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Volumn , Issue , 2017, Pages 1-20

Overview of Nicotine Withdrawal and Negative Reinforcement (Preclinical)

Author keywords

Abstinence; Addiction; Animal model; Dependence; Escalation; Minipump; Self administration; Smoke; Tobacco; Vapor

Indexed keywords


EID: 85017456971     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-802574-1.00001-6     Document Type: Chapter
Times cited : (9)

References (129)
  • 2
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Press, Washington, DC
    • American Psychiatric Association Diagnostic and statistical manual of mental disorders 2000, American Psychiatric Press, Washington, DC. 4th ed., text revision.
    • (2000) Diagnostic and statistical manual of mental disorders
  • 3
    • 0037066055 scopus 로고    scopus 로고
    • Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons
    • Azam L., Winzer-Serhan U.H., Chen Y., Leslie F.M. Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons. Journal of Comparative Neurology 2002, 444:260-274.
    • (2002) Journal of Comparative Neurology , vol.444 , pp. 260-274
    • Azam, L.1    Winzer-Serhan, U.H.2    Chen, Y.3    Leslie, F.M.4
  • 5
    • 0024215844 scopus 로고
    • Drug therapy: pharmacologic aspects of cigarette smoking and nicotine addiction
    • Benowitz N.L. Drug therapy: pharmacologic aspects of cigarette smoking and nicotine addiction. The New England Journal of Medicine 1988, 319:1318-1330.
    • (1988) The New England Journal of Medicine , vol.319 , pp. 1318-1330
    • Benowitz, N.L.1
  • 7
    • 0021266137 scopus 로고
    • Nicotine and carbon monoxide intake from high- and low-yield cigarettes
    • Benowitz N.L., Jacob P. Nicotine and carbon monoxide intake from high- and low-yield cigarettes. Clinical Pharmacology and Therapeutics 1984, 36:265-270.
    • (1984) Clinical Pharmacology and Therapeutics , vol.36 , pp. 265-270
    • Benowitz, N.L.1    Jacob, P.2
  • 8
    • 0023715754 scopus 로고
    • Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum
    • Benowitz N.L., Porchet H., Sheiner L., Jacob P. Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clinical Pharmacology and Therapeutics 1988, 44:23-28.
    • (1988) Clinical Pharmacology and Therapeutics , vol.44 , pp. 23-28
    • Benowitz, N.L.1    Porchet, H.2    Sheiner, L.3    Jacob, P.4
  • 9
    • 0018391425 scopus 로고
    • Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles
    • Benwell M.E., Balfour D.J. Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles. Psychopharmacology 1979, 63:7-11.
    • (1979) Psychopharmacology , vol.63 , pp. 7-11
    • Benwell, M.E.1    Balfour, D.J.2
  • 10
    • 26244465185 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor-like peptides in cannabis, nicotine, and alcohol dependence
    • Bruijnzeel A.W., Gold M.S. The role of corticotropin-releasing factor-like peptides in cannabis, nicotine, and alcohol dependence. Brain Research Reviews 2005, 49:505-528.
    • (2005) Brain Research Reviews , vol.49 , pp. 505-528
    • Bruijnzeel, A.W.1    Gold, M.S.2
  • 11
    • 0024478412 scopus 로고
    • 5HT3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward
    • Carboni E., Acquas E., Leone P., Di Chiara G. 5HT3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward. Psychopharmacology 1989, 97:175-178.
    • (1989) Psychopharmacology , vol.97 , pp. 175-178
    • Carboni, E.1    Acquas, E.2    Leone, P.3    Di Chiara, G.4
  • 12
    • 0022350728 scopus 로고
    • Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons
    • Clarke P.B.S., Pert A. Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons. Brain Research 1985, 348:355-358.
    • (1985) Brain Research , vol.348 , pp. 355-358
    • Clarke, P.B.S.1    Pert, A.2
  • 13
    • 84884559568 scopus 로고    scopus 로고
    • Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking
    • Cohen A., George O. Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking. Frontiers in Psychiatry 2013, 4:41.
    • (2013) Frontiers in Psychiatry , vol.4 , pp. 41
    • Cohen, A.1    George, O.2
  • 14
    • 84863984846 scopus 로고    scopus 로고
    • Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence
    • Cohen A., Koob G.F., George O. Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence. Neuropsychopharmacology 2012, 37:2153-2160.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2153-2160
    • Cohen, A.1    Koob, G.F.2    George, O.3
  • 16
    • 0033085846 scopus 로고    scopus 로고
    • Nicotine self-administration in animals as a dependence model
    • Corrigall W.A. Nicotine self-administration in animals as a dependence model. Nicotine and Tobacco Research 1999, 1:11-20.
    • (1999) Nicotine and Tobacco Research , vol.1 , pp. 11-20
    • Corrigall, W.A.1
  • 17
    • 0024436910 scopus 로고
    • Nicotine maintains robust self-administration in rats on a limited-access schedule
    • Corrigall W.A., Coen K.M. Nicotine maintains robust self-administration in rats on a limited-access schedule. Psychopharmacology 1989, 99:473-478.
    • (1989) Psychopharmacology , vol.99 , pp. 473-478
    • Corrigall, W.A.1    Coen, K.M.2
  • 18
    • 0025869798 scopus 로고
    • Selective dopamine antagonists reduce nicotine self-administration
    • Corrigall W.A., Coen K.M. Selective dopamine antagonists reduce nicotine self-administration. Psychopharmacology 1991, 104:171-176.
    • (1991) Psychopharmacology , vol.104 , pp. 171-176
    • Corrigall, W.A.1    Coen, K.M.2
  • 19
    • 0027991930 scopus 로고
    • Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
    • Corrigall W.A., Coen K.M., Adamson K.L. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Research 1994, 653:278-284.
    • (1994) Brain Research , vol.653 , pp. 278-284
    • Corrigall, W.A.1    Coen, K.M.2    Adamson, K.L.3
  • 20
    • 0034091651 scopus 로고    scopus 로고
    • Response of nicotine self-administration in the rat to manipulations of mu-opioid and γ-aminobutyric acid receptors in the ventral tegmental area
    • Corrigall W.A., Coen K.M., Adamson K.L., Chow B.L., Zhang J. Response of nicotine self-administration in the rat to manipulations of mu-opioid and γ-aminobutyric acid receptors in the ventral tegmental area. Psychopharmacology 2000, 149:107-114.
    • (2000) Psychopharmacology , vol.149 , pp. 107-114
    • Corrigall, W.A.1    Coen, K.M.2    Adamson, K.L.3    Chow, B.L.4    Zhang, J.5
  • 21
    • 0034750874 scopus 로고    scopus 로고
    • GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat
    • Corrigall W.A., Coen K.M., Zhang J., Adamson K.L. GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat. Psychopharmacology 2001, 158:190-197.
    • (2001) Psychopharmacology , vol.158 , pp. 190-197
    • Corrigall, W.A.1    Coen, K.M.2    Zhang, J.3    Adamson, K.L.4
  • 22
    • 0026521447 scopus 로고
    • The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine
    • Corrigall W.A., Franklin K.B.J., Coen K.M., Clarke P.B.S. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology 1992, 107:285-289.
    • (1992) Psychopharmacology , vol.107 , pp. 285-289
    • Corrigall, W.A.1    Franklin, K.B.J.2    Coen, K.M.3    Clarke, P.B.S.4
  • 23
    • 35148894062 scopus 로고    scopus 로고
    • Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning
    • Davis J.A., Kenney J.W., Gould T.J. Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning. The Journal of Neuroscience 2007, 27:10870-10877.
    • (2007) The Journal of Neuroscience , vol.27 , pp. 10870-10877
    • Davis, J.A.1    Kenney, J.W.2    Gould, T.J.3
  • 26
    • 84870938442 scopus 로고    scopus 로고
    • Acute restraint stress prevents nicotine-induced mesolimbic dopaminergic activation via a corticosterone-mediated mechanism: a microdialysis study in the rat
    • Enrico P., Sirca D., Mereu M., Peana A.T., Mercante B., Diana M. Acute restraint stress prevents nicotine-induced mesolimbic dopaminergic activation via a corticosterone-mediated mechanism: a microdialysis study in the rat. Drug and Alcohol Dependence 2013, 127:8-14.
    • (2013) Drug and Alcohol Dependence , vol.127 , pp. 8-14
    • Enrico, P.1    Sirca, D.2    Mereu, M.3    Peana, A.T.4    Mercante, B.5    Diana, M.6
  • 27
    • 0032492857 scopus 로고    scopus 로고
    • Dramatic decreases in brain reward function during nicotine withdrawal
    • Epping-Jordan M.P., Watkins S.S., Koob G.F., Markou A. Dramatic decreases in brain reward function during nicotine withdrawal. Nature 1998, 393:76-79.
    • (1998) Nature , vol.393 , pp. 76-79
    • Epping-Jordan, M.P.1    Watkins, S.S.2    Koob, G.F.3    Markou, A.4
  • 28
    • 22444436474 scopus 로고    scopus 로고
    • Strain and sex alter effects of stress and nicotine on feeding, body weight, and HPA axis hormones
    • Faraday M.M., Blakeman K.H., Grunberg N.E. Strain and sex alter effects of stress and nicotine on feeding, body weight, and HPA axis hormones. Pharmacology, Biochemistry, and Behavior 2005, 80:577-589.
    • (2005) Pharmacology, Biochemistry, and Behavior , vol.80 , pp. 577-589
    • Faraday, M.M.1    Blakeman, K.H.2    Grunberg, N.E.3
  • 30
    • 84887119512 scopus 로고    scopus 로고
    • Nicotine aversion: neurobiological mechanisms and relevance to tobacco dependence vulnerability
    • Fowler C.D., Kenny P.J. Nicotine aversion: neurobiological mechanisms and relevance to tobacco dependence vulnerability. Neuropharmacology 2014, 76(Pt B):533-544.
    • (2014) Neuropharmacology , vol.76 , pp. 533-544
    • Fowler, C.D.1    Kenny, P.J.2
  • 31
    • 79953246461 scopus 로고    scopus 로고
    • Habenular α5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler C.D., Lu Q., Johnson P.M., Marks M.J., Kenny P.J. Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature 2011, 471:597-601.
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 32
    • 0035890160 scopus 로고    scopus 로고
    • Norepinephrine secretion in the hypothalamic paraventricular nucleus of rats during unlimited access to self-administered nicotine: an in vivo microdialysis study
    • Fu Y., Matta S.G., Brower V.G., Sharp B.M. Norepinephrine secretion in the hypothalamic paraventricular nucleus of rats during unlimited access to self-administered nicotine: an in vivo microdialysis study. The Journal of Neuroscience 2001, 21:8979-8989.
    • (2001) The Journal of Neuroscience , vol.21 , pp. 8979-8989
    • Fu, Y.1    Matta, S.G.2    Brower, V.G.3    Sharp, B.M.4
  • 33
    • 0041696482 scopus 로고    scopus 로고
    • Norepinephrine release in amygdala of rats during chronic nicotine self-administration: an in vivo microdialysis study
    • Fu Y., Matta S.G., Kane V.B., Sharp B.M. Norepinephrine release in amygdala of rats during chronic nicotine self-administration: an in vivo microdialysis study. Neuropharmacology 2003, 45:514-523.
    • (2003) Neuropharmacology , vol.45 , pp. 514-523
    • Fu, Y.1    Matta, S.G.2    Kane, V.B.3    Sharp, B.M.4
  • 36
    • 27944492185 scopus 로고    scopus 로고
    • Mecamylamine increases extracellular CRF levels in the central nucleus of the amygdala or nicotine-dependent rats
    • Ghozland S., Zorrilla E., Parsons L.H., Koob G.F. Mecamylamine increases extracellular CRF levels in the central nucleus of the amygdala or nicotine-dependent rats. Society for Neuroscience 2004, 30. abstract# 708.8.
    • (2004) Society for Neuroscience , vol.30
    • Ghozland, S.1    Zorrilla, E.2    Parsons, L.H.3    Koob, G.F.4
  • 38
    • 0024160037 scopus 로고
    • Reinforcing effects of nicotine in humans and experimental animals responding under intermittent schedules of i.v. drug injection
    • Goldberg S.R., Henningfield J.E. Reinforcing effects of nicotine in humans and experimental animals responding under intermittent schedules of i.v. drug injection. Pharmacology, Biochemistry, and Behavior 1988, 30:227-234.
    • (1988) Pharmacology, Biochemistry, and Behavior , vol.30 , pp. 227-234
    • Goldberg, S.R.1    Henningfield, J.E.2
  • 39
    • 0020073372 scopus 로고
    • Maintenance and suppression of behavior by intravenous nicotine injections in squirrel monkeys
    • Goldberg S.R., Spealman R.D. Maintenance and suppression of behavior by intravenous nicotine injections in squirrel monkeys. Federation Proceedings 1982, 41:216-220.
    • (1982) Federation Proceedings , vol.41 , pp. 216-220
    • Goldberg, S.R.1    Spealman, R.D.2
  • 40
    • 0020693543 scopus 로고
    • Suppression of behavior by intravenous injections of nicotine or by electric shocks in squirrel monkeys: effects of chlordiazepoxide and mecamylamine
    • Goldberg S.R., Spealman R.D. Suppression of behavior by intravenous injections of nicotine or by electric shocks in squirrel monkeys: effects of chlordiazepoxide and mecamylamine. The Journal of Pharmacology and Experimental Therapeutics 1983, 224:334-340.
    • (1983) The Journal of Pharmacology and Experimental Therapeutics , vol.224 , pp. 334-340
    • Goldberg, S.R.1    Spealman, R.D.2
  • 41
    • 0019816913 scopus 로고
    • Persistent behavior at high rates maintained by intravenous self-administration of nicotine
    • Goldberg S.R., Spealman R.D., Goldberg D.M. Persistent behavior at high rates maintained by intravenous self-administration of nicotine. Science 1981, 214:573-575.
    • (1981) Science , vol.214 , pp. 573-575
    • Goldberg, S.R.1    Spealman, R.D.2    Goldberg, D.M.3
  • 43
    • 84893848184 scopus 로고    scopus 로고
    • Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications
    • Goniewicz M.L., Hajek P., McRobbie H. Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications. Addiction 2014, 109:500-507.
    • (2014) Addiction , vol.109 , pp. 500-507
    • Goniewicz, M.L.1    Hajek, P.2    McRobbie, H.3
  • 44
    • 84945488351 scopus 로고    scopus 로고
    • The reinforcing effects of nicotine in humans and nonhuman primates: a review of intravenous self-administration evidence and future directions for research
    • Goodwin A.K., Hiranita T., Paule M.G. The reinforcing effects of nicotine in humans and nonhuman primates: a review of intravenous self-administration evidence and future directions for research. Nicotine and Tobacco Research 2015, 17:1297-1310.
    • (2015) Nicotine and Tobacco Research , vol.17 , pp. 1297-1310
    • Goodwin, A.K.1    Hiranita, T.2    Paule, M.G.3
  • 45
    • 84891560664 scopus 로고    scopus 로고
    • Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning
    • Gould T.J., Leach P.T. Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning. Neurobiology of Learning and Memory 2014, 107:108-132.
    • (2014) Neurobiology of Learning and Memory , vol.107 , pp. 108-132
    • Gould, T.J.1    Leach, P.T.2
  • 47
    • 84926203391 scopus 로고    scopus 로고
    • VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation
    • Grieder T.E., Herman M.A., Contet C., Tan L.A., Vargas-Perez H., Cohen A., et al. VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience 2014, 17:1751-1758.
    • (2014) Nature Neuroscience , vol.17 , pp. 1751-1758
    • Grieder, T.E.1    Herman, M.A.2    Contet, C.3    Tan, L.A.4    Vargas-Perez, H.5    Cohen, A.6
  • 48
    • 25444488490 scopus 로고    scopus 로고
    • Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats
    • Guillem K., Vouillac C., Azar M.R., Parsons L.H., Koob G.F., Cador M., et al. Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats. The Journal of Neuroscience 2005, 25:8593-8600.
    • (2005) The Journal of Neuroscience , vol.25 , pp. 8593-8600
    • Guillem, K.1    Vouillac, C.2    Azar, M.R.3    Parsons, L.H.4    Koob, G.F.5    Cador, M.6
  • 50
    • 0031057228 scopus 로고    scopus 로고
    • Behavioral manifestations of the nicotine abstinence syndrome in the rat: peripheral versus central mechanisms
    • Hildebrand B.E., Nomikos G.G., Bondjers C., Nisell M., Svensson T.H. Behavioral manifestations of the nicotine abstinence syndrome in the rat: peripheral versus central mechanisms. Psychopharmacology 1997, 129:348-356.
    • (1997) Psychopharmacology , vol.129 , pp. 348-356
    • Hildebrand, B.E.1    Nomikos, G.G.2    Bondjers, C.3    Nisell, M.4    Svensson, T.H.5
  • 51
    • 0031975975 scopus 로고    scopus 로고
    • Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome
    • Hildebrand B.E., Nomikos G.G., Hertel P., Schilstrom B., Svensson T.H. Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Brain Research 1998, 779:214-225.
    • (1998) Brain Research , vol.779 , pp. 214-225
    • Hildebrand, B.E.1    Nomikos, G.G.2    Hertel, P.3    Schilstrom, B.4    Svensson, T.H.5
  • 52
    • 0032883782 scopus 로고    scopus 로고
    • Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area
    • Hildebrand B.E., Panagis G., Svensson T.H., Nomikos G.G. Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area. Neuropsychopharmacology 1999, 21:560-574.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 560-574
    • Hildebrand, B.E.1    Panagis, G.2    Svensson, T.H.3    Nomikos, G.G.4
  • 53
    • 0026030445 scopus 로고
    • Nicotine-induced alteration in Tyr-Gly-Gly and Met-enkephalin in discrete brain nuclei reflects altered enkephalin neuron activity
    • Houdi A.A., Pierzchala K., Marson L., Palkovits M., Van Loon G.R. Nicotine-induced alteration in Tyr-Gly-Gly and Met-enkephalin in discrete brain nuclei reflects altered enkephalin neuron activity. Peptides 1991, 12:161-166.
    • (1991) Peptides , vol.12 , pp. 161-166
    • Houdi, A.A.1    Pierzchala, K.2    Marson, L.3    Palkovits, M.4    Van Loon, G.R.5
  • 56
    • 0015496629 scopus 로고
    • Cigarette smoking and plasma levels of nicotine
    • Isaac P.F., Rand M.J. Cigarette smoking and plasma levels of nicotine. Nature 1972, 236:308-310.
    • (1972) Nature , vol.236 , pp. 308-310
    • Isaac, P.F.1    Rand, M.J.2
  • 58
    • 84930868118 scopus 로고    scopus 로고
    • Individual differences in the reinforcing and punishing effects of nicotine in rhesus monkeys
    • Koffarnus M.N., Winger G. Individual differences in the reinforcing and punishing effects of nicotine in rhesus monkeys. Psychopharmacology 2015, 232:2393-2403.
    • (2015) Psychopharmacology , vol.232 , pp. 2393-2403
    • Koffarnus, M.N.1    Winger, G.2
  • 59
    • 0033232472 scopus 로고    scopus 로고
    • Corticotropin-releasing factor, norepinephrine and stress
    • Koob G.F. Corticotropin-releasing factor, norepinephrine and stress. Biological Psychiatry 1999, 46:1167-1180.
    • (1999) Biological Psychiatry , vol.46 , pp. 1167-1180
    • Koob, G.F.1
  • 60
    • 0023763088 scopus 로고
    • Cellular and molecular mechanisms of drug dependence
    • Koob G.F., Bloom F.E. Cellular and molecular mechanisms of drug dependence. Science 1988, 242:715-723.
    • (1988) Science , vol.242 , pp. 715-723
    • Koob, G.F.1    Bloom, F.E.2
  • 61
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: hedonic homeostatic dysregulation
    • Koob G.F., Le Moal M. Drug abuse: hedonic homeostatic dysregulation. Science 1997, 278:52-58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Le Moal, M.2
  • 62
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob G.F., Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 2001, 24:97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 63
    • 27644548739 scopus 로고    scopus 로고
    • Plasticity of reward neurocircuitry and the "dark side" of drug addiction
    • Koob G.F., Le Moal M. Plasticity of reward neurocircuitry and the "dark side" of drug addiction. Nature Neuroscience 2005, 8:1442-1444.
    • (2005) Nature Neuroscience , vol.8 , pp. 1442-1444
    • Koob, G.F.1    Le Moal, M.2
  • 67
    • 0032169803 scopus 로고    scopus 로고
    • Neuroscience of addiction
    • Koob G.F., Sanna P.P., Bloom F.E. Neuroscience of addiction. Neuron 1998, 21:467-476.
    • (1998) Neuron , vol.21 , pp. 467-476
    • Koob, G.F.1    Sanna, P.P.2    Bloom, F.E.3
  • 68
    • 0344944249 scopus 로고    scopus 로고
    • Effects of continuous nicotine infusion on nicotine self-administration in rats: relationship between continuously infused and self-administered nicotine doses and serum concentrations
    • LeSage M.G., Keyler D.E., Collins G., Pentel P.R. Effects of continuous nicotine infusion on nicotine self-administration in rats: relationship between continuously infused and self-administered nicotine doses and serum concentrations. Psychopharmacology 2003, 170:278-286.
    • (2003) Psychopharmacology , vol.170 , pp. 278-286
    • LeSage, M.G.1    Keyler, D.E.2    Collins, G.3    Pentel, P.R.4
  • 70
    • 0031242019 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in health and disease
    • Lindstrom J. Nicotinic acetylcholine receptors in health and disease. Molecular Neurobiology 1997, 15:193-222.
    • (1997) Molecular Neurobiology , vol.15 , pp. 193-222
    • Lindstrom, J.1
  • 71
    • 0032898312 scopus 로고    scopus 로고
    • Abstinence and price effects on demand for cigarettes: a behavioral-economic analysis
    • Madden G.J., Bickel W.K. Abstinence and price effects on demand for cigarettes: a behavioral-economic analysis. Addiction 1999, 94:577-588.
    • (1999) Addiction , vol.94 , pp. 577-588
    • Madden, G.J.1    Bickel, W.K.2
  • 75
    • 0032031305 scopus 로고    scopus 로고
    • Neurobiological similarities in depression and drug dependence: a self-medication hypothesis
    • Markou A., Kosten T.R., Koob G.F. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology 1998, 18:135-174.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 135-174
    • Markou, A.1    Kosten, T.R.2    Koob, G.F.3
  • 76
    • 21844438972 scopus 로고    scopus 로고
    • Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
    • Maskos U., Molles B.E., Pons S., Besson M., Guiard B.P., Guilloux J.P., et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature 2005, 436:103-107.
    • (2005) Nature , vol.436 , pp. 103-107
    • Maskos, U.1    Molles, B.E.2    Pons, S.3    Besson, M.4    Guiard, B.P.5    Guilloux, J.P.6
  • 79
    • 0031417361 scopus 로고    scopus 로고
    • Nicotinic activation of CRH neurons in extrahypothalamic regions of the rat brain
    • Matta S.G., Valentine J.D., Sharp B.M. Nicotinic activation of CRH neurons in extrahypothalamic regions of the rat brain. Endocrine 1997, 7:245-253.
    • (1997) Endocrine , vol.7 , pp. 245-253
    • Matta, S.G.1    Valentine, J.D.2    Sharp, B.M.3
  • 80
    • 0029096914 scopus 로고
    • Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
    • McGehee D.S., Heath M.J., Gelber S., Devay P., Role L.W. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 1995, 269:1692-1696.
    • (1995) Science , vol.269 , pp. 1692-1696
    • McGehee, D.S.1    Heath, M.J.2    Gelber, S.3    Devay, P.4    Role, L.W.5
  • 81
  • 82
    • 84904989473 scopus 로고    scopus 로고
    • Nicotine consumption is regulated by a human polymorphism in dopamine neurons
    • Morel C., Fattore L., Pons S., Hay Y.A., Marti F., Lambolez B., et al. Nicotine consumption is regulated by a human polymorphism in dopamine neurons. Molecular Psychiatry 2014, 19:930-936.
    • (2014) Molecular Psychiatry , vol.19 , pp. 930-936
    • Morel, C.1    Fattore, L.2    Pons, S.3    Hay, Y.A.4    Marti, F.5    Lambolez, B.6
  • 83
    • 0023192246 scopus 로고
    • Effects of smoking deprivation on smoking behavior and heart rate response in high and low CO absorbing smokers
    • Nil R., Woodson P.P., Battig K. Effects of smoking deprivation on smoking behavior and heart rate response in high and low CO absorbing smokers. Psychopharmacology 1987, 92:465-469.
    • (1987) Psychopharmacology , vol.92 , pp. 465-469
    • Nil, R.1    Woodson, P.P.2    Battig, K.3
  • 84
    • 0031018742 scopus 로고    scopus 로고
    • Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens
    • Nisell M., Marcus M., Nomikos G.G., Svensson T.H. Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens. Journal of Neural Transmission 1997, 104:1-10.
    • (1997) Journal of Neural Transmission , vol.104 , pp. 1-10
    • Nisell, M.1    Marcus, M.2    Nomikos, G.G.3    Svensson, T.H.4
  • 85
    • 0028031691 scopus 로고
    • Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
    • Nisell M., Nomikos G.G., Svensson T.H. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area. Synapse 1994, 16:36-44.
    • (1994) Synapse , vol.16 , pp. 36-44
    • Nisell, M.1    Nomikos, G.G.2    Svensson, T.H.3
  • 86
    • 0033577176 scopus 로고    scopus 로고
    • Nicotine withdrawal in the rat: role of α7 nicotinic receptors in the ventral tegmental area
    • Nomikos G.G., Hildebrand B.E., Panagis G., Svensson T.H. Nicotine withdrawal in the rat: role of α7 nicotinic receptors in the ventral tegmental area. Neuroreport 1999, 10:697-702.
    • (1999) Neuroreport , vol.10 , pp. 697-702
    • Nomikos, G.G.1    Hildebrand, B.E.2    Panagis, G.3    Svensson, T.H.4
  • 87
    • 0029056296 scopus 로고
    • Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area
    • Oakman S.A., Faris P.L., Kerr P.E., Cozzari C., Hartman B.K. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. The Journal of Neuroscience 1995, 15:5859-5869.
    • (1995) The Journal of Neuroscience , vol.15 , pp. 5859-5869
    • Oakman, S.A.1    Faris, P.L.2    Kerr, P.E.3    Cozzari, C.4    Hartman, B.K.5
  • 88
    • 0042707825 scopus 로고    scopus 로고
    • Extrahypothalamic corticotropin-releasing hormone mediates (-)-nicotine-induced elevation of plasma corticosterone in rats
    • Okada S., Shimizu T., Yokotani K. Extrahypothalamic corticotropin-releasing hormone mediates (-)-nicotine-induced elevation of plasma corticosterone in rats. European Journal of Pharmacology 2003, 473:217-223.
    • (2003) European Journal of Pharmacology , vol.473 , pp. 217-223
    • Okada, S.1    Shimizu, T.2    Yokotani, K.3
  • 89
    • 84861980092 scopus 로고    scopus 로고
    • Selective re-expression of β2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration
    • Orejarena M.J., Herrera-Solis A., Pons S., Maskos U., Maldonado R., Robledo P. Selective re-expression of β2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration. Neuropharmacology 2012, 63:235-241.
    • (2012) Neuropharmacology , vol.63 , pp. 235-241
    • Orejarena, M.J.1    Herrera-Solis, A.2    Pons, S.3    Maskos, U.4    Maldonado, R.5    Robledo, P.6
  • 92
    • 84941881425 scopus 로고    scopus 로고
    • Electronic cigarettes and vaping: a new challenge in clinical medicine and public health: a literature review
    • Palazzolo D.L. Electronic cigarettes and vaping: a new challenge in clinical medicine and public health: a literature review. Frontiers in Public Health 2013, 1:56.
    • (2013) Frontiers in Public Health , vol.1 , pp. 56
    • Palazzolo, D.L.1
  • 93
    • 0033991098 scopus 로고    scopus 로고
    • Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome
    • Panagis G., Hildebrand B.E., Svensson T.H., Nomikos G.G. Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse 2000, 35:15-25.
    • (2000) Synapse , vol.35 , pp. 15-25
    • Panagis, G.1    Hildebrand, B.E.2    Svensson, T.H.3    Nomikos, G.G.4
  • 94
    • 0035013883 scopus 로고    scopus 로고
    • Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain
    • Pandey S.C., Roy A., Xu T., Mittal N. Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain. Journal of Neurochemistry 2001, 77:943-952.
    • (2001) Journal of Neurochemistry , vol.77 , pp. 943-952
    • Pandey, S.C.1    Roy, A.2    Xu, T.3    Mittal, N.4
  • 95
    • 84902315409 scopus 로고    scopus 로고
    • Nicotine-induced increase of dopaminergic mesoaccumbal neuron activity is prevented by acute restraint stress: in vivo electrophysiology in rats
    • Panin F., Lintas A., Diana M. Nicotine-induced increase of dopaminergic mesoaccumbal neuron activity is prevented by acute restraint stress: in vivo electrophysiology in rats. European Neuropsychopharmacology 2014, 24:1175-1180.
    • (2014) European Neuropsychopharmacology , vol.24 , pp. 1175-1180
    • Panin, F.1    Lintas, A.2    Diana, M.3
  • 96
    • 2342461609 scopus 로고    scopus 로고
    • Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats
    • Paterson N.E., Markou A. Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats. Psychopharmacology 2004, 173:64-72.
    • (2004) Psychopharmacology , vol.173 , pp. 64-72
    • Paterson, N.E.1    Markou, A.2
  • 97
    • 0021706527 scopus 로고
    • Neuroregulators and the reinforcement of smoking: towards a biobehavioral explanation
    • Pomerleau O.F., Pomerleau C.S. Neuroregulators and the reinforcement of smoking: towards a biobehavioral explanation. Neuroscience and Biobehavioral Reviews 1984, 8:503-513.
    • (1984) Neuroscience and Biobehavioral Reviews , vol.8 , pp. 503-513
    • Pomerleau, O.F.1    Pomerleau, C.S.2
  • 98
    • 0026767674 scopus 로고
    • Euphoriant effects of nicotine in smokers
    • Pomerleau C.S., Pomerleau O.F. Euphoriant effects of nicotine in smokers. Psychopharmacology 1992, 108:460-465.
    • (1992) Psychopharmacology , vol.108 , pp. 460-465
    • Pomerleau, C.S.1    Pomerleau, O.F.2
  • 99
    • 58149385076 scopus 로고    scopus 로고
    • Crucial role of α4 and α6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
    • Pons S., Fattore L., Cossu G., Tolu S., Porcu E., McIntosh J.M., et al. Crucial role of α4 and α6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. The Journal of Neuroscience 2008, 28:12318-12327.
    • (2008) The Journal of Neuroscience , vol.28 , pp. 12318-12327
    • Pons, S.1    Fattore, L.2    Cossu, G.3    Tolu, S.4    Porcu, E.5    McIntosh, J.M.6
  • 100
  • 101
    • 0029943635 scopus 로고    scopus 로고
    • Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
    • Pontieri F.E., Tanda G., Orzi F., Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 1996, 382:255-257.
    • (1996) Nature , vol.382 , pp. 255-257
    • Pontieri, F.E.1    Tanda, G.2    Orzi, F.3    Di Chiara, G.4
  • 102
    • 0020686543 scopus 로고
    • A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion
    • Risner M.E., Goldberg S.R. A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion. The Journal of Pharmacology and Experimental Therapeutics 1983, 224:319-326.
    • (1983) The Journal of Pharmacology and Experimental Therapeutics , vol.224 , pp. 319-326
    • Risner, M.E.1    Goldberg, S.R.2
  • 103
    • 0027305458 scopus 로고
    • The neural basis of drug craving: an incentive-sensitization theory of addiction
    • Robinson T.E., Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Research Reviews 1993, 18:247-291.
    • (1993) Brain Research Reviews , vol.18 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 104
    • 0031030483 scopus 로고    scopus 로고
    • Nicotine self-administration in animals and humans: similarities and differences
    • Rose J.E., Corrigall W.A. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology 1997, 130:28-40.
    • (1997) Psychopharmacology , vol.130 , pp. 28-40
    • Rose, J.E.1    Corrigall, W.A.2
  • 105
    • 0031650073 scopus 로고    scopus 로고
    • Deprivation state but not nicotine content of the cigarette affects responding by smokers on a progressive ratio task
    • Rusted J.M., Mackee A., Williams R., Willner P. Deprivation state but not nicotine content of the cigarette affects responding by smokers on a progressive ratio task. Psychopharmacology 1998, 140:411-417.
    • (1998) Psychopharmacology , vol.140 , pp. 411-417
    • Rusted, J.M.1    Mackee, A.2    Williams, R.3    Willner, P.4
  • 107
    • 0343118812 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens
    • Schilstrom B., Nomikos G.G., Nisell M., Hertel P., Svensson T.H. N-methyl-d-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens. Neuroscience 1998, 82:781-789.
    • (1998) Neuroscience , vol.82 , pp. 781-789
    • Schilstrom, B.1    Nomikos, G.G.2    Nisell, M.3    Hertel, P.4    Svensson, T.H.5
  • 108
    • 0242289459 scopus 로고    scopus 로고
    • Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation
    • Semba J., Wakuta M., Maeda J., Suhara T. Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation. Psychoneuroendocrinology 2004, 29:215-226.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 215-226
    • Semba, J.1    Wakuta, M.2    Maeda, J.3    Suhara, T.4
  • 109
    • 0034903259 scopus 로고    scopus 로고
    • Sensitivity of nicotine-containing and de-nicotinized cigarette consumption to alternative non-drug reinforcement: a behavioral economic analysis
    • Shahan T.A., Bickel W.K., Badger G.J., Giordano L.A. Sensitivity of nicotine-containing and de-nicotinized cigarette consumption to alternative non-drug reinforcement: a behavioral economic analysis. Behavioural Pharmacology 2001, 12:277-284.
    • (2001) Behavioural Pharmacology , vol.12 , pp. 277-284
    • Shahan, T.A.1    Bickel, W.K.2    Badger, G.J.3    Giordano, L.A.4
  • 110
    • 0033986869 scopus 로고    scopus 로고
    • Comparing the reinforcing efficacy of nicotine containing and de-nicotinized cigarettes: a behavioral economic analysis
    • Shahan T.A., Bickel W.K., Madden G.J., Badger G.J. Comparing the reinforcing efficacy of nicotine containing and de-nicotinized cigarettes: a behavioral economic analysis. Psychopharmacology 1999, 147:210-216.
    • (1999) Psychopharmacology , vol.147 , pp. 210-216
    • Shahan, T.A.1    Bickel, W.K.2    Madden, G.J.3    Badger, G.J.4
  • 111
    • 0027301754 scopus 로고
    • Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: dose-dependency and desensitization
    • Sharp B.M., Matta S.G. Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: dose-dependency and desensitization. Endocrinology 1993, 133:11-19.
    • (1993) Endocrinology , vol.133 , pp. 11-19
    • Sharp, B.M.1    Matta, S.G.2
  • 112
    • 0017119485 scopus 로고
    • Smoking withdrawal symptoms in two weeks of abstinence
    • Shiffman S.M., Jarvik M.E. Smoking withdrawal symptoms in two weeks of abstinence. Psychopharmacology 1976, 50:35-39.
    • (1976) Psychopharmacology , vol.50 , pp. 35-39
    • Shiffman, S.M.1    Jarvik, M.E.2
  • 113
    • 23044514574 scopus 로고    scopus 로고
    • Increased CRF-like and NPY-like immunoreactivity in adult rats exposed to nicotine during adolescence: relation to anxiety-like and depressive-like behavior
    • Slawecki C.J., Thorsell A.K., Khoury A.E., Mathe A.A., Ehlers C.L. Increased CRF-like and NPY-like immunoreactivity in adult rats exposed to nicotine during adolescence: relation to anxiety-like and depressive-like behavior. Neuropeptides 2005, 39:369-377.
    • (2005) Neuropeptides , vol.39 , pp. 369-377
    • Slawecki, C.J.1    Thorsell, A.K.2    Khoury, A.E.3    Mathe, A.A.4    Ehlers, C.L.5
  • 114
    • 11144275200 scopus 로고    scopus 로고
    • Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats
    • Stinus L., Cador M., Zorrilla E.P., Koob G.F. Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. Neuropsychopharmacology 2005, 30:90-98.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 90-98
    • Stinus, L.1    Cador, M.2    Zorrilla, E.P.3    Koob, G.F.4
  • 115
    • 0025906706 scopus 로고
    • Behavioural pharmacology of nicotine: multiple mechanisms
    • Stolerman I.P. Behavioural pharmacology of nicotine: multiple mechanisms. British Journal of Addiction 1991, 86:533-536.
    • (1991) British Journal of Addiction , vol.86 , pp. 533-536
    • Stolerman, I.P.1
  • 116
    • 0028966054 scopus 로고
    • The scientific case that nicotine is addictive
    • (discussion 14-20)
    • Stolerman I.P., Jarvis M.J. The scientific case that nicotine is addictive. Psychopharmacology 1995, 117:2-10. (discussion 14-20).
    • (1995) Psychopharmacology , vol.117 , pp. 2-10
    • Stolerman, I.P.1    Jarvis, M.J.2
  • 117
    • 0023425001 scopus 로고
    • Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system
    • Swanson L.W., Simmons D.M., Whiting P.J., Lindstrom J. Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system. The Journal of Neuroscience 1987, 7:3334-3342.
    • (1987) The Journal of Neuroscience , vol.7 , pp. 3334-3342
    • Swanson, L.W.1    Simmons, D.M.2    Whiting, P.J.3    Lindstrom, J.4
  • 118
    • 0024393832 scopus 로고
    • Distribution of choline acetyltransferase immunopositive structures in the rat brainstem
    • Tago H., McGeer P.L., McGeer E.G., Akiyama H., Hersh L.B. Distribution of choline acetyltransferase immunopositive structures in the rat brainstem. Brain Research 1989, 495:271-297.
    • (1989) Brain Research , vol.495 , pp. 271-297
    • Tago, H.1    McGeer, P.L.2    McGeer, E.G.3    Akiyama, H.4    Hersh, L.B.5
  • 119
    • 84868194017 scopus 로고    scopus 로고
    • Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner
    • Tejeda H.A., Natividad L.A., Orfila J.E., Torres O.V., O'Dell L.E. Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner. Psychopharmacology 2012, 224:289-301.
    • (2012) Psychopharmacology , vol.224 , pp. 289-301
    • Tejeda, H.A.1    Natividad, L.A.2    Orfila, J.E.3    Torres, O.V.4    O'Dell, L.E.5
  • 120
  • 121
    • 0038174672 scopus 로고    scopus 로고
    • 9-41, reverses nicotine-induced conditioned, but not unconditioned, anxiety
    • 9-41, reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology 2003, 167:251-256.
    • (2003) Psychopharmacology , vol.167 , pp. 251-256
    • Tucci, S.1    Cheeta, S.2    Seth, P.3    File, S.E.4
  • 125
    • 0034135820 scopus 로고    scopus 로고
    • Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal
    • Watkins S.S., Koob G.F., Markou A. Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. Nicotine and Tobacco Research 2000, 2:19-37.
    • (2000) Nicotine and Tobacco Research , vol.2 , pp. 19-37
    • Watkins, S.S.1    Koob, G.F.2    Markou, A.3
  • 126
    • 0034054681 scopus 로고    scopus 로고
    • Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects
    • Watkins S.S., Stinus L., Koob G.F., Markou A. Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. The Journal of Pharmacology and Experimental Therapeutics 2000, 292:1053-1064.
    • (2000) The Journal of Pharmacology and Experimental Therapeutics , vol.292 , pp. 1053-1064
    • Watkins, S.S.1    Stinus, L.2    Koob, G.F.3    Markou, A.4
  • 127
    • 1942420850 scopus 로고    scopus 로고
    • Nicotine improves sustained attention in mice: evidence for involvement of the α7 nicotinic acetylcholine receptor
    • Young J.W., Finlayson K., Spratt C., Marston H.M., Crawford N., Kelly J.S., et al. Nicotine improves sustained attention in mice: evidence for involvement of the α7 nicotinic acetylcholine receptor. Neuropsychopharmacology 2004, 29:891-900.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 891-900
    • Young, J.W.1    Finlayson, K.2    Spratt, C.3    Marston, H.M.4    Crawford, N.5    Kelly, J.S.6
  • 128
    • 84871377513 scopus 로고    scopus 로고
    • Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test
    • Young J.W., Meves J.M., Geyer M.A. Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test. Behavioural Brain Research 2013, 240:119-133.
    • (2013) Behavioural Brain Research , vol.240 , pp. 119-133
    • Young, J.W.1    Meves, J.M.2    Geyer, M.A.3
  • 129
    • 84928397130 scopus 로고    scopus 로고
    • Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal
    • Zhao-Shea R., DeGroot S.R., Liu L., Vallaster M., Pang X., Su Q., et al. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nature Communications 2015, 6:6770.
    • (2015) Nature Communications , vol.6 , pp. 6770
    • Zhao-Shea, R.1    DeGroot, S.R.2    Liu, L.3    Vallaster, M.4    Pang, X.5    Su, Q.6


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