Nicotine vapor inhalation escalates nicotine self-administration

Addiction Biology

Volumn 19, Issue 4, 2014, Pages 587-592

  Gilpin, Nicholas W ^a   Whitaker, Annie M ^a   Baynes, Brittni ^a   Abdel, Abdelrahim Y ^a   Weil, Madelyn T ^a   George, Olivier ^b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Escalation; mecamylamine; nicotine dependence; nicotine self administration; withdrawal

Indexed keywords

MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR BLOCKING AGENT;

ADULT; AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SELF ADMINISTRATION; FLOW RATE; INHALATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOKING CESSATION; TOBACCO DEPENDENCE; VAPOR; WISTAR RAT; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; INSTRUMENTAL CONDITIONING; MOLECULAR GENETICS; PATHOPHYSIOLOGY; VOLATILIZATION; WITHDRAWAL SYNDROME;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MECAMYLAMINE; MOLECULAR SEQUENCE DATA; NICOTINE; NICOTINIC ANTAGONISTS; RATS; RATS, WISTAR; SELF ADMINISTRATION; SUBSTANCE WITHDRAWAL SYNDROME; TOBACCO USE DISORDER; VOLATILIZATION;

EID: 84904252940     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/adb.12021     Document Type: Article

References (17)

1. Cohen A, Koob GF, George O, (2012) Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence. Neuropsychopharmacology 37: 2153-2160.
2. Djordjevic MV, Stellman SD, Zang E, (2000) Doses of nicotine and lung carcinogens delivered to cigarette smokers. J Natl Cancer Inst 92: 106-111. (Pubitemid 30089866)
3. George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH, O'Dell LE, Richardson HN, Koob GF, (2007) CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats. Proc Natl Acad Sci U S A 104: 17198-17203. (Pubitemid 350211014)
4. George O, Grieder TE, Cole M, Koob GF, (2010) Exposure to chronic intermittent nicotine vapor induces nicotine dependence. Pharmacol Biochem Behav 96: 104-107.
5. Gilpin NW, Richardson HN, Cole M, Koob GF, (2008) Vapor inhalation of alcohol in rats. Curr Protoc Neurosci 44: 9.29.1-9.29.19.
6. Griffith RB, Standafer S, (1985) Simultaneous mainstream-sidestream smoke exposure systems II. The rat exposure system. Toxicology 35: 13-24. (Pubitemid 15092207)
7. Kim MJ, Fleming CB, Catalano RF, (2009) Individual and social influences on progression to daily smoking during adolescence. Pediatrics 124: 895-902.
8. Koob G, Kreek MJ, (2007) Stress, dysregulation of drug reward pathways, and the transition to drug dependence. Am J Psychiatry 164: 1149-1159. (Pubitemid 47292402)
9. Koob GF, (2008) A role for brain stress systems in addiction. Neuron 59: 11-34. (Pubitemid 351905857)
10. Malin DH, Lake JR, Newlin-Maultsby P, Roberts LK, Lanier JG, Carter VA, Cunningham JS, Wilson OB, (1992) Rodent model of nicotine abstinence syndrome. Pharmacol Biochem Behav 43: 779-784.
11. NIOSH (1977a) Backup Data Report No. S-293, Nicotine. Documentation of the NIOSH Validation Tests, Department of Health, Education, and Welfare (NIOSH) Publication No. 77-185. Prepared for NIOSH under Contract #CDC-99-74-45.
12. NIOSH (April 1977b) NIOSH manual of analytical methods, 2nd edition, Vol. 3, Method S293 DHHS (NIOSH) Publication 77-157-C.
13. O'Dell LE, Chen SA, Smith RT, Specio SE, Balster RL, Paterson NE, Markou A, Zorrilla EP, Koob GF, (2007) Extended access to nicotine self-administration leads to dependence: circadian measures, withdrawal measures, and extinction behavior in rats. J Pharmacol Exp Ther 320: 180-193. (Pubitemid 46025733)
14. O'Dell LE, Koob GF, (2007) 'Nicotine deprivation effect' in rats with intermittent 23-hour access to intravenous nicotine self-administration. Pharmacol Biochem Behav 86: 346-353.
15. Paterson NE, Markou A, (2004) Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats. Psychopharmacology (Berl) 173: 64-72. (Pubitemid 38591148)
16. Rose JE, Mukhin AG, Lokitz SJ, Turkington TG, Herskovic J, Behm FM, Garg S, Garg PK, (2010) Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine. Proc Natl Acad Sci U S A 107: 5190-5195.
17. Xie JP, Sun SH, Wang HY, Zong YL, Nie C, Guo YL, (2006) Determination of nicotine in mainstream smoke on the single puff level by liquid-phase microextraction coupled to matrix-assisted laser desorption/ionization Fourier transform mass spectrometry. Rapid Commun Mass Spectrom 20: 2573-2578. (Pubitemid 44320212)