Mitochondrial energy imbalance and lipid peroxidation cause cell death in friedreich’s ataxia

Cell Death and Disease

Volumn 7, Issue 5, 2016, Pages

  Abeti, R ^a   Parkinson, M H ^a   Hargreaves, I P ^b   Angelova, P R ^a   Sandi, C ^c,d   Pook, M A ^c   Giunti, P ^a   Abramov, A Y ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b National Hospital   (United Kingdom)

^c BRUNEL UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); IRON; IRON BINDING PROTEIN; UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; FRIEDREICH ATAXIA; GLIA CELL; GRANULE CELL; HUMAN; LIPID PEROXIDATION; LIVE CELL IMAGING; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; ANIMAL; CEREBELLUM; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NERVE CELL; OXIDATIVE STRESS; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANIMALS; CEREBELLUM; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; FRIEDREICH ATAXIA; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; IRON; IRON-BINDING PROTEINS; LIPID PEROXIDATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MUTATION; NEURONS; OXIDATIVE STRESS; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85017618880     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2016.111     Document Type: Article

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