-
1
-
-
84875895887
-
Isolation and differentiation of stromal vascular cells to beige/brite cells
-
Aune UL, Ruiz L, Kajimura S (2013) Isolation and differentiation of stromal vascular cells to beige/brite cells. J Vis Exp 73: 50191
-
(2013)
J Vis Exp
, vol.73
, pp. 50191
-
-
Aune, U.L.1
Ruiz, L.2
Kajimura, S.3
-
2
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
-
Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J, Daugaard JR, Lloberas J, Camps M, Zierath JR, Rabasa-Lhoret R, Wallberg-Henriksson H, Laville M, Palacin M, Vidal H, Rivera F, Brand M, Zorzano A (2003) Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 278: 17190–17197
-
(2003)
J Biol Chem
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
Pich, S.2
Soriano, F.X.3
Vega, N.4
Baumgartner, B.5
Oriola, J.6
Daugaard, J.R.7
Lloberas, J.8
Camps, M.9
Zierath, J.R.10
Rabasa-Lhoret, R.11
Wallberg-Henriksson, H.12
Laville, M.13
Palacin, M.14
Vidal, H.15
Rivera, F.16
Brand, M.17
Zorzano, A.18
-
3
-
-
24144462451
-
Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6
-
Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J, Laville M, Guillet C, Boirie Y, Wallberg-Henriksson H, Manco M, Calvani M, Castagneto M, Palacin M, Mingrone G, Zierath JR, Vidal H, Zorzano A (2005) Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes 54: 2685–2693
-
(2005)
Diabetes
, vol.54
, pp. 2685-2693
-
-
Bach, D.1
Naon, D.2
Pich, S.3
Soriano, F.X.4
Vega, N.5
Rieusset, J.6
Laville, M.7
Guillet, C.8
Boirie, Y.9
Wallberg-Henriksson, H.10
Manco, M.11
Calvani, M.12
Castagneto, M.13
Palacin, M.14
Mingrone, G.15
Zierath, J.R.16
Vidal, H.17
Zorzano, A.18
-
4
-
-
79953752384
-
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
-
Bai P, Canto C, Oudart H, Brunyanszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J (2011) PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab 13: 461–468
-
(2011)
Cell Metab
, vol.13
, pp. 461-468
-
-
Bai, P.1
Canto, C.2
Oudart, H.3
Brunyanszki, A.4
Cen, Y.5
Thomas, C.6
Yamamoto, H.7
Huber, A.8
Kiss, B.9
Houtkooper, R.H.10
Schoonjans, K.11
Schreiber, V.12
Sauve, A.A.13
Menissier-de Murcia, J.14
Auwerx, J.15
-
5
-
-
66349128492
-
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
-
Bickel PE, Tansey JT, Welte MA (2009) PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores. Biochim Biophys Acta 1791: 419–440
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 419-440
-
-
Bickel, P.E.1
Tansey, J.T.2
Welte, M.A.3
-
6
-
-
0020569403
-
Movement of lipolytic products to mitochondria in brown adipose tissue of young rats: an electron microscope study
-
Blanchette-Mackie EJ, Scow RO (1983) Movement of lipolytic products to mitochondria in brown adipose tissue of young rats: an electron microscope study. J Lipid Res 24: 229–244
-
(1983)
J Lipid Res
, vol.24
, pp. 229-244
-
-
Blanchette-Mackie, E.J.1
Scow, R.O.2
-
7
-
-
84857632171
-
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria
-
Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK (2012) The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem Cell Biol 137: 205–216
-
(2012)
Histochem Cell Biol
, vol.137
, pp. 205-216
-
-
Bosma, M.1
Minnaard, R.2
Sparks, L.M.3
Schaart, G.4
Losen, M.5
de Baets, M.H.6
Duimel, H.7
Kersten, S.8
Bickel, P.E.9
Schrauwen, P.10
Hesselink, M.K.11
-
8
-
-
84921829213
-
SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function
-
Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2015) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4: 118–131
-
(2015)
Mol Metab
, vol.4
, pp. 118-131
-
-
Boutant, M.1
Joffraud, M.2
Kulkarni, S.S.3
Garcia-Casarrubios, E.4
Garcia-Roves, P.M.5
Ratajczak, J.6
Fernandez-Marcos, P.J.7
Valverde, A.M.8
Serrano, M.9
Canto, C.10
-
9
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito OM, Scorrano L (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456: 605–610
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
10
-
-
78651313711
-
Nonshivering thermogenesis and its adequate measurement in metabolic studies
-
Cannon B, Nedergaard J (2011) Nonshivering thermogenesis and its adequate measurement in metabolic studies. J Exp Biol 214: 242–253
-
(2011)
J Exp Biol
, vol.214
, pp. 242-253
-
-
Cannon, B.1
Nedergaard, J.2
-
11
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160: 189–200
-
(2003)
J Cell Biol
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
12
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
Chen H, McCaffery JM, Chan DC (2007) Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell 130: 548–562
-
(2007)
Cell
, vol.130
, pp. 548-562
-
-
Chen, H.1
McCaffery, J.M.2
Chan, D.C.3
-
13
-
-
84867003433
-
Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study
-
Cosson P, Marchetti A, Ravazzola M, Orci L (2012) Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study. PLoS One 7: e46293
-
(2012)
PLoS One
, vol.7
-
-
Cosson, P.1
Marchetti, A.2
Ravazzola, M.3
Orci, L.4
-
14
-
-
0014830814
-
Structure-function relationships in the adipose cell. I. Ultrastructure of the isolated adipose cell
-
Cushman SW (1970) Structure-function relationships in the adipose cell. I. Ultrastructure of the isolated adipose cell. J Cell Biol 46: 326–341
-
(1970)
J Cell Biol
, vol.46
, pp. 326-341
-
-
Cushman, S.W.1
-
15
-
-
84884877043
-
Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity
-
Dietrich MO, Liu ZW, Horvath TL (2013) Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity. Cell 155: 188–199
-
(2013)
Cell
, vol.155
, pp. 188-199
-
-
Dietrich, M.O.1
Liu, Z.W.2
Horvath, T.L.3
-
16
-
-
84994824112
-
Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue
-
Duteil D, Tosic M, Lausecker F, Nenseth HZ, Muller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Bruning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schule R (2016) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17: 1008–1021
-
(2016)
Cell Rep
, vol.17
, pp. 1008-1021
-
-
Duteil, D.1
Tosic, M.2
Lausecker, F.3
Nenseth, H.Z.4
Muller, J.M.5
Urban, S.6
Willmann, D.7
Petroll, K.8
Messaddeq, N.9
Arrigoni, L.10
Manke, T.11
Kornfeld, J.W.12
Bruning, J.C.13
Zagoriy, V.14
Meret, M.15
Dengjel, J.16
Kanouni, T.17
Schule, R.18
-
17
-
-
79952155359
-
Transcriptional control of adipose lipid handling by IRF4
-
Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED (2011) Transcriptional control of adipose lipid handling by IRF4. Cell Metab 13: 249–259
-
(2011)
Cell Metab
, vol.13
, pp. 249-259
-
-
Eguchi, J.1
Wang, X.2
Yu, S.3
Kershaw, E.E.4
Chiu, P.C.5
Dushay, J.6
Estall, J.L.7
Klein, U.8
Maratos-Flier, E.9
Rosen, E.D.10
-
18
-
-
84958666424
-
Supramolecular organization of respiratory complexes
-
Enriquez JA (2016) Supramolecular organization of respiratory complexes. Annu Rev Physiol 78: 533–561
-
(2016)
Annu Rev Physiol
, vol.78
, pp. 533-561
-
-
Enriquez, J.A.1
-
19
-
-
84928600551
-
Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling
-
Filadi R, Greotti E, Turacchio G, Luini A, Pozzan T, Pizzo P (2015) Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling. Proc Natl Acad Sci USA 112: E2174–E2181
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E2174-E2181
-
-
Filadi, R.1
Greotti, E.2
Turacchio, G.3
Luini, A.4
Pozzan, T.5
Pizzo, P.6
-
20
-
-
34347236921
-
Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts
-
Frezza C, Cipolat S, Scorrano L (2007) Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts. Nat Protoc 2: 287–295
-
(2007)
Nat Protoc
, vol.2
, pp. 287-295
-
-
Frezza, C.1
Cipolat, S.2
Scorrano, L.3
-
21
-
-
43049117153
-
Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential
-
Guillery O, Malka F, Landes T, Guillou E, Blackstone C, Lombes A, Belenguer P, Arnoult D, Rojo M (2008) Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential. Biol Cell 100: 315–325
-
(2008)
Biol Cell
, vol.100
, pp. 315-325
-
-
Guillery, O.1
Malka, F.2
Landes, T.3
Guillou, E.4
Blackstone, C.5
Lombes, A.6
Belenguer, P.7
Arnoult, D.8
Rojo, M.9
-
22
-
-
77649244994
-
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity
-
Hernandez-Alvarez MI, Thabit H, Burns N, Shah S, Brema I, Hatunic M, Finucane F, Liesa M, Chiellini C, Naon D, Zorzano A, Nolan JJ (2010) Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity. Diabetes Care 33: 645–651
-
(2010)
Diabetes Care
, vol.33
, pp. 645-651
-
-
Hernandez-Alvarez, M.I.1
Thabit, H.2
Burns, N.3
Shah, S.4
Brema, I.5
Hatunic, M.6
Finucane, F.7
Liesa, M.8
Chiellini, C.9
Naon, D.10
Zorzano, A.11
Nolan, J.J.12
-
23
-
-
69249218992
-
Lipid droplets interact with mitochondria using SNAP23
-
Jagerstrom S, Polesie S, Wickstrom Y, Johansson BR, Schroder HD, Hojlund K, Bostrom P (2009) Lipid droplets interact with mitochondria using SNAP23. Cell Biol Int 33: 934–940
-
(2009)
Cell Biol Int
, vol.33
, pp. 934-940
-
-
Jagerstrom, S.1
Polesie, S.2
Wickstrom, Y.3
Johansson, B.R.4
Schroder, H.D.5
Hojlund, K.6
Bostrom, P.7
-
24
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51: 2944–2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
25
-
-
84872057896
-
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
-
Kim KH, Jeong YT, Oh H, Kim SH, Cho JM, Kim YN, Kim SS, Kim do H, Hur KY, Kim HK, Ko T, Han J, Kim HL, Kim J, Back SH, Komatsu M, Chen H, Chan DC, Konishi M, Itoh N et al (2013) Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med 19: 83–92
-
(2013)
Nat Med
, vol.19
, pp. 83-92
-
-
Kim, K.H.1
Jeong, Y.T.2
Oh, H.3
Kim, S.H.4
Cho, J.M.5
Kim, Y.N.6
Kim, S.S.7
Kim do, H.8
Hur, K.Y.9
Kim, H.K.10
Ko, T.11
Han, J.12
Kim, H.L.13
Kim, J.14
Back, S.H.15
Komatsu, M.16
Chen, H.17
Chan, D.C.18
Konishi, M.19
Itoh, N.20
more..
-
26
-
-
85000504307
-
Mfn1 deficiency in the liver protects against diet-induced insulin resistance and enhances the hypoglycemic effect of metformin
-
Kulkarni SS, Joffraud M, Boutant M, Ratajczak J, Gao AW, Maclachlan C, Hernandez-Alvarez MI, Raymond F, Metairon S, Descombes P, Houtkooper RH, Zorzano A, Canto C (2016) Mfn1 deficiency in the liver protects against diet-induced insulin resistance and enhances the hypoglycemic effect of metformin. Diabetes 65: 3552–3560
-
(2016)
Diabetes
, vol.65
, pp. 3552-3560
-
-
Kulkarni, S.S.1
Joffraud, M.2
Boutant, M.3
Ratajczak, J.4
Gao, A.W.5
Maclachlan, C.6
Hernandez-Alvarez, M.I.7
Raymond, F.8
Metairon, S.9
Descombes, P.10
Houtkooper, R.H.11
Zorzano, A.12
Canto, C.13
-
27
-
-
84920948052
-
Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation
-
Lee J, Ellis JM, Wolfgang MJ (2015) Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation. Cell Rep 10: 266–279
-
(2015)
Cell Rep
, vol.10
, pp. 266-279
-
-
Lee, J.1
Ellis, J.M.2
Wolfgang, M.J.3
-
28
-
-
84875906572
-
Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure
-
Liesa M, Shirihai OS (2013) Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab 17: 491–506
-
(2013)
Cell Metab
, vol.17
, pp. 491-506
-
-
Liesa, M.1
Shirihai, O.S.2
-
30
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306: 457–461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
31
-
-
84255192658
-
Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
-
Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF Jr, Stanley WC, Walsh K (2012) Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol 302: H167–H179
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
, pp. H167-H179
-
-
Papanicolaou, K.N.1
Ngoh, G.A.2
Dabkowski, E.R.3
O'Connell, K.A.4
Ribeiro, R.F.5
Stanley, W.C.6
Walsh, K.7
-
32
-
-
57749100271
-
Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells
-
Park KS, Wiederkehr A, Kirkpatrick C, Mattenberger Y, Martinou JC, Marchetti P, Demaurex N, Wollheim CB (2008) Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells. J Biol Chem 283: 33347–33356
-
(2008)
J Biol Chem
, vol.283
, pp. 33347-33356
-
-
Park, K.S.1
Wiederkehr, A.2
Kirkpatrick, C.3
Mattenberger, Y.4
Martinou, J.C.5
Marchetti, P.6
Demaurex, N.7
Wollheim, C.B.8
-
34
-
-
20444461625
-
The charcot-marie-tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
-
Pich S, Bach D, Briones P, Liesa M, Camps M, Testar X, Palacin M, Zorzano A (2005) The charcot-marie-tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum Mol Genet 14: 1405–1415
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1405-1415
-
-
Pich, S.1
Bach, D.2
Briones, P.3
Liesa, M.4
Camps, M.5
Testar, X.6
Palacin, M.7
Zorzano, A.8
-
35
-
-
80455143668
-
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis
-
Pidoux G, Witczak O, Jarnaess E, Myrvold L, Urlaub H, Stokka AJ, Kuntziger T, Tasken K (2011) Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. EMBO J 30: 4371–4386
-
(2011)
EMBO J
, vol.30
, pp. 4371-4386
-
-
Pidoux, G.1
Witczak, O.2
Jarnaess, E.3
Myrvold, L.4
Urlaub, H.5
Stokka, A.J.6
Kuntziger, T.7
Tasken, K.8
-
36
-
-
80053062569
-
Interactomic study on interaction between lipid droplets and mitochondria
-
Pu J, Ha CW, Zhang S, Jung JP, Huh WK, Liu P (2011) Interactomic study on interaction between lipid droplets and mitochondria. Protein Cell 2: 487–496
-
(2011)
Protein Cell
, vol.2
, pp. 487-496
-
-
Pu, J.1
Ha, C.W.2
Zhang, S.3
Jung, J.P.4
Huh, W.K.5
Liu, P.6
-
37
-
-
84898599881
-
Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice
-
Qiao L, Yoo H, Bosco C, Lee B, Feng GS, Schaack J, Chi NW, Shao J (2014) Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice. Diabetologia 57: 1027–1036
-
(2014)
Diabetologia
, vol.57
, pp. 1027-1036
-
-
Qiao, L.1
Yoo, H.2
Bosco, C.3
Lee, B.4
Feng, G.S.5
Schaack, J.6
Chi, N.W.7
Shao, J.8
-
38
-
-
84925324049
-
Fatty acid trafficking in starved cells: regulation by lipid droplet lipolysis, autophagy, and mitochondrial fusion dynamics
-
Rambold AS, Cohen S, Lippincott-Schwartz J (2015) Fatty acid trafficking in starved cells: regulation by lipid droplet lipolysis, autophagy, and mitochondrial fusion dynamics. Dev Cell 32: 678–692
-
(2015)
Dev Cell
, vol.32
, pp. 678-692
-
-
Rambold, A.S.1
Cohen, S.2
Lippincott-Schwartz, J.3
-
39
-
-
84923384071
-
Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb
-
Ramos SV, MacPherson RE, Turnbull PC, Bott KN, LeBlanc P, Ward WE, Peters SJ (2014) Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb. Physiol Rep 2: e12154
-
(2014)
Physiol Rep
, vol.2
-
-
Ramos, S.V.1
MacPherson, R.E.2
Turnbull, P.C.3
Bott, K.N.4
LeBlanc, P.5
Ward, W.E.6
Peters, S.J.7
-
40
-
-
33746927077
-
Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt
-
Robey RB, Hay N (2006) Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt. Oncogene 25: 4683–4696
-
(2006)
Oncogene
, vol.25
, pp. 4683-4696
-
-
Robey, R.B.1
Hay, N.2
-
41
-
-
84884823792
-
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance
-
Schneeberger M, Dietrich MO, Sebastian D, Imbernon M, Castano C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodriguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155: 172–187
-
(2013)
Cell
, vol.155
, pp. 172-187
-
-
Schneeberger, M.1
Dietrich, M.O.2
Sebastian, D.3
Imbernon, M.4
Castano, C.5
Garcia, A.6
Esteban, Y.7
Gonzalez-Franquesa, A.8
Rodriguez, I.C.9
Bortolozzi, A.10
Garcia-Roves, P.M.11
Gomis, R.12
Nogueiras, R.13
Horvath, T.L.14
Zorzano, A.15
Claret, M.16
-
42
-
-
84943641363
-
Impact of reduced ATGL-mediated adipocyte lipolysis on obesity-associated insulin resistance and inflammation in male mice
-
Schoiswohl G, Stefanovic-Racic M, Menke MN, Wills RC, Surlow BA, Basantani MK, Sitnick MT, Cai L, Yazbeck CF, Stolz DB, Pulinilkunnil T, O'Doherty RM, Kershaw EE (2015) Impact of reduced ATGL-mediated adipocyte lipolysis on obesity-associated insulin resistance and inflammation in male mice. Endocrinology 156: 3610–3624
-
(2015)
Endocrinology
, vol.156
, pp. 3610-3624
-
-
Schoiswohl, G.1
Stefanovic-Racic, M.2
Menke, M.N.3
Wills, R.C.4
Surlow, B.A.5
Basantani, M.K.6
Sitnick, M.T.7
Cai, L.8
Yazbeck, C.F.9
Stolz, D.B.10
Pulinilkunnil, T.11
O'Doherty, R.M.12
Kershaw, E.E.13
-
43
-
-
84859448265
-
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
-
Sebastian D, Hernandez-Alvarez MI, Segales J, Sorianello E, Munoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, Oresic M, Pich S, Burcelin R, Palacin M, Zorzano A (2012) Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis. Proc Natl Acad Sci USA 109: 5523–5528
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 5523-5528
-
-
Sebastian, D.1
Hernandez-Alvarez, M.I.2
Segales, J.3
Sorianello, E.4
Munoz, J.P.5
Sala, D.6
Waget, A.7
Liesa, M.8
Paz, J.C.9
Gopalacharyulu, P.10
Oresic, M.11
Pich, S.12
Burcelin, R.13
Palacin, M.14
Zorzano, A.15
-
44
-
-
84887601613
-
A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells
-
Segales J, Paz JC, Hernandez-Alvarez MI, Sala D, Munoz JP, Noguera E, Pich S, Palacin M, Enriquez JA, Zorzano A (2013) A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab 305: E1208–E1221
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E1208-E1221
-
-
Segales, J.1
Paz, J.C.2
Hernandez-Alvarez, M.I.3
Sala, D.4
Munoz, J.P.5
Noguera, E.6
Pich, S.7
Palacin, M.8
Enriquez, J.A.9
Zorzano, A.10
-
45
-
-
53849143606
-
Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese
-
Tan CY, Vidal-Puig A (2008) Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese. Biochem Soc Trans 36: 935–940
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 935-940
-
-
Tan, C.Y.1
Vidal-Puig, A.2
-
46
-
-
33847755111
-
Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity
-
Tarnopolsky MA, Rennie CD, Robertshaw HA, Fedak-Tarnopolsky SN, Devries MC, Hamadeh MJ (2007) Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity. Am J Physiol Regul Integr Comp Physiol 292: R1271–R1278
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
, pp. R1271-R1278
-
-
Tarnopolsky, M.A.1
Rennie, C.D.2
Robertshaw, H.A.3
Fedak-Tarnopolsky, S.N.4
Devries, M.C.5
Hamadeh, M.J.6
-
47
-
-
33747702159
-
Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women
-
Toledo FG, Watkins S, Kelley DE (2006) Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women. J Clin Endocrinol Metab 91: 3224–3227
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3224-3227
-
-
Toledo, F.G.1
Watkins, S.2
Kelley, D.E.3
-
48
-
-
84907693957
-
Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications
-
Vernochet C, Damilano F, Mourier A, Bezy O, Mori MA, Smyth G, Rosenzweig A, Larsson NG, Kahn CR (2014) Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. FASEB J 28: 4408–4419
-
(2014)
FASEB J
, vol.28
, pp. 4408-4419
-
-
Vernochet, C.1
Damilano, F.2
Mourier, A.3
Bezy, O.4
Mori, M.A.5
Smyth, G.6
Rosenzweig, A.7
Larsson, N.G.8
Kahn, C.R.9
-
49
-
-
84889637452
-
Assessment of brown adipose tissue function
-
Virtue S, Vidal-Puig A (2013) Assessment of brown adipose tissue function. Front Physiol 4: 128
-
(2013)
Front Physiol
, vol.4
, pp. 128
-
-
Virtue, S.1
Vidal-Puig, A.2
-
50
-
-
80455135722
-
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
-
Wang H, Sreenivasan U, Hu H, Saladino A, Polster BM, Lund LM, Gong DW, Stanley WC, Sztalryd C (2011) Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria. J Lipid Res 52: 2159–2168
-
(2011)
J Lipid Res
, vol.52
, pp. 2159-2168
-
-
Wang, H.1
Sreenivasan, U.2
Hu, H.3
Saladino, A.4
Polster, B.M.5
Lund, L.M.6
Gong, D.W.7
Stanley, W.C.8
Sztalryd, C.9
-
51
-
-
84898648553
-
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
-
Wikstrom JD, Mahdaviani K, Liesa M, Sereda SB, Si Y, Las G, Twig G, Petrovic N, Zingaretti C, Graham A, Cinti S, Corkey BE, Cannon B, Nedergaard J, Shirihai OS (2014) Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J 33: 418–436
-
(2014)
EMBO J
, vol.33
, pp. 418-436
-
-
Wikstrom, J.D.1
Mahdaviani, K.2
Liesa, M.3
Sereda, S.B.4
Si, Y.5
Las, G.6
Twig, G.7
Petrovic, N.8
Zingaretti, C.9
Graham, A.10
Cinti, S.11
Corkey, B.E.12
Cannon, B.13
Nedergaard, J.14
Shirihai, O.S.15
-
52
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, Vonderfecht S, Hecht R, Li YS, Lindberg RA, Chen JL, Jung DY, Zhang Z, Ko HJ, Kim JK, Veniant MM (2009) Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 58: 250–259
-
(2009)
Diabetes
, vol.58
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
Stanislaus, S.4
Chen, M.5
Sivits, G.6
Vonderfecht, S.7
Hecht, R.8
Li, Y.S.9
Lindberg, R.A.10
Chen, J.L.11
Jung, D.Y.12
Zhang, Z.13
Ko, H.J.14
Kim, J.K.15
Veniant, M.M.16
-
53
-
-
84994257417
-
Adipose-specific deficiency of fumarate hydratase in mice protects against obesity, hepatic steatosis and insulin resistance
-
Yang H, Wu JW, Wang SP, Severi I, Sartini L, Frizzell N, Cinti S, Yang G, Mitchell GA (2016) Adipose-specific deficiency of fumarate hydratase in mice protects against obesity, hepatic steatosis and insulin resistance. Diabetes 65: 3396–3409
-
(2016)
Diabetes
, vol.65
, pp. 3396-3409
-
-
Yang, H.1
Wu, J.W.2
Wang, S.P.3
Severi, I.4
Sartini, L.5
Frizzell, N.6
Cinti, S.7
Yang, G.8
Mitchell, G.A.9
-
54
-
-
84923107023
-
Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment
-
Yu J, Zhang S, Cui L, Wang W, Na H, Zhu X, Li L, Xu G, Yang F, Christian M, Liu P (2015) Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment. Biochim Biophys Acta 1853: 918–928
-
(2015)
Biochim Biophys Acta
, vol.1853
, pp. 918-928
-
-
Yu, J.1
Zhang, S.2
Cui, L.3
Wang, W.4
Na, H.5
Zhu, X.6
Li, L.7
Xu, G.8
Yang, F.9
Christian, M.10
Liu, P.11
-
55
-
-
68949116271
-
Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
-
Zorzano A, Liesa M, Palacin M (2009) Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes. Int J Biochem Cell Biol 41: 1846–1854
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1846-1854
-
-
Zorzano, A.1
Liesa, M.2
Palacin, M.3
|