Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner

Psychopharmacology

Volumn 224, Issue 2, 2012, Pages 289-301

  Tejeda, Hugo A ^a,b   Natividad, Luis A ^a   Orfila, James E ^a   Torres, Oscar V ^a   O'Dell, Laura E ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Adolescent; Anxiety; Conditioned place aversion; Development; Dopamine; Elevated plus maze; Nicotinic mesolimbic microdialysis nucleus accumbens

Indexed keywords

DOPAMINE; KAPPA OPIATE RECEPTOR; NICOTINE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; AVERSION; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; MALE; MAZE TEST; MESOLIMBIC DOPAMINERGIC SYSTEM; MICRODIALYSIS; NEUROCHEMISTRY; NEUROMODULATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; TOBACCO DEPENDENCE; WITHDRAWAL SYNDROME;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; AGING; ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NALTREXONE; NICOTINE; NUCLEUS ACCUMBENS; RATS; RATS, WISTAR; RECEPTORS, OPIOID, KAPPA; SUBSTANCE WITHDRAWAL SYNDROME; TOBACCO USE DISORDER;

EID: 84868194017     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2752-7     Document Type: Article

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