Nicotine self-administration in animals as a dependence model

Nicotine and Tobacco Research

Volumn 1, Issue 1, 1999, Pages 11-20

  Corrigall, William A ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; OPIATE RECEPTOR;

ADDICTION; ANIMAL; DISEASE MODEL; DRUG EFFECT; DRUG SELF ADMINISTRATION; LIMBIC SYSTEM; METABOLISM; PATHOPHYSIOLOGY; REPRODUCIBILITY; REVIEW; TOBACCO DEPENDENCE; VENTRAL TEGMENTUM;

ANIMALS; BEHAVIOR, ADDICTIVE; DISEASE MODELS, ANIMAL; LIMBIC SYSTEM; NICOTINE; RECEPTORS, OPIOID; REPRODUCIBILITY OF RESULTS; SELF ADMINISTRATION; TOBACCO USE DISORDER; VENTRAL TEGMENTAL AREA;

EID: 0033085846     PISSN: 14622203     EISSN: None     Source Type: Journal    
DOI: 10.1080/14622299050011121     Document Type: Review

References (104)

1. APA. 1994. Diagnostic and Statistical Manual of Mental Disorders, DSM-IV™. Washington, DC: American Psychiatric Association.
2. Bals-Kubik R, Ableitner A, Herz A, Shippenberg TS. 1993. Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats. Journal of Pharmacology and Experimental Therapeutics 264: 489-495.
3. Bechara A, van der Kooy D. 1989. The tegmental pedunculopontine nucleus: a brain-stem output of the limbic system critical for the conditioned place preferences produced by morphine and amphetamine. Journal of Neuroscience 9:3400-3409.
4. Bechara A, van der Kooy D. 1992. A single brainstem substrate mediates the motivational effects of both opiates and food in non-deprived rats but not in deprived rats. Behavioural Neuroscience 106:351-363.
5. Bechara A, Harrington F, Nader K, van der Kooy D. 1992. Neurobiology of motivation: double dissociation of two motivational mechanisms mediating opiate reward in drug-naive versus drug-dependent animals. Behavioural Neuroscience 106:798-807.
6. Benowitz NL, Jacob P, III. 1990. Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking. Journal of Pharmacology and Experimental Therapeutics 254:1000-1005.
7. Benwell MEM, Balfour DJK. 1992. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British Journal of Pharmacology 105:849-856.
8. Benwell MEM, Balfour DJK, Birrell CE. 1995. Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine. British Journal of Pharmacology 114:454-460.
9. Benwell MEM, Balfour DJK, Lucchi HM. 1993. Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine. Psychopharmacology 112:467-474.
10. Blaha CD, Allen LF, Das S, Inglis WL, Latimer MP, Vincent SR, Winn P. 1996. Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats. Journal of Neuroscience 16:714-722.
11. Bolam JP, Francis CM, Henderson Z. 1991. Cholinergic input to dopaminergic neurons in the substantia nigra: a double immunocytochemical study. Neuroscience 41:483-494.
12. Calabresi P, Lacey MG, North RA. 1989. Nicotinic excitation of rat ventral tegmental neuronesin vitro studied by intracellular recording. British Journal of Pharmacology 98:135-140.
13. Chiamulera C, Borgo C, Falchetto S, Valerio E, Tessari M. 1996. Nicotine reinstatement of nicotine self-administration after long-term extinction. Psychopharmacology 127:102-107.
14. Clarke PBS, Pert A. 1985. Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons. Brain Research 348:355-358.
15. Clarke PBS, Fu DS, Jakubovic A, Fibiger HC. 1988. Evidence that mesolimbic dopaminergic activation underlies the locomotor action of nicotine in rats. Journal of Pharmacology and Experimental Therapeutics 246:701-708.
16. Collins RJ, Weeks JR, Cooper MM, Good PI, Russell RR. 1984. Prediction of abuse liability of drugs using i.v. self-administration by rats. Psychopharmacology 82:6-13.
17. Corrigall WA. 1992. A rodent model for nicotine self-administration. In: Boulton A, Baker G, Wu P, eds. Neuromethods. Clifton, NJ: Humana Press, pp. 315-344.
18. Corrigall WA, Coen KM. 1989. Nicotine maintains robust self-administration in rats on a limited-access schedule. Psychopharmacology 99:473-478.
19. Corrigall WA, Coen KM. 1991a. Opiate antagonists reduce cocaine but not nicotine self-administration. Psychopharmacology 104:167-170.
20. Corrigall WA, Coen KM. 1991b. Selective dopamine anatgonists reduce nicotine self-administration. Psychopharmacology 104:171-176.
21. Corrigall WA, Coen KM, Adamson KL. 1994. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Research 653:278-284.
22. Corrigall WA, Coen KM, Adamson KL, Chow BLC. 1999. The mu opioid agonist DAMGO alters the intravenous self-administration of cocaine in rats: mechanisms in the ventral tegmental area. Psychopharmacology, in press.
23. Corrigall WA, Franklin KBJ, Coen KM, Clarke PBS. 1992. The mesolimbic dopamine system is implicated in the reinforcing effects of nicotine. Psychopharmacology 107:285-289.
24. Dawe S, Gerada C, Russell MAH, Gray JA. 1995. Nicotine intake in smokers increases following a single dose of haloperidol. Psychopharmacology 117:110-116.
25. Deutsch AY, Holliday J, Roth RH, Chun LLY, Hawrot E. 1987. Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain. Proceedings of the National Academy of Sciences, USA 84:8697-8701.
26. Devine DP, Wise RA. 1994. Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. Journal of Neuroscience 14:1978-1984.
27. Devine DP, Leone P, Pocock D, Wise RA. 1993. Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: In vivo microdialysis studies. Journal of Pharmacology and Experimental Therapeutics 266:1236-1246.
28. DHHS. 1988. The Health Consequences of Smoking: Nicotine Addiction. A Report of the Surgeon General. Rockville MD: US Department of Health and Human Services.
29. Di Chiara G, Acquas E, Carboni E. 1991. Role of mesolimbic dopamine in the motivational effects of drugs: brain dialysis and place preference studies. In: Willner P, Scheel-Kruger J, eds. The Mesolimbic Dopamine System: From Motivation to Action. New York, NY: John Wiley & Sons, pp. 367-384.
30. Dilts RP, Kalivas PW. 1989. Autoradiographic localization of mu-opioid and neurotensin receptors within the mesolimbic dopamine system. Brain Research 488:311-327.
31. Donny EC, Caggiula AR, Knopf S, Brown C. 1995. Nicotine self-administration in rats. Psychopharmacology 122:390-394.
32. Dunbar JS, Hitchcock K, Latimer M, Rugg EL, Ward N, Winn P. 1992. Excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. II. Examination of eating and drinking, rotation, and reaching and grasping following unilateral ibotenate or quinolinate lesions. Brain Research 589:194-206.
33. Foulds J, Stapleton J, Feyerabend C, Vesey C, Jarvis M, Russell MAH. 1992. Effect of transdermal nicotine patches on cigarette smoking: a double blind crossover study. Psychopharmacology 106:421-427.
34. German DC, Speciale SG, Manaye KF, Sadeq M. 1993. Opioid receptors in midbrain dopaminergic regions of the rat. I. Mu receptor autoradiography. Journal of Neural Transmission 91:39-52.
35. Glowa JR, Fantegrossi WE. 1997. Effects of dopaminergic drugs on food- and cocaine-maintained responding. IV: continuous cocaine infusions. Drug and Alcohol Dependence 45:71-79.
36. Goldberg SR, Henningfield JE. 1997. A parametric study of intravenous nicotine self-administration by humans and squirrel monkeys. NIDA Research Monograph 174, 65.
37. Goldberg SR, Spealman RD, Goldberg DM. 1981. Persistent behavior at high rates maintained by intravenous self-administration of nicotine. Science 214:573-575.
38. Grady S, Marks MJ, Wonnacott S, Collins AC. 1992. Characterization of nicotinic receptor-mediated [3H]dopamine release from synaptosomes prepared from mouse striatum. Journal of Neurochemistry 59:848-856.
39. Griffiths RR, Bigelow GE, Henningfield JE. 1980. Similarities in animal and human drug taking behavior. In: Mello NK, ed. Advances in Substance Abuse. Greenwich CT: JAI Press, pp. 1-90.
40. Griffiths RR, Brady JV, Bradford LD. 1979. Predicting the abuse liability of drugs with animal drug self-administration procedures: psychomotor stimulants and hallucinogens. In: Thompson T, Dews PB, eds. Advances in Behavioral Pharmacology. Volume 2. New York: Academic Press, pp. 163-208.
41. Gysling K, Wang RY. 1983. Morphine-induced activation of A10 dopamine neurons in the rat. Brain Research 277:119-127.
42. Henningfield JE, Cohen C, Slade JD. 1991. Is nicotine more addictive than cocaine? British Journal of Addiction 86:565-569.
43. Henningfield JE, Miyasato K, Jasinski DR. 1983. Cigarette smokers self-administer intravenous nicotine. Pharmacology Biochemistry and Behavior 19:887-890.
44. Imperato A, Mulas A, Di Chiara G. 1986. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats. European Journal of Pharmacology 132:337-338.
45. Jenck F, Bozarth M, Wise RA. 1988. Contraversive circling induced by ventral tegmental microinjections of moderate doses of morphine and [D-Pen2, D-Pen5]enkephalin. Brain Research 450:382-386.
46. Johanson CE, Schuster CR. 1981. Animal models of drug self-administration. In: Mello NK, ed. Advances in substance abuse. Greenwich CT: JAI Press, pp. 219-297.
47. Johnson SW, North RA. 1992. Opioids excite dopamine neurons by hyperpolarization of local interneurons. Journal of Neuroscience 12:483-488.
48. Joyce EM, Iversen SD. 1979. The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat. Neuroscience Letters 14:207-212.
49. Kalivas PW. 1993. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Research Reviews 18:75-113.
50. Kalivas PW, Duffy P. 1990. Effect of acute and daily neurotensin and enkephalin treatments on extracellular dopamine in the nucleus accumbens. Journal of Neuroscience 10:2940-2949.
51. Katner SN, McBride WJ, Lumeng L, Li T-K, Murphy JM. 1997. Alcohol intake of P rats is regulated by muscarinic receptors in the pedunculopontine nucleus and VTA. Pharmacology Biochemistry and Behavior 58:497-504.
52. Klitenick MA, DeWitte P, Kalivas PW. 1992. Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. Journal of Neuroscience 12:2623-2632.
53. Klitenick MA, Wirtshafter D. 1995. Behavioral and neurochemical effects of opioids in the paramedian midbrain tegmentum including the median raphe nucleus and ventral tegmental area. Journal of Pharmacology and Experimental Therapeutics 273:327-336.
54. Koob GF. 1992. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends in Pharmacological Science 13:177-184.
55. Kozlowski LT, Herman C P. 1984. The interaction of psychosocial and biological determinants of tobacco use: more on the boundary model. Journal of Applied Social Psychology 14:244-256.
56. Latimer LG, Duffy P, Kalivas PW. 1987. Mu opioid receptor involvement in enkcphalin activation of dopamine neurons in the ventral tegmental area. Journal of Pharmacology and Experimental Therapeutics 241:328-337.
57. Le Novère N, Zoli M, Changeux J-P. 1996. Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. European Journal of Neuroscience 8:2428-2439.
58. Lucchesi BR, Schuster CR, Emley GS. 1967. The role of nicotine as a determinant of cigarette smoking frequency in man with observations of certain cardiovascular effects associated with the tobacco alkaloid. Clinical Pharmacology and Therapeutics 8:789-796.
59. Malin DH, Lake JR, Carter VA, Cunningham JS, Wilson OB. 1993. Naloxone precipitates nicotine abstinence syndrome in the rat. Psychopharmacology 112:339-342.
60. Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ. 1987. Autoradiographic differentiation of mu, delta and kappa opioid receptors in rat forebrain and midbrain. Journal of Neuroscience 7:2445-2464.
61. Matthews RT, German DC. 1984. Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine. Neuroscience 11:617-625.
62. McEvoy JP, Freudenreich O, Levin ED, Rose JE. 1995. Haloperidol increases smoking in patients with schizophrenia. Psychopharmacology 119:124-126.
63. McGehee DS, Heath MJS, Gelber S, Devay P, Role LW. 1995. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269:1692-1696.
64. Mifsud J, Hernandez L, Hoebel BG. 1989. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain Research 478:365-367.
65. Mogenson GJ, Brudzynski SM, Wu M, Yang CR, Yim CCY. 1993. From motivation to action: a review of dopaminergic regulation of limbic-nucleus accumbens-ventral pallidum- pedunculopontine nucleus circuitries involved in limbic-motor integration. In: Kalivas PW, Barnes CD, eds. Limbic Motor Circuits and Neuropsychiatry. Boca Raton FL: CRC Press, Inc., pp. 193-236.
66. Nisell M, Nomikos GG, Svensson TH. 1994. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area. Synapse 16:36-44.
67. Oakman SA, Faris PL, Kerr PE, Cozzari C, Hartman BK. 1995. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. Journal of Neuroscience 15:5859-5869.
68. Olmstead MC, Franklin KBJ. 1993. Effects of pedunculopontine tegmental nucleus lesions on morphine-induced conditioned place preference and analcesia in the formalin test. Neuroscience 57:411-418.
69. Olmstead MC, Franklin KBJ. 1994a. Lesions of the pedunculopontine tegmental nucleus abolish, catalepsy and locomotor depression induced by morphine. Brain Research 662:134-140.
70. Olmstead MC, Franklin KBJ. 1994b. Lesions of the pedunculopontine tegmental nucleus block drug-induced reinforcement but not amphetamine-induced locomotion. Brain Research 638:29-35.
71. Olmstead MC, Munn EM, Franklin KBJ, Wise RA. 1998. Effects of pedunculopontine tegmental nucleus lesions on responding for intravenous heroin under different schedules of reinforcement. Journal of Neuroscience 18:in press.
72. Orr-Utreger A, Goldner FM, Saeki M, Lorenzo I, Golberg L, De Biasi M, Dani JA, Patrick JW, Beaud et al. 1997. Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. Journal of Neuroscience 17:9165-9171.
73. Pagliusi SR, Tessari M, DeVevey S, Chiamulera C, Pich EM. 1996. The reinforcing properties of nicotine are associated with a specific patterning of c-fos expression in the rat brain. European Journal of Neuroscience 8:2247-2256.
74. Perkins KA, Grobe JE, Stiller RL, Fonte C, Goettler JE. 1992. Nasal spray nicotine replacement suppresses cigarette smoking desire and behavior. Clinical Pharmacology and Therapeutics 52:627-634.
75. Phillips AG, Pfaus JG, Blaha CD. 1991. Dopamine and motivated behavior: insights provided by in vivo analyses. In: Willner P, Scheel-Kruger J, eds. The Mesolimbic Dopamine System: From Motivation to Action. New York NY: John Wiley & Sons, pp. 199-224.
76. Picciotto MR, Zoli M, Lena C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Pich EM, Brulet P, Changeux JP. 1995. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 374:65-67.
77. Picciotto MR, Zoli M, Rimondini R, Lena C, Marubio LM, Merlo Pich E, Fuxe K, Changeux J-P. 1998. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature 391:173-177.
78. Pich EM, Pagliusi SR, Tessari M, Talabot-Ayer D, Hooft van Huijsduijnen R, Chiamulera C. (1997). Common neural substrates for the addictive properties of nicotine and cocaine. Science 275:83-86.
79. Pidoplichko VI, DeBiasi M, Williams JT, Dani JA. 1997. Nicotine activates and desensitizes midbrain dopamine neurons. Nature 390:401-404.
80. Pomerleau OF. 1998. Endogenous opioids and smoking: a review of progress and problems. Psychoneuroendocrinology 23:115-130.
81. Pomerleau OF, Fertig JB, Shanahan SO. 1983. Nicotine dependence in cigarette smoking: an empirically-based, multivariate model. Pharmacology Biochemistry & Behavior 19:291-299.
82. Pontieri FE, Tanda G, Orzi F, Di Chiara G. 1996. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 382:255-257.
83. Risner ME, Goldberg SR. 1983. A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion. Journal of Pharmacology and Experimental Therapeutics 224:319-326.
84. Robinson TE, Berridge KC. 1993. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Research Reviews 18:247-291.
85. Rose JE, Corrigall WA. 1997. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology 130:28-40.
86. Rose JE, Westman EC, Behm FM. 1994. Nicotine/mecamylamine combination for smoking cessation. Drug Development Research 38:243-256.
87. Rothman RB, Glowa JR. 1995. A review of the effects of dopaminergic agents on humans, animals and drug-seeking behavior, and its implications for medication development. Molecular Neurobiology 11:1-19.
88. Royal Society of Canada. 1989. Tobacco, Nicotine, and Addiction. A Committee Report Prepared at the Request of the Royal Society of Canada. Canada: Health Protection Branch, pp. 1-6.
89. Russell MAH. 1987. Nicotine intake and its regulation by smokers. In: Martin WR, Van Loon GR, Iwamoto ET, Davis L, eds. Tobacco Smoking and Nicotine. New York: Plenum Press, pp. 25-50.
90. Sannerud CA, Prada J, Goldberg DM, Goldberg SR. 1994. The effects of sertraline on nicotine self-administration and food-maintained responding in squirrel monkeys. European Journal of Pharmacology 271:461-469.
91. Sargent PB. 1993. The diversity of neuronal nicotinic acetylcholine receptors. Annual Review of Neuroscience 16:403-443.
92. Shaham Y, Adamson KL, Grocki S, Corrigall WA. 1997. Reinstatement and spontaneous recovery of nicotine seeking in rats. Psychopharmacology 130:396-403.
93. Shoaib M, Schindler CW, Goldberg SR. 1997. Nicotine self-administration in rats: strain and nicotine pre-exposure effects on acquisition. Psychopharmacology 129:35-43.
94. Spanagel R, Herz A, Shippenberg TS. 1992. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proceedings of the National Academy of Sciences, USA 89:2046-2050.
95. Swanson LW, Simmons DM, Whiting PJ, Lindstrom J. 1987. Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system. Journal of Neuroscience 7:3334-3342.
96. Tessari M, Valerio E, Chiamulera C, Beardsley PM. 1995. Nicotine reinforcement in rats with histories of cocaine self-administration. Psychopharmacology 121:282-283.
97. Valentine JD, Hokanson JS, Matta SG, Sharp BM. 1997. Self-administration in rats allowed unlimited access to nicotine. Psychopharmacology 133:300-304.
98. Vezina P, Kalivas PW, Stewart J. 1987. Sensitization occurs to the locomotor effects of morphine and the specific mu opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens. Brain Research 417:51-58.
99. Wada E, Wada K, Boulter J, Deneris E, Heinemann S, Patrick J, Swanson LW. 1989. Distribution of alpha2, alpha3, alpha4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. Journal of Comparative Neurology 284:314-335.
100. Wise RA. 1996. Neurobiology of addiction. Current Opinion in Neurobiology 6:243-251.
101. Witkin JM. 1994. Pharmacotherapy of cocaine abuse: preclinical development. Neuroscience and Biobehavioral Reviews 18:121-142.
102. Yeomans J, Baptista M. 1997. Both nicotinic and muscarinic receptors in ventral tegmental area contribute to brain-stimulation reward. Pharmacology Biochemistry and Behavior 57:915-921.
103. Yeomans JS. 1995. Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia. Neuropsychopharmacology 12:3-16.
104. Yeomans JS, Mathur A, Tampakeras M. 1993. Rewarding brain stimulation: role of tegmental cholinergic neurons that activate dopamine neurons. Behavioral Neuroscience 107:1077-1087.