, R.A.5
  • 31
    • 33749872352 scopus 로고    scopus 로고
    • Twenty-year audit of percutaneous liver biopsy in a major Australian teaching hospital
    • [PMID: 17040353]
    • van der Poorten D, Kwok A, Lam T, Ridley L, Jones DB, Ngu MC, Lee AU. Twenty-year audit of percutaneous liver biopsy in a major Australian teaching hospital. Intern Med J 2006; 36: 692-699 [PMID: 17040353]
    • (2006) Intern Med J , vol.36 , pp. 692-699
    • van der Poorten, D.1    Kwok, A.2    Lam, T.3    Ridley, L.4    Jones, D.B.5    Ngu, M.C.6    Lee, A.U.7
  • 32
    • 0033849619 scopus 로고    scopus 로고
    • Practices of liver biopsy in France: Results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF)
    • [PMID: 10960438]
    • Cadranel JF, Rufat P, Degos F. Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF). Hepatology 2000; 32: 477-481 [PMID: 10960438]
    • (2000) Hepatology , vol.32 , pp. 477-481
    • Cadranel, J.F.1    Rufat, P.2    Degos, F.3
  • 34
    • 1442282964 scopus 로고    scopus 로고
    • Controversies in liver biopsy: Who, where, when, how, why?
    • [PMID: 14720451]
    • Friedman LS. Controversies in liver biopsy: who, where, when, how, why? Curr Gastroenterol Rep 2004; 6: 30-36 [PMID: 14720451]
    • (2004) Curr Gastroenterol Rep , vol.6 , pp. 30-36
    • Friedman, L.S.1
  • 38
    • 79959379215 scopus 로고    scopus 로고
    • Validation of the non-alcoholic fatty liver disease activity score
    • [PMID: 21585409 DOI: 10.1111/j.1365-2036.2011.04695.x]
    • Hjelkrem M, Stauch C, Shaw J, Harrison SA. Validation of the non-alcoholic fatty liver disease activity score. Aliment Pharmacol Ther 2011; 34: 214-218 [PMID: 21585409 DOI: 10.1111/j.1365-2036.2011.04695.x]
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 214-218
    • Hjelkrem, M.1    Stauch, C.2    Shaw, J.3    Harrison, S.A.4
  • 39
    • 78650953709 scopus 로고    scopus 로고
    • Generalizability of the nonalcoholic steatohepatitis Clinical Research Network histologic scoring system for nonalcoholic fatty liver disease
    • [PMID: 20505526 DOI: 10.1097/MCG.0b013e3181dd1348]
    • Juluri R, Vuppalanchi R, Olson J, Unalp A, Van Natta ML, Cummings OW, Tonascia J, Chalasani N. Generalizability of the nonalcoholic steatohepatitis Clinical Research Network histologic scoring system for nonalcoholic fatty liver disease. J Clin Gastroenterol 2011; 45: 55-58 [PMID: 20505526 DOI: 10.1097/MCG.0b013e3181dd1348]
    • (2011) J Clin Gastroenterol , vol.45 , pp. 55-58
    • Juluri, R.1    Vuppalanchi, R.2    Olson, J.3    Unalp, A.4    Van Natta, M.L.5    Cummings, O.W.6    Tonascia, J.7    Chalasani, N.8
  • 40
    • 79952231349 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: Distinct clinicopathologic meanings
    • [PMID: 21319198 DOI: 10.1002/hep.24127]
    • Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA. Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology 2011; 53: 810-820 [PMID: 21319198 DOI: 10.1002/hep.24127]
    • (2011) Hepatology , vol.53 , pp. 810-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3    Belt, P.4    Neuschwander-Tetri, B.A.5
  • 41
    • 79957521377 scopus 로고    scopus 로고
    • Pathologic criteria for nonalcoholic steatohepatitis: Interprotocol agreement and ability to predict liver-related mortality
    • [PMID: 21360720 DOI: 10.1002/hep.24268]
    • Younossi ZM, Stepanova M, Rafiq N, Makhlouf H, Younoszai Z, Agrawal R, Goodman Z. Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality. Hepatology 2011; 53: 1874-1882 [PMID: 21360720 DOI: 10.1002/hep.24268]
    • (2011) Hepatology , vol.53 , pp. 1874-1882
    • Younossi, Z.M.1    Stepanova, M.2    Rafiq, N.3    Makhlouf, H.4    Younoszai, Z.5    Agrawal, R.6    Goodman, Z.7
  • 42
    • 80052584666 scopus 로고    scopus 로고
    • Markedly lower follow-up rate after liver biopsy in patients with non-alcoholic fatty liver diseases than those with viral hepatitis in Japan
    • [PMID: 21906297 DOI: 10.1186/1756-0500-4-341]
    • Toyoda H, Kumada T, Kiriyama S, Tanikawa M, Hisanaga Y, Kanamori A, Tada T. Markedly lower follow-up rate after liver biopsy in patients with non-alcoholic fatty liver diseases than those with viral hepatitis in Japan. BMC Res Notes 2011; 4: 341 [PMID: 21906297 DOI: 10.1186/1756-0500-4-341]
    • (2011) BMC Res Notes , vol.4 , pp. 341
    • Toyoda, H.1    Kumada, T.2    Kiriyama, S.3    Tanikawa, M.4    Hisanaga, Y.5    Kanamori, A.6    Tada, T.7
  • 43
    • 84864107424 scopus 로고    scopus 로고
    • Can NASH be diagnosed, graded, and staged noninvasively?
    • [PMID: 22824481 DOI: 10.1016/j.cld.2012.05.001]
    • Grandison GA, Angulo P. Can NASH be diagnosed, graded, and staged noninvasively? Clin Liver Dis 2012; 16: 567-585 [PMID: 22824481 DOI: 10.1016/j.cld.2012.05.001]
    • (2012) Clin Liver Dis , vol.16 , pp. 567-585
    • Grandison, G.A.1    Angulo, P.2
  • 44
    • 78751476826 scopus 로고    scopus 로고
    • Noninvasive assessment of liver fibrosis
    • [PMID: 21254180 DOI: 10.1002/hep.24013]
    • Martínez SM, Crespo G, Navasa M, Forns X. Noninvasive assessment of liver fibrosis. Hepatology 2011; 53: 325-335 [PMID: 21254180 DOI: 10.1002/hep.24013]
    • (2011) Hepatology , vol.53 , pp. 325-335
    • Martínez, S.M.1    Crespo, G.2    Navasa, M.3    Forns, X.4
  • 45
    • 79951521515 scopus 로고    scopus 로고
    • Toward a biochemical diagnosis of NASH: Insights from pathophysiology for distinguishing simple steatosis from steatohepatitis
    • [PMID: 21182485]
    • Yilmaz Y, Ulukaya E. Toward a biochemical diagnosis of NASH: insights from pathophysiology for distinguishing simple steatosis from steatohepatitis. Curr Med Chem 2011; 18: 725-732 [PMID: 21182485]
    • (2011) Curr Med Chem , vol.18 , pp. 725-732
    • Yilmaz, Y.1    Ulukaya, E.2
  • 46
    • 79954455313 scopus 로고    scopus 로고
    • Current status and agenda in the diagnosis of nonalcoholic steatohepatitis in Japan
    • [PMID: 21160946 DOI: 10.4254/wjh. v2.i10.374]
    • Sumida Y, Eguchi Y, Ono M. Current status and agenda in the diagnosis of nonalcoholic steatohepatitis in Japan. World J Hepatol 2010; 2: 374-383 [PMID: 21160946 DOI: 10.4254/wjh. v2.i10.374]
    • (2010) World J Hepatol , vol.2 , pp. 374-383
    • Sumida, Y.1    Eguchi, Y.2    Ono, M.3
  • 47
    • 80053620109 scopus 로고    scopus 로고
    • Cytokeratins in hepatitis
    • [PMID: 21925155]
    • Yilmaz Y. Cytokeratins in hepatitis. Clin Chim Acta 2011; 412: 2031-2036 [PMID: 21925155]
    • (2011) Clin Chim Acta , vol.412 , pp. 2031-2036
    • Yilmaz, Y.1
  • 48
    • 84904742582 scopus 로고    scopus 로고
    • Serum cytokeratin-18 in the diagnosis of non-alcoholic steatohepatitis: A meta-analysis
    • Jul 9; Epub ahead of print [PMID: 23834322 DOI: 0.1111/hepr.12197]
    • Chen J, Zhu Y, Zheng Q, Jiang J. Serum cytokeratin-18 in the diagnosis of non-alcoholic steatohepatitis: A meta-analysis. Hepatol Res 2013 Jul 9; Epub ahead of print [PMID: 23834322 DOI: 0.1111/hepr.12197]
    • (2013) Hepatol Res
    • Chen, J.1    Zhu, Y.2    Zheng, Q.3    Jiang, J.4
  • 49
    • 0034950652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
    • [PMID: 11438497]
    • Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001; 121: 91-100 [PMID: 11438497]
    • (2001) Gastroenterology , vol.121 , pp. 91-100
    • Dixon, J.B.1    Bhathal, P.S.2    O'Brien, P.E.3
  • 50
    • 33646013904 scopus 로고    scopus 로고
    • Clinical model for distinguishing nonalcoholic steatohepatitis from simple steatosis in patients with nonalcoholic fatty liver disease
    • [PMID: 16448452]
    • Palekar NA, Naus R, Larson SP, Ward J, Harrison SA. Clinical model for distinguishing nonalcoholic steatohepatitis from simple steatosis in patients with nonalcoholic fatty liver disease. Liver Int 2006; 26: 151-156 [PMID: 16448452]
    • (2006) Liver Int , vol.26 , pp. 151-156
    • Palekar, N.A.1    Naus, R.2    Larson, S.P.3    Ward, J.4    Harrison, S.A.5
  • 55
    • 34547539428 scopus 로고    scopus 로고
    • Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis
    • [PMID: 17511754]
    • Shimada M, Kawahara H, Ozaki K, Fukura M, Yano H, Tsuchishima M, Tsutsumi M, Takase S. Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis. Am J Gastroenterol 2007; 102: 1931-1938 [PMID: 17511754]
    • (2007) Am J Gastroenterol , vol.102 , pp. 1931-1938
    • Shimada, M.1    Kawahara, H.2    Ozaki, K.3    Fukura, M.4    Yano, H.5    Tsuchishima, M.6    Tsutsumi, M.7    Takase, S.8
  • 60
    • 52649112178 scopus 로고    scopus 로고
    • Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease
    • [PMID: 18390575 DOI: 10.1136/gut.2007.146019]
    • Harrison SA, Oliver D, Arnold HL, Gogia S, Neuschwander-Tetri BA. Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease. Gut 2008; 57: 1441-1447 [PMID: 18390575 DOI: 10.1136/gut.2007.146019]
    • (2008) Gut , vol.57 , pp. 1441-1447
    • Harrison, S.A.1    Oliver, D.2    Arnold, H.L.3    Gogia, S.4    Neuschwander-Tetri, B.A.5
  • 61
    • 70350220466 scopus 로고    scopus 로고
    • Applicability of BARD score to Japanese patients with NAFLD
    • [PMID: 19834122 DOI: 10.1136/gut.2009.182758]. author reply 1567
    • Fujii H, Enomoto M, Fukushima W, Tamori A, Sakaguchi H, Kawada N. Applicability of BARD score to Japanese patients with NAFLD. Gut 2009; 58: 1566-1567; author reply 1567 [PMID: 19834122 DOI: 10.1136/gut.2009.182758]
    • (2009) Gut , vol.58 , pp. 1566-1567
    • Fujii, H.1    Enomoto, M.2    Fukushima, W.3    Tamori, A.4    Sakaguchi, H.5    Kawada, N.6
  • 62
    • 70349546276 scopus 로고    scopus 로고
    • Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease
    • [PMID: 19523535 DOI: 10.1016/j.cgh.2009.05.033]
    • Shah AG, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2009; 7: 1104-1112 [PMID: 19523535 DOI: 10.1016/j.cgh.2009.05.033]
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1104-1112
    • Shah, A.G.1    Lydecker, A.2    Murray, K.3    Tetri, B.N.4    Contos, M.J.5    Sanyal, A.J.6
  • 65
    • 79960140941 scopus 로고    scopus 로고
    • Usefulness of combination of platelet count and AST/ALT ratio (PAAR index) for excluding advanced fibrosis in nonalcoholic fatty liver disease
    • Available from: URL
    • Sumida Y, Ohno T, Sakai K, Kanemasa K, Imai S. Usefulness of combination of platelet count and AST/ALT ratio (PAAR index) for excluding advanced fibrosis in nonalcoholic fatty liver disease. Kanzo 2011; 52: 383-386. Available from: URL: https://www.jstage.jst.go.jp/article/kanzo/52/6/ 52_6_383/_pdf
    • (2011) Kanzo , vol.52 , pp. 383-386
    • Sumida, Y.1    Ohno, T.2    Sakai, K.3    Kanemasa, K.4    Imai, S.5
  • 66
    • 84877010489 scopus 로고    scopus 로고
    • Are simple noninvasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels?
    • [PMID: 23325287 DOI: 10.1097/MEG.0b013e32835d72cf]
    • McPherson S, Anstee QM, Henderson E, Day CP, Burt AD. Are simple noninvasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels? Eur J Gastroenterol Hepatol 2013; 25: 652-658 [PMID: 23325287 DOI: 10.1097/MEG.0b013e32835d72cf]
    • (2013) Eur J Gastroenterol Hepatol , vol.25 , pp. 652-658
    • McPherson, S.1    Anstee, Q.M.2    Henderson, E.3    Day, C.P.4    Burt, A.D.5
  • 69
    • 84876130551 scopus 로고    scopus 로고
    • Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States
    • [PMID: 23175136 DOI: 10.1002/hep.26156]
    • Kim D, Kim WR, Kim HJ, Therneau TM. Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States. Hepatology 2013; 57: 1357-1365 [PMID: 23175136 DOI: 10.1002/hep.26156]
    • (2013) Hepatology , vol.57 , pp. 1357-1365
    • Kim, D.1    Kim, W.R.2    Kim, H.J.3    Therneau, T.M.4
  • 70
    • 65149086682 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A practical approach to evaluation and management
    • [PMID: 19442917 DOI: 10.1016/ j.cld.2009.02.009]
    • Rafiq N, Younossi ZM. Nonalcoholic fatty liver disease: a practical approach to evaluation and management. Clin Liver Dis 2009; 13: 249-266 [PMID: 19442917 DOI: 10.1016/ j.cld.2009.02.009]
    • (2009) Clin Liver Dis , vol.13 , pp. 249-266
    • Rafiq, N.1    Younossi, Z.M.2
  • 72
    • 78650336759 scopus 로고    scopus 로고
    • Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease
    • [PMID: 21176169 DOI: 10.1186 /1471-2350-11-172]
    • Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. BMC Med Genet 2010; 11: 172 [PMID: 21176169 DOI: 10.1186 /1471-2350-11-172]
    • (2010) BMC Med Genet , vol.11 , pp. 172
    • Hotta, K.1    Yoneda, M.2    Hyogo, H.3    Ochi, H.4    Mizusawa, S.5    Ueno, T.6    Chayama, K.7    Nakajima, A.8    Nakao, K.9    Sekine, A.10
  • 74
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • [PMID: 20684021 DOI: 10.1002/hep.23759]
    • Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 2010; 52: 894-903 [PMID: 20684021 DOI: 10.1002/hep.23759]
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1    Koh, C.2    Zmuda, J.M.3    Kleiner, D.E.4    Liang, T.J.5
  • 76
    • 79957462315 scopus 로고    scopus 로고
    • Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
    • [PMID: 21381068 DOI: 10.1002/hep.24283]
    • Sookoian S, Pirola CJ. Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 2011; 53: 1883-1894 [PMID: 21381068 DOI: 10.1002/hep.24283]
    • (2011) Hepatology , vol.53 , pp. 1883-1894
    • Sookoian, S.1    Pirola, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.