Conformational states of a soluble, uncleaved HIV-1 envelope trimer

Journal of Virology

Volumn 91, Issue 10, 2017, Pages

  Liu, Yuhang ^a,b,e   Pan, Junhua ^a,c   Cai, Yongfei ^a   Grigorieff, Nikolaus ^b   Harrison, Stephen C ^a,c,d   Chen, Bing ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e PFIZER INC   (United States)

Author keywords

cryoEM; Envelope; Human immunodeficiency virus; Immunogen

Indexed keywords

ARTICLE; CRYOELECTRON MICROSCOPY; GEL FILTRATION CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SURFACE PLASMON RESONANCE; VACCINE PRODUCTION; VIRUS MORPHOLOGY; CHEMISTRY; CONFORMATION; GENETICS; IMMUNOLOGY; METABOLISM; PROTEIN DEGRADATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; SOLUBILITY;

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT VACCINE; VIRUS ENVELOPE PROTEIN;

ANTIBODIES, NEUTRALIZING; CRYOELECTRON MICROSCOPY; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; MOLECULAR CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; SOLUBILITY; VACCINES, SYNTHETIC;

EID: 85018259958     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00175-17     Document Type: Article

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