메뉴 건너뛰기




Volumn 29, Issue 10, 2015, Pages 1414-1425

Liver perilipin 5 expression worsens hepatosteatosis but not insulin resistance in high fat-fed mice

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CHOLESTEROL ESTER; DIACYLGLYCEROL; INSULIN; PERILIPIN; PERILIPIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHOLIPID; PROTEIN KINASE B; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FAT DROPLET; GLUCOSE; LIPID STORAGE DROPLET PROTEIN 5, MOUSE; MUSCLE PROTEIN; SIGNAL PEPTIDE;

EID: 84943262988     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/me.2015-1069     Document Type: Article
Times cited : (38)

References (55)
  • 2
    • 83755178774 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and mortality among US adults: Prospective cohort study
    • Lazo M, Hernaez R, Bonekamp S, et al. Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study. BMJ. 2011;343:d6891.
    • (2011) BMJ , vol.343 , pp. d6891
    • Lazo, M.1    Hernaez, R.2    Bonekamp, S.3
  • 3
    • 70349770695 scopus 로고    scopus 로고
    • Epidemiology and natural history of nonalcoholic steatohepatitis
    • Argo CK, Caldwell SH. Epidemiology and natural history of nonalcoholic steatohepatitis. Clin Liver Dis. 2009;13:511-531.
    • (2009) Clin Liver Dis , vol.13 , pp. 511-531
    • Argo, C.K.1    Caldwell, S.H.2
  • 4
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology. 2010;51:1820-1832.
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 5
    • 77955690182 scopus 로고    scopus 로고
    • Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites
    • Neuschwander-Tetri BA. Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology. 2010;52:774-788.
    • (2010) Hepatology , vol.52 , pp. 774-788
    • Neuschwander-Tetri, B.A.1
  • 6
    • 84901944641 scopus 로고    scopus 로고
    • The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
    • Perry RJ, Samuel VT, Petersen KF, Shulman GI. The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature. 2014;510:84-91.
    • (2014) Nature , vol.510 , pp. 84-91
    • Perry, R.J.1    Samuel, V.T.2    Petersen, K.F.3    Shulman, G.I.4
  • 8
    • 84880057119 scopus 로고    scopus 로고
    • Dynamic regulation of hepatic lipid droplet properties by diet
    • Crunk AE, Monks J, Murakami A, et al. Dynamic regulation of hepatic lipid droplet properties by diet. PLoS One. 2013;8:e67631.
    • (2013) Plos One , vol.8
    • Crunk, A.E.1    Monks, J.2    Murakami, A.3
  • 9
    • 66349128492 scopus 로고    scopus 로고
    • PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
    • Bickel PE, Tansey JT, Welte MA. PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores. Biochim Biophys Acta. 2009;1791:419-440.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 419-440
    • Bickel, P.E.1    Tansey, J.T.2    Welte, M.A.3
  • 10
    • 30544452121 scopus 로고    scopus 로고
    • Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet
    • Motomura W, Inoue M, Ohtake T, Takahashi N, et al. Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet. Biochem Biophys Res Commun. 2006;340: 1111-1118.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 1111-1118
    • Motomura, W.1    Inoue, M.2    Ohtake, T.3    Takahashi, N.4
  • 11
    • 84859740874 scopus 로고    scopus 로고
    • Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice
    • Carr RM, Patel RT, Rao V, et al. Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice. Am J Physiol Regul Integr Comp Physiol. 2012;302:R996-R1003.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. RR996-R1003
    • Carr, R.M.1    Patel, R.T.2    Rao, V.3
  • 12
    • 84923489646 scopus 로고    scopus 로고
    • Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis
    • Wang C, Zhao Y, Gao X, et al. Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis. Hepatology. 2015;61:870-882.
    • (2015) Hepatology , vol.61 , pp. 870-882
    • Wang, C.1    Zhao, Y.2    Gao, X.3
  • 13
    • 33745942915 scopus 로고    scopus 로고
    • Adipocyte differentiationrelated protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins
    • Magnusson B, Asp L, Boström P, et al. Adipocyte differentiationrelated protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins. Arterioscler Thromb Vasc Biol. 2006;26:1566-1571.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1566-1571
    • Magnusson, B.1    Asp, L.2    Boström, P.3
  • 14
    • 31344437783 scopus 로고    scopus 로고
    • Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein
    • Chang BH, Li L, Paul A, et al. Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein. Mol Cell Biol. 2006;26:1063-1076.
    • (2006) Mol Cell Biol , vol.26 , pp. 1063-1076
    • Chang, B.H.1    Li, L.2    Paul, A.3
  • 15
    • 34247641706 scopus 로고    scopus 로고
    • Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide
    • Imai Y, Varela GM, Jackson MB, Graham MJ, Crooke RM, Ahima RS. Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide. Gastroenterology. 2007;132:1947-1954.
    • (2007) Gastroenterology , vol.132 , pp. 1947-1954
    • Imai, Y.1    Varela, G.M.2    Jackson, M.B.3    Graham, M.J.4    Crooke, R.M.5    Ahima, R.S.6
  • 16
    • 84876787028 scopus 로고    scopus 로고
    • Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
    • McManaman JL, Bales ES, Orlicky DJ, et al. Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res. 2013;54:1346-1359.
    • (2013) J Lipid Res , vol.54 , pp. 1346-1359
    • McManaman, J.L.1    Bales, E.S.2    Orlicky, D.J.3
  • 18
    • 84861742465 scopus 로고    scopus 로고
    • LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets
    • Li H, Song Y, Zhang LJ, et al. LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets. PLoS One. 2012;7:e36712.
    • (2012) Plos One , vol.7 , pp. e36712
    • Li, H.1    Song, Y.2    Zhang, L.J.3
  • 19
    • 84906224001 scopus 로고    scopus 로고
    • PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle
    • Mason RR, Mokhtar R, Matzaris M, et al. PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle. Mol Metab. 2014;3:652-663.
    • (2014) Mol Metab , vol.3 , pp. 652-663
    • Mason, R.R.1    Mokhtar, R.2    Matzaris, M.3
  • 20
    • 84873261154 scopus 로고    scopus 로고
    • Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression
    • Imai Y, Boyle S, Varela GM, et al. Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression. Physiol Genomics. 2012;44:1125-1131.
    • (2012) Physiol Genomics , vol.44 , pp. 1125-1131
    • Imai, Y.1    Boyle, S.2    Varela, G.M.3
  • 21
    • 84862025421 scopus 로고    scopus 로고
    • Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
    • Sun Z, Miller RA, Patel RT, et al. Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nat Med. 2012;18:934-942.
    • (2012) Nat Med , vol.18 , pp. 934-942
    • Sun, Z.1    Miller, R.A.2    Patel, R.T.3
  • 22
    • 59149104232 scopus 로고    scopus 로고
    • Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation
    • Granneman JG, Moore HP, Mottillo EP, Zhu Z. Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation. J Biol Chem. 2009;284:3049-3057.
    • (2009) J Biol Chem , vol.284 , pp. 3049-3057
    • Granneman, J.G.1    Moore, H.P.2    Mottillo, E.P.3    Zhu, Z.4
  • 23
    • 79953160438 scopus 로고    scopus 로고
    • Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase
    • Granneman JG, Moore HP, Mottillo EP, Zhu Z, Zhou L. Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase. J Biol Chem. 2011;286:5126-5135.
    • (2011) J Biol Chem , vol.286 , pp. 5126-5135
    • Granneman, J.G.1    Moore, H.P.2    Mottillo, E.P.3    Zhu, Z.4    Zhou, L.5
  • 24
    • 79955549893 scopus 로고    scopus 로고
    • Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein
    • Wang H, Bell M, Sreenivasan U, et al. Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. J Biol Chem. 2011;286:15707-15715.
    • (2011) J Biol Chem , vol.286 , pp. 15707-15715
    • Wang, H.1    Bell, M.2    Sreenivasan, U.3
  • 25
    • 80455135722 scopus 로고    scopus 로고
    • Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
    • Wang H, Sreenivasan U, Sreenevasan U, et al. Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria. J Lipid Res. 2011;52:2159-2168.
    • (2011) J Lipid Res , vol.52 , pp. 2159-2168
    • Wang, H.1    Sreenivasan, U.2    Sreenevasan, U.3
  • 26
    • 50949107027 scopus 로고    scopus 로고
    • Consequences of lipid droplet coat protein downregulation in liver cells: Abnormal lipid droplet metabolism and induction of insulin resistance
    • Bell M, Wang H, Chen H, et al. Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes. 2008;57: 2037-2045.
    • (2008) Diabetes , vol.57 , pp. 2037-2045
    • Bell, M.1    Wang, H.2    Chen, H.3
  • 28
    • 84962020084 scopus 로고    scopus 로고
    • Perilipin 5 regulates islet lipid metabolism and insulin secretion in a CAMP-dependent manner: Implication of its role in the postprandial insulin secretion
    • Trevino MB, Machida Y, Hallinger DR, et al. Perilipin 5 regulates islet lipid metabolism and insulin secretion in a CAMP-dependent manner: implication of its role in the postprandial insulin secretion. Diabetes. 2015;64:1299-1310.
    • (2015) Diabetes , vol.64 , pp. 1299-1310
    • Trevino, M.B.1    Machida, Y.2    Hallinger, D.R.3
  • 29
    • 34250854576 scopus 로고    scopus 로고
    • An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues
    • Viegas MS, Martins TC, Seco F, do Carmo A. An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues. Eur J Histochem. 2007;51:59-66.
    • (2007) Eur J Histochem , vol.51 , pp. 59-66
    • Viegas, M.S.1    Martins, T.C.2    Seco, F.3    Do Carmo, A.4
  • 30
    • 79952119926 scopus 로고    scopus 로고
    • Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: Focus on characterization of mitochondrial cardiolipins and monolysocardiolipins
    • Bird SS, Marur VR, Sniatynski MJ, Greenberg HK, Kristal BS. Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins. Anal Chem. 2011;83:940-949.
    • (2011) Anal Chem , vol.83 , pp. 940-949
    • Bird, S.S.1    Marur, V.R.2    Sniatynski, M.J.3    Greenberg, H.K.4    Kristal, B.S.5
  • 31
    • 80052305736 scopus 로고    scopus 로고
    • Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: Focus on triglyceride detection and characterization
    • Bird SS, Marur VR, Sniatynski MJ, Greenberg HK, Kristal BS. Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: focus on triglyceride detection and characterization. Anal Chem. 2011;83:6648-6657.
    • (2011) Anal Chem , vol.83 , pp. 6648-6657
    • Bird, S.S.1    Marur, V.R.2    Sniatynski, M.J.3    Greenberg, H.K.4    Kristal, B.S.5
  • 32
    • 84875828716 scopus 로고    scopus 로고
    • Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction
    • Wang H, Sreenivasan U, Gong DW, et al. Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction. J Lipid Res. 2013;54:953-965.
    • (2013) J Lipid Res , vol.54 , pp. 953-965
    • Wang, H.1    Sreenivasan, U.2    Gong, D.W.3
  • 33
    • 84875856324 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier
    • Pollak NM, Schweiger M, Jaeger D, et al. Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier. J Lipid Res. 2013;54:1092-1102.
    • (2013) J Lipid Res , vol.54 , pp. 1092-1102
    • Pollak, N.M.1    Schweiger, M.2    Jaeger, D.3
  • 34
    • 84866177989 scopus 로고    scopus 로고
    • Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress
    • Chitraju C, Trötzmüller M, Hartler J, et al. Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress. J Lipid Res. 2012;53:2141-2152.
    • (2012) J Lipid Res , vol.53 , pp. 2141-2152
    • Chitraju, C.1    Trötzmüller, M.2    Hartler, J.3
  • 35
    • 34147152663 scopus 로고    scopus 로고
    • Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic
    • Bartz R, Li WH, Venables B, et al. Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic. J Lipid Res. 2007;48:837-847.
    • (2007) J Lipid Res , vol.48 , pp. 837-847
    • Bartz, R.1    Li, W.H.2    Venables, B.3
  • 36
    • 84907984591 scopus 로고    scopus 로고
    • CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance
    • Raichur S, Wang ST, Chan PW, et al. CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metab. 2014;20:687-695.
    • (2014) Cell Metab , vol.20 , pp. 687-695
    • Raichur, S.1    Wang, S.T.2    Chan, P.W.3
  • 37
    • 84907978697 scopus 로고    scopus 로고
    • Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance
    • Turpin SM, Nicholls HT, Willmes DM, et al. Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab. 2014;20:678-686.
    • (2014) Cell Metab , vol.20 , pp. 678-686
    • Turpin, S.M.1    Nicholls, H.T.2    Willmes, D.M.3
  • 38
    • 68149098866 scopus 로고    scopus 로고
    • Identification of a physiologically relevant endogenous ligand for PPARα in liver
    • Chakravarthy MV, Lodhi IJ, Yin L, et al. Identification of a physiologically relevant endogenous ligand for PPARα in liver. Cell. 2009;138:476-488.
    • (2009) Cell , vol.138 , pp. 476-488
    • Chakravarthy, M.V.1    Lodhi, I.J.2    Yin, L.3
  • 39
    • 84895514508 scopus 로고    scopus 로고
    • Alterations of pancreatic islet structure, metabolism and gene expression in diet-induced obese C57BL/6J mice
    • Roat R, Rao V, Doliba NM, et al. Alterations of pancreatic islet structure, metabolism and gene expression in diet-induced obese C57BL/6J mice. PLoS One. 2014;9:e86815.
    • (2014) Plos One , vol.9 , pp. e86815
    • Roat, R.1    Rao, V.2    Doliba, N.M.3
  • 40
    • 84897023312 scopus 로고    scopus 로고
    • Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization
    • Kimmel AR, Sztalryd C. Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization. Curr Opin Lipidol. 2014;25: 110-117.
    • (2014) Curr Opin Lipidol , vol.25 , pp. 110-117
    • Kimmel, A.R.1    Sztalryd, C.2
  • 41
    • 78149346457 scopus 로고    scopus 로고
    • CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance
    • Brown JM, Betters JL, Lord C, et al. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. J Lipid Res. 2010;51:3306-3315.
    • (2010) J Lipid Res , vol.51 , pp. 3306-3315
    • Brown, J.M.1    Betters, J.L.2    Lord, C.3
  • 42
    • 79959550724 scopus 로고    scopus 로고
    • Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
    • Wu JW, Wang SP, Alvarez F, et al. Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. Hepatology. 2011;54:122-132.
    • (2011) Hepatology , vol.54 , pp. 122-132
    • Wu, J.W.1    Wang, S.P.2    Alvarez, F.3
  • 43
    • 84922269099 scopus 로고    scopus 로고
    • The interplay of protein kinase a and perilipin 5 regulates cardiac lipolysis
    • Pollak NM, Jaeger D, Kolleritsch S, et al. The interplay of protein kinase a and perilipin 5 regulates cardiac lipolysis. J Biol Chem. 2015;290:1295-1306.
    • (2015) J Biol Chem , vol.290 , pp. 1295-1306
    • Pollak, N.M.1    Jaeger, D.2    Kolleritsch, S.3
  • 44
    • 84873729674 scopus 로고    scopus 로고
    • Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity
    • Bosma M, Sparks LM, Hooiveld GJ, et al. Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity. Biochim Biophys Acta. 2013;1831:844-852.
    • (2013) Biochim Biophys Acta , vol.1831 , pp. 844-852
    • Bosma, M.1    Sparks, L.M.2    Hooiveld, G.J.3
  • 45
    • 84858020291 scopus 로고    scopus 로고
    • FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling
    • Zechner R, Zimmermann R, Eichmann TO, et al. FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling. Cell Metab. 2012;15:279-291.
    • (2012) Cell Metab , vol.15 , pp. 279-291
    • Zechner, R.1    Zimmermann, R.2    Eichmann, T.O.3
  • 46
    • 84899573610 scopus 로고    scopus 로고
    • Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism
    • Ong KT, Mashek MT, Davidson NO, Mashek DG. Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism. J Lipid Res. 2014;55:808-815.
    • (2014) J Lipid Res , vol.55 , pp. 808-815
    • Ong, K.T.1    Mashek, M.T.2    Davidson, N.O.3    Mashek, D.G.4
  • 47
    • 84873178604 scopus 로고    scopus 로고
    • CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
    • Cantley JL, Yoshimura T, Camporez JP, et al. CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance. Proc Natl Acad Sci USA. 2013;110:1869-1874.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 1869-1874
    • Cantley, J.L.1    Yoshimura, T.2    Camporez, J.P.3
  • 48
    • 84863614584 scopus 로고    scopus 로고
    • Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation
    • Kuramoto K, Okamura T, Yamaguchi T, et al. Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem. 2012;287:23852-23863.
    • (2012) J Biol Chem , vol.287 , pp. 23852-23863
    • Kuramoto, K.1    Okamura, T.2    Yamaguchi, T.3
  • 49
    • 80053927108 scopus 로고    scopus 로고
    • Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:Phosphocholine cytidylyltransferase
    • Krahmer N, Guo Y, Wilfling F, et al. Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metab. 2011;14: 504-515.
    • (2011) Cell Metab , vol.14 , pp. 504-515
    • Krahmer, N.1    Guo, Y.2    Wilfling, F.3
  • 50
    • 84895735915 scopus 로고    scopus 로고
    • Review: Biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites
    • Pol A, Gross SP, Parton RG. Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol. 2014;204: 635-646.
    • (2014) J Cell Biol , vol.204 , pp. 635-646
    • Pol, A.1    Gross, S.P.2    Parton, R.G.3
  • 51
    • 38849134279 scopus 로고    scopus 로고
    • Adenovirus serotype 5 hexon mediates liver gene transfer
    • Waddington SN, McVey JH, Bhella D, et al. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell. 2008;132:397-409.
    • (2008) Cell , vol.132 , pp. 397-409
    • Waddington, S.N.1    McVey, J.H.2    Bhella, D.3
  • 52
    • 80055019114 scopus 로고    scopus 로고
    • A cluster of basic amino acids in the factor X serine protease mediates surface attachment of adenovirus/FX complexes
    • Duffy MR, Bradshaw AC, Parker AL, McVey JH, Baker AH. A cluster of basic amino acids in the factor X serine protease mediates surface attachment of adenovirus/FX complexes. J Virol. 2011;85: 10914-10919.
    • (2011) J Virol , vol.85 , pp. 10914-10919
    • Duffy, M.R.1    Bradshaw, A.C.2    Parker, A.L.3    McVey, J.H.4    Baker, A.H.5
  • 53
    • 33745278034 scopus 로고    scopus 로고
    • Conditional deletion of c-myc does not impair liver regeneration
    • Li F, Xiang Y, Potter J, Dinavahi R, Dang CV, Lee LA. Conditional deletion of c-myc does not impair liver regeneration. Cancer Res. 2006;66:5608-5612.
    • (2006) Cancer Res , vol.66 , pp. 5608-5612
    • Li, F.1    Xiang, Y.2    Potter, J.3    Dinavahi, R.4    Dang, C.V.5    Lee, L.A.6
  • 54
    • 84879773624 scopus 로고    scopus 로고
    • Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks
    • Saini C, Liani A, Curie T, et al. Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks. Genes Dev. 2013;27:1526-1536.
    • (2013) Genes Dev , vol.27 , pp. 1526-1536
    • Saini, C.1    Liani, A.2    Curie, T.3
  • 55
    • 84873873215 scopus 로고    scopus 로고
    • The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
    • Deng Y, Wang ZV, Tao C, et al. The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. J Clin Invest. 2013;123: 455-468.
    • (2013) J Clin Invest , vol.123 , pp. 455-468
    • Deng, Y.1    Wang, Z.V.2    Tao, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.